Generalized Anxiety Disorder (GAD) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Impact of Prior COVID-19 Infections on Cardiac Rehabilitation Completion Rates and Outcomes
CONCLUSIONS: Having a prior COVID-19 infection did not negatively impact the mental and physical health benefits obtained by completing the CR program, regardless of the American Association of Cardiovascular and Pulmonary Rehabilitation risk category.PMID:38669342 | DOI:10.1097/HCR.0000000000000841 (Source: Journal of Cardiopulmonary Rehabilitation and Prevention)
Source: Journal of Cardiopulmonary Rehabilitation and Prevention - April 26, 2024 Category: Rehabilitation Authors: Matthew A Taylor Julia L Berkowitz Kevin Chen Julianne DeAngelis Wen-Chih Wu Source Type: research

IJERPH, Vol. 21, Pages 545: The Relationship between Anxiety Symptoms and Perceived Quality of Life among Caregivers of Children with Autism Spectrum Disorder in the Amazon
Gomes The relationship between anxiety symptoms and perceived quality of life among caregivers of children with autism was verified. To assess perceived quality of life, the Short Form Healthy Survey Item was used; perception of anxiety symptoms was assessed using the Beck Anxiety Inventory. Eighty caregivers of children with autism participated, with 68.7% of caregivers being mothers. Of the total number of caregivers, 68.8% had a severe level of anxiety. Regarding perceived quality of life, they demonstrated greater impairment in limitation due to physical aspects, limitation due to emotional aspects, vitality, and p...
Source: International Journal of Environmental Research and Public Health - April 26, 2024 Category: Environmental Health Authors: Rayanne Vieira da Silva Manuela Maria de Lima Carvalhal Daniela Lopes Gomes Tags: Article Source Type: research

Problematic Online Behaviours among University Students and Associations with Psychological Distress Symptoms and Emotional Role Limitations: A Network Analysis Approach
AbstractVery little research has simultaneously explored the interactions between generalized problematic internet use (GPIU), problematic social media use (PSMU), problematic online gaming (POG), psychological distress, and emotional well-being among university students. Therefore, the present study aimed to determine (i) the associations between GPIU, PSMU, and POG symptoms, (ii) whether symptoms of these three problematic online behaviours form distinct entities, and (iii) whether there are associations between problematic online behaviours, psychological distress symptoms, and emotional role limitations using network a...
Source: International Journal of Mental Health and Addiction - April 26, 2024 Category: Addiction Source Type: research

PBPK modeling to predict the pharmacokinetics of venlafaxine and its active metabolite in different CYP2D6 genotypes and drug-drug interactions with clarithromycin and paroxetine
This study aimed to establish the PBPK models of venlafaxine and its active metabolite related to CYP2D6 genetic polymorphism and to predict drug-drug interactions (DDIs) with clarithromycin and paroxetine in different CYP2D6 genotypes. Clinical pharmacogenomic data for venlafaxine and desvenlafaxine were collected to build the PBPK model. Physicochemical and absorption, distribution, metabolism, and excretion (ADME) characteristics of respective compounds were obtained from previously reported data, predicted by the PK-Sim® software, or optimized to capture the plasma concentration-time profiles. Model evaluation was per...
Source: Archives of Pharmacal Research - April 25, 2024 Category: Drugs & Pharmacology Authors: Chang-Keun Cho Pureum Kang Choon-Gon Jang Seok-Yong Lee Yun Jeong Lee Jung-Woo Bae Chang-Ik Choi Source Type: research

Mapping functions for the PHQ-9 and GAD-7 to generate EQ-5D-3L for economic evaluation
ConclusionsRecommended mapping functions provide users with an approach to estimate EQ-5D-3L utilities for economic evaluation using PHQ-9, GAD-7, or both scores where they have been used together. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - April 25, 2024 Category: Health Management Source Type: research

Screening for those at risk for anxiety and depression warranting further clinical evaluation among patients presenting to breast services: a single-centre, cross-sectional study
Conclusions There is a high prevalence of being at risk for anxiety and depression among patients who seek breast services warranting further clinical evaluation. The predictors of being at risk for anxiety were higher age and postmenopausal status, and for those at risk for depression were young age and residing in rural areas. (Source: BMJ Open)
Source: BMJ Open - April 25, 2024 Category: General Medicine Authors: Husain, S., Rao, S., Suresh, S., Jesudoss, K. V. A., Krishna, B., Raj, J. P. Tags: Open access, Surgery Source Type: research

Lifetime prevalence, comorbidities, and Sociodemographic predictors of post-traumatic stress disorder (PTSD): the National Epidemiology of Iranian Children and adolescents Psychiatric disorders (IRCAP)
Conclusion: Our results in the prevalence, comorbidities, and sociodemographic factors associated with PTSD supported findings of previous studies that used a structured diagnostic interview. It is recommended to use purposive sampling and to investigate comorbidities of PTSD and type of traumatic events in a large clinical population. (Source: European Child and Adolescent Psychiatry)
Source: European Child and Adolescent Psychiatry - April 24, 2024 Category: Psychiatry Source Type: research

Analyzing the Quality of Life in Individuals with Fragile X Syndrome in Relation to Sleep and Mental Health
This study included 119 individuals with Fragile X Syndrome who were given different cognitive examinations by a neuropsychologist or by parent-proxy questionnaires. This study focused on the Pediatric Quality of Life Inventory (PedsQoL), the Anxiety, Depression and Mood Scale (ADAMS), the Children's Sleep Habits Questionnaire (CSHQ), but did include other cognitive tests (Vineland Adaptive Behaviour Scales, Nonverbal IQ, Autism Diagnostic Observation Schedule). We identified significant associations between decreases in emotional, social and school domains of PedsQoL and the ADAMS subtests of Generalized Anxiety, Manic/Hy...
Source: Journal of Autism and Developmental Disorders - April 23, 2024 Category: Psychiatry Authors: Amrita Minhas Kerri Whitlock Cory Rosenfelt Julie Shatto Brittany Finlay Jennifer Zwicker Sarah Lippe Sebastien Jacquemont Randi Hagerman Kara Murias Francois V Bolduc Source Type: research

Network analysis of the comorbidity between post-traumatic stress, depression and anxiety symptoms among frontline healthcare workers during the COVID-19 pandemic
CONCLUSION: Our data suggest mild level of PTSS, depression and anxiety symptoms among HCWs during the pandemic and might give novel insights into assessment and intervention of comorbidity.PMID:38644941 | PMC:PMC11032008 | DOI:10.1177/20451253241243292 (Source: Adv Data)
Source: Adv Data - April 22, 2024 Category: Epidemiology Authors: Hui Ouyang Lili Wu Wenjie Yan Keyi Si Hongli Lv Jingye Zhan Jing Wang Yanpu Jia Zhilei Shang Wenfang Chen Weizhi Liu Source Type: research

Newer Treatments for Mood and Anxiety Disorders
For more than 20 years, the mainstay of pharmacologic treatment for depression and anxiety disorders has been serotonin reuptake inhibitors and selective serotonin and norepinephrine reuptake inhibitors. There are newer medications, many with novel mechanisms of action, that have come to market; however, first-lin e treatments remain the same. There are now more robust data on the use of various augmentation agents in the treatment of major depressive disorder providing better recommendations for use by the primary care provider. Data to support the use of psychedelic-assisted psychotherapy in the treatment o f mood and ...
Source: Medical Clinics of North America - April 21, 2024 Category: Primary Care Authors: Jesse Markman, Heidi Combs Source Type: research

Validation of the Chinese version of the Fear of Birth Scale among pregnant women
CONCLUSION: The FOBS-C exhibits robust psychometric properties, making it a valid screening tool for identifying severe fear of birth. Establishing a cutoff point at 65 facilitates effective screening.PMID:38642425 | DOI:10.1016/j.midw.2024.103986 (Source: Midwifery)
Source: Midwifery - April 20, 2024 Category: Midwifery Authors: Qianmin Zhang Judith McAra-Couper Yi Lou Shengbin Guo Pingping Qiu Source Type: research

Grey matter alterations in generalized anxiety disorder: A voxel-wise meta-analysis of voxel-based morphometry studies
CONCLUSION: GAD might have the modest grey matter alterations in the left superior temporal gyrus. Anxiety severity might be related to the grey matter alterations in the limbic regions, such as the right insula, lenticular nucleus, putamen and striatum. This kind of correlation might be related to the effects of adult GAD. Future studies with adequate sample sizes and sophisticated GAD categories will be needed.PMID:38638086 | DOI:10.1002/jdn.10330 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - April 19, 2024 Category: Neuroscience Authors: Chang-Hsien Ou Chiu-Shih Cheng Pei-Ling Lin Cheng-Lung Lee Source Type: research