Burden of Wilson Disease among patients and care partners in the United States: results from a cross-sectional survey
Conclusion: This study highlights the burden of WD experienced by patients and WD-CPs, with patients experiencing high treatment burden, comorbidity burden and healthcare resource utilization, and WD-CPs experiencing high impact of caring, including impact on employment and self-esteem.PMID:38571385 | DOI:10.1080/03007995.2024.2337684 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - April 4, 2024 Category: Research Authors: Jon Vlasnik M Janelle Cambron-Mellott Halley Costantino Mary Kunjappu Source Type: research
The Ultra-Long-Term Sleep study: Design, rationale, data stability and user perspective
This study provides compelling evidence for the feasibility of longitudinal sleep monitoring during everyday life utilizing subcutaneous electroencephalography in healthy subjects, showcasing excellent signal stability, adherence and user experience. The amassed subcutaneous electroencephalography data constitutes the largest dataset of its kind, and is poised to significantly advance our understanding of day-to-day variations in normal sleep and provide key insights into subjective and objective sleep quality.PMID:38572813 | DOI:10.1111/jsr.14197 (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - April 4, 2024 Category: Sleep Medicine Authors: Esben Ahrens Poul Jennum Jonas Duun-Henriksen Helle W S Borregaard Sofie Sylvest Nielsen Nick Taptiklis Francesca Cormack Bjarki Ditlev Djurhuus Preben Hom øe Troels W Kj ær Martin Christian Hemmsen Source Type: research
Symptoms and Severity of COVID-19 in Patients with Immune-Mediated Inflammatory Diseases: Experience of a University Medical Center
CONCLUSION: Our IMID patients have a high rate of vaccination against SARS-CoV-2. Data show a significantly longer infection-free survival in vaccinated IMID patients as compared to unvaccinated patients. Discrimination between symptoms of COVID-19 and a concomitant inflammatory disease is difficult as complaints might be overlapping. This trial is registered with DRKS00028880.PMID:38571561 | PMC:PMC10990649 | DOI:10.1155/2024/6627035 (Source: Autoimmune Diseases)
Source: Autoimmune Diseases - April 4, 2024 Category: Allergy & Immunology Authors: Tobias Schlosser Marco Krasselt Louis Elsing Martin Hecker Babett Holler Albrecht Hoffmeister Source Type: research
Temporomandibular Disorders, Bruxism and Headaches
Neurol Clin. 2024 May;42(2):573-584. doi: 10.1016/j.ncl.2023.12.010. Epub 2024 Jan 13.ABSTRACTTemporomandibular disorders (TMDs) and headache disorders are highly prevalent in the population. TMDs can present headache symptoms as a secondary headache and, in addition, be comorbid with primary headache disorders. This overlap has significant clinical implications for which it is essential for the physician to be aware, and they should screen for the potential presence of TMDs in a headache patient. Bruxism is a parafunctional behavior also prevalent in the population which has a role in TMDs and may influence headache sympt...
Source: Pain Physician - April 4, 2024 Category: Anesthesiology Authors: Marcela Romero-Reyes Jennifer P Bassiur Source Type: research
The Ultra-Long-Term Sleep study: Design, rationale, data stability and user perspective
This study provides compelling evidence for the feasibility of longitudinal sleep monitoring during everyday life utilizing subcutaneous electroencephalography in healthy subjects, showcasing excellent signal stability, adherence and user experience. The amassed subcutaneous electroencephalography data constitutes the largest dataset of its kind, and is poised to significantly advance our understanding of day-to-day variations in normal sleep and provide key insights into subjective and objective sleep quality.PMID:38572813 | DOI:10.1111/jsr.14197 (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - April 4, 2024 Category: Sleep Medicine Authors: Esben Ahrens Poul Jennum Jonas Duun-Henriksen Helle W S Borregaard Sofie Sylvest Nielsen Nick Taptiklis Francesca Cormack Bjarki Ditlev Djurhuus Preben Hom øe Troels W Kj ær Martin Christian Hemmsen Source Type: research
Burden of Wilson Disease among patients and care partners in the United States: results from a cross-sectional survey
Conclusion: This study highlights the burden of WD experienced by patients and WD-CPs, with patients experiencing high treatment burden, comorbidity burden and healthcare resource utilization, and WD-CPs experiencing high impact of caring, including impact on employment and self-esteem.PMID:38571385 | DOI:10.1080/03007995.2024.2337684 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - April 4, 2024 Category: Research Authors: Jon Vlasnik M Janelle Cambron-Mellott Halley Costantino Mary Kunjappu Source Type: research
Neuroprotective effects of methanolic extract from Chuanxiong Rhizoma in mice with middle cerebral artery occlusion-induced ischemic stroke: suppression of astrocyte- and microglia-related inflammatory response
In traditional Asian medicine, dried rhizomes of Ligusticum chuanxiong Hort. (Chuanxiong Rhizoma [CR]) have long been used to treat pain disorders that affect the head and face such as headaches. Furthermore, the... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - April 4, 2024 Category: Complementary Medicine Authors: Chiyeon Lim, Sehyun Lim, So-Jung Moon and Suin Cho Tags: Research Source Type: research
An Unusual Case of Brain Abscess in a HIV Negative Host
A 45-years-old previously healthy male presented with intermittent diffuse chronic headache of mild to moderate grade intensity for 8 months initially 1-2 times a month now daily episodes with increased severity since 1 month partially relieved with analgesics with blurring of vision in bilateral eyes. He also reported an intermittent fever of up to 102 F for two weeks around two months back. On examination, vitals were stable with neurological examination showing the presence of neck rigidity only, with normal cranial nerve and fundus examination. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - April 4, 2024 Category: General Medicine Authors: Harleen Sood, Nupur Pradhan, Harpreet Singh, Deba Prasad Dhibhar, Murali Krishna Bethanbhatla, Harsimran Kaur, Kirti Gupta, Vikas Suri, Ashish Bhalla Tags: Clinical Communication to the Editor Source Type: research
Idiopathic Intracranial Hypertension After Abrupt Cessation of Medication: A Case Report of Abrupt Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Cessation and Review of the Literature
AbstractPurpose of ReviewThe purpose of this review is two-fold: (1) to discuss a case report of idiopathic intracranial hypertension (IIH) after abrupt cessation of a glucagon-like peptide-1 (GLP-1) receptor agonist with resultant rapid weight gain and (2) to review the literature regarding the potential role of GLP-1 receptor agonists in the treatment of IIH as well as potential pitfalls.Recent FindingsGLP-1 receptor agonists have become widely used to treat obesity. Obesity is a known risk factor for the development of IIH, though the precise pathophysiology is unclear. GLP-1 receptor agonists may help treat IIH by prom...
Source: Current Pain and Headache Reports - April 4, 2024 Category: Neurology Source Type: research
Long-term outcomes of hospitalized patients with SARS-CoV-2/COVID-19 with and without neurological involvement: 3-year follow-up assessment
by Anna Eligulashvili, Moshe Gordon, Jimmy S. Lee, Jeylin Lee, Shiv Mehrotra-Varma, Jai Mehrotra-Varma, Kevin Hsu, Imanyah Hilliard, Kristen Lee, Arleen Li, Muhammed Amir Essibayi, Judy Yee, David J. Altschul, Emad Eskandar, Mark F. Mehler, Tim Q. Duong
BackgroundAcute neurological manifestation is a common complication of acute Coronavirus Disease 2019 (COVID-19) disease. This retrospective cohort study investigated the 3-year outcomes of patients with and without significant neurological manifestations during initial COVID-19 hospitalization. Methods and findingsPatients hospitalized for Severe Acute Respiratory Syndrome...
Source: PLoS Medicine - April 4, 2024 Category: Internal Medicine Authors: Anna Eligulashvili Source Type: research
Pituitary Adenoma Prevalence and Characteristics of Omani Patients: A Single Center Experience
CONCLUSIONS: In our investigation, PA was primarily prevalent among Omani female patients, and the most common subtype of pituitary tumors was prolactinomas. The most common presentation symptom was headaches; most female patients had menstrual irregularities. Medical treatment was the primary approach for the applicable types of PAs, while surgery and radiotherapy were found to be secondary and tertiary treatment options, respectively.PMID:38567166 | PMC:PMC10985075 | DOI:10.5001/omj.2024.44 (Source: Oman Medical Journal)
Source: Oman Medical Journal - April 3, 2024 Category: Middle East Health Authors: Abdullah M Al Futaisi Asma M Al Marzouqi Mohammed A Al Abri Maha Z Al Riyami Source Type: research
