Imaging in gynecological disease: clinical and ultrasound characteristics of recurrent ovarian stromal cell tumors
CONCLUSIONS: Some granulosa cell and Sertoli-Leydig cell recurrences manifest typical ultrasound patterns. However, some were described as unilocular cysts. Unilocular cysts are usually classified as benign, but in patients in follow-up for a granulosa cell tumor or Sertoli-Leydig cell tumor, they should be considered suspicious of recurrence. This article is protected by copyright. All rights reserved.PMID:37774092 | DOI:10.1002/uog.27504 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - September 29, 2023 Category: Radiology Authors: F Moro M T Giudice G Bolomini M C Moruzzi F Mascilini L Quagliozzi F Ciccarone G Scambia A Fagotti L Valentin A C Testa Source Type: research
Imaging in gynecological disease: clinical and ultrasound characteristics of recurrent ovarian stromal cell tumors
CONCLUSIONS: Some granulosa cell and Sertoli-Leydig cell recurrences manifest typical ultrasound patterns. However, some were described as unilocular cysts. Unilocular cysts are usually classified as benign, but in patients in follow-up for a granulosa cell tumor or Sertoli-Leydig cell tumor, they should be considered suspicious of recurrence. This article is protected by copyright. All rights reserved.PMID:37774092 | DOI:10.1002/uog.27504 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - September 29, 2023 Category: Radiology Authors: F Moro M T Giudice G Bolomini M C Moruzzi F Mascilini L Quagliozzi F Ciccarone G Scambia A Fagotti L Valentin A C Testa Source Type: research
Imaging in gynecological disease: clinical and ultrasound characteristics of recurrent ovarian stromal cell tumors
CONCLUSIONS: Some granulosa cell and Sertoli-Leydig cell recurrences manifest typical ultrasound patterns. However, some were described as unilocular cysts. Unilocular cysts are usually classified as benign, but in patients in follow-up for a granulosa cell tumor or Sertoli-Leydig cell tumor, they should be considered suspicious of recurrence. This article is protected by copyright. All rights reserved.PMID:37774092 | DOI:10.1002/uog.27504 (Source: The Ultrasound Review of Obstetrics and Gynecology)
Source: The Ultrasound Review of Obstetrics and Gynecology - September 29, 2023 Category: Radiology Authors: F Moro M T Giudice G Bolomini M C Moruzzi F Mascilini L Quagliozzi F Ciccarone G Scambia A Fagotti L Valentin A C Testa Source Type: research
Acute Large Ovarian Cyst After Surgical Resection of Juvenile Granulosa Cell Tumor Stage 1C
Am Surg. 2023 Sep 25:31348231192064. doi: 10.1177/00031348231192064. Online ahead of print.ABSTRACTJuvenile granulosa cell tumors (JGCTs) are rare, though carry significant burden of morbidity and mortality. A 15-year-old menstruating female with abdominal pain was diagnosed with a large 22.3 cm pelvic mass. CA-125 and LDH were elevated. Exploratory laparotomy was undertaken due to lesion size, and left salpingo-oophorectomy with omentectomy was completed. Pathology confirmed JGCTs with focal disruption, consistent with Stage IC disease. Six weeks postoperatively, the patient experienced recurrent abdominal pain and ultras...
Source: The American Surgeon - September 26, 2023 Category: Surgery Authors: Brianna L Spencer Dimitra M Lotakis Sydni Imel K Elizabeth Speck Source Type: research
Acute Large Ovarian Cyst After Surgical Resection of Juvenile Granulosa Cell Tumor Stage 1C
Am Surg. 2023 Sep 25:31348231192064. doi: 10.1177/00031348231192064. Online ahead of print.ABSTRACTJuvenile granulosa cell tumors (JGCTs) are rare, though carry significant burden of morbidity and mortality. A 15-year-old menstruating female with abdominal pain was diagnosed with a large 22.3 cm pelvic mass. CA-125 and LDH were elevated. Exploratory laparotomy was undertaken due to lesion size, and left salpingo-oophorectomy with omentectomy was completed. Pathology confirmed JGCTs with focal disruption, consistent with Stage IC disease. Six weeks postoperatively, the patient experienced recurrent abdominal pain and ultras...
Source: The American Surgeon - September 26, 2023 Category: Surgery Authors: Brianna L Spencer Dimitra M Lotakis Sydni Imel K Elizabeth Speck Source Type: research
Acute Large Ovarian Cyst After Surgical Resection of Juvenile Granulosa Cell Tumor Stage 1C
Am Surg. 2023 Sep 25:31348231192064. doi: 10.1177/00031348231192064. Online ahead of print.ABSTRACTJuvenile granulosa cell tumors (JGCTs) are rare, though carry significant burden of morbidity and mortality. A 15-year-old menstruating female with abdominal pain was diagnosed with a large 22.3 cm pelvic mass. CA-125 and LDH were elevated. Exploratory laparotomy was undertaken due to lesion size, and left salpingo-oophorectomy with omentectomy was completed. Pathology confirmed JGCTs with focal disruption, consistent with Stage IC disease. Six weeks postoperatively, the patient experienced recurrent abdominal pain and ultras...
Source: The American Surgeon - September 26, 2023 Category: Surgery Authors: Brianna L Spencer Dimitra M Lotakis Sydni Imel K Elizabeth Speck Source Type: research
Bisphenol S and F affect cell cycle distribution and steroidogenic activity of human ovarian granulosa cells, but not primary granulosa tumour cells
Toxicol In Vitro. 2023 Sep 15:105697. doi: 10.1016/j.tiv.2023.105697. Online ahead of print.ABSTRACTBisphenol S (BPS) and F (BPF), a new generation of bisphenols (BPs), are the main substitutes for bisphenol A (BPA). Both have been detected in human body fluids. Importantly, bisphenols are structurally similar to oestrogen, the main sex hormone in females. Because bisphenols bind to nuclear oestrogen receptors (ESR1 and ESR2) and to membrane G-coupled receptor 30 (GPR30), they can disrupt ovarian function. Here, we reveal the molecular mechanism underlying the effects of BPS and BPF on the cell cycle and steroidogenesis in...
Source: Toxicology in Vitro - September 17, 2023 Category: Toxicology Authors: Paulina G łód Norbert Borski Justyna Gogola-Mruk Ma łgorzata Opydo Anna Ptak Source Type: research
Pediatric granular cell tumor of the larynx: A case report and literature review
J Cancer Res Ther. 2023 Aug;19(4):1070-1073. doi: 10.4103/jcrt.jcrt_2096_22.ABSTRACTAn 8-year-old child was admitted to our ENT department for a year because of a hoarse voice. An endoscopic examination displayed that a cystic, solid lesion can be seen in the right subglottis. The lesion was removed using a CO2 laser under general anesthesia. Postoperative histopathology confirmed granular cell tumor (GCT), S-100(+), vimentin (+), and SOX-10(+). GCT, also known as the Abrikossoff tumor, is a rare benign tumor that rarely occurs in the larynx, particularly in children. This case report emphasizes that considerable attention...
Source: Cell Research - September 7, 2023 Category: Cytology Authors: Jing Ke Junwei Xiong Juhong Zhang Haiyu Ma Wei Yuan Source Type: research
Roles of follicle stimulating hormone and sphingosine 1-phosphate co-administered in the process in mouse ovarian vitrification and transplantation
J Ovarian Res. 2023 Aug 24;16(1):173. doi: 10.1186/s13048-023-01206-1.ABSTRACTSome major challenges of ovarian tissue vitrification and transplantation include follicle apoptosis induced by cryopreservation and ischemia-reperfusion injury, as well as ovarian follicle loss during post-transplantation. This research aimed to investigate the protective effects and underlying mechanisms of follicle-stimulating hormone (FSH) and Sphingosine-1-phosphate (S1P) on vitrified and post-transplantation ovaries. Ovaries from 21-day-old mice were cryopreservation by vitrification with 0.3 IU/mL FSH, 2 µM S1P, and 0.3 IU/mL FSH + 2 µM ...
Source: Cell Research - August 24, 2023 Category: Cytology Authors: Fei Wang Yuan Tian Liwen Huang Tian Qin Wenye Ma Chengbin Pei Bo Xu Hang Han Xinrui Liu Pengge Pan Xiaoli Yu Qin Chang Yanrong Wang Shuya Zhang Xiuying Pei Source Type: research
TFE3 nuclear expression as a novel biomarker of ovarian sclerosing stromal tumors and associated with its histological morphology
J Ovarian Res. 2023 Aug 1;16(1):152. doi: 10.1186/s13048-023-01241-y.ABSTRACTSclerosing stromal tumors of the ovary are benign and tend to occur in youthful women with lobular structures at low frequencies. Three types of cells, including luteinized cells, short spindle myoid cells, and intermediate cells, are found in the lobules which abundant in the blood vessels. Currently, immunohistochemistry is used to detect normal follicles, sclerosing stromal tumors, granulosa cell tumors, and fibromas/thecomas. Our research results showed that transcription factor enhancer 3 (TFE3) was moderate to strong positive in the theca in...
Source: Cell Research - August 1, 2023 Category: Cytology Authors: Li Zhao Zhongfeng Yang Yan Zhou Yuping Liu Qiuping Luo Qingping Jiang Hui Wang Na Wang Source Type: research
