Treatment methods for cervical intraepithelial neoplasia in England: A cost-effectiveness analysis
CONCLUSIONS: LLETZ is the most cost-effective treatment for both younger and older women. However, for older women, more radical excision with laser conisation could also be considered if the NHS is willing to spend more than £31,500 to avert one CIN2+ recurrence.PMID:38659133 | DOI:10.1111/1471-0528.17829 (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 25, 2024 Category: OBGYN Authors: Michela Tinelli Antonios Athanasiou Areti Angeliki Veroniki Orestis Efthimiou Ilkka Kalliala Sarah Bowden Maria Paraskevaidi Deirdre Lyons Pierre Martin-Hirsch Phillip Bennett Evangelos Paraskevaidis Georgia Salanti Maria Kyrgiou Huseyin Naci Source Type: research
Molecular epidemiology of HIV among people who inject drugs after the HIV-outbreak in Athens, Greece: Evidence for a 'slow burn' outbreak
CONCLUSIONS: The substantial proportion of clustered infections (93.5%) during 2016-2019 implies a persistent 'slow burn' HIV outbreak among PWID in Athens, suggesting that the outbreak was not successfully eliminated. The consistently high proportion of clustered sequences since the onset of the outbreak suggests the persistence of ongoing HIV-1 transmission attributed to injection practices. Our findings underscore the importance of targeted interventions among PWID, considering the ongoing transmission rate and prolonged time from infection to diagnosis.PMID:38663466 | DOI:10.1016/j.meegid.2024.105597 (Source: Infection...
Source: Infection, Genetics and Evolution - April 25, 2024 Category: Genetics & Stem Cells Authors: Evangelia Georgia Kostaki Sotirios Roussos Anastasia Maria Kefala Stefanos Limnaios Mina Psichogiou Eleni Papachristou Georgios Nikolopoulos Eleni Flountzi Samuel R Friedman Pagona Lagiou Angelos Hatzakis Vana Sypsa Gkikas Magiorkinis Apostolos Beloukas D Source Type: research
The association between neighborhood deprivation and DNA methylation in an autopsy cohort
Aging (Albany NY). 2024 Apr 24;16. doi: 10.18632/aging.205764. Online ahead of print.ABSTRACTPrevious research has found that living in a disadvantaged neighborhood is associated with poor health outcomes. Living in disadvantaged neighborhoods may alter inflammation and immune response in the body, which could be reflected in epigenetic mechanisms such as DNA methylation (DNAm). We used robust linear regression models to conduct an epigenome-wide association study examining the association between neighborhood deprivation (Area Deprivation Index; ADI), and DNAm in brain tissue from 159 donors enrolled in the Emory Goizueta...
Source: Aging - April 25, 2024 Category: Biomedical Science Authors: Lindsay Pett Zhenjiang Li Sarina Abrishamcar Kenyaita Hodge Todd Everson Grace Christensen Marla Gearing Michael S Kobor Chaini Konwar Julia L MacIsaac Kristy Dever Aliza P Wingo Allan Levey James J Lah Thomas S Wingo Anke H üls Source Type: research
Molecular epidemiology of HIV among people who inject drugs after the HIV-outbreak in Athens, Greece: Evidence for a 'slow burn' outbreak
CONCLUSIONS: The substantial proportion of clustered infections (93.5%) during 2016-2019 implies a persistent 'slow burn' HIV outbreak among PWID in Athens, suggesting that the outbreak was not successfully eliminated. The consistently high proportion of clustered sequences since the onset of the outbreak suggests the persistence of ongoing HIV-1 transmission attributed to injection practices. Our findings underscore the importance of targeted interventions among PWID, considering the ongoing transmission rate and prolonged time from infection to diagnosis.PMID:38663466 | DOI:10.1016/j.meegid.2024.105597 (Source: Infection...
Source: Infection, Genetics and Evolution - April 25, 2024 Category: Genetics & Stem Cells Authors: Evangelia Georgia Kostaki Sotirios Roussos Anastasia Maria Kefala Stefanos Limnaios Mina Psichogiou Eleni Papachristou Georgios Nikolopoulos Eleni Flountzi Samuel R Friedman Pagona Lagiou Angelos Hatzakis Vana Sypsa Gkikas Magiorkinis Apostolos Beloukas D Source Type: research
Molecular epidemiology of HIV among people who inject drugs after the HIV-outbreak in Athens, Greece: Evidence for a 'slow burn' outbreak
CONCLUSIONS: The substantial proportion of clustered infections (93.5%) during 2016-2019 implies a persistent 'slow burn' HIV outbreak among PWID in Athens, suggesting that the outbreak was not successfully eliminated. The consistently high proportion of clustered sequences since the onset of the outbreak suggests the persistence of ongoing HIV-1 transmission attributed to injection practices. Our findings underscore the importance of targeted interventions among PWID, considering the ongoing transmission rate and prolonged time from infection to diagnosis.PMID:38663466 | DOI:10.1016/j.meegid.2024.105597 (Source: Infection...
Source: Infection, Genetics and Evolution - April 25, 2024 Category: Genetics & Stem Cells Authors: Evangelia Georgia Kostaki Sotirios Roussos Anastasia Maria Kefala Stefanos Limnaios Mina Psichogiou Eleni Papachristou Georgios Nikolopoulos Eleni Flountzi Samuel R Friedman Pagona Lagiou Angelos Hatzakis Vana Sypsa Gkikas Magiorkinis Apostolos Beloukas D Source Type: research
Effects of maternal supplementation with DHA and/or egg yolk powder on monoamine homeostasis in the perinatal piglet brain
. (Source: Nutritional Neuroscience)
Source: Nutritional Neuroscience - April 25, 2024 Category: Nutrition Authors: Brice T. HudsonStephanie T. DubrofSkylar E. SettlesHea J. ParkNikolay M. Filipova Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA, USAb Department of Nutritional Sciences, College of Family and Source Type: research
Comparison of maternal venous blood metabolomics collected as dried blood spots, dried blood microsamplers, and plasma for integrative environmental health research
Environ Int. 2024 Apr 16;187:108663. doi: 10.1016/j.envint.2024.108663. Online ahead of print.ABSTRACTUse of capillary blood devices for exposome research can deepen our understanding of the intricate relationship between environment and health, and open up new avenues for preventive and personalized medicine, particularly for vulnerable populations. While the potential of these whole blood devices to accurately measure chemicals and metabolites has been demonstrated, how untargeted metabolomics data from these samplers can be integrated with previous and ongoing environmental health studies that have used conventional blo...
Source: Environment International - April 24, 2024 Category: Environmental Health Authors: Lauren Petrick Haibin Guan Grier P Page Georgia Dolios Megan M Niedzwiecki Robert O Wright Rosalind J Wright program collaborators for Environmental Influences on Child Health Outcomes Source Type: research
Comparison of maternal venous blood metabolomics collected as dried blood spots, dried blood microsamplers, and plasma for integrative environmental health research
Environ Int. 2024 Apr 16;187:108663. doi: 10.1016/j.envint.2024.108663. Online ahead of print.ABSTRACTUse of capillary blood devices for exposome research can deepen our understanding of the intricate relationship between environment and health, and open up new avenues for preventive and personalized medicine, particularly for vulnerable populations. While the potential of these whole blood devices to accurately measure chemicals and metabolites has been demonstrated, how untargeted metabolomics data from these samplers can be integrated with previous and ongoing environmental health studies that have used conventional blo...
Source: Environment International - April 24, 2024 Category: Environmental Health Authors: Lauren Petrick Haibin Guan Grier P Page Georgia Dolios Megan M Niedzwiecki Robert O Wright Rosalind J Wright program collaborators for Environmental Influences on Child Health Outcomes Source Type: research
The effect of obesity and subsequent weight reduction on cardiac morphology and function in cats
In people, obesity is a risk factor for cardiovascular disease, associated with systemic hypertension, cardiac remodelling and systolic and diastolic dysfunction. Weight reduction can reverse myocardial remode... (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - April 24, 2024 Category: Veterinary Research Authors: Catheryn Partington, Hannah Hodgkiss-Geere, Georgia R. T. Woods, Joanna Dukes-McEwan, John Flanagan, Vincent Biourge and Alexander J. German Tags: Research Source Type: research
Histological reappraisal of IgA nephropathy: the role of glomerular pattern of injury and mesangial complement deposition
There is a clear need to refine the histological assessment in IgA Nephropathy (IgAN). We sought to investigate the clinical significance of the light microscopy (LM) pattern of glomerular injury and of the in... (Source: BMC Nephrology)
Source: BMC Nephrology - April 24, 2024 Category: Urology & Nephrology Authors: Bogdan Obri șcă, Valentin Mocanu, Roxana Jurubiță, Alexandra Vrabie, Andreea Berechet, Ștefan Lujinschi, Bogdan Sorohan, Andreea Andronesi, Camelia Achim, Gabriela Lupușoru, Georgia Micu, Nicu Caceaune, Mihaela Gherghiceanu and Gener Ismail Tags: Research Source Type: research
The perception and passage of time during public speaking
Acta Psychol (Amst). 2024 Apr 22;246:104268. doi: 10.1016/j.actpsy.2024.104268. Online ahead of print.ABSTRACTSeveral studies have shown that anxious individuals experience a slower passage of time under threat conditioning. Anxiety-evoking situations have also been proposed to elevate arousal levels, which, in turn, alter one's time percept. However, the effect of social stressors on time perception remains significantly neglected. The current research aimed to investigate the impact of anxiety levels on time estimation and passage of time judgments during public speaking in healthy adults. Participants were recruited fro...
Source: Acta Psychologica - April 23, 2024 Category: Psychiatry & Psychology Authors: Efthymia Lamprou Georgia Koupriza Argiro Vatakis Source Type: research
A mixed-methods study of women's birthplace preferences and decisions in England
CONCLUSION: Women navigate complex and competing discourses when forming childbirth preferences and making decisions, selectively considering different risks and knowledges to make the decisions right for them.PMID:38653144 | DOI:10.1016/j.wombi.2024.101616 (Source: Women Birth)
Source: Women Birth - April 23, 2024 Category: Midwifery Authors: Georgia E Clancy Felicity K Boardman Sophie Rees Source Type: research
The perception and passage of time during public speaking
Acta Psychol (Amst). 2024 Apr 22;246:104268. doi: 10.1016/j.actpsy.2024.104268. Online ahead of print.ABSTRACTSeveral studies have shown that anxious individuals experience a slower passage of time under threat conditioning. Anxiety-evoking situations have also been proposed to elevate arousal levels, which, in turn, alter one's time percept. However, the effect of social stressors on time perception remains significantly neglected. The current research aimed to investigate the impact of anxiety levels on time estimation and passage of time judgments during public speaking in healthy adults. Participants were recruited fro...
Source: Acta Psychologica - April 23, 2024 Category: Psychiatry & Psychology Authors: Efthymia Lamprou Georgia Koupriza Argiro Vatakis Source Type: research
A mixed-methods study of women's birthplace preferences and decisions in England
CONCLUSION: Women navigate complex and competing discourses when forming childbirth preferences and making decisions, selectively considering different risks and knowledges to make the decisions right for them.PMID:38653144 | DOI:10.1016/j.wombi.2024.101616 (Source: Women Birth)
Source: Women Birth - April 23, 2024 Category: Midwifery Authors: Georgia E Clancy Felicity K Boardman Sophie Rees Source Type: research
The perception and passage of time during public speaking
Acta Psychol (Amst). 2024 Apr 22;246:104268. doi: 10.1016/j.actpsy.2024.104268. Online ahead of print.ABSTRACTSeveral studies have shown that anxious individuals experience a slower passage of time under threat conditioning. Anxiety-evoking situations have also been proposed to elevate arousal levels, which, in turn, alter one's time percept. However, the effect of social stressors on time perception remains significantly neglected. The current research aimed to investigate the impact of anxiety levels on time estimation and passage of time judgments during public speaking in healthy adults. Participants were recruited fro...
Source: Acta Psychologica - April 23, 2024 Category: Psychiatry & Psychology Authors: Efthymia Lamprou Georgia Koupriza Argiro Vatakis Source Type: research
