Viruses, Vol. 16, Pages 376: Deletion of the EP402R Gene from the Genome of African Swine Fever Vaccine Strain ASFV-G- & #8710;I177L Provides the Potential Capability of Differentiating between Infected and Vaccinated Animals
In this report, we describe the development of the ASFV-G-∆I177L mutant having deleted the EP402R gene, which encodes for the viral protein responsible for mediating the hemadsorption of swine erythrocytes. The resulting virus, ASFV-G-∆I177L/∆EP402R, does not have a decreased ability to replicates in swine macrophages when compared with the parental ASFV-G-∆I177L. Domestic pigs intramuscularly (IM) inoculated with either 102 or 106 HAD50 of ASFV-G-∆I177L/∆EP402R remained clinically normal, when compared with a group of mock-vaccinated anima...
Source: Viruses - February 28, 2024 Category: Virology Authors: Manuel V. Borca Elizabeth Ramirez-Medina Nallely Espinoza Ayushi Rai Edward Spinard Lauro Velazquez-Salinas Alyssa Valladares Ediane Silva Leeanna Burton Amanda Meyers Jason Clark Ping Wu Cyril G. Gay Douglas P. Gladue Tags: Article Source Type: research
Disparities in sleep care and cardiovascular outcomes: defining the problem and implementing solutions
Journal of Clinical Sleep Medicine, Ahead of Print. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - February 28, 2024 Category: Sleep Medicine Authors: William J. Healy
Dayna A. Johnson
Xiaoyue Liu
Girardin Jean-Louis
Younghoon Kwon
1Division of Pulmonary, Critical Care, and Sleep Medicine; Medical College of Georgia at Augusta University, Augusta, GA
2Department of Epidemiology, Rollins School of Public Source Type: research
