Cancer-Like Proliferation of Smooth Muscle Cells in Atherosclerosis
As an atherosclerotic plaque grows into a hotspot of inflammation and cell dysfunction in a blood vessel wall, it starts to draw in the nearby vascular smooth muscle cells that wrap the outside of the vessel. As researchers here note, these smooth muscle cells are altered by the plaque environment in ways that are analogous to the behavior of cancerous cells. They change, multiply, and accelerate the growth of a fatty plaque that will eventually rupture to cause a stroke or heart attack by blocking a downstream blood vessel. Atherosclerosis is the major cause of heart attacks and stroke around the world and occurs...
Source: Fight Aging! - May 8, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Healthcare ’ s Digital Evolution: Transforming Patient Care with Your EHR
This article will explore how digital records have improved the quality of patient care and the ways in which EHRs are continuing to evolve. We will also discuss how HCTec is helping hospitals, clinics, and other medical facilities improve patient outcomes and reduce costs through EHR upgrades. Electronic Health Records: A Game Changer Unless you were in the medical profession before the turn of the century, you may not have ever worked in an office or clinic without an electronic medical records (EMR) system. While these systems existed before the year 2000, at that time, many offices still utilized physical filing cabine...
Source: EMR and HIPAA - May 7, 2024 Category: Information Technology Authors: Guest Author Tags: C-Suite Leadership EMR-EHR Health IT Company Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops Bill Lewkowski EHR Consulting EHR Optimization HCTec Healthcare Scene Featured Healthcare Transformation Source Type: blogs

FreeDumb
This essay by Krugthulu is getting a lot of attention. (Gift link.) It seems that Ron DeSantis, having flamed out as a presidential candidate, isn ' t hanging up his combat boots in the culture wars. He ' s banned the production or sale of lab grown meat in the libertarian paradise of Florida. To be clear, such a product is a long way from commercial availability. We aren ' t talking about the plant-based meat substitutes you can buy today, but rather actual animal cells cultured in a laboratory, i.e. real meat without having to raise or kill an animal. That might strike you as weird or gross, but nobody is planning t...
Source: Stayin' Alive - May 7, 2024 Category: American Health Source Type: blogs

Will AI Revolutionize Surgical Care?   Yes, But Maybe Not How You Think
By MIKE MAGEE If you talk to consultants about AI in Medicine, it’s full speed ahead. GenAI assistants, “upskilling” the work force, reshaping customer service, new roles supported by reallocation of budgets, and always with one eye on “the dark side.” But one area that has been relatively silent is surgery. What’s happening there? In June, 2023, the American College of Surgeons (ACS) weighed in with a report that largely stated the obvious. They wrote, “The daily barrage of news stories about artificial intelligence (AI) shows that this disruptive technology is here to stay and on the verge of revol...
Source: The Health Care Blog - May 7, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Tech AI Mike Magee Surgery Source Type: blogs

Fight Aging! Newsletter, May 6th 2024
In conclusion, we found that elevated central aortic stiffness is associated with a greater decline in kidney function in old age. Since aPWV and cSBP both appear to be predictors of eGFR decline, it might be of interest to identify older individuals with elevated aortic stiffness. In this specific population, intensive blood pressure reduction might be justified in order to slow down the process of vascular aging and prevent kidney function decline. « Back to Top Cellular Senescence in Neurodegenerative Conditions https://www.fightaging.org/archives/2024/04/cellular-senescence-in-neurodegenera...
Source: Fight Aging! - May 5, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

106 Tuesday Blessings and Images for a Uplifting and Wonderful Day
Tuesday is here. An in-between day. Maybe you’re tired or bored today. Or maybe focused and ready to get your day started. I think you’ll find something helpful among these powerful Tuesday blessings, images and quotes no matter what headspace you’re in right now. Something to give your new energy, motivation, positivity or maybe an insight to turn your day around. And if you want even more inspiration for the rest of the week then check out this post with Wednesday blessings and also this one with Thursday blessings. Uplifting Tuesday Blessings “Tuesday morning blessings to you, my friend! Have a wonderful day....
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - May 3, 2024 Category: Consumer Health News Authors: Henrik Edberg Tags: Inspirational Quotes Personal Development Source Type: blogs

Presence With Patients is a Gift: Building Meaningful Patient Relationships
On this episode of the Academic Medicine Podcast, Katherine Chretien, MD, Grant Wilson, MD, and Michelle York, MD, join host Toni Gallo to discuss building meaningful relationships with patients, the small but impactful ways they show their patients they care, and the important role that learners play in connecting with patients and contributing to their care. This episode is now available through Apple Podcasts, Spotify, and anywhere else podcasts are available. A transcript is below. Check out the essay discussed in this episode. Read the essay: Chretien KC. Biopsy. Acad Med. 2023;98:1419. Li...
Source: Academic Medicine Blog - April 30, 2024 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Academic Medicine podcast doctor-patient relationship humanism learners medical students patient centered care Source Type: blogs

Cellular Senescence in Neurodegenerative Conditions
This open access review paper covers the high points of what is presently known of the contribution of senescent cells to neurodegenerative conditions. Somatic cells become senescent throughout life, largely as they reach the Hayflick limit to replication, but also due to damage or a toxic local environment. Senescent cells halt replication and begin to secrete pro-inflammatory signals to attract the immune system. In youth, senescent cells are rapidly cleared by programmed cell death or by immune cells. With age, the immune system becomes less efficient. As a consequence senescent cells begin to accumulate, and they help ...
Source: Fight Aging! - April 30, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Lean Digital: How Apps and Services Can Help Control Weight
Is anyone not obsessed with weight? The health care field certainly is. Researchers have found ties between high body weight and an oversized list of unhealthy conditions. Payers have invested enormous amounts of money in decreasing individuals’ body weights. A Congressional bill would promote behavioral therapy for obesity and extend Medicare coverage for drugs treating obesity. And yet weights continue to rise around the world, and the phenomenon starts at very young ages. The rapidly expanding use of GLP-1 drugs has been life-altering for many, but brings its own disappointments: They’re extremely expensive, req...
Source: EMR and HIPAA - April 29, 2024 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Analytics/Big Data Communication and Patient Experience Health IT Company Healthcare IT Telemedicine and Remote Monitoring Behavior Management Behavioral Change GLP-1 Healthcare Motivation Lean Digital Weight Loss S Source Type: blogs

Fight Aging! Newsletter, April 29th 2024
In conclusion, we assigned stemness scores to human samples and show evidence of a pan-tissue loss of stemness during human aging, which adds weight to the idea that stem cell deterioration may contribute to human aging. « Back to Top The Role of Immune Aging in Neurodegenerative Conditions https://www.fightaging.org/archives/2024/04/the-role-of-immune-aging-in-neurodegenerative-conditions/ The research community has come to see chronic inflammation and other age-related immune system dysfunctions as an important aspect of neurodegenerative conditions. Inflammation in the short term is n...
Source: Fight Aging! - April 28, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

10 Hacks To Master Your Focus and Crush Distractions (M)
Uncover the truth about multitasking, how to deal with interruptions, entering a flow state, finding the right environment and much more... (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - April 27, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Attention subscribers-only Source Type: blogs

Mitochondrial Transplantation Improves Muscle Function in Old Mice
In this study 15 female mice (24 months old) were randomized into two groups (placebo or mitochondrial transplantation). Isolated mitochondria from a donor mouse of the same sex and age were transplanted into the hindlimb muscles of recipient mice. The results indicated significant increases (ranging between ~36% and ~65%) in basal cytochrome c oxidase and citrate synthase activity as well as ATP levels in mice receiving mitochondrial transplantation relative to the placebo. Moreover, there were significant increases (approximately two-fold) in protein expression of mitochondrial markers in both glycolytic and oxidative mu...
Source: Fight Aging! - April 26, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

What If Generative AI Turned To Be A Flop In Healthcare?
The excitement surrounding generative AI is reaching a fever pitch. From tech giants to healthcare leaders, investment in this seemingly game-changing technology is exploding. We’re embracing the trend: we’ve written dozens of articles, created multiple videos, published an ebook, and recently launched a new short course.  However, amidst the enthusiasm, AI expert Gary Marcus raised an important question a few months ago: What if, for all its promise, generative AI fails to deliver long-term? While he outlined the pessimistic scenario in general, I wanted to dissect what genAI being a flop would mean in hea...
Source: The Medical Futurist - April 25, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine generative AI AI in heaalthcare Source Type: blogs

Reviewing Approaches to Improving Aged Stem Cell Function
A variety of approaches show some promise in improving the function of stem cells in aged tissues. Stem cell populations support their tissue by providing a supply of daughter somatic cells to replace losses. This supply diminishes over time as stem cells reduce their activity for reasons that descend from the known root causes of aging, but which are not fully understood in detail. To the degree that reduced stem cell function is a response to the aged environment rather than a consequence of damage inherent to these cells, then it is useful to find ways to force stem cells to be more active. Whether this is the case may ...
Source: Fight Aging! - April 24, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Genetics by the Numbers
Even though scientists have been studying genetics since the mid-19th century, they continue to make new discoveries about genes and how they impact our health on a regular basis. NIGMS researchers study how genes are expressed and regulated, how gene variants with different “spellings” of their genetic code affect health, and much more. Get the drop on DNA and the gist of genes with these fast facts: 3.2 Billion A marbled lungfish has a genome over 40 times larger than humans. Credit: iStock. That’s how many base pairs—or sets of genetic “letters”—make up the human genome. If you were...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 24, 2024 Category: Research Authors: Chrissa Chverchko Tags: Genes By the Numbers DNA Genomics Source Type: blogs