Particulate Air Pollution and Its Effects on the Mechanisms of Degenerative Aging
There is a great deal of data on air quality for researchers to peruse and link to the even larger set of data on human health and mortality. This has resulted in studies demonstrating strong correlations between higher levels of particulate air pollution and raised mortality, both in the context of exposure differences between large regions, and in the variations across a single metropolitan area. A large part of the problem is smoke, with industry, wildfires, and cooking fires all contributing to this issue to different degrees in different regions. Mechanistically, these particles lead to increased chronic inflammation ...
Source: Fight Aging! - November 17, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Endothelial Cell Senescence in Atherosclerosis
Senescent cells accumulate throughout the body with age. They are created constantly due to stresses placed upon cells, and when somatic cells reach the Hayflick limit on replication, and are cleared by the immune system. This process of clearance slows down with age, unfortunately, and so a burden of lingering senescent cells begins to build up. Senescent cells are disruptive to tissue structure and function, even when present in comparatively small numbers relative to other cells in a tissue, as a result of the pro-growth, pro-inflammatory signals that they generate.
Atherosclerosis involves the generation of fatt...
Source: Fight Aging! - November 16, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
MIDAS Healthcare Solutions Extends Series A Round With New Investment by MCPC Healthcare Fund
MIDAS Healthcare Solutions, Inc., the leading developer of technology-driven solutions to promote the safe use, storage, return, and disposal of controlled substances and other dangerous medications in hospitals and other healthcare institutions, announced today a $2 million investment from MCPC Healthcare Investment, LLC, the newly formed investment arm of Cleveland-based MCPC. This investment makes MCPC the largest single external shareholder of MIDAS and will allow MIDAS to expand its product development efforts in preparation for the 2024 product rollout.
This investment comes as the healthcare industry continues to b...
Source: EMR and HIPAA - November 16, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Bryan Scheetz Dr. Delos (Toby) Cosgrove Health IT Funding Health IT Fundings Health IT Investment Ira Grossman MCPC MCPC Healthcare Investment Michael Lafauci Midas MIDAS Healthcare Solutions Mike Source Type: blogs
Zealous for Wellness: Deciding What Kind of Change You Want
This article looks at the measurements and reporting strategies used by some specific companies. Their interventions, goals, and measures depend a lot on who’s paying for the service.
Wondr Health Gives Employers What They Ask For
Wondr Health, like so many companies in this article and in the value-based healthcare space generally, works with employers and payers. Ultimately, for many employers, the purpose of engaging Wondr Health’s behavioral interventions is to improve employee productivity.
According to chief medical officer Dr. Tim Church, some of Wondr Health’s clients focus on cutting down the c...
Source: EMR and HIPAA - November 15, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System LTPAC Telemedicine and Remote Monitoring Behavior Change behavioral health Cli Source Type: blogs
Reimagining Health Tech on the Cusp of ONC ’s Final HTI-1 Rule – Regulatory Talk Series
This article kicks off the Healthcare Regulatory Talk series.
There’s a collective holding of breath right now in health IT as the ONC appears likely to issue its final HTI-1 rule with new data standards for the next stage of healthcare interoperability soon. There’s a sense, too, that the industry is waiting for the proverbial other shoe to drop while simultaneously anticipating a new era of digital transformation to begin.
There’s no time to waste. Some key HTI-1 compliance deadlines require action before the end of 2024.To help jumpstart the path to compliance for EHR vendors, let’s take a deep dive into some ma...
Source: EMR and HIPAA - November 13, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Regulations 21st Century Cures Clinical Co-Pilot Clinical Decision Support Clinical Grade AI DrFirst EHR Certification EHR Source Type: blogs
TREM2 in the Development of Atherosclerosis
TREM2 is most studied in the context of Alzheimer's disease and related forms of neurodegeneration, where it seems to affect inflammation driven by microglia and loss of the ability of microglia to clear amyloid-β from the aging brain. Microglia are, more or less, the central nervous system version of the innate immune cells called macrophages that are found throughout the rest of the body. Atherosclerosis is the largest cause of human mortality, and is driven by macrophage dysfunction. Macrophages are responsible for clearing excess lipids from blood vessel walls, but when these cells become overwhelmed by local excesses...
Source: Fight Aging! - November 13, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, November 13th 2023
This study investigated the correlation among muscle strength, working memory (WM), and cortical hemodynamics during the N-back task of memory performance, and further explored whether cortical hemodynamics during N-back task mediated the relationship between muscle strength and WM performance. We observed that muscle strength (particularly grip strength) predicted WM of older adults in this cross-sectional study, which validated our hypothesis and expanded on previous research findings. Studies demonstrated that grip strength predicted executive function decline in patients with mild cognitive impairment. Other cross-sect...
Source: Fight Aging! - November 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
AI and special needs adults: The AI Guardian is in sight
Over the past decade I ' ve written on social media about the concept of an AI Guardian, but I realize I ' ve never put it into a blog post [4]. With the release of the LLM AIs [1] including ChatGP4,ChatGPT plugins, and recentlyGPT Agents (GPTs) the AI Guardian is much closer than I ' d expected. So it ' s time to write something.First, of course, I decided to ask ChatGPT. I ' ve never seen the concept of an AI Guardian online, but evidently I ' ve been looking in the wrong places. As of its April 2023 incarnationChatGPT4 has quite a bit to say:You: What do you know about the concept of an " AI Guardian " for sp...
Source: Be the Best You can Be - November 11, 2023 Category: Disability Tags: autism cognition cognitive impairment computer finance nsAI smartphone smartphone4all sport support technology Source Type: blogs
What Healthcare Policy or Regulation Would You Change if You Could?
Rules and regulations are put into place in order to keep people safe, on both the administrator end and the user end. This is especially important in the field of healthcare, where we are talking about people’s health and lives. But are all policies and regulations made by people with knowledge and experience in the field? Are these rules made with everyone’s best interest in mind? Or are there updates that need to be made in order to best fit the needs of our patients and our organizations? Has the environment changed in such a way that new policies or regulations are needed?
In search of an answer, we chat...
Source: EMR and HIPAA - November 10, 2023 Category: Information Technology Authors: Grayson Miller Tags: C-Suite Leadership Health IT Company Healthcare IT Regulations 21st Century Cures Act CareRev Dave Ross Health Catalyst Healthcare Regulations Hlth HLTH 2023 HLTH Conference Information Blocking Innsena Kat McDavitt Nurse Rei Source Type: blogs
Protected: Invasive species in the UK
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Source: David Bradley Sciencebase - Songs, Snaps, Science - November 10, 2023 Category: Science Authors: David Bradley Tags: Biology Environment Science Source Type: blogs
Invasive species in the UK
Invasive species, a term referring to non-native species introduced to new environments, often establish self-sustaining populations with negative impacts on local ecosystems, economies, or human health.
These invaders, encompassing plants, animals, fungi, or microorganisms (refer to the foot of this article for examples), typically arrive due to human activities such as trade, travel, or intentional release. In rare cases, invasive species might reach the UK through natural avenues, such as animal migration or wind dispersal. Climate change exacerbates the situation, creating new ecological niches due to shifts in tempera...
Source: David Bradley Sciencebase - Songs, Snaps, Science - November 10, 2023 Category: Science Authors: David Bradley Tags: Biology Environment Science Source Type: blogs
Glasses Provide Audible Prompts for Blind Wearers
A team at the University of Technology Sydney has developed an assistive technology for blind people and those with low vision. The system consists of glasses that can view their surroundings through an on-board camera, appraise the objects nearby using computer vision technology, and then play a sound that provides a cue for the wearer as to their surroundings. These “sound icons” could include a rustling sound when leaves are viewed, or a small bark when a dog appears, as examples. The technology could offer additional information on their environment for low vision wearers, and assist with daily tasks.
Technology...
Source: Medgadget - November 9, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Rehab UTSEngage Source Type: blogs
The Role of Senescent Cells in Age-Related Skeletal Diseases
Compelling evidence obtained from many studies in mice show that the accumulation of senescent cells with age is a major contributing factor in all of the common, inflammatory age-related conditions: cardiovascular disease, dementia, degeneration of bone tissue, and so forth. Senescent cells are created throughout life, mostly as somatic cells reach the Hayflick limit on replication, but accumulate in later life in large part because the immune system falters in its clearance of senescent cells. It still performs this function, but less efficiently, and the balance between creation and destruction of senescent cells tips t...
Source: Fight Aging! - November 8, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Towards Electromagnetic Interventions to Improve Mitochondrial Function
The use of electromagnetic fields to manipulate cell activity is understudied in comparison to the use of small molecules, so it is always possible that meaningfully beneficial electromagnetic therapies might be awaiting discovery. The present lack of said therapies may be much more a matter of the lack of funding and experienced research groups needed for exploration and follow through rather than either an inherently greater difficulty in developing such therapies or an inherent lack of potential in this strategy. Here, researchers discuss whether one can use electromagnetism to manipulate the function and quality contro...
Source: Fight Aging! - November 8, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
An Evolutionary Model in Which Aging is Selected
The present consensus on the evolution of aging is that it is an inevitable side effect of natural selection - aging isn't selected for per se, it is a byproduct. Evolution favors reproduction earlier in life rather than later in life, particularly in environments with high mortality due to disease or predation, and thus there is little pressure to select for mutations that enhance long-term maintenance of the body and brain. Looking at the examples of biology around us, the outcome of this process is near always biological systems that fail over time, in which their structure is optimized for early life success at the cos...
Source: Fight Aging! - November 7, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
