This tiny swimming robot can think for itself
MINNEAPOLIS— Tiny robots that swim through our blood to deliver drugs or hunt down pathogens have been a staple of science fiction for decades. Although still distant, that vision is a step closer to reality now that electrical engineers have unveiled swimming microrobots smaller than grains of sand with enough computing power to perform a simple task on their own—rather than being constantly guided by external signals. “It’s awesome,” says Daniel Goldman, a physicist at the Georgia Institute of Technology who specializes in larger robots that mimic animals. He was not involved in the work, which was ...
Source: Science of Aging Knowledge Environment - March 7, 2024 Category: Geriatrics Source Type: research

Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 < sup > + < /sup > T cell responses
Sci Adv. 2024 Mar 8;10(10):eadl1122. doi: 10.1126/sciadv.adl1122. Epub 2024 Mar 6.ABSTRACTCoxsackievirus B (CVB) infection of pancreatic β cells is associated with β cell autoimmunity and type 1 diabetes. We investigated how CVB affects human β cells and anti-CVB T cell responses. β cells were efficiently infected by CVB in vitro, down-regulated human leukocyte antigen (HLA) class I, and presented few, selected HLA-bound viral peptides. Circulating CD8+ T cells from CVB-seropositive individuals recognized a fraction of these peptides; only another subfraction was targeted by effector/memory T cells that expressed exhau...
Source: Adv Data - March 6, 2024 Category: Epidemiology Authors: Federica Vecchio Alexia Carr é Daniil Korenkov Zhicheng Zhou Paola Apaolaza Soile Tuomela Orlando Burgos-Morales Isaac Snowhite Javier Perez-Hernandez Barbara Brandao Georgia Afonso Cl émentine Halliez John Kaddis Sally C Kent Maki Nakayama Sarah J Rich Source Type: research

Social uncertainty in the digital world
We present a computational framework for thinking about how increasingly popular online environments modulate the social uncertainty we experience, depending on the type of social inferences we make. This framework draws on Bayesian inference, which involves combining multiple informational sources to update our beliefs.PMID:38448356 | DOI:10.1016/j.tics.2024.02.005 (Source: Trends Cogn Sci)
Source: Trends Cogn Sci - March 6, 2024 Category: Neuroscience Authors: Amanda M Ferguson Georgia Turner Amy Orben Source Type: research

The detailed histopathological characteristics of ovarian fibroma compared with thecoma, granulosa cell tumor, and sclerosing stromal tumor
CONCLUSION: Ovarian fibromas can present some maybe unexpected features rather frequently, such as cystic degeneration, hyaline plaques, prominent vascularity, increased cellularity, and some mitotic activity, thus their presence should not always prompt to an alternative diagnosis.PMID:38447489 | DOI:10.1016/j.prp.2024.155236 (Source: Cell Research)
Source: Cell Research - March 6, 2024 Category: Cytology Authors: Mousa Mobarki Alexandra Papoudou-Bai Shaqraa Musawi Michel P éoc'h Georgia Karpathiou Source Type: research

Impact of Implementation Facilitation on the REACH VET Clinical Program for Veterans at Risk for Suicide
CONCLUSIONS: Facilitation of REACH VET implementation was associated with an improvement in outreach attempts to veterans identified as being at increased risk for suicide. Outreach is critical for engaging veterans in care.PMID:38444365 | DOI:10.1176/appi.ps.20230277 (Source: Psychiatric Services)
Source: Psychiatric Services - March 6, 2024 Category: Psychiatry Authors: Sara J Landes Bridget B Matarazzo Jeffery A Pitcock Karen L Drummond Brandy N Smith JoAnn E Kirchner Kaily A Clark Georgia R Gerard Molly C Jankovsky Lisa A Brenner Mark A Reger Aaron E Eagan Rebecca Raciborski Jacob Painter James C Townsend Susan M Jegle Source Type: research

The detailed histopathological characteristics of ovarian fibroma compared with thecoma, granulosa cell tumor, and sclerosing stromal tumor
CONCLUSION: Ovarian fibromas can present some maybe unexpected features rather frequently, such as cystic degeneration, hyaline plaques, prominent vascularity, increased cellularity, and some mitotic activity, thus their presence should not always prompt to an alternative diagnosis.PMID:38447489 | DOI:10.1016/j.prp.2024.155236 (Source: Pathology, Research and Practice)
Source: Pathology, Research and Practice - March 6, 2024 Category: Pathology Authors: Mousa Mobarki Alexandra Papoudou-Bai Shaqraa Musawi Michel P éoc'h Georgia Karpathiou Source Type: research

Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 < sup > + < /sup > T cell responses
Sci Adv. 2024 Mar 8;10(10):eadl1122. doi: 10.1126/sciadv.adl1122. Epub 2024 Mar 6.ABSTRACTCoxsackievirus B (CVB) infection of pancreatic β cells is associated with β cell autoimmunity and type 1 diabetes. We investigated how CVB affects human β cells and anti-CVB T cell responses. β cells were efficiently infected by CVB in vitro, down-regulated human leukocyte antigen (HLA) class I, and presented few, selected HLA-bound viral peptides. Circulating CD8+ T cells from CVB-seropositive individuals recognized a fraction of these peptides; only another subfraction was targeted by effector/memory T cells that expressed exhau...
Source: Adv Data - March 6, 2024 Category: Epidemiology Authors: Federica Vecchio Alexia Carr é Daniil Korenkov Zhicheng Zhou Paola Apaolaza Soile Tuomela Orlando Burgos-Morales Isaac Snowhite Javier Perez-Hernandez Barbara Brandao Georgia Afonso Cl émentine Halliez John Kaddis Sally C Kent Maki Nakayama Sarah J Rich Source Type: research

Social uncertainty in the digital world
We present a computational framework for thinking about how increasingly popular online environments modulate the social uncertainty we experience, depending on the type of social inferences we make. This framework draws on Bayesian inference, which involves combining multiple informational sources to update our beliefs.PMID:38448356 | DOI:10.1016/j.tics.2024.02.005 (Source: Trends Cogn Sci)
Source: Trends Cogn Sci - March 6, 2024 Category: Neuroscience Authors: Amanda M Ferguson Georgia Turner Amy Orben Source Type: research

Impact of Implementation Facilitation on the REACH VET Clinical Program for Veterans at Risk for Suicide
CONCLUSIONS: Facilitation of REACH VET implementation was associated with an improvement in outreach attempts to veterans identified as being at increased risk for suicide. Outreach is critical for engaging veterans in care.PMID:38444365 | DOI:10.1176/appi.ps.20230277 (Source: Psychiatric Services)
Source: Psychiatric Services - March 6, 2024 Category: Psychiatry Authors: Sara J Landes Bridget B Matarazzo Jeffery A Pitcock Karen L Drummond Brandy N Smith JoAnn E Kirchner Kaily A Clark Georgia R Gerard Molly C Jankovsky Lisa A Brenner Mark A Reger Aaron E Eagan Rebecca Raciborski Jacob Painter James C Townsend Susan M Jegle Source Type: research

Social uncertainty in the digital world
We present a computational framework for thinking about how increasingly popular online environments modulate the social uncertainty we experience, depending on the type of social inferences we make. This framework draws on Bayesian inference, which involves combining multiple informational sources to update our beliefs.PMID:38448356 | DOI:10.1016/j.tics.2024.02.005 (Source: Trends Cogn Sci)
Source: Trends Cogn Sci - March 6, 2024 Category: Neuroscience Authors: Amanda M Ferguson Georgia Turner Amy Orben Source Type: research

Impact of Implementation Facilitation on the REACH VET Clinical Program for Veterans at Risk for Suicide
CONCLUSIONS: Facilitation of REACH VET implementation was associated with an improvement in outreach attempts to veterans identified as being at increased risk for suicide. Outreach is critical for engaging veterans in care.PMID:38444365 | DOI:10.1176/appi.ps.20230277 (Source: Psychiatric Services)
Source: Psychiatric Services - March 6, 2024 Category: Psychiatry Authors: Sara J Landes Bridget B Matarazzo Jeffery A Pitcock Karen L Drummond Brandy N Smith JoAnn E Kirchner Kaily A Clark Georgia R Gerard Molly C Jankovsky Lisa A Brenner Mark A Reger Aaron E Eagan Rebecca Raciborski Jacob Painter James C Townsend Susan M Jegle Source Type: research

Social uncertainty in the digital world
We present a computational framework for thinking about how increasingly popular online environments modulate the social uncertainty we experience, depending on the type of social inferences we make. This framework draws on Bayesian inference, which involves combining multiple informational sources to update our beliefs.PMID:38448356 | DOI:10.1016/j.tics.2024.02.005 (Source: Trends Cogn Sci)
Source: Trends Cogn Sci - March 6, 2024 Category: Neuroscience Authors: Amanda M Ferguson Georgia Turner Amy Orben Source Type: research

Impact of Implementation Facilitation on the REACH VET Clinical Program for Veterans at Risk for Suicide
CONCLUSIONS: Facilitation of REACH VET implementation was associated with an improvement in outreach attempts to veterans identified as being at increased risk for suicide. Outreach is critical for engaging veterans in care.PMID:38444365 | DOI:10.1176/appi.ps.20230277 (Source: Psychiatric Services)
Source: Psychiatric Services - March 6, 2024 Category: Psychiatry Authors: Sara J Landes Bridget B Matarazzo Jeffery A Pitcock Karen L Drummond Brandy N Smith JoAnn E Kirchner Kaily A Clark Georgia R Gerard Molly C Jankovsky Lisa A Brenner Mark A Reger Aaron E Eagan Rebecca Raciborski Jacob Painter James C Townsend Susan M Jegle Source Type: research

Social uncertainty in the digital world
We present a computational framework for thinking about how increasingly popular online environments modulate the social uncertainty we experience, depending on the type of social inferences we make. This framework draws on Bayesian inference, which involves combining multiple informational sources to update our beliefs.PMID:38448356 | DOI:10.1016/j.tics.2024.02.005 (Source: Trends Cogn Sci)
Source: Trends Cogn Sci - March 6, 2024 Category: Neuroscience Authors: Amanda M Ferguson Georgia Turner Amy Orben Source Type: research

Impact of Implementation Facilitation on the REACH VET Clinical Program for Veterans at Risk for Suicide
CONCLUSIONS: Facilitation of REACH VET implementation was associated with an improvement in outreach attempts to veterans identified as being at increased risk for suicide. Outreach is critical for engaging veterans in care.PMID:38444365 | DOI:10.1176/appi.ps.20230277 (Source: Psychiatric Services)
Source: Psychiatric Services - March 6, 2024 Category: Psychiatry Authors: Sara J Landes Bridget B Matarazzo Jeffery A Pitcock Karen L Drummond Brandy N Smith JoAnn E Kirchner Kaily A Clark Georgia R Gerard Molly C Jankovsky Lisa A Brenner Mark A Reger Aaron E Eagan Rebecca Raciborski Jacob Painter James C Townsend Susan M Jegle Source Type: research