Correction: Implementation of the Diabetes Prevention Program in Georgia Cooperative Extension According to RE-AIM and the Consolidated Framework for Implementation Research
(Source: Prevention Science)
Source: Prevention Science - March 15, 2024 Category: Psychiatry & Psychology Source Type: research
The immune microenvironment of cancer of the uterine cervix
Histol Histopathol. 2024 Mar 1:18727. doi: 10.14670/HH-18-727. Online ahead of print.ABSTRACTWhile several treatment choices exist for cervical cancer, such as surgical therapy, chemotherapy, and radiotherapy, some patients will still show poor prognosis. HPV infection is a principal factor for cervical cancer development, from early inflammation to proliferation, angiogenesis, and neoplastic growth. While HPV T-cell responses exist, the tumor seems to evade the immune system upon its tolerance. The latter suggests the existence of a confluent tumor microenvironment responsible for the evasion tactics employed by the neopl...
Source: Histology and Histopathology - March 14, 2024 Category: Cytology Authors: Michail Mastrogeorgiou Elena Chatzikalil Stamatios Theocharis Alexandra Papoudou-Bai Michel P éoc'h Mousa Mobarki Georgia Karpathiou Source Type: research
Artificial intelligence in medicine: mitigating risks and maximizing benefits via quality assurance, quality control, and acceptance testing
BJR Artif Intell. 2024 Mar 4;1(1):ubae003. doi: 10.1093/bjrai/ubae003. eCollection 2024 Jan.ABSTRACTThe adoption of artificial intelligence (AI) tools in medicine poses challenges to existing clinical workflows. This commentary discusses the necessity of context-specific quality assurance (QA), emphasizing the need for robust QA measures with quality control (QC) procedures that encompass (1) acceptance testing (AT) before clinical use, (2) continuous QC monitoring, and (3) adequate user training. The discussion also covers essential components of AT and QA, illustrated with real-world examples. We also highlight what we s...
Source: Cancer Control - March 13, 2024 Category: Cancer & Oncology Authors: Usman Mahmood Amita Shukla-Dave Heang-Ping Chan Karen Drukker Ravi K Samala Quan Chen Daniel Vergara Hayit Greenspan Nicholas Petrick Berkman Sahiner Zhimin Huo Ronald M Summers Kenny H Cha Georgia Tourassi Thomas M Deserno Kevin T Grizzard Janne J N äpp Source Type: research
Circadian patterns of behaviour change during pregnancy in mice
In conclusion, increased food intake during pregnancy reflects increased amplitude of eating behaviour, without longer duration. Decreases in activity also contribute to positive energy balance in pregnancy, with delays to all measured behaviours evident from mid-pregnancy onwards. KEY POINTS: Circadian rhythms synchronise daily behaviours including eating, drinking and sleep, but how these change in pregnancy is unclear. Food intake increased, with delays in peaks of food intake behaviour late in the light phase from days 6.5 to 12.5 of pregnancy, in comparison to the non-pregnant group. The onset of activity after lights...
Source: The Journal of Physiology - March 13, 2024 Category: Physiology Authors: Georgia S Clarke Andrew D Vincent Sharon R Ladyman Kathryn L Gatford Amanda J Page Source Type: research
Drug-Resistant Tuberculosis, Georgia, Kazakhstan, Kyrgyzstan, Moldova, and Ukraine, 2017 –2022
V. Dahl et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - March 12, 2024 Category: Infectious Diseases Source Type: research
Assessment of the Quality, Accountability, and Readability of Online Patient Education Materials for Optic Neuritis
. (Source: Neuro-Ophthalmology)
Source: Neuro-Ophthalmology - March 12, 2024 Category: Opthalmology Authors: Prem N. PatelParth A. PatelHarris AhmedKevin E. LaiDevin D. MackaySusan P. MollanMelanie Truong-Lea Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas, USAb Department of Ophthalmology, Medical College of Georgia, Source Type: research
Cost-effectiveness analysis of minimally invasive surgical treatments for benign prostatic hyperplasia: implications for Japan's public healthcare system
CONCLUSIONS: Driven by lower retreatment and AE rates, WAVE was a cost-effective and cost-saving treatment for moderate-to-severe BPH in Japan compared to PUL, providing better outcomes at lower costs to the healthcare system.PMID:38466193 | DOI:10.1080/13696998.2024.2327920 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - March 11, 2024 Category: Health Management Authors: Hisataka Anezaki Fumiyasu Endo Georgia Swan Kenta Takashima Sirikan Rojanasarot Source Type: research
Exploring type I interferon pathway: virulent vs. attenuated strain of African swine fever virus revealing a novel function carried by MGF505-4R
African swine fever virus represents a significant reemerging threat to livestock populations, as its incidence and geographic distribution have surged over the past decade in Europe, Asia, and Caribbean, resulting in substantial socio-economic burdens and adverse effects on animal health and welfare. In a previous report, we described the protective properties of our newly thermo-attenuated strain (ASFV-989) in pigs against an experimental infection of its parental Georgia 2007/1 virulent strain. In this new study, our objective was to characterize the molecular mechanisms underlying the attenuation of ASFV-989. We first ...
Source: Frontiers in Immunology - March 11, 2024 Category: Allergy & Immunology Source Type: research
Centring participant experience: a realist evaluation of a menstruator-friendly facility design project in a refugee settlement, Lebanon
Menstrual health in humanitarian contexts is a neglected topic. Its taboo nature presents difficulties for participants in menstrual health projects in these particularly challenging settings. Namely, their ex... (Source: BMC Women's Health)
Source: BMC Women's Health - March 9, 2024 Category: OBGYN Authors: Georgia Hales, Paul Hutchings, Katy Roelich, Mahua Das, Alexandra Machado, Debora Bonucci and Farah Salem Tags: Research Source Type: research
Viruses, Vol. 16, Pages 417: Single MVA-SARS-2-ST/N Vaccination Rapidly Protects K18-hACE2 Mice against a Lethal SARS-CoV-2 Challenge Infection
In this study, we developed a recombinant MVA vaccine co-expressing SARS-CoV-2 prefusion-stabilized spike protein (ST) and SARS-CoV-2 nucleoprotein (N, MVA-SARS-2-ST/N) as an approach to further improve vaccine-induced immunogenicity and efficacy. Single MVA-SARS-2-ST/N vaccination in K18-hACE2 mice induced robust protection against lethal respiratory SARS-CoV-2 challenge infection 28 days later. The protective outcome of MVA-SARS-2-ST/N vaccination correlated with the activation of SARS-CoV-2-neutralizing antibodies (nABs) and substantial amounts of SARS-CoV-2-specific T cells especially in the lung of MVA-SARS-2-ST/N-vac...
Source: Viruses - March 8, 2024 Category: Virology Authors: Sabrina Clever Leonard Limpinsel Christian Meyer zu Natrup Lisa-Marie Sch ünemann Georg Beythien Malgorzata Rosiak Kirsten H ülskötter Katharina Manuela Gregor Tamara Tuchel Georgia Kalodimou Astrid Freudenstein Satendra Kumar Wolfgang Baumg ärtner Ge Tags: Article Source Type: research
This tiny swimming robot can think for itself
MINNEAPOLIS—
Tiny robots that swim through our blood to deliver drugs or hunt down pathogens have been a staple of science fiction for decades. Although still distant, that vision is a step closer to reality now that electrical engineers have unveiled swimming microrobots smaller than grains of sand with enough computing power to perform a simple task on their own—rather than being constantly guided by external signals.
“It’s awesome,” says Daniel Goldman, a physicist at the Georgia Institute of Technology who specializes in larger robots that mimic animals. He was not involved in the work, which was
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Source: Science of Aging Knowledge Environment - March 7, 2024 Category: Geriatrics Source Type: research
