Digital Gangrene Associated with Scrub Typhus: A Case Series
We report three cases of scrub fever (55-year-old female, 63-year-old female, and 29-year-old male), all cases developed focal or pan-digital gangrene. All cases were successfully treated by administering doxycycline and additional supportive measures. Digital gangrene is uncommon in scrub typhus. Clinical suspension for early diagnosis and appropriate treatment may avoid further complications.PMID:38350131 | DOI:10.4269/ajtmh.23-0596 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - February 13, 2024 Category: Tropical Medicine Authors: Jitendra Singh Anju Dinkar Nilesh Kumar Kailash Kumar Nidhi Tejan Source Type: research
Digital Gangrene Associated with Scrub Typhus: A Case Series
We report three cases of scrub fever (55-year-old female, 63-year-old female, and 29-year-old male), all cases developed focal or pan-digital gangrene. All cases were successfully treated by administering doxycycline and additional supportive measures. Digital gangrene is uncommon in scrub typhus. Clinical suspension for early diagnosis and appropriate treatment may avoid further complications.PMID:38350131 | DOI:10.4269/ajtmh.23-0596 (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - February 13, 2024 Category: Infectious Diseases Authors: Jitendra Singh Anju Dinkar Nilesh Kumar Kailash Kumar Nidhi Tejan Source Type: research
Symmetrical peripheral gangrene following testicular torsion surgery: A case report
Key Clinical MessageSymmetrical peripheral gangrene (SPG) is very rare condition associated with symmetrical ischemia and gangrene affecting two or more distal extremities. It is almost always associated with septicemia and has a high mortality rate. The rarity of this condition and lack of prospective trials makes its recognition and management difficult. Care providers should maintain a high index of suspicion for SPG in patients with sepsis who develop cyanosis and ischemia of extremities. Doing early culture and sensitivity studies is key in guiding apropriate antibiotic treatment.AbstractSymmetrical peripheral gangren...
Source: Clinical Case Reports - February 9, 2024 Category: General Medicine Authors: Kamoga Dickson,
Kato Ronald Tags: CASE REPORT Source Type: research
Digital gangrene in systemic sclerosis patients: not only due to the microvascular disease
ConclusionSmoking history; positive-ACA, ANCA, and anti-phospholipid antibodies; and increased ESR were independent risk factors for digital gangrenes in SSc. Vasculitis and macrovascular disease may contribute to the progression of digital gangrenes.Key Points•18.6% of SSc patients with digital gangrene had macrovascular stenosis.•Smoking, positive-ACA, ANCA, aPL, and increased ESR were indicators for digital gangrenes in SSc.•Vasculitis and macrovascular disease may involve in the pathogenesis. (Source: Clinical Rheumatology)
Source: Clinical Rheumatology - February 2, 2024 Category: Rheumatology Source Type: research
PACE: randomized, controlled, multicentre, multinational, phase III study of PLX-PAD for critical limb ischaemia in patients unsuitable for revascularization: randomized clinical trial
CONCLUSION: Although there was no evidence that PLX-PAD reduced amputation-free survival in the entire study population, benefit was observed in patients without diabetes mellitus or whose diabetes was well controlled; this requires confirmation in further studies. Trial registration: NCT03006770 (http://www.clinicaltrials.gov); 2015-005532-18 (EudraCT Clinical Trials register - Search for 2015-005532-18).PMID:38294084 | PMC:PMC10828925 | DOI:10.1093/bjs/znad437 (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - January 31, 2024 Category: Surgery Authors: Lars Norgren Norbert Weiss Sigrid Nikol John C Lantis Manesh R Patel Robert J Hinchliffe Holger Reinecke Hans Dieter Volk Petra Reinke Gian Paolo Fadini Racheli Ofir Daniel Rothenstein Nitsan Halevy Mitko Karagjozov John H Rundback Source Type: research
The Association of Telangiectasias with Other Peripheral Vascular Lesions of Systemic Sclerosis
CONCLUSION: We appreciate that telangiectasias may be the clinical expression of peripheral vasculopathy characteristic of SSc, they can often be present in association with other peripheral vascular lesions and may represent a valuable indicator for the gangrene risk of digital ulcerations in SSc.PMID:38292323 | PMC:PMC10826706 | DOI:10.2147/CCID.S432422 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - January 31, 2024 Category: Dermatology Authors: Carmen Bobeica Elena Niculet Carmina Liana Musat Lina Iancu Mihaela Craescu Andreea Mioara Luca Bogdan Ioan Stefanescu Emma Gheorghe Mihaela Debita Claudiu-Ionut Vasile Gabriela Balan Camelia Busila Alin Laurentiu Tatu Source Type: research
Maternal Strangulated Diaphragmatic Hernia with Gangrene of the Entire Stomach During Pregnancy: A Case Report and Review of the Recent Literature [Response to Letter]
(Source: International Journal of Womens Health)
Source: International Journal of Womens Health - January 31, 2024 Category: OBGYN Tags: International Journal of Women's Health Source Type: research
A New Case of Fournier's Gangrene Caused by Actinotignum schaalii
In conclusion, it is thought that a significant proportion of A.schaalii infections may be overlooked due to the difficulty in growth and identification. Increasing the diagnostic power of clinical microbiology laboratories for poorly identified bacteria and renewing the databases of commercial identification systems are important for the early and accurate diagnosis and treatment of serious infections that may occur with such agents.PMID:38263943 | DOI:10.5578/mb.20249908 (Source: Mikrobiyoloji Bulteni)
Source: Mikrobiyoloji Bulteni - January 24, 2024 Category: Microbiology Authors: Hanife Tutan Cemil Kutsal Özlem Gül Elif Seren Tanr ıverdi Ay şe Barış Mehmet Emin Bulut Elif Akta ş Source Type: research
Leptospirosis Associated Digital Gangrene of Lower Extremities: Two Cases and Review of Literature
CONCLUSION: Apart from a high index of suspicion and awareness of unusual manifestations, serology plays a vital role in making an accurate and quick diagnosis to initiate appropriate therapy.PMID:38265373 | DOI:10.2174/0118715265256882231128074609 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - January 24, 2024 Category: Infectious Diseases Authors: Anju Dinkar Jitendra Singh Mahima Yadav Source Type: research
A New Case of Fournier's Gangrene Caused by Actinotignum schaalii
In conclusion, it is thought that a significant proportion of A.schaalii infections may be overlooked due to the difficulty in growth and identification. Increasing the diagnostic power of clinical microbiology laboratories for poorly identified bacteria and renewing the databases of commercial identification systems are important for the early and accurate diagnosis and treatment of serious infections that may occur with such agents.PMID:38263943 | DOI:10.5578/mb.20249908 (Source: Mikrobiyoloji Bulteni)
Source: Mikrobiyoloji Bulteni - January 24, 2024 Category: Microbiology Authors: Hanife Tutan Cemil Kutsal Özlem Gül Elif Seren Tanr ıverdi Ay şe Barış Mehmet Emin Bulut Elif Akta ş Source Type: research
