Characterization of postoperative LASIK ectasia features on higher-order aberration excimer ablation maps
To characterize anterior corneal higher-order aberration (HOA) excimer ablation map patterns in postoperative LASIK ectasia (POE) and to examine correlations between newly identified corneal HOA ablation map f... (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - December 20, 2023 Category: Opthalmology Authors: Avi Wallerstein, Sangeetha Santhakumaran, Lauren Tabunar, Mark Cohen and Mathieu Gauvin Tags: Research Source Type: research

Long-term cenobamate retention, efficacy, and safety: outcomes from Expanded Access Programme
CONCLUSIONS AND CLINICAL IMPLICATIONS: Long-term effectiveness, including ≥ 50% seizure reduction and a 100% retention rate, was sustained over 41 months of CNB treatment within the Expanded Access Programme. No new safety issues were identified. These results provide support for the potential long-term clinical benefits of cenobamate.PMID:38112647 | DOI:10.5603/pjnns.97121 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Anetta Lasek-Bal Barbara K ściuk Tomasz Zieli ński Agnieszka Krzak-Kubica Jacek Kowalski Barbara Żorniak-Milach Katarzyna Maciejowska Maciej Maciejowski Anna Wagner-Kusz Magdalena Bosak Source Type: research

Long-term cenobamate retention, efficacy, and safety: outcomes from Expanded Access Programme
CONCLUSIONS AND CLINICAL IMPLICATIONS: Long-term effectiveness, including ≥ 50% seizure reduction and a 100% retention rate, was sustained over 41 months of CNB treatment within the Expanded Access Programme. No new safety issues were identified. These results provide support for the potential long-term clinical benefits of cenobamate.PMID:38112647 | DOI:10.5603/pjnns.97121 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Anetta Lasek-Bal Barbara K ściuk Tomasz Zieli ński Agnieszka Krzak-Kubica Jacek Kowalski Barbara Żorniak-Milach Katarzyna Maciejowska Maciej Maciejowski Anna Wagner-Kusz Magdalena Bosak Source Type: research

Long-term cenobamate retention, efficacy, and safety: outcomes from Expanded Access Programme
CONCLUSIONS AND CLINICAL IMPLICATIONS: Long-term effectiveness, including ≥ 50% seizure reduction and a 100% retention rate, was sustained over 41 months of CNB treatment within the Expanded Access Programme. No new safety issues were identified. These results provide support for the potential long-term clinical benefits of cenobamate.PMID:38112647 | DOI:10.5603/pjnns.97121 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Anetta Lasek-Bal Barbara K ściuk Tomasz Zieli ński Agnieszka Krzak-Kubica Jacek Kowalski Barbara Żorniak-Milach Katarzyna Maciejowska Maciej Maciejowski Anna Wagner-Kusz Magdalena Bosak Source Type: research

Long-term cenobamate retention, efficacy, and safety: outcomes from Expanded Access Programme
CONCLUSIONS AND CLINICAL IMPLICATIONS: Long-term effectiveness, including ≥ 50% seizure reduction and a 100% retention rate, was sustained over 41 months of CNB treatment within the Expanded Access Programme. No new safety issues were identified. These results provide support for the potential long-term clinical benefits of cenobamate.PMID:38112647 | DOI:10.5603/pjnns.97121 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Anetta Lasek-Bal Barbara K ściuk Tomasz Zieli ński Agnieszka Krzak-Kubica Jacek Kowalski Barbara Żorniak-Milach Katarzyna Maciejowska Maciej Maciejowski Anna Wagner-Kusz Magdalena Bosak Source Type: research

Long-term cenobamate retention, efficacy, and safety: outcomes from Expanded Access Programme
CONCLUSIONS AND CLINICAL IMPLICATIONS: Long-term effectiveness, including ≥ 50% seizure reduction and a 100% retention rate, was sustained over 41 months of CNB treatment within the Expanded Access Programme. No new safety issues were identified. These results provide support for the potential long-term clinical benefits of cenobamate.PMID:38112647 | DOI:10.5603/pjnns.97121 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Anetta Lasek-Bal Barbara K ściuk Tomasz Zieli ński Agnieszka Krzak-Kubica Jacek Kowalski Barbara Żorniak-Milach Katarzyna Maciejowska Maciej Maciejowski Anna Wagner-Kusz Magdalena Bosak Source Type: research

Long-term cenobamate retention, efficacy, and safety: outcomes from Expanded Access Programme
CONCLUSIONS AND CLINICAL IMPLICATIONS: Long-term effectiveness, including ≥ 50% seizure reduction and a 100% retention rate, was sustained over 41 months of CNB treatment within the Expanded Access Programme. No new safety issues were identified. These results provide support for the potential long-term clinical benefits of cenobamate.PMID:38112647 | DOI:10.5603/pjnns.97121 (Source: Neurologia i Neurochirurgia Polska)
Source: Neurologia i Neurochirurgia Polska - December 19, 2023 Category: Neurology Authors: Anetta Lasek-Bal Barbara K ściuk Tomasz Zieli ński Agnieszka Krzak-Kubica Jacek Kowalski Barbara Żorniak-Milach Katarzyna Maciejowska Maciej Maciejowski Anna Wagner-Kusz Magdalena Bosak Source Type: research

Topical ocular administration using thermosensitive chitosan-glycerophosphate-PRP hydrogels for improved ocular bioavailability
CONCLUSIONS: Given this, CS-GP-based hydrogels can be applied as a biocompatible formulation in ocular medication administration with increased bioavailability at the ocular surface and topical delivery of PRP.PMID:38070308 | DOI:10.1016/j.bpc.2023.107141 (Source: Biophysical Chemistry)
Source: Biophysical Chemistry - December 9, 2023 Category: Chemistry Authors: Mohadeseh Rostamipoor Alireza Farsinejad Mahnaz Amiri Ahmad Fatemi Samira Anvari Source Type: research

Topical ocular administration using thermosensitive chitosan-glycerophosphate-PRP hydrogels for improved ocular bioavailability
CONCLUSIONS: Given this, CS-GP-based hydrogels can be applied as a biocompatible formulation in ocular medication administration with increased bioavailability at the ocular surface and topical delivery of PRP.PMID:38070308 | DOI:10.1016/j.bpc.2023.107141 (Source: Biophysical Chemistry)
Source: Biophysical Chemistry - December 9, 2023 Category: Chemistry Authors: Mohadeseh Rostamipoor Alireza Farsinejad Mahnaz Amiri Ahmad Fatemi Samira Anvari Source Type: research

Topical ocular administration using thermosensitive chitosan-glycerophosphate-PRP hydrogels for improved ocular bioavailability
CONCLUSIONS: Given this, CS-GP-based hydrogels can be applied as a biocompatible formulation in ocular medication administration with increased bioavailability at the ocular surface and topical delivery of PRP.PMID:38070308 | DOI:10.1016/j.bpc.2023.107141 (Source: Biophysical Chemistry)
Source: Biophysical Chemistry - December 9, 2023 Category: Chemistry Authors: Mohadeseh Rostamipoor Alireza Farsinejad Mahnaz Amiri Ahmad Fatemi Samira Anvari Source Type: research

Moisture chamber goggles for the treatment of postoperative dry eye in patients receiving SMILE and FS-LASIK surgery
The incidence of refractive surgery-related dry eye disease (DED) is rising due to the increasing popularity of corneal refractive surgery. The moisture chamber goggles (MCGs) have been shown to tear evaporati... (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - December 8, 2023 Category: Opthalmology Authors: Tianze Huang, Yuchen Wang, Zhou Zhu, Qingyang Wu, Di Chen and Ying Li Tags: Research Source Type: research

Differences in change of post-operative antioxidant levels between laser-assisted lenticule extraction and femtosecond laser in  situ keratomileusis
J Cell Mol Med. 2023 Dec 5. doi: 10.1111/jcmm.18069. Online ahead of print.ABSTRACTTo evaluate the change of total antioxidant capacity (TAC) and ascorbic acid (AA) between femtosecond laser in situ keratomileusis (FS-LASIK) and laser-assisted lenticule extraction (LALEX). A prospective non-randomized study was conducted, and 33 and 75 eyes that had undergone FS-LASIK or LALEX surgeries were enrolled, respectively. The tear films near corneal incisions were collected, and the concentrations of TAC and AA were determined. The generalized linear mixed model was adopted to calculate the adjusted odds ratio (aOR) with 95% conf...
Source: J Cell Mol Med - December 5, 2023 Category: Molecular Biology Authors: Hung-Chi Chen Shun-Fa Yang Chia-Yi Lee Yi-Jen Hsueh Jing-Yang Huang Chao-Kai Chang Source Type: research

Differences in change of post-operative antioxidant levels between laser-assisted lenticule extraction and femtosecond laser in  situ keratomileusis
J Cell Mol Med. 2023 Dec 5. doi: 10.1111/jcmm.18069. Online ahead of print.ABSTRACTTo evaluate the change of total antioxidant capacity (TAC) and ascorbic acid (AA) between femtosecond laser in situ keratomileusis (FS-LASIK) and laser-assisted lenticule extraction (LALEX). A prospective non-randomized study was conducted, and 33 and 75 eyes that had undergone FS-LASIK or LALEX surgeries were enrolled, respectively. The tear films near corneal incisions were collected, and the concentrations of TAC and AA were determined. The generalized linear mixed model was adopted to calculate the adjusted odds ratio (aOR) with 95% conf...
Source: Molecular Medicine - December 5, 2023 Category: Molecular Biology Authors: Hung-Chi Chen Shun-Fa Yang Chia-Yi Lee Yi-Jen Hsueh Jing-Yang Huang Chao-Kai Chang Source Type: research

Differences in change of post-operative antioxidant levels between laser-assisted lenticule extraction and femtosecond laser in  situ keratomileusis
J Cell Mol Med. 2023 Dec 5. doi: 10.1111/jcmm.18069. Online ahead of print.ABSTRACTTo evaluate the change of total antioxidant capacity (TAC) and ascorbic acid (AA) between femtosecond laser in situ keratomileusis (FS-LASIK) and laser-assisted lenticule extraction (LALEX). A prospective non-randomized study was conducted, and 33 and 75 eyes that had undergone FS-LASIK or LALEX surgeries were enrolled, respectively. The tear films near corneal incisions were collected, and the concentrations of TAC and AA were determined. The generalized linear mixed model was adopted to calculate the adjusted odds ratio (aOR) with 95% conf...
Source: J Cell Mol Med - December 5, 2023 Category: Molecular Biology Authors: Hung-Chi Chen Shun-Fa Yang Chia-Yi Lee Yi-Jen Hsueh Jing-Yang Huang Chao-Kai Chang Source Type: research

Rationale and design of a randomized clinical trial evaluating the efficacy of mechanical neuroprotection in reducing the risk of silent brain infarcts associated with percutaneous left atrial appendage closure: study protocol for a LAAC-SBI trial
Left atrial appendage closure (LAAC) procedures prevent cardioembolic stroke in patients with atrial fibrillation who have contraindications to oral anticoagulant medications. However, these procedures carry c... (Source: Trials)
Source: Trials - November 23, 2023 Category: General Medicine Authors: Witold Streb, Anetta Lasek-Bal, Katarzyna Mitr ęga, Jacek Kowalczyk, Tomasz Podolecki, Wiktoria Kowalska, Anna Olma, Agata Sobczyk and Zbigniew Kalarus Tags: Study protocol Source Type: research