< em > Ginkgo biloba < /em > and Its Chemical Components in the Management of Alzheimer's Disease
Am J Chin Med. 2024 Apr 24:1-42. doi: 10.1142/S0192415X24500277. Online ahead of print.ABSTRACTThe pathogenesis of Alzheimer's disease (AD), a degenerative disease of the central nervous system, remains unclear. The main manifestations of AD include cognitive and behavioral disorders, neuropsychiatric symptoms, neuroinflammation, amyloid plaques, and neurofibrillary tangles. However, current drugs for AD once the dementia stage has been reached only treat symptoms and do not delay progression, and the research and development of targeted drugs for AD have reached a bottleneck. Thus, other treatment options are needed. Bioa...
Source: The American Journal of Chinese Medicine - April 24, 2024 Category: Complementary Medicine Authors: Yong Peng Quan Chen Ya-Hui Xue Hong Jin Shu Liu Miao-Qiao Du Shun-Yu Yao Source Type: research

GSE250020 Gene expression in PBMC treated with cilostazol,Ginkgo Biloba Extract and rosuvastatin
Contributors : Yi-Lin Chiu ; Chia-Ning FanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe primary objective for collecting RNA-seq data in this study was to uncover the molecular mechanisms through which various drug impacts cardiovascular health. Specifically, the study aimed to explore how these drugs affects monocyte-to-macrophage differentiation and endothelial cell functions, both of which are crucial in the pathogenesis of cardiovascular diseases. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - April 24, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Comprehensive Insights into Pathophysiology of Alzheimer's Disease: Herbal Approaches for Mitigating Neurodegeneration
In conclusion, a comprehensive understanding of the complex pathophysiology of AD and the exploration of herbal interventions offer a holistic approach to managing this devastating disease. Future research should address the limitations associated with herbal drugs and further evaluate the efficacy of promising natural products in clinical settings.PMID:38623983 | DOI:10.2174/0115672050309057240404075003 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - April 16, 2024 Category: Neurology Authors: Debasis Sen Sunny Rathee Vishal Pandey Sanjay K Jain Umesh K Patil Source Type: research

Comprehensive Insights into Pathophysiology of Alzheimer's Disease: Herbal Approaches for Mitigating Neurodegeneration
In conclusion, a comprehensive understanding of the complex pathophysiology of AD and the exploration of herbal interventions offer a holistic approach to managing this devastating disease. Future research should address the limitations associated with herbal drugs and further evaluate the efficacy of promising natural products in clinical settings.PMID:38623983 | DOI:10.2174/0115672050309057240404075003 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - April 16, 2024 Category: Neurology Authors: Debasis Sen Sunny Rathee Vishal Pandey Sanjay K Jain Umesh K Patil Source Type: research

Comprehensive Insights into Pathophysiology of Alzheimer's Disease: Herbal Approaches for Mitigating Neurodegeneration
In conclusion, a comprehensive understanding of the complex pathophysiology of AD and the exploration of herbal interventions offer a holistic approach to managing this devastating disease. Future research should address the limitations associated with herbal drugs and further evaluate the efficacy of promising natural products in clinical settings.PMID:38623983 | DOI:10.2174/0115672050309057240404075003 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - April 16, 2024 Category: Neurology Authors: Debasis Sen Sunny Rathee Vishal Pandey Sanjay K Jain Umesh K Patil Source Type: research

Comprehensive Insights into Pathophysiology of Alzheimer's Disease: Herbal Approaches for Mitigating Neurodegeneration
In conclusion, a comprehensive understanding of the complex pathophysiology of AD and the exploration of herbal interventions offer a holistic approach to managing this devastating disease. Future research should address the limitations associated with herbal drugs and further evaluate the efficacy of promising natural products in clinical settings.PMID:38623983 | DOI:10.2174/0115672050309057240404075003 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - April 16, 2024 Category: Neurology Authors: Debasis Sen Sunny Rathee Vishal Pandey Sanjay K Jain Umesh K Patil Source Type: research

< i > Ginkgo biloba < /i > attenuated detrimental inflammatory and oxidative events due to < i > Trypanosoma brucei rhodesiense < /i > in mice treated with melarsoprol
ConclusionUtilization of GB as an adjuvant therapy may ameliorate detrimental effects caused by T.b.r infection and MelB toxicity during late stage HAT. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - April 15, 2024 Category: Tropical Medicine Authors: Janet Khatenje Wendo Source Type: research

Transcriptomic analysis reveals Cilostazol's role in ameliorating cardiovascular disease: Inhibition of monocyte-to-macrophage differentiation and reduction of endothelial cell reactive oxygen species production
CONCLUSION: The findings offer a nuanced understanding of the advantages and mechanisms of cilostazol in CVD, uncovering novel therapeutic targets and strategies to enhance the clinical application of cilostazol and contributing to the broader implications of this therapy in cardiovascular health.PMID:38601627 | PMC:PMC11004659 | DOI:10.1016/j.heliyon.2024.e29194 (Source: Atherosclerosis)
Source: Atherosclerosis - April 11, 2024 Category: Cardiology Authors: Chia-Ning Fan Tsung-Neng Tsai Xin-Jie Lu Hsing-Fan Lai Chun-Hua Wang Yi-Lin Chiu Source Type: research

Food Habits of Raccoon Dogs at An Agricultural Area in Shikoku, Western Japan
Zoolog Sci. 2024 Apr;41(2):185-191. doi: 10.2108/zs230051.ABSTRACTThe diet of raccoon dogs, which live in close proximity to agricultural fields in Matsuyama, western Japan, was studied throughout the year by the fecal analysis method (n = 114). Fruits were most important, accounting for 30-40% of the diet except in winter. Crops were next in importance, accounting for 10-30%. It was characteristic that the proportion of crops was greater and more stable than in other "satoyama" or rural areas in Japan. Crops included rice (Oryza sativa), wheat, sesame (Sesamum indicum), strawberries (Fragaria × ananassa), kiwi fruit (Act...
Source: Zoological Science - April 8, 2024 Category: Zoology Authors: Seiki Takatsuki Masakazu Inaba Source Type: research

Food Habits of Raccoon Dogs at An Agricultural Area in Shikoku, Western Japan
Zoolog Sci. 2024 Apr;41(2):185-191. doi: 10.2108/zs230051.ABSTRACTThe diet of raccoon dogs, which live in close proximity to agricultural fields in Matsuyama, western Japan, was studied throughout the year by the fecal analysis method (n = 114). Fruits were most important, accounting for 30-40% of the diet except in winter. Crops were next in importance, accounting for 10-30%. It was characteristic that the proportion of crops was greater and more stable than in other "satoyama" or rural areas in Japan. Crops included rice (Oryza sativa), wheat, sesame (Sesamum indicum), strawberries (Fragaria × ananassa), kiwi fruit (Act...
Source: Zoological Science - April 8, 2024 Category: Zoology Authors: Seiki Takatsuki Masakazu Inaba Source Type: research

Food Habits of Raccoon Dogs at An Agricultural Area in Shikoku, Western Japan
Zoolog Sci. 2024 Apr;41(2):185-191. doi: 10.2108/zs230051.ABSTRACTThe diet of raccoon dogs, which live in close proximity to agricultural fields in Matsuyama, western Japan, was studied throughout the year by the fecal analysis method (n = 114). Fruits were most important, accounting for 30-40% of the diet except in winter. Crops were next in importance, accounting for 10-30%. It was characteristic that the proportion of crops was greater and more stable than in other "satoyama" or rural areas in Japan. Crops included rice (Oryza sativa), wheat, sesame (Sesamum indicum), strawberries (Fragaria × ananassa), kiwi fruit (Act...
Source: Zoological Science - April 8, 2024 Category: Zoology Authors: Seiki Takatsuki Masakazu Inaba Source Type: research

Food Habits of Raccoon Dogs at An Agricultural Area in Shikoku, Western Japan
Zoolog Sci. 2024 Apr;41(2):185-191. doi: 10.2108/zs230051.ABSTRACTThe diet of raccoon dogs, which live in close proximity to agricultural fields in Matsuyama, western Japan, was studied throughout the year by the fecal analysis method (n = 114). Fruits were most important, accounting for 30-40% of the diet except in winter. Crops were next in importance, accounting for 10-30%. It was characteristic that the proportion of crops was greater and more stable than in other "satoyama" or rural areas in Japan. Crops included rice (Oryza sativa), wheat, sesame (Sesamum indicum), strawberries (Fragaria × ananassa), kiwi fruit (Act...
Source: Zoological Science - April 8, 2024 Category: Zoology Authors: Seiki Takatsuki Masakazu Inaba Source Type: research

Food Habits of Raccoon Dogs at An Agricultural Area in Shikoku, Western Japan
Zoolog Sci. 2024 Apr;41(2):185-191. doi: 10.2108/zs230051.ABSTRACTThe diet of raccoon dogs, which live in close proximity to agricultural fields in Matsuyama, western Japan, was studied throughout the year by the fecal analysis method (n = 114). Fruits were most important, accounting for 30-40% of the diet except in winter. Crops were next in importance, accounting for 10-30%. It was characteristic that the proportion of crops was greater and more stable than in other "satoyama" or rural areas in Japan. Crops included rice (Oryza sativa), wheat, sesame (Sesamum indicum), strawberries (Fragaria × ananassa), kiwi fruit (Act...
Source: Zoological Science - April 8, 2024 Category: Zoology Authors: Seiki Takatsuki Masakazu Inaba Source Type: research

Food Habits of Raccoon Dogs at An Agricultural Area in Shikoku, Western Japan
Zoolog Sci. 2024 Apr;41(2):185-191. doi: 10.2108/zs230051.ABSTRACTThe diet of raccoon dogs, which live in close proximity to agricultural fields in Matsuyama, western Japan, was studied throughout the year by the fecal analysis method (n = 114). Fruits were most important, accounting for 30-40% of the diet except in winter. Crops were next in importance, accounting for 10-30%. It was characteristic that the proportion of crops was greater and more stable than in other "satoyama" or rural areas in Japan. Crops included rice (Oryza sativa), wheat, sesame (Sesamum indicum), strawberries (Fragaria × ananassa), kiwi fruit (Act...
Source: Zoological Science - April 8, 2024 Category: Zoology Authors: Seiki Takatsuki Masakazu Inaba Source Type: research

Food Habits of Raccoon Dogs at An Agricultural Area in Shikoku, Western Japan
Zoolog Sci. 2024 Apr;41(2):185-191. doi: 10.2108/zs230051.ABSTRACTThe diet of raccoon dogs, which live in close proximity to agricultural fields in Matsuyama, western Japan, was studied throughout the year by the fecal analysis method (n = 114). Fruits were most important, accounting for 30-40% of the diet except in winter. Crops were next in importance, accounting for 10-30%. It was characteristic that the proportion of crops was greater and more stable than in other "satoyama" or rural areas in Japan. Crops included rice (Oryza sativa), wheat, sesame (Sesamum indicum), strawberries (Fragaria × ananassa), kiwi fruit (Act...
Source: Zoological Science - April 8, 2024 Category: Zoology Authors: Seiki Takatsuki Masakazu Inaba Source Type: research