Air pollution and plasma amyloid beta in a cohort of older adults: Evidence from the Ginkgo Evaluation of Memory study
We examined the association between fine particulate matter<2.5 μm in diameter (PM2.5), particulate matter<10 μm in diameter (PM10), nitrogen dioxide (NO2), and plasma based measures of Aβ1-40, Aβ1-42 and Aβ1-42/Aβ1-40 using data from 3044 dementia-free participants of the Ginkgo Evaluation of Memory Study (GEMS). Air pollution exposures were estimated at residential addresses that incorporated address histories dating back to 1980, resulting in one-, five-, 10- and 20- year exposure averages. Aβ was measured at baseline (2000-2002) and then again at the end of the study (2007-2008) allowing for linear regress...
Source: Environment International - February 11, 2023 Category: Environmental Health Authors: Anjum Hajat Christina Park Claire Adam Annette L Fitzpatrick Sindana D Ilango Cindy Leary Tanya Libby Oscar Lopez Erin O Semmens Joel D Kaufman Source Type: research

Ginkgo, fennel, and flaxseed can affect hormone release by porcine ovarian cells and modulate the effect of toluene
Reprod Biol. 2023 Feb 9;23(1):100736. doi: 10.1016/j.repbio.2023.100736. Online ahead of print.ABSTRACTExperimental studies have documented the toxic effects of toluene on the mammalian female reproductive processes. The aim of this in vitro study was to examine the potential of functional food plant extracts, namely, of ginkgo, fennel, and flaxseed, in modifying the toluene-induced effects on ovarian hormone release. Porcine granulosa cells were incubated with ginkgo, fennel, or flaxseed extracts (0, 1, 10, or 100 µg/mL) and/or toluene (10 µg/mL). Enzyme immunoassays were used in order to measure the release of progeste...
Source: Reproductive Biology - February 11, 2023 Category: Reproduction Medicine Authors: Alexander V Sirotkin Martina Macejkov á Adam Tarko Zuzana Fabova Saleh Alwasel Jan Kotwica Abdel Halim Harrath Source Type: research

Ginkgo, fennel, and flaxseed can affect hormone release by porcine ovarian cells and modulate the effect of toluene
Reprod Biol. 2023 Feb 9;23(1):100736. doi: 10.1016/j.repbio.2023.100736. Online ahead of print.ABSTRACTExperimental studies have documented the toxic effects of toluene on the mammalian female reproductive processes. The aim of this in vitro study was to examine the potential of functional food plant extracts, namely, of ginkgo, fennel, and flaxseed, in modifying the toluene-induced effects on ovarian hormone release. Porcine granulosa cells were incubated with ginkgo, fennel, or flaxseed extracts (0, 1, 10, or 100 µg/mL) and/or toluene (10 µg/mL). Enzyme immunoassays were used in order to measure the release of progeste...
Source: Reproductive Biology - February 11, 2023 Category: Reproduction Medicine Authors: Alexander V Sirotkin Martina Macejkov á Adam Tarko Zuzana Fabova Saleh Alwasel Jan Kotwica Abdel Halim Harrath Source Type: research

Investigating the efficacy of Ginkgo biloba on the cognitive function of patients undergoing treatment with electric shock: a double-blind clinical trial
This study aimed to investigate the effectiveness of Ginkgo biloba therapy on the cognitive function of patients treated with electroshock. In a double-blinded clinical trial, 80 patients with psychiatric disorders who were candidates for ECT in 2019 were randomly assigned to two groups: the intervention group (receiving Ginkgo biloba drug) and the control group (receiving placebo). We used the Mini-Mental State Examination (MMSE) and Wechsler Memory Scale Recipe III (WMS-III) questionnaires to evaluate the efficacy of the drug on the cognitive function at time 0, after 4 sessions and 72 hours post-final session of ECT. Th...
Source: Journal of Medicine and Life - February 10, 2023 Category: General Medicine Authors: Masoumeh Nazarinasab Forouzan Behrouzian Saeedeh Negahban Amirali Moghadam Sadegh Elham Zeynali Source Type: research