Diagnostic value and safety of medical thoracoscopy under local anesthesia for unexplained diffuse interstitial lung disease: A retrospective study
CONCLUSIONS: Medical thoracoscopic lung biopsy appears a safe and effective method for diagnosing diffuse ILD of unknown cause but further prospective studies, with larger numbers, including comparison with other established techniques are required.PMID:36206158 | DOI:10.1177/14799731221133389 (Source: Respiratory Care)
Source: Respiratory Care - October 7, 2022 Category: Respiratory Medicine Authors: Lei Zhang Tian Xie Yaqing Li Bingli Zhang Yihui Fu Yipeng Ding Haihong Wu Source Type: research
Diagnostic value and safety of medical thoracoscopy under local anesthesia for unexplained diffuse interstitial lung disease: A retrospective study
CONCLUSIONS: Medical thoracoscopic lung biopsy appears a safe and effective method for diagnosing diffuse ILD of unknown cause but further prospective studies, with larger numbers, including comparison with other established techniques are required.PMID:36206158 | DOI:10.1177/14799731221133389 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - October 7, 2022 Category: Respiratory Medicine Authors: Lei Zhang Tian Xie Yaqing Li Bingli Zhang Yihui Fu Yipeng Ding Haihong Wu Source Type: research
Diagnostic value and safety of medical thoracoscopy under local anesthesia for unexplained diffuse interstitial lung disease: A retrospective study
CONCLUSIONS: Medical thoracoscopic lung biopsy appears a safe and effective method for diagnosing diffuse ILD of unknown cause but further prospective studies, with larger numbers, including comparison with other established techniques are required.PMID:36206158 | DOI:10.1177/14799731221133389 (Source: Respiratory Care)
Source: Respiratory Care - October 7, 2022 Category: Respiratory Medicine Authors: Lei Zhang Tian Xie Yaqing Li Bingli Zhang Yihui Fu Yipeng Ding Haihong Wu Source Type: research
Diagnostic value and safety of medical thoracoscopy under local anesthesia for unexplained diffuse interstitial lung disease: A retrospective study
CONCLUSIONS: Medical thoracoscopic lung biopsy appears a safe and effective method for diagnosing diffuse ILD of unknown cause but further prospective studies, with larger numbers, including comparison with other established techniques are required.PMID:36206158 | DOI:10.1177/14799731221133389 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - October 7, 2022 Category: Respiratory Medicine Authors: Lei Zhang Tian Xie Yaqing Li Bingli Zhang Yihui Fu Yipeng Ding Haihong Wu Source Type: research
A Descriptive Analysis of Patients Undergoing Cytoreductive Surgery for the First Peritoneal Recurrence from Adult Granulosa Cell Tumours: Focus on Disease Distribution, Morphology of Peritoneal Disease and the Role of HIPEC — a Retrospective Study by INDEPSO
AbstractThe aim of the present study was to report the clinical outcome and factors affecting survival in patients with first recurrence of AGC treated with cytoreductive surgery with or without HIPEC. The second aim was to study the disease distribution in the peritoneal cavity according to the peritoneal carcinomatosis index (PCI) and the morphology of peritoneal deposits. In this retrospective multicentric study, all patients of adult granulosa cell tumor with peritoneal recurrence were treated with CRS with or without HIPEC. Relevant clinical and demographic data were captured. Multivariable logistic regression was per...
Source: Indian Journal of Surgical Oncology - September 26, 2022 Category: Cancer & Oncology Source Type: research
Malignant granular cell tumor in the thoracic wall: A case report
Granulosa cell tumor (GCT) is a rare tumor that originates from neural/Schwann cells. GCTs can occur at any age and at any site in the body. The most common site is the tongue, followed by the mammary gland, upper respiratory tract ( throat and bronchus), and gastrointestinal tract (esophagus, large intestine and perianal area, stomach, small intestine, and bile duct). Malignant GCTs account for less than 1%–2% of all GCTs. Fewer than five GCTs in the thoracic wall have been reported, almost all of these benign. Here, we report a new case of malignant GCT of the thoracic wall, with rib invasion and pleural metastasis, in...
Source: Frontiers in Oncology - September 20, 2022 Category: Cancer & Oncology Source Type: research
Adult-type granulosa cell tumor of the ovary
Am J Cancer Res. 2022 Aug 15;12(8):3495-3511. eCollection 2022.ABSTRACTAdult-type Granulosa Cell Tumor of the Ovary (AGCT) is a relatively rare subtype of ovarian cancer, accounting for 2-4% of all ovarian cancer. AGCT originates from proliferating normal preovulatory granulosa cells (GCs) and retains several features of those GCs. The hormonal features of AGCT explain the clinical manifestations and provide reliable markers for early diagnosis and recurrence prediction of the disease. Most AGCT patients are diagnosed at an early stage and usually demonstrate a better prognosis than patients with other types of ovarian can...
Source: Cell Research - September 19, 2022 Category: Cytology Authors: Xiuwen Li Bo Tian Mengyan Liu Chunlei Miao Di Wang Source Type: research
Single-nucleus RNA Sequencing reveals the mechanism of cigarette smoke exposure on diminished ovarian reserve in mice
Ecotoxicol Environ Saf. 2022 Sep 15;245:114093. doi: 10.1016/j.ecoenv.2022.114093. Online ahead of print.ABSTRACTThe systematic toxicological mechanism of cigarette smoke (CS) on ovarian reserve has not been extensively investigated. Female 8-week-old C57BL/6 mice at peak fertility were exposed to CS or indoor air only for 30 days (100 mice per group) and the effects of CS on ovarian reserve were assessed using Single-Nucleus RNA Sequencing (snRNA-seq). In addition, further biochemical experiments, including immunohistochemical staining, ELISA, immunofluorescence staining, transmission electron microscopy, cell counting ki...
Source: Ecotoxicology and Environmental Safety - September 18, 2022 Category: Environmental Health Authors: Fang Li Ying Wang Mengting Xu Nengyin Hu Jianing Miao Yanhui Zhao Lili Wang Source Type: research
Single-nucleus RNA Sequencing reveals the mechanism of cigarette smoke exposure on diminished ovarian reserve in mice
Ecotoxicol Environ Saf. 2022 Sep 16;245:114093. doi: 10.1016/j.ecoenv.2022.114093. Online ahead of print.ABSTRACTThe systematic toxicological mechanism of cigarette smoke (CS) on ovarian reserve has not been extensively investigated. Female 8-week-old C57BL/6 mice at peak fertility were exposed to CS or indoor air only for 30 days (100 mice per group) and the effects of CS on ovarian reserve were assessed using Single-Nucleus RNA Sequencing (snRNA-seq). In addition, further biochemical experiments, including immunohistochemical staining, ELISA, immunofluorescence staining, transmission electron microscopy, cell counting ki...
Source: Ecotoxicology and Environmental Safety - September 18, 2022 Category: Environmental Health Authors: Fang Li Ying Wang Mengting Xu Nengyin Hu Jianing Miao Yanhui Zhao Lili Wang Source Type: research
Juvenile Granulosa Cell Tumor Mimicking HAIR-AN in a 4-Year-Old: A Case Report
We present a case of a JGCT which presented with signs of prepubertal hyperandrogenism and insulin resistance to highlight the possible interaction between hyperandrogenemia and hyperinsulinism. We conducted chart review of a rare androgen secreting JGCT accompanied by hyperinsulinemia in a prepubertal patient. A 4-year-old girl presented with acanthosis nigricans and hyperinsulinism mimicking the Hyperandrogenism Insulin Resistance and Acanthosis Nigricans (HAIR-AN) syndrome at an age much younger than is typical for this diagnosis. Laboratory studies revealed elevated insulin, inhibin A and B, and total testosterone. All...
Source: Cell Research - September 16, 2022 Category: Cytology Authors: Rachel Choe Kim Ilya Goldberg Trevor Van Brunt Hamama Tul-Bushra Rebecca Batiste Andrew H Lane Helen Hsieh Source Type: research
Juvenile Granulosa Cell Tumor Mimicking HAIR-AN in a 4-Year-Old: A Case Report
We present a case of a JGCT which presented with signs of prepubertal hyperandrogenism and insulin resistance to highlight the possible interaction between hyperandrogenemia and hyperinsulinism. We conducted chart review of a rare androgen secreting JGCT accompanied by hyperinsulinemia in a prepubertal patient. A 4-year-old girl presented with acanthosis nigricans and hyperinsulinism mimicking the Hyperandrogenism Insulin Resistance and Acanthosis Nigricans (HAIR-AN) syndrome at an age much younger than is typical for this diagnosis. Laboratory studies revealed elevated insulin, inhibin A and B, and total testosterone. All...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - September 16, 2022 Category: Endocrinology Authors: Rachel Choe Kim Ilya Goldberg Trevor Van Brunt Hamama Tul-Bushra Rebecca Batiste Andrew H Lane Helen Hsieh Source Type: research
