What If Generative AI Turned To Be A Flop In Healthcare?
The excitement surrounding generative AI is reaching a fever pitch. From tech giants to healthcare leaders, investment in this seemingly game-changing technology is exploding. We’re embracing the trend: we’ve written dozens of articles, created multiple videos, published an ebook, and recently launched a new short course.  However, amidst the enthusiasm, AI expert Gary Marcus raised an important question a few months ago: What if, for all its promise, generative AI fails to deliver long-term? While he outlined the pessimistic scenario in general, I wanted to dissect what genAI being a flop would mean in hea...
Source: The Medical Futurist - April 25, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine generative AI AI in heaalthcare Source Type: blogs

Reviewing Approaches to Improving Aged Stem Cell Function
A variety of approaches show some promise in improving the function of stem cells in aged tissues. Stem cell populations support their tissue by providing a supply of daughter somatic cells to replace losses. This supply diminishes over time as stem cells reduce their activity for reasons that descend from the known root causes of aging, but which are not fully understood in detail. To the degree that reduced stem cell function is a response to the aged environment rather than a consequence of damage inherent to these cells, then it is useful to find ways to force stem cells to be more active. Whether this is the case may ...
Source: Fight Aging! - April 24, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Genetics by the Numbers
Even though scientists have been studying genetics since the mid-19th century, they continue to make new discoveries about genes and how they impact our health on a regular basis. NIGMS researchers study how genes are expressed and regulated, how gene variants with different “spellings” of their genetic code affect health, and much more. Get the drop on DNA and the gist of genes with these fast facts: 3.2 Billion A marbled lungfish has a genome over 40 times larger than humans. Credit: iStock. That’s how many base pairs—or sets of genetic “letters”—make up the human genome. If you were...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 24, 2024 Category: Research Authors: Chrissa Chverchko Tags: Genes By the Numbers DNA Genomics Source Type: blogs

Leveraging AI to Address the Mental Health Crisis
The following is a guest article by Raj Tumuluri, Founder and CEO at Openstream.ai As healthcare providers, you are acutely aware of the staggering mental health challenges facing our societies today. Depression, anxiety, PTSD, and suicidal ideation have reached pandemic levels, exacerbated by the relentless pace of modern life. From the general population to students in high-stress environments and frontline workers, a severe shortage of clinical personnel has created harrowing bottlenecks in accessing timely mental health evaluations and care. The weight of this crisis calls for innovative solutions that can simultaneous...
Source: EMR and HIPAA - April 24, 2024 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Health IT Company Healthcare IT AI Avatars Behaviorial Health AI CAI Conversational AI Conversational Artificial Intelligence Healthcare AI mental health Mental Health AI Mental Health Crisis Openstream.ai Raj Source Type: blogs

Ready for Robots?
By KIM BELLARD When I was young, robots were Robby the Robot (Forbidden Planet, etc.), the unnamed robot in Lost in Space, or The Jetsons’ Rosey the Robot. Gen X and Millennials might think instead of the more malevolent Terminators (which, of course, are actually cyborgs). But Gen Z is likely to think of the running, jumping, back-flipping Atlas from Boston Dynamics, whose videos have entertained millions. Alas, last week Boston Dynamics announced it was discontinuing Atlas. “For almost a decade, Atlas has sparked our imagination, inspired the next generations of roboticists and leapt over technical barriers in ...
Source: The Health Care Blog - April 24, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Tech AI Kim Bellard robots Source Type: blogs

The Role of Immune Aging in Neurodegenerative Conditions
The research community has come to see chronic inflammation and other age-related immune system dysfunctions as an important aspect of neurodegenerative conditions. Inflammation in the short term is necessary for defense against pathogens and regeneration following injury. Unresolved, constant inflammation is harmful to tissue structure and function, however, changing cell behavior for the worse. In brain tissue, the effects of inflammatory signaling on the behavior of innate immune cells called microglia appears particularly important. Neurogenerative conditions are characterized by activated microglia. These microglia ar...
Source: Fight Aging! - April 23, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Exchanging, Managing, and Meaningfully Using Health Data in 2024
The following is a guest article by Jolie Ritzo, VP of Strategy and Network Engagement at Civitas Networks for Health Health data management in 2024 is both intricate and complex. From integrating artificial intelligence (AI) into healthcare and health data platforms to establishing robust data standards that reach beyond clinical settings to managing patient consent and increased patient access, it is fair to say that health data exchange and data management have many important intricacies worthy of careful attention. The scope of health data sharing and use of health data have expanded far beyond electronic health record...
Source: EMR and HIPAA - April 23, 2024 Category: Information Technology Authors: Guest Author Tags: Analytics/Big Data Health IT Company Healthcare IT Interoperability IT Infrastructure and Dev Ops CIvitas Civitas Networks for Health Data Segmentation For Privacy DS4P HDU HDUs Health Data Health Data Management Health Data Util Source Type: blogs

Ambitious Goals at Mitrix Bio
Mitrix Bio is one of the companies developing the means to produce large amounts of mitochondria for transplantation. Cells will take up new mitochondria from the surrounding environment, and mitochondria can be harvested from cell cultures. Mitochondrial function declines with age, the result of (a) gene expression changes in the cell nucleus that alter mitochondrial dynamics and the quality control process of mitophagy, and (b) damage to mitochondrial DNA. Evidence from animal studies suggests that replacing mitochondria in aged tissues produces benefits to health and organ function that last for long enough to be intere...
Source: Fight Aging! - April 23, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Investigating the Mechanisms of Very Early Alzheimer's Disease
Researchers here look at cellular dysfunction that may form the earliest stages of Alzheimer's disease, prior to the accumulation of misfolded amyloid-β and cognitive decline. In general, intervening early in the progression of a disease will always be easier, given the right target. The challenge lies in identifying and understanding the causative mechanisms, in an environment in which (a) there is little access to brain tissue in the earliest stages of Alzheimer's disease, and (b) the animal models are highly artificial, as mice do not normally develop anything resembling Alzheimer's disease, and thus may not accurately...
Source: Fight Aging! - April 23, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A Decline in Stemness in Many Human Stem Cell Populations with Aging
In conclusion, we assigned stemness scores to human samples and show evidence of a pan-tissue loss of stemness during human aging, which adds weight to the idea that stem cell deterioration may contribute to human aging. (Source: Fight Aging!)
Source: Fight Aging! - April 22, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Assessing Age-Related Changes in Muscle Stem Cell Biochemistry
Researchers here discuss some of the results achieved in building the Human Skeletal Muscle Aging Atlas. Focusing on stem cells in muscle tissue, they find numerous changes in gene expression relating to inflammation and reduced activity. The chronic inflammation characteristic of aging, provoked by senescent cells and innate immune reactions to molecular damage, is known to be involved in many of the dysfunctions of aging. Loss of stem cell activity, and thus a reduced supply of daughter somatic cells to replace losses and repair damage, is one of those dysfunctions. Skeletal muscle aging is a key contributor to ...
Source: Fight Aging! - April 22, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, April 22nd 2024
This study reveals a potential treatment for human mitochondrial diseases. « Back to Top A Population Study Correlates Air Pollution with Faster Cognitive Aging https://www.fightaging.org/archives/2024/04/a-population-study-correlates-air-pollution-with-faster-cognitive-aging/ A number of large epidemiological studies provide evidence for long-term exposure to greater levels of air pollution to accelerate the onset and progression of age-related disease. A few of these manage to control for the tendency for wealthier people to avoid living in areas with higher particulate air pollution, ...
Source: Fight Aging! - April 21, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Parkinson's Disease in the SENS View of Damage Repair
The Strategies for Engineered Negligible Senescence (SENS) is a view of aging as accumulated damage. Drawing from the extensive scientific literature on aging, the originators of SENS created an outline of the forms of cell and tissue damage that are fundamental causes of aging, in that they occur as a natural side-effect of the normal operation of our cellular biochemistry. So we might consider the loss of vital cells due to declining stem cell function, mutations to nuclear DNA and mitochondrial DNA, cross-linking of vital molecules in the extracellular matrix, accumulated metabolic waste in long-lived cells, generation ...
Source: Fight Aging! - April 19, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

How Thinking Like A Child Can Supercharge Your Learning And Attention (M)
Thinking like a five-year-old can help you learn more in a new environment. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - April 19, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Attention subscribers-only Source Type: blogs

The Evolution of Healthcare at Home, the Technology Driving this Change, and It ’ s Impact on the World of Healthcare
The world of healthcare is ever-evolving, especially when new technology is being adopted. One such new area is healthcare at home. Although we were forced into fully remote operations with COVID-19, we have been making modifications along the way and have discovered how beneficial it can be to our organizations and our patients. To make further strides though, we have to understand where we’ve come from, where we are now, and how it is making an impact. So let’s take a deeper look into healthcare at home to see how it has evolved over time, the technology that is driving this change, and how it is impacting ou...
Source: EMR and HIPAA - April 19, 2024 Category: Information Technology Authors: Grayson Miller Tags: Communication and Patient Experience Health IT Company Healthcare IT Telemedicine and Remote Monitoring Academy Medtech Ventures Alaina Victoria Brenden Hayden Cara Lunsford Carrie Nelson Cindy Gaines Digital Communication Discern He Source Type: blogs