Resveratrol increases tear production and ocular pain after corneal abrasion in male, but not female, rats using a photorefractive keratectomy model
We describe a preclinical corneal abrasion rat model that simulates the initial stages of PRK surgery and demonstrates similar pain and tear dysfunction as seen clinically. We used both behavioral and homeostatic assays to determine the therapeutic potential of resveratrol on pain and tear production. Studies were conducted in male and female Sprague-Dawley rats. Heptanol was applied to one eye and the superficial corneal epithelium was removed, mimicking the abrasion used in PRK. Spontaneous pain was assessed with orbital tightening (OT) scores for 7 days. Topical resveratrol increased OT scores sex-specifically in abrade...
Source: Experimental Eye Research - October 20, 2022 Category: Opthalmology Authors: Deborah M Hegarty James R Carroll Dennis Nguyen Victoria S Halls Dennis I Robbins Theodore J Price Gregory Dussor Sue A Aicher Source Type: research
Resveratrol increases tear production and ocular pain after corneal abrasion in male, but not female, rats using a photorefractive keratectomy model
We describe a preclinical corneal abrasion rat model that simulates the initial stages of PRK surgery and demonstrates similar pain and tear dysfunction as seen clinically. We used both behavioral and homeostatic assays to determine the therapeutic potential of resveratrol on pain and tear production. Studies were conducted in male and female Sprague-Dawley rats. Heptanol was applied to one eye and the superficial corneal epithelium was removed, mimicking the abrasion used in PRK. Spontaneous pain was assessed with orbital tightening (OT) scores for 7 days. Topical resveratrol increased OT scores sex-specifically in abrade...
Source: Experimental Eye Research - October 20, 2022 Category: Opthalmology Authors: Deborah M Hegarty James R Carroll Dennis Nguyen Victoria S Halls Dennis I Robbins Theodore J Price Gregory Dussor Sue A Aicher Source Type: research
Resveratrol increases tear production and ocular pain after corneal abrasion in male, but not female, rats using a photorefractive keratectomy model
We describe a preclinical corneal abrasion rat model that simulates the initial stages of PRK surgery and demonstrates similar pain and tear dysfunction as seen clinically. We used both behavioral and homeostatic assays to determine the therapeutic potential of resveratrol on pain and tear production. Studies were conducted in male and female Sprague-Dawley rats. Heptanol was applied to one eye and the superficial corneal epithelium was removed, mimicking the abrasion used in PRK. Spontaneous pain was assessed with orbital tightening (OT) scores for 7 days. Topical resveratrol increased OT scores sex-specifically in abrade...
Source: Experimental Eye Research - October 20, 2022 Category: Opthalmology Authors: Deborah M Hegarty James R Carroll Dennis Nguyen Victoria S Halls Dennis I Robbins Theodore J Price Gregory Dussor Sue A Aicher Source Type: research
Comparison of different correction formulas and measurement methods for the accurate determination of intraocular pressure after SMILE and FS-LASIK surgery
To compare the accuracy of non-contact tonometry, Pentacam, and corneal visualization Scheimpflug technology (Corvis ST) for the measurement of intraocular pressure (IOP) after small incision lenticule extract... (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - October 10, 2022 Category: Opthalmology Authors: Zhiqing Yang, Na Miao, Lixiang Wang and Ke Ma Tags: Research Source Type: research
Diffuse lamellar keratitis as a rare complication of diamond burr superficial keratectomy for recurrent corneal erosion: a case report
To present a case with a history of laser in situ keratomileusis (LASIK) developing diffuse lamellar keratitis (DLK) after diamond burr superficial keratectomy (DBSK) for recurrent corneal erosion (RCE). (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - September 7, 2022 Category: Opthalmology Authors: Hung-Yu Lin and Wei-Ting Ho Tags: Case report Source Type: research
Improving Patient Communication on LASIK Benefits and Risks
In an effort to ensure that the benefits and risks of laser-assisted in situ keratomileusis (LASIK) are clearly communicated to patients, the FDA has drafted guidance detailing proposed recommendations for the content and format of patient labeling for LASIK devices, according to an agency statement. The nonbinding draft is open for comment through October 26. (Source: JAMA)
Source: JAMA - September 6, 2022 Category: General Medicine Source Type: research
Corneal Biomechanics Losses Caused by Refractive Surgery
Curr Eye Res. 2022 Aug 24:1-7. doi: 10.1080/02713683.2022.2103569. Online ahead of print.ABSTRACTRecent advances, specifically in the understanding of the biomechanical properties of the cornea and its response to diseases and surgical interventions, have significantly improved the safety and surgical outcomes of corneal refractive surgery, whose popularity and demand continue to grow worldwide. However, iatrogenic keratectasia resulting from the deterioration in corneal biomechanics caused by surgical interventions, although rare, remains a global concern. On one hand, in vivo biomechanical evaluation, enabled by clinical...
Source: Current Eye Research - August 24, 2022 Category: Opthalmology Authors: FangJun Bao Bernardo T Lopes XiaoBo Zheng YuXin Ji JunJie Wang Ahmed Elsheikh Source Type: research
Corneal Biomechanics Losses Caused by Refractive Surgery
Curr Eye Res. 2022 Aug 24:1-7. doi: 10.1080/02713683.2022.2103569. Online ahead of print.ABSTRACTRecent advances, specifically in the understanding of the biomechanical properties of the cornea and its response to diseases and surgical interventions, have significantly improved the safety and surgical outcomes of corneal refractive surgery, whose popularity and demand continue to grow worldwide. However, iatrogenic keratectasia resulting from the deterioration in corneal biomechanics caused by surgical interventions, although rare, remains a global concern. On one hand, in vivo biomechanical evaluation, enabled by clinical...
Source: Current Eye Research - August 24, 2022 Category: Opthalmology Authors: FangJun Bao Bernardo T Lopes XiaoBo Zheng YuXin Ji JunJie Wang Ahmed Elsheikh Source Type: research
Corneal Biomechanics Losses Caused by Refractive Surgery
Curr Eye Res. 2022 Aug 24:1-7. doi: 10.1080/02713683.2022.2103569. Online ahead of print.ABSTRACTRecent advances, specifically in the understanding of the biomechanical properties of the cornea and its response to diseases and surgical interventions, have significantly improved the safety and surgical outcomes of corneal refractive surgery, whose popularity and demand continue to grow worldwide. However, iatrogenic keratectasia resulting from the deterioration in corneal biomechanics caused by surgical interventions, although rare, remains a global concern. On one hand, in vivo biomechanical evaluation, enabled by clinical...
Source: Current Eye Research - August 24, 2022 Category: Opthalmology Authors: FangJun Bao Bernardo T Lopes XiaoBo Zheng YuXin Ji JunJie Wang Ahmed Elsheikh Source Type: research
Corneal Biomechanics Losses Caused by Refractive Surgery
Curr Eye Res. 2022 Aug 24:1-7. doi: 10.1080/02713683.2022.2103569. Online ahead of print.ABSTRACTRecent advances, specifically in the understanding of the biomechanical properties of the cornea and its response to diseases and surgical interventions, have significantly improved the safety and surgical outcomes of corneal refractive surgery, whose popularity and demand continue to grow worldwide. However, iatrogenic keratectasia resulting from the deterioration in corneal biomechanics caused by surgical interventions, although rare, remains a global concern. On one hand, in vivo biomechanical evaluation, enabled by clinical...
Source: Current Eye Research - August 24, 2022 Category: Opthalmology Authors: FangJun Bao Bernardo T Lopes XiaoBo Zheng YuXin Ji JunJie Wang Ahmed Elsheikh Source Type: research
Corneal Biomechanics Losses Caused by Refractive Surgery
Curr Eye Res. 2022 Aug 24:1-7. doi: 10.1080/02713683.2022.2103569. Online ahead of print.ABSTRACTRecent advances, specifically in the understanding of the biomechanical properties of the cornea and its response to diseases and surgical interventions, have significantly improved the safety and surgical outcomes of corneal refractive surgery, whose popularity and demand continue to grow worldwide. However, iatrogenic keratectasia resulting from the deterioration in corneal biomechanics caused by surgical interventions, although rare, remains a global concern. On one hand, in vivo biomechanical evaluation, enabled by clinical...
Source: Current Eye Research - August 24, 2022 Category: Opthalmology Authors: FangJun Bao Bernardo T Lopes XiaoBo Zheng YuXin Ji JunJie Wang Ahmed Elsheikh Source Type: research
Long-term visual quality after small incision lenticule extraction (SMILE) and laser assisted subepithelial keratomileusis (LASEK) for low myopia
This study aims to compare the visual... (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - August 18, 2022 Category: Opthalmology Authors: Mengjun Fu, Meiyan Li, Ruoyan Wei, Chuanwei Zhang, Yangyi Huang, Lingling Niu, Xiaoying Wang, Haorun Zhang and Xingtao Zhou Tags: Research Source Type: research
Small Incision Lenticule Extraction (SMILE) and Laser in Situ Keratomileusis (LASIK) Used to Treat Myopia and Myopic Astigmatism: A Systematic Review and Meta-analysis of Randomized Clinical Trials
CONCLUSION: For predictability, LASIK was superior to SMILE. There were comparably safety and efficacy for the correction of myopia and myopic astigmatism in SMILE and LASIK. SA was smaller after SMILE than after LASIK.PMID:35912896 | DOI:10.1080/08820538.2022.2107399 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - August 1, 2022 Category: Opthalmology Authors: Lin Yao Minghong Zhang Dianqiang Wang Qian Zhao Shouyan Wang Haiqing Bai Source Type: research
Late-onset interface fluid syndrome: A case report and literature review
CONCLUSION: IFS represents an uncommon complication that could appear years after LASIK. Careful clinical examination and anterior segment optical coherence tomography promote early diagnosis. Similar cases may manifest due to elevated IOP of variable etiology or as a result of endothelial dysfunction. Depending on the etiology, IOP control or keratoplasty may resolve the condition.PMID:35866219 | DOI:10.1080/08820538.2022.2102928 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - July 22, 2022 Category: Opthalmology Authors: Spyridon Koronis Asterios Diafas Argyrios Tzamalis Maria Samouilidou Asimina Mataftsi Nikolaos Ziakas Source Type: research
