National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma
World J Gastroenterol. 2024 Mar 7;30(9):1018-1042. doi: 10.3748/wjg.v30.i9.1018.ABSTRACTA consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26, 2023, at the Pakistan Kidney and Liver Institute & Research Centre (PKLI & RC) after initial consultations with the experts. The Pakistan Society for the Study of Liver Diseases (PSSLD) and PKLI & RC jointly organised this meeting. This effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma (hCCA). The consensus was that hCCA is a comple...
Source: World Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Authors: Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Source Type: research
National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma
World J Gastroenterol. 2024 Mar 7;30(9):1018-1042. doi: 10.3748/wjg.v30.i9.1018.ABSTRACTA consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26, 2023, at the Pakistan Kidney and Liver Institute & Research Centre (PKLI & RC) after initial consultations with the experts. The Pakistan Society for the Study of Liver Diseases (PSSLD) and PKLI & RC jointly organised this meeting. This effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma (hCCA). The consensus was that hCCA is a comple...
Source: World Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Authors: Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Source Type: research
National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma
World J Gastroenterol. 2024 Mar 7;30(9):1018-1042. doi: 10.3748/wjg.v30.i9.1018.ABSTRACTA consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26, 2023, at the Pakistan Kidney and Liver Institute & Research Centre (PKLI & RC) after initial consultations with the experts. The Pakistan Society for the Study of Liver Diseases (PSSLD) and PKLI & RC jointly organised this meeting. This effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma (hCCA). The consensus was that hCCA is a comple...
Source: World Journal of Gastroenterology - April 5, 2024 Category: Gastroenterology Authors: Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Source Type: research
National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma
World J Gastroenterol. 2024 Mar 7;30(9):1018-1042. doi: 10.3748/wjg.v30.i9.1018.ABSTRACTA consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26, 2023, at the Pakistan Kidney and Liver Institute & Research Centre (PKLI & RC) after initial consultations with the experts. The Pakistan Society for the Study of Liver Diseases (PSSLD) and PKLI & RC jointly organised this meeting. This effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma (hCCA). The consensus was that hCCA is a comple...
Source: World Journal of Gastroenterology : WJG - April 5, 2024 Category: Gastroenterology Authors: Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Source Type: research
Diffuse large B-cell lymphoma with DNA copy number changes in a Japanese black calf
AbstractA 2-month-old Japanese Black calf exhibited mandibular and superficial cervical lymph node swelling. Fine needle aspiration cytology of the superficial cervical lymph node revealed large lymphoblast-like cells with mitoses. Hematological examination revealed remarkable lymphocytosis with atypical lymphocytes. Increased activities of serum total lactate dehydrogenase and thymidine kinase were detected. At necropsy, generalized swelling of lymph nodes was observed. Histopathological analysis revealed diffuse proliferation of medium-sized round centroblastic neoplastic cells that were positive for CD20, CD79 α, PAX5,...
Source: Veterinary Research Communications - April 5, 2024 Category: Veterinary Research Source Type: research
Sensors, Vol. 24, Pages 2312: Advancing Breast Cancer Diagnosis through Breast Mass Images, Machine Learning, and Regression Models
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Breast cancer results from a disruption of certain cells in breast tissue that undergo uncontrolled growth and cell division. These cells most often accumulate and form a lump called a tumor, which may be benign (non-cancerous) or malignant (cancerous). Malignant tumors can spread quickly throughout the body, forming tumors in other areas, which is called metastasis. Standard screening techniques are insufficient in the case of metastasis; therefore, new and advanced techniques based on artificial intelligence (AI), machine learning, and regression models have been introduced, the primary aim of which is to automat...
Source: Sensors - April 5, 2024 Category: Biotechnology Authors: Amira J. Zaylaa Sylva Kourtian Tags: Article Source Type: research
Diffuse large B-cell lymphoma with DNA copy number changes in a Japanese black calf
Vet Res Commun. 2024 Apr 5. doi: 10.1007/s11259-024-10371-7. Online ahead of print.ABSTRACTA 2-month-old Japanese Black calf exhibited mandibular and superficial cervical lymph node swelling. Fine needle aspiration cytology of the superficial cervical lymph node revealed large lymphoblast-like cells with mitoses. Hematological examination revealed remarkable lymphocytosis with atypical lymphocytes. Increased activities of serum total lactate dehydrogenase and thymidine kinase were detected. At necropsy, generalized swelling of lymph nodes was observed. Histopathological analysis revealed diffuse proliferation of medium-siz...
Source: Cell Research - April 4, 2024 Category: Cytology Authors: Masaki Maezawa Ken-Ichi Watanabe Yoshiyasu Kobayashi Kio Yoshida James K Chambers Kazuyuki Uchida Reo Maruyama Hisashi Inokuma Source Type: research
Diffuse large B-cell lymphoma with DNA copy number changes in a Japanese black calf
Vet Res Commun. 2024 Apr 5. doi: 10.1007/s11259-024-10371-7. Online ahead of print.ABSTRACTA 2-month-old Japanese Black calf exhibited mandibular and superficial cervical lymph node swelling. Fine needle aspiration cytology of the superficial cervical lymph node revealed large lymphoblast-like cells with mitoses. Hematological examination revealed remarkable lymphocytosis with atypical lymphocytes. Increased activities of serum total lactate dehydrogenase and thymidine kinase were detected. At necropsy, generalized swelling of lymph nodes was observed. Histopathological analysis revealed diffuse proliferation of medium-siz...
Source: Cell Research - April 4, 2024 Category: Cytology Authors: Masaki Maezawa Ken-Ichi Watanabe Yoshiyasu Kobayashi Kio Yoshida James K Chambers Kazuyuki Uchida Reo Maruyama Hisashi Inokuma Source Type: research
The utility of endobronchial ultrasound ‐guided transbronchial mediastinal cryobiopsy (EBUS‐TBMC) for the diagnosis of mediastinal lymphoma
We present a gentleman with anterior mediastinal mass who underwent EBUS-transbronchial needle aspirate (TBNA) followed by EBUS-TBMC. TBMC samples provided adequate tissue to attain a diagnosis of primary mediastinal large B-cell lymphoma. AbstractEndobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a revolutionary tool for the diagnosis and staging of mediastinal disorders. Nevertheless, its diagnostic capability is reduced in certain disorders such as lymphoproliferative diseases. EBUS-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) is a novel technique that can provide larger samples ...
Source: Respirology Case Reports - April 4, 2024 Category: Respiratory Medicine Authors: Nai ‐Chien Huan,
Wei Lun Lee,
Hema Yamini Ramarmuty,
Larry Ellee Nyanti,
Melody Shu Ling Tsen,
Dahziela Yunus Tags: CASE REPORT Source Type: research
A vocal cord palsy caused by the uterine cancer metastatic tumor in the mediastinum revealed in a patient with a thyroid lesion: a case report and review of the literature
ConclusionA history of the disease should always be kept in mind when assessing a patient ’s complaints. VCP in case of thyroid pathology and previous secondary malignancy may be caused by metastatic tumor anywhere along the RLN pathway. Such a rare case shows the importance of additional methods of examination which may avoid unnecessary thyroid surgeries. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - April 4, 2024 Category: General Medicine Source Type: research
51 Percutaneous tissue sampling in thoracic oncology - are core biopsies bigger and better?
Small biopsies are the predominant source of tissue diagnosis in thoracic malignancy. As more tissue is required for expanding range of targets, should core biopsies replace fine-needle aspiration to ensure delivering enough material for diagnosis? (Source: Lung Cancer)
Source: Lung Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Hassan Maged, Fahd Irshad Tags: Diagnosis and Staging Source Type: research
40 A Retrospective Performance Audit of the West Yorkshire and Harrogate Cancer Alliance's EBUS-TBNA Service
We present the first performance audit of EBUS-TBNA services by the West Yorkshire and Harrogate Cancer Alliance (WYHCA), against the 2019 National Service Specification1. (Source: Lung Cancer)
Source: Lung Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Thomas Wilkins, LiJi Ng, Sara Upperton, Stephen Zwolinsky, Georgina Esterbrook, Ali Almeri, Sanjay Kumar, Leanne Cheyne Tags: Diagnosis and Staging Source Type: research
39 A multi-centre analysis of the performance of EBUS-TBNA testing for comprehensive molecular profiling in non-small cell lung cancer (NSCLC)
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an important diagnostic tool in lung cancer. Since 2021, the National Optimal Pathway for Lung Cancer in Wales has mandated reflex testing, using Next Generation Sequencing (NGS) for all stage non-small cell lung cancer in line with ESMO recommendations. The utilisation of NGS technologies in EBUS-TBNA specimens has been questioned, especially relating to the volume of tissue needed for successful DNA and RNA analysis. (Source: Lung Cancer)
Source: Lung Cancer - April 1, 2024 Category: Cancer & Oncology Authors: Craig Dyer, Kelly Marshall, Robin Ghosal, Rhian Williams Tags: Diagnosis and Staging Source Type: research
The role of fine-needle aspiration biopsy in the diagnosis of malignant tumors
Rom J Morphol Embryol. 2024 Jan-Mar;65(1):81-87. doi: 10.47162/RJME.65.1.10.ABSTRACTCytopathology and histopathology play a key role in the process of diagnosing oncological diseases and premalignant conditions. Fine-needle aspiration (FNA) is one of the techniques used for obtaining biopsy of a wide variety of body tissues, causing patients minimal discomfort. Therefore, it is often considered to be the best strategy for investigating and diagnosing some precancerous or potential malignant lesions. Being successful as a means of confirming the clinical suspicion of metastatic recurrence in the cases of an already known ca...
Source: Romanian Journal of Morphology and Embryology - March 26, 2024 Category: General Medicine Authors: Marius Rus Mircea Ioachim Popescu Ioana Adrian Ardelean Felicia Liana Andronie-Cioar ă Mihaela Gabriela Bon ţea R ăzvan Marius Vicaş Iulia Denisa Bogdan Source Type: research
