The Qi of Body, Mind, and Spirit: A Contextual Perspective on the Elusive Nature of Qi
CONCLUSIONS: Qi-nature can vary among gross, subtle, and causal levels. These levels can coexist and overlap during treatments of patients. This tripartite explanation may represent the Oriental pictograms better and be consistent with the philosophical root of Chinese Medicine-the Tao.PMID:38659729 | PMC:PMC11036150 | DOI:10.1089/acu.2023.0071 (Source: Acupuncture in Medicine)
Source: Acupuncture in Medicine - April 25, 2024 Category: Complementary Medicine Authors: Michael T Greenwood Source Type: research
Simultaneous occurrence of transient global amnesia and Takotsubo syndrome triggered by caring for a terminally ill relative
Key Clinical MessageTakotsubo syndrome and transient global amnesia can occur simultaneously, not only in the context of acute but also long-standing emotional stress. Probably, hypothyroidism and migraine make the patient more susceptible to both of these disorders. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 25, 2024 Category: General Medicine Authors: Claudia St öllberger,
Josef Finsterer Tags: CASE REPORT Source Type: research
The burden of headache disorders in the adult general population of the Kingdom of Saudi Arabia: estimates from a cross-sectional population-based study including a health-care needs assessment
ConclusionA very high symptom burden is associated with a commensurately high burden of impaired participation. The economic cost appears to be enormous. Over a third of the adult population are revealed to require headache-related health care on the basis of being likely to benefit, demanding highly efficient organization of care. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - April 25, 2024 Category: Neurology Source Type: research
Real-world effectiveness and satisfaction with intravenous eptinezumab treatment in patients with chronic migraine: REVIEW, an observational, multi-site, US-based study
ConclusionThis real-world evidence study demonstrated high overall satisfaction with the effectiveness of eptinezumab treatment for CM among most patients and their physicians. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - April 25, 2024 Category: Neurology Source Type: research
Dihydroergotamine mesylate nasal spray: an acute treatment option for migraine in adults
Expert Rev Neurother. 2024 Apr 24:1-10. doi: 10.1080/14737175.2024.2342446. Online ahead of print.ABSTRACTINTRODUCTION: Although the landscape of migraine symptomatic treatment has been enriched by novel effective drugs, it is mandatory to critically reappraise older molecules to ascertain whether they could still represent reliable alternatives in specific endophenotypes of patients or migraine attacks. Among these, dihydroergotamine (DHE) nasal spray has been shown to be effective and is characterized by greater tolerability and manageability than the parenteral DHE formulation.AREAS COVERED: In this narrative review, th...
Source: Expert Review of Neurotherapeutics - April 24, 2024 Category: Neurology Authors: Marcello Silvestro Ilaria Orologio Alessandro Tessitore Francesca Trojsi Gioacchino Tedeschi Antonio Russo Source Type: research
Pediatric torticollis: clinical report and predictors of urgency of 1409 cases
ConclusionOur study shows that an urgent condition most commonly occur in patients presenting with history of trauma or headache, vomiting and torticollis for more than 24 h should undergo further diagnostic evaluation and short-term follow-up, restricting invasive or expensive investigations to patients with clinical suspicion of an underlying harmful condition. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - April 24, 2024 Category: Pediatrics Source Type: research
Safety, Tolerability, and Pharmacokinetics of Oral BI 1358894 in Healthy Japanese Male Volunteers
ConclusionBI 1358894 was well tolerated with a favorable pharmacokinetic profile in Japanese male HVs, similar to findings from a previous study in Caucasian male HVs.Trial RegistrationClinicalTrials.gov (NCT03875001; 08-Mar-2019). (Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - April 24, 2024 Category: Drugs & Pharmacology Source Type: research
Health-related quality of life, work ability and disability among individuals with persistent post-dural puncture headache
ConclusionThis study stresses the burden of pPDPH in terms of substantial disability, limited quality of life, mental health concerns, and significant impact on the ability to work. The study highlights the long-term impact of pPDPH on individuals, emphasizing the need for timely diagnosis and effective treatment. It underscores the complexity of managing pPDPH and calls for further research into its long-term effects on patient health and HRQoL. (Source: The Journal of Headache and Pain)
Source: The Journal of Headache and Pain - April 24, 2024 Category: Neurology Source Type: research
Female-selective mechanisms promoting migraine
AbstractSexual dimorphism has been revealed for many neurological disorders including chronic pain. Prelicinal studies and post-mortem analyses from male and female human donors reveal sexual dimorphism of nociceptors at transcript, protein and functional levels suggesting different mechanisms that may promote pain in men and women. Migraine is a common female-prevalent neurological disorder that is characterized by painful and debilitating headache. Prolactin is a neurohormone that circulates at higher levels in females and that has been implicated clinically in migraine. Prolactin sensitizes sensory neurons from female m...
Source: The Journal of Headache and Pain - April 24, 2024 Category: Neurology Source Type: research
Psilocybin therapy and anorexia nervosa: a narrative review of safety considerations for researchers and clinicians
ConclusionEarly evidence suggests that psilocybin therapy is well-tolerated in individuals with AN. Understanding the unique medical complications of AN, and how they may be impacted by common physiologic adverse effects of psilocybin administration, leads to tailored risk mitigation strategies to enhance safety and tolerability of this novel intervention. (Source: Journal of Eating Disorders)
Source: Journal of Eating Disorders - April 24, 2024 Category: Eating Disorders & Weight Management Source Type: research
Neuropsychiatric complications of coronavirus disease 2019: Mount Sinai Health System cohort study
ConclusionNeuropsychiatric complications of COVID-19, especially AMS, were common, varied, and associated with in-hospital mortality in a diverse multicenter cohort at an epicenter of the COVID-19 pandemic. (Source: Journal of Neurology)
Source: Journal of Neurology - April 24, 2024 Category: Neurology Source Type: research
Safety and efficacy of transvenous embolization of cerebrospinal fluid-venous fistula in patients with spontaneous intracranial hypotension
CONCLUSION: Transvenous embolization of CSFVF allowed high rates of clinical improvement with no morbidity related to the treatment.PMID:38651327 | DOI:10.1177/15910199241247698 (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - April 23, 2024 Category: Radiology Authors: Federico Cagnazzo Anne Ducros Gaetano Risi Mahmoud Charif Lucas Corti Francesca Rapido Emmanuelle Le Bars Nicolas Lonjon Vincent Costalat Source Type: research
Changes in Physiological Traits, Gene Expression and Phytochemical Profile of Mentha piperita in Response to Elicitor
The objective of this research is to investigate the expression of essential genes in the menthol pathway of Mentha piperita, including Pulegone reductase (Pr), Menthofuran synthase (Mfs), and limonene synthase (Ls) using qPCR, physiological analysis and essential oil composition in response to methyl jasmonate (MeJA) (0.5 mM) elicitation. Physiological analysis showed that 0.5 mM MeJA triggers defensive responsiveness in Mentha piperita by increasing superoxide dismutase (SOD) and Peroxidase (POD) enzymes activity. The highest transcript levels of Pr and Mfs genes were observed during 8 and 12 h after treatment respective...
Source: Biochemical Genetics - April 23, 2024 Category: Genetics & Stem Cells Authors: Soheila Afkar Ghasem Karimzadeh Source Type: research
