Exploring the Therapeutic Potential of Ginkgo biloba Polyphenols in Targeting Biomarkers of Colorectal Cancer: An In-Silico Evaluation
CONCLUSION: The study demonstrates the potential of G. biloba-derived molecules as effective anticancer agents for colorectal cancer. The identified ligands exhibit strong interactions with crucial CRC-related biomarkers, suggesting potential inhibition ability. Further in vitro and in vivo investigations are needed to validate and build upon these promising findings, advancing the development of novel and efficient CRC therapies.PMID:38318835 | DOI:10.2174/0115701638282497240124102345 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - February 6, 2024 Category: Drugs & Pharmacology Authors: Sarra Hamdani Hocine Allali Salim Bouchentouf Source Type: research
Exploring the Therapeutic Potential of Ginkgo biloba Polyphenols in Targeting Biomarkers of Colorectal Cancer: An In-Silico Evaluation
CONCLUSION: The study demonstrates the potential of G. biloba-derived molecules as effective anticancer agents for colorectal cancer. The identified ligands exhibit strong interactions with crucial CRC-related biomarkers, suggesting potential inhibition ability. Further in vitro and in vivo investigations are needed to validate and build upon these promising findings, advancing the development of novel and efficient CRC therapies.PMID:38318835 | DOI:10.2174/0115701638282497240124102345 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - February 6, 2024 Category: Drugs & Pharmacology Authors: Sarra Hamdani Hocine Allali Salim Bouchentouf Source Type: research
Exploring the Therapeutic Potential of Ginkgo biloba Polyphenols in Targeting Biomarkers of Colorectal Cancer: An In-Silico Evaluation
CONCLUSION: The study demonstrates the potential of G. biloba-derived molecules as effective anticancer agents for colorectal cancer. The identified ligands exhibit strong interactions with crucial CRC-related biomarkers, suggesting potential inhibition ability. Further in vitro and in vivo investigations are needed to validate and build upon these promising findings, advancing the development of novel and efficient CRC therapies.PMID:38318835 | DOI:10.2174/0115701638282497240124102345 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - February 6, 2024 Category: Drugs & Pharmacology Authors: Sarra Hamdani Hocine Allali Salim Bouchentouf Source Type: research
Exploring the Therapeutic Potential of Ginkgo biloba Polyphenols in Targeting Biomarkers of Colorectal Cancer: An In-Silico Evaluation
CONCLUSION: The study demonstrates the potential of G. biloba-derived molecules as effective anticancer agents for colorectal cancer. The identified ligands exhibit strong interactions with crucial CRC-related biomarkers, suggesting potential inhibition ability. Further in vitro and in vivo investigations are needed to validate and build upon these promising findings, advancing the development of novel and efficient CRC therapies.PMID:38318835 | DOI:10.2174/0115701638282497240124102345 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - February 6, 2024 Category: Drugs & Pharmacology Authors: Sarra Hamdani Hocine Allali Salim Bouchentouf Source Type: research
Exploring the Therapeutic Potential of Ginkgo biloba Polyphenols in Targeting Biomarkers of Colorectal Cancer: An In-Silico Evaluation
CONCLUSION: The study demonstrates the potential of G. biloba-derived molecules as effective anticancer agents for colorectal cancer. The identified ligands exhibit strong interactions with crucial CRC-related biomarkers, suggesting potential inhibition ability. Further in vitro and in vivo investigations are needed to validate and build upon these promising findings, advancing the development of novel and efficient CRC therapies.PMID:38318835 | DOI:10.2174/0115701638282497240124102345 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - February 6, 2024 Category: Drugs & Pharmacology Authors: Sarra Hamdani Hocine Allali Salim Bouchentouf Source Type: research
Exploring the Therapeutic Potential of Ginkgo biloba Polyphenols in Targeting Biomarkers of Colorectal Cancer: An In-Silico Evaluation
CONCLUSION: The study demonstrates the potential of G. biloba-derived molecules as effective anticancer agents for colorectal cancer. The identified ligands exhibit strong interactions with crucial CRC-related biomarkers, suggesting potential inhibition ability. Further in vitro and in vivo investigations are needed to validate and build upon these promising findings, advancing the development of novel and efficient CRC therapies.PMID:38318835 | DOI:10.2174/0115701638282497240124102345 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - February 6, 2024 Category: Drugs & Pharmacology Authors: Sarra Hamdani Hocine Allali Salim Bouchentouf Source Type: research
Exploring the Therapeutic Potential of Ginkgo biloba Polyphenols in Targeting Biomarkers of Colorectal Cancer: An In-Silico Evaluation
CONCLUSION: The study demonstrates the potential of G. biloba-derived molecules as effective anticancer agents for colorectal cancer. The identified ligands exhibit strong interactions with crucial CRC-related biomarkers, suggesting potential inhibition ability. Further in vitro and in vivo investigations are needed to validate and build upon these promising findings, advancing the development of novel and efficient CRC therapies.PMID:38318835 | DOI:10.2174/0115701638282497240124102345 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - February 6, 2024 Category: Drugs & Pharmacology Authors: Sarra Hamdani Hocine Allali Salim Bouchentouf Source Type: research
Exploring the Therapeutic Potential of Ginkgo biloba Polyphenols in Targeting Biomarkers of Colorectal Cancer: An In-Silico Evaluation
CONCLUSION: The study demonstrates the potential of G. biloba-derived molecules as effective anticancer agents for colorectal cancer. The identified ligands exhibit strong interactions with crucial CRC-related biomarkers, suggesting potential inhibition ability. Further in vitro and in vivo investigations are needed to validate and build upon these promising findings, advancing the development of novel and efficient CRC therapies.PMID:38318835 | DOI:10.2174/0115701638282497240124102345 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - February 6, 2024 Category: Drugs & Pharmacology Authors: Sarra Hamdani Hocine Allali Salim Bouchentouf Source Type: research
Exploring the Therapeutic Potential of Ginkgo biloba Polyphenols in Targeting Biomarkers of Colorectal Cancer: An In-Silico Evaluation
CONCLUSION: The study demonstrates the potential of G. biloba-derived molecules as effective anticancer agents for colorectal cancer. The identified ligands exhibit strong interactions with crucial CRC-related biomarkers, suggesting potential inhibition ability. Further in vitro and in vivo investigations are needed to validate and build upon these promising findings, advancing the development of novel and efficient CRC therapies.PMID:38318835 | DOI:10.2174/0115701638282497240124102345 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - February 6, 2024 Category: Drugs & Pharmacology Authors: Sarra Hamdani Hocine Allali Salim Bouchentouf Source Type: research
Memantine versus Ginkgo biloba Extract: A Comparative Study on Cognitive Dysfunction Treatment in a Novel Rat Model
This study also highlights the need for future research to focus on the positive benefits of herbal
medicines. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Planta Medica)
Source: Planta Medica - January 29, 2024 Category: Drugs & Pharmacology Authors: Allam, Essmat A. H. Assi, Abdel-Azim Badary, Dalia M. Farrag, Magda M. Y. Nicola, Mariam A. Tags: Original Papers Source Type: research
Effects and safety of Ginkgo biloba on blood metabolism in type 2 diabetes mellitus: a systematic review and meta-analysis
ConclusionIn conclusion, GKB might safely reduce the risk of peripheral arterial or even systemic cardiovascular disease. However, GKB did not directly improve lipid and blood glucose levels in T2DM patients.Systematic review registrationhttps://inplasy.com/, identifier INPLASY202350096. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - January 8, 2024 Category: Endocrinology Source Type: research
Ginkgo Leaf ‐Derived Carbon Supports for the Immobilization of Iron/Iron Phosphide Nanospheres for Electrocatalytic Hydrogen Evolution
Iron-catalyzed graphitization with subsequent phosphidation is used to prepare Gingko-leaf derived carbon-supports immobilized with iron and iron phosphide nanospheres. The most active catalyst shows excellent performance in the hydrogen evolution reaction (HER) in 0.5 m H2SO4, achieving a current density of 10 and 500 mA cm−2 at overpotentials of 92 and 346 mV, respectively. AbstractIron/iron phosphide nanospheres supported on ginkgo leaf-derived carbon (Fe&FeP@gl-C) are prepared using a post-phosphidation approach, with varying amounts of iron (Fe). The activity of the catalysts in the hydrogen evolution reactio...
Source: Small - January 4, 2024 Category: Nanotechnology Authors: Qichang Wang,
Zhaofu Fei,
Dekui Shen,
Chongbo Cheng,
Paul J. Dyson Tags: Research Article Source Type: research
Shuxuening Injection Inhibits Apoptosis and Reduces Myocardial Ischemia-Reperfusion Injury in Rats through PI3K/AKT Pathway
ConclusionSXNI protects against MIRI by activating the PI3K/AKT signaling pathway. (Source: Chinese Journal of Integrative Medicine)
Source: Chinese Journal of Integrative Medicine - December 28, 2023 Category: Internal Medicine Source Type: research
< em > Ginkgo biloba < /em > : Antioxidant Activity and In Silico Central Nervous System Potential
Curr Issues Mol Biol. 2023 Dec 1;45(12):9674-9691. doi: 10.3390/cimb45120604.ABSTRACTGinkgo biloba (GB) extracts have been used in clinical studies as an alternative therapy for Alzheimer's disease (AD), but the exact bioaction mechanism has not yet been elucidated. In this work, an in silico study on GB metabolites was carried out using SwissTargetPrediction to determine the proteins associated with AD. The resulting proteins, AChE, MAO-A, MAO-B, β-secretase and γ-secretase, were studied by molecular docking, resulting in the finding that kaempferol, quercetin, and luteolin have multitarget potential against AD. These c...
Source: Current Issues in Molecular Biology - December 22, 2023 Category: Molecular Biology Authors: Eduardo Su árez-González Jes ús Sandoval-Ramírez Jorge Flores-Hern ández Alan Carrasco-Carballo Source Type: research
< em > Ginkgo biloba < /em > : Antioxidant Activity and In Silico Central Nervous System Potential
Curr Issues Mol Biol. 2023 Dec 1;45(12):9674-9691. doi: 10.3390/cimb45120604.ABSTRACTGinkgo biloba (GB) extracts have been used in clinical studies as an alternative therapy for Alzheimer's disease (AD), but the exact bioaction mechanism has not yet been elucidated. In this work, an in silico study on GB metabolites was carried out using SwissTargetPrediction to determine the proteins associated with AD. The resulting proteins, AChE, MAO-A, MAO-B, β-secretase and γ-secretase, were studied by molecular docking, resulting in the finding that kaempferol, quercetin, and luteolin have multitarget potential against AD. These c...
Source: Current Issues in Molecular Biology - December 22, 2023 Category: Molecular Biology Authors: Eduardo Su árez-González Jes ús Sandoval-Ramírez Jorge Flores-Hern ández Alan Carrasco-Carballo Source Type: research
