A strategy for quality control of ginkgo biloba preparations based on UPLC fingerprint analysis and multi-component separation combined with quantitative analysis
Many studies have assessed the fingerprint and quantitative analysis of Ginkgo biloba preparations, but the fingerprint mainly focuses on flavonoid glycosides. However, according to our previous study, the dif... (Source: Chinese Medicine)
Source: Chinese Medicine - June 16, 2022 Category: Complementary Medicine Authors: Li-na Liu, Hong-yu Jin, Zan Ke, Wei-yi Xu, Lei Sun and Shuang-cheng Ma Tags: Research Source Type: research

A flower-like ionic molecularly imprinted membrane for the deglycosylation of rutin
Anal Sci. 2022 Jun 15. doi: 10.1007/s44211-022-00125-3. Online ahead of print.ABSTRACTA kind of molecularly imprinted polymer based on ionic liquids (MIPIL) with flower-like shape was developed for the adsorption of rutin and its deglycosylated product. The MIPIL film was characterized by scanning electron microscope (SEM) and X-ray photo-electron spectroscopy (XPS). The adsorption capacity of quercetin on the proposed imprinted cavity of rutin in the presence of glucose and rhamnose was 3.7 ± 0.017 times as much as that in the absence of glucose and rhamnose. And the adsorption capacity of quercetin varied with the conce...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - June 15, 2022 Category: Chemistry Authors: Hongying Cheng Jingqi Chen Xuan Liu Yifan Shen Qianli Zhang Source Type: research

A flower-like ionic molecularly imprinted membrane for the deglycosylation of rutin
Anal Sci. 2022 Jun 15. doi: 10.1007/s44211-022-00125-3. Online ahead of print.ABSTRACTA kind of molecularly imprinted polymer based on ionic liquids (MIPIL) with flower-like shape was developed for the adsorption of rutin and its deglycosylated product. The MIPIL film was characterized by scanning electron microscope (SEM) and X-ray photo-electron spectroscopy (XPS). The adsorption capacity of quercetin on the proposed imprinted cavity of rutin in the presence of glucose and rhamnose was 3.7 ± 0.017 times as much as that in the absence of glucose and rhamnose. And the adsorption capacity of quercetin varied with the conce...
Source: Anal Sci - June 15, 2022 Category: Chemistry Authors: Hongying Cheng Jingqi Chen Xuan Liu Yifan Shen Qianli Zhang Source Type: research

A flower-like ionic molecularly imprinted membrane for the deglycosylation of rutin
Anal Sci. 2022 Jun 15. doi: 10.1007/s44211-022-00125-3. Online ahead of print.ABSTRACTA kind of molecularly imprinted polymer based on ionic liquids (MIPIL) with flower-like shape was developed for the adsorption of rutin and its deglycosylated product. The MIPIL film was characterized by scanning electron microscope (SEM) and X-ray photo-electron spectroscopy (XPS). The adsorption capacity of quercetin on the proposed imprinted cavity of rutin in the presence of glucose and rhamnose was 3.7 ± 0.017 times as much as that in the absence of glucose and rhamnose. And the adsorption capacity of quercetin varied with the conce...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - June 15, 2022 Category: Chemistry Authors: Hongying Cheng Jingqi Chen Xuan Liu Yifan Shen Qianli Zhang Source Type: research

Ameliorative effects of phytomedicines on Alzheimer's patients
CONCLUSION: The present review is a comprehensive and up-to-date analysis supported with the evidentiary profs from pre-clinical studies, meta-analyses, and review papers related to natural phytochemicals' impact on neurodegenerative disorders like AD.PMID:35692129 | DOI:10.2174/1567205019666220610155608 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - June 13, 2022 Category: Neurology Authors: Rekha Khandia Neerja Viswanathan Shailja Singhal Taha Alqahtani Mohannad A Almikhlafi Alexander Nikolaevich Simonov Ghulam Md Ashraf Source Type: research

Adsorption properties and mechanism of ginkgo biloba leaf-based materials for Cd (II) in aqueous solution
In this study, three kinds of adsorbents, original ginkgo leaf (GL), NaOH modified ginkgo leaf (NaOH-GL), and KMnO4-modified ginkgo leaf (KMnO4-GL), were prepared and used to adsorb Cd (II) in aqueous solution respectively. The effects of the concentration of Cd (II), absorption time, the dosage of absorbent, and pH of solution on the adsorption process were explored by adsorption experiments. The results showed that the maximum adsorption capacity of Cd (II) by GL, NaOH-GL, and KMnO4-GL was 10.20 mg/g, 39.99 mg/g, and 48.82 mg/g, respectively, under the conditions of room temperature, adsorbent dosage 1g/L, adsorption tim...
Source: Environmental Science and Pollution Research International - June 13, 2022 Category: Environmental Health Authors: Yan-Rong Cai Yang Song Chun Chang Source Type: research

Ameliorative effects of phytomedicines on Alzheimer's patients
CONCLUSION: The present review is a comprehensive and up-to-date analysis supported with the evidentiary profs from pre-clinical studies, meta-analyses, and review papers related to natural phytochemicals' impact on neurodegenerative disorders like AD.PMID:35692129 | DOI:10.2174/1567205019666220610155608 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - June 13, 2022 Category: Neurology Authors: Rekha Khandia Neerja Viswanathan Shailja Singhal Taha Alqahtani Mohannad A Almikhlafi Alexander Nikolaevich Simonov Ghulam Md Ashraf Source Type: research

Ameliorative effects of phytomedicines on Alzheimer's patients
CONCLUSION: The present review is a comprehensive and up-to-date analysis supported with the evidentiary profs from pre-clinical studies, meta-analyses, and review papers related to natural phytochemicals' impact on neurodegenerative disorders like AD.PMID:35692129 | DOI:10.2174/1567205019666220610155608 (Source: Current Alzheimer Research)
Source: Current Alzheimer Research - June 13, 2022 Category: Neurology Authors: Rekha Khandia Neerja Viswanathan Shailja Singhal Taha Alqahtani Mohannad A Almikhlafi Alexander Nikolaevich Simonov Ghulam Md Ashraf Source Type: research

Ginkgo biloba extract mitigates the neurotoxicity of AlCl3 in alzheimer rat ’s model: role of apolipoprotein E4 and clusterin genes in stimulating ROS generation and apoptosis
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - June 9, 2022 Category: Neuroscience Authors: Ashwaq H. Batawi Source Type: research

Genes, Vol. 13, Pages 1036: The Roles of Mutation and Selection Acting on Mitochondrial Genomes Inferred from Intraspecific Variation in Seed Plants
This study reveals the intraspecific variation pattern of organelle genomes at a genome-wide level, and that copy number variations were common in plant mitochondrial genomes. (Source: Genes)
Source: Genes - June 9, 2022 Category: Genetics & Stem Cells Authors: Shenglong Kan Xuezhu Liao Zhiqiang Wu Tags: Article Source Type: research

Ginkgo Biloba Extract Ameliorates Scopolamine-induced Memory Deficits via Rescuing Synaptic Damage
ConclusionThe application of EGb effectively treats SCO-induced memory impairments probably by suppressing miR-1-3p/miR-206-3p and elevating the expression of PSD95. (Source: Journal of Huazhong University of Science and Technology -- Medical Sciences --)
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - June 8, 2022 Category: Research Source Type: research

Repetitive Elements, Sequence Turnover and Cyto-Nuclear Gene Transfer in Gymnosperm Mitogenomes
Among the three genomes in plant cells, the mitochondrial genome (mitogenome) is the least studied due to complex recombination and intergenomic transfer. In gymnosperms only ∼20 mitogenomes have been released thus far, which hinders a systematic investigation into the tempo and mode of mitochondrial DNA evolution in seed plants. Here, we report the complete mitogenome sequence of Platycladus orientalis (Cupressaceae). This mitogenome is assembled as two circular-mapping chromosomes with a size of ∼2.6 Mb and which contains 32 protein-coding genes, three rRNA and seven tRNA genes, and 1,068 RNA editing sites. Repetiti...
Source: Frontiers in Genetics - May 25, 2022 Category: Genetics & Stem Cells Source Type: research

Biflavonoids from Ginkgo biloba leaves as a novel anti-atherosclerotic candidate: Inhibition potency and mechanistic analysis
CONCLUSION: Among all four biflavonoids, ginkgetin significantly inhibited oleic acid-induced lipid production in HepG2 cells and reduced total cholesterol and triglyceride levels. The interaction of ginkgetin with CDK2 through π-alkyl and hydrogen bonds increased the binding of molecules and proteins. Ginkgetin arrested the cells in the G1-S phase, which significantly inhibited abnormal cell growth which closely related to the occurrence and development of atherosclerosis. Biflavonoids could be a promising natural medicine for the treatment of atherosclerosis.PMID:35567993 | DOI:10.1016/j.phymed.2022.154053 (Source: Atherosclerosis)
Source: Atherosclerosis - May 14, 2022 Category: Cardiology Authors: Li-Tao Wang Han Huang Yuan-Hang Chang Yan-Qiu Wang Jian-Dong Wang Zi-Hui Cai Thomas Efferth Yu-Jie Fu Source Type: research

The Anti-Parkinson Potential of Gingko biloba-Supplement Mitigates Cortico-Cerebellar Degeneration and Neuropathobiological Alterations via Inflammatory and Apoptotic Mediators in Mice
Neurochem Res. 2022 May 9. doi: 10.1007/s11064-022-03600-5. Online ahead of print.ABSTRACTActivation of nuclear factor erythroid 2 related factor 2 (Nrf2) associated with the suppression of various oxido-inflammatory pathways and the controller of several gene expressions involving "antioxidant response elements" (AREs) in their promoters to mediate and restores homeostatic functions is now considered as one of the main switch regulating the immune response, and it is also now involved in inflammatory cascade in PD. Whether therapeutic approach using Ginkgo biloba would have significant protective effects against cortico-c...
Source: Neurochemical Research - May 9, 2022 Category: Neuroscience Authors: Olusegun G Adebayo Wadioni Aduema Modo U Emmanuel Benneth Ben-Azu Blessing O Orji Ekam Akpakpan Oluwakemi Rachael Adebayo Ogechukwu G Onuoha Abayomi M Ajayi Source Type: research

The Anti-Parkinson Potential of Gingko biloba-Supplement Mitigates Cortico-Cerebellar Degeneration and Neuropathobiological Alterations via Inflammatory and Apoptotic Mediators in Mice
Neurochem Res. 2022 May 9. doi: 10.1007/s11064-022-03600-5. Online ahead of print.ABSTRACTActivation of nuclear factor erythroid 2 related factor 2 (Nrf2) associated with the suppression of various oxido-inflammatory pathways and the controller of several gene expressions involving "antioxidant response elements" (AREs) in their promoters to mediate and restores homeostatic functions is now considered as one of the main switch regulating the immune response, and it is also now involved in inflammatory cascade in PD. Whether therapeutic approach using Ginkgo biloba would have significant protective effects against cortico-c...
Source: Neurochemical Research - May 9, 2022 Category: Neuroscience Authors: Olusegun G Adebayo Wadioni Aduema Modo U Emmanuel Benneth Ben-Azu Blessing O Orji Ekam Akpakpan Oluwakemi Rachael Adebayo Ogechukwu G Onuoha Abayomi M Ajayi Source Type: research