Radioprotective effect of Ginkgolide B on brain: The mediating role of DCC/MST1 signaling
CONCLUSION: Oxidative stress and MST1-mediated neuronal apoptosis participated in radiation-induced cognitive impairment and depression-like behaviors, and modulation of DCC by GB was an effective intervention against RBI.PMID:37934907 | DOI:10.1080/09553002.2023.2281515 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - November 7, 2023 Category: Radiology Authors: Tao Yang Xiao Du Lixing Xu Source Type: research
Molecular docking analysis of acetylcholinesterase inhibitors for Alzheimer's disease management
This study suggests that further experimental investigations can be conducted on Ginkgolide A and Licorice glycoside D2 to explore their potential therapeutic applications for AD.PMID:37886145 | PMC:PMC10599677 | DOI:10.6026/97320630019565 (Source: Bioinformation)
Source: Bioinformation - October 27, 2023 Category: Bioinformatics Authors: Israa J Hakeem Source Type: research
Genome-wide identification of the Pinus tabuliformis CONSTANS-like gene family and their potential roles in reproductive cone development
Int J Biol Macromol. 2023 Oct 25:127621. doi: 10.1016/j.ijbiomac.2023.127621. Online ahead of print.ABSTRACTThe CONSTANS-like (COL) genes, as a core transcription factor in the photoperiod regulation pathway, play a key role in plant reproduction development. However, their molecular characterization has rarely been studied in Pinus tabuliformis. Here, 10 PtCOL genes were identified in the P. tabuliformis genome and multiple sequence alignments have indicated that the PtCOL proteins contained highly conserved B-BOX1 and CCT domains. Sequence similarity analysis showed that PtCOL1 and PtCOL3 had the higher similarity with N...
Source: International Journal of Biological Macromolecules - October 27, 2023 Category: Biochemistry Authors: Wenbin Yang Chengcheng Zhou Yingtian Guo Shihui Niu Yousry A El-Kassaby Wei Li Source Type: research
Molecular docking analysis of acetylcholinesterase inhibitors for Alzheimer's disease management
This study suggests that further experimental investigations can be conducted on Ginkgolide A and Licorice glycoside D2 to explore their potential therapeutic applications for AD.PMID:37886145 | PMC:PMC10599677 | DOI:10.6026/97320630019565 (Source: Bioinformation)
Source: Bioinformation - October 27, 2023 Category: Bioinformatics Authors: Israa J Hakeem Source Type: research
Molecular docking analysis of acetylcholinesterase inhibitors for Alzheimer's disease management
This study suggests that further experimental investigations can be conducted on Ginkgolide A and Licorice glycoside D2 to explore their potential therapeutic applications for AD.PMID:37886145 | PMC:PMC10599677 | DOI:10.6026/97320630019565 (Source: Bioinformation)
Source: Bioinformation - October 27, 2023 Category: Bioinformatics Authors: Israa J Hakeem Source Type: research
Modeling the Antiviral Activity of Ginkgo Biloba Polyphenols Against Variola: In Silico Exploration of Inhibitory Candidates for Vartmpk and Hsstmpk Enzymes
CONCLUSION: Based on the obtained scores and Lipinski's rules, Liquiritin, Olivil, and ginkgolic acids molecules showed interesting results for both studied enzymes, indicating the existence of promising and moderate activity of these polyphenols for the treatment of variola and for possible multi-targeting. Liquiritin has been shown to exhibit anti-inflammatory effects on various inflammation- related diseases such as skin injury, hepatic inflammatory injury, and rheumatoid arthritis. Olivil has been shown to have antioxidant activity. Olivil derivatives have also been studied for their potential use as anticancer agents....
Source: Current Drug Discovery Technologies - October 20, 2023 Category: Drugs & Pharmacology Authors: Sarra Hamdani Salim Bouchentouf Hocine Allali Source Type: research
Modeling the Antiviral Activity of Ginkgo Biloba Polyphenols Against Variola: In Silico Exploration of Inhibitory Candidates for Vartmpk and Hsstmpk Enzymes
CONCLUSION: Based on the obtained scores and Lipinski's rules, Liquiritin, Olivil, and ginkgolic acids molecules showed interesting results for both studied enzymes, indicating the existence of promising and moderate activity of these polyphenols for the treatment of variola and for possible multi-targeting. Liquiritin has been shown to exhibit anti-inflammatory effects on various inflammation- related diseases such as skin injury, hepatic inflammatory injury, and rheumatoid arthritis. Olivil has been shown to have antioxidant activity. Olivil derivatives have also been studied for their potential use as anticancer agents....
Source: Current Drug Discovery Technologies - October 20, 2023 Category: Drugs & Pharmacology Authors: Sarra Hamdani Salim Bouchentouf Hocine Allali Source Type: research
Modeling the Antiviral Activity of Ginkgo Biloba Polyphenols Against Variola: In Silico Exploration of Inhibitory Candidates for Vartmpk and Hsstmpk Enzymes
CONCLUSION: Based on the obtained scores and Lipinski's rules, Liquiritin, Olivil, and ginkgolic acids molecules showed interesting results for both studied enzymes, indicating the existence of promising and moderate activity of these polyphenols for the treatment of variola and for possible multi-targeting. Liquiritin has been shown to exhibit anti-inflammatory effects on various inflammation- related diseases such as skin injury, hepatic inflammatory injury, and rheumatoid arthritis. Olivil has been shown to have antioxidant activity. Olivil derivatives have also been studied for their potential use as anticancer agents....
Source: Current Drug Discovery Technologies - October 20, 2023 Category: Drugs & Pharmacology Authors: Sarra Hamdani Salim Bouchentouf Hocine Allali Source Type: research
Retracted: Efficacy of < em > Ginkgo biloba < /em > Extract Combined with Hormones in the Treatment of Sudden Deafness and Its Effect on the Reactivity of Peripheral Blood T Cell Subsets
Comput Math Methods Med. 2023 Oct 4;2023:9839531. doi: 10.1155/2023/9839531. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2022/2903808.].PMID:37829529 | PMC:PMC10567257 | DOI:10.1155/2023/9839531 (Source: Computational and Mathematical Methods in Medicine)
Source: Computational and Mathematical Methods in Medicine - October 13, 2023 Category: Statistics Authors: Computational And Mathematical Methods In Medicine Source Type: research
