Fight Aging! Newsletter, April 15th 2024
In conclusion, although several clinical trials targeting SnCs are ongoing, various questions about the biology of SnCs remain open, resulting in a gap between molecular and cellular data. Concerning the need, initiatives such as SenNet aiming to create openly accessible atlases of SnCs should contribute enormously to the area. Advances in understanding the subcellular structure, the heterogeneity, and the dynamics of SnCs require the integration of molecular and cellular techniques with data analysis packages to evaluate high throughput evidence from microscopy and flow cytometry. It is also necessary to develop new equip...
Source: Fight Aging! - April 14, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Culling in the name of …
If you have even a passing interest in the natural world, you will have most likely heard the phrase “invasive species”. By definition, a deliberate or accidental release of a species to an area beyond its natural environment where it then multiplies and causes damage to that environment and the native wildlife that relies on it. I discussed the UK issue of invasive species briefly last year and in the context of Muntjac and Black Hairstreak butterfly too.
Ecologist and conservationist Hugh Warwick tackles the issue in much more depth in his latest book – Cull of the Wild. Warwick is, as most of us are, ...
Source: David Bradley Sciencebase - Songs, Snaps, Science - April 12, 2024 Category: Science Authors: David Bradley Tags: Biology Environment Science Source Type: blogs
Securing Patient Data: A Practical Guide to Compliance in Open-Source Healthcare CMS
The following is a guest article by Jon Stewart, Co-Founder and President at ZenSource
Historically, the terms “patient data,” “open-source,” and “healthcare CMS” might have seemed incongruous. Open-source has often been perceived as the Wild West. But times have changed, and open-source platforms are now making significant strides, particularly in highly regulated industries. The modern world of the open web combined with a secure cloud, smarter planning, and robust support can enable healthcare organizations to enjoy the benefits of proprietary systems with the cost and flexibility of open-source platforms. S...
Source: EMR and HIPAA - April 11, 2024 Category: Information Technology Authors: Guest Author Tags: Analytics/Big Data Health IT Company Healthcare IT Security and Privacy Cloud Infrastructure CMS Cybersecurity Cybersecurity Training Healthcare CMS Jon Stewart Open Source Healthcare patient data Security Audit ZenSource Source Type: blogs
Political Science
I always do my best to write clearly and precisely, but it seems I don ' t always manage to get my meaning across. So let ' s try a couple of ideas again. Please read carefully, and think about what I actually write, not what you think I might think or what other people think. The First Amendment applies only to government. It constrains what government can do, it does not place any constraint of any kind on any other entity. The courts have interpreted it a bit more broadly than its literal language. If " congress shall make no law . . . " then the executive cannot have any legal authority to do what no law permits. ...
Source: Stayin' Alive - April 10, 2024 Category: American Health Source Type: blogs
Altera Digital Health: Leveraging the Cloud to Address the Needs of Rural and Community Hospitals
Rural and community hospitals face the same challenges as larger health systems. However, with smaller pools of talent and fewer resources, they need more help from their digital partners to address those challenges. Altera Digital Health (Altera) is leveraging the cloud to help this important customer segment.
Healthcare IT Today had the opportunity to sit down with Mark Pratt, MD – Chief Medical Officer for Paragon at Altera Digital Health to learn more about the company’s efforts for rural and community hospitals.
Outsized Impact
Right from the start of the interview it was clear that Dr. Pratt is deeply passionate ...
Source: EMR and HIPAA - April 10, 2024 Category: Information Technology Authors: Colin Hung Tags: EMR-EHR Health IT Company Healthcare IT Hospital - Health System Altera Digital Health Ambient Clinical Voice Cloud EHR Community Hospitals Dr. Mark Pratt Healthcare IT Video Interviews Healthcare Scene Featured HIMSS HIMSS 2024 Source Type: blogs
New U-RISE and MARC Funding Opportunities and Upcoming Webinar
We’re pleased to announce that the notices of funding opportunities (NOFOs) for the Undergraduate Research Training Initiative for Student Enhancement (U-RISE) (PAR-24-137) and Maximizing Access to Research Careers (MARC) (PAR-24-138) programs have been reissued. These NOFOs aim to promote broad participation in the biomedical research workforce by strengthening research training environments and expanding the pool of well-trained students who:
Complete their baccalaureate degree, and
Transition into and complete biomedical, research-focused higher degree programs (such as a Ph.D. or M.D./Ph.D.).
...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - April 9, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Funding Opportunities Meetings/Events Training/Fellowships/Career Development Preparing an Application Undergraduate Webinars Source Type: blogs
What Is Genetics?
This post is the first in our miniseries on genetics. Stay tuned for more!
Genetics is the study of genes and heredity—how traits are passed from parents to children through DNA. A gene is a segment of DNA that contains instructions for building one or more molecules that help the body work. Researchers estimate that humans have about 20,000 genes, which account for about 1 percent of our DNA. The remainder of the DNA plays a role in regulating genes, and scientists are researching other potential functions.
DNA Details
Credit: NIGMS.
DNA is shaped like a twisted ladder, called a double heli...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 8, 2024 Category: Research Authors: Chrissa Chverchko Tags: Genes Common questions DNA Genetics Miniseries Genomics Source Type: blogs
BHLHE40 and BHLHE41 Deletion May Make Macrophages and Microglia More Efficient
Macrophages in the body and microglia in the brain are similar forms of innate immune cell, responsible for clearing metabolic waste, among other duties. A number of age-related conditions involve the growing incapacity of macrophages or microglia, their transition to inflammatory states, and inability to clear debris and waste as they should. Atherosclerosis, for example, is arguably a condition caused by macrophage dysfunction, in which macrophages fail to clear excess cholesterol from blood vessel walls. Neurodegenerative conditions such as Alzheimer's disease, on the other hand, are characterized by the presence of act...
Source: Fight Aging! - April 8, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Homemade Shrimp Stock
Recently, my sister Marylou gifted me a box of Aneto fish broth that she had bought, but thought she would never use. I decided to use the broth to make a shrimp risotto, something I’ve made many times over the years, but always using chicken stock. (I love chicken stock…)
Well, let me tell you that shrimp risotto was a revelation. I had no idea it could taste so amazing. What had I been thinking all these years using chicken and not fish stock????
But there was a problem. As good as the Aneto’s fish broth is (and it is amazingly good), I inherently hate stock-in-a-box. Something about it just makes...
Source: The Blog That Ate Manhattan - April 7, 2024 Category: Primary Care Authors: Margaret Polaneczky, MD Tags: Soups Fish Stock Homemade Homemade stock Risotto Shrimp Shrimp Stock Source Type: blogs
Fight Aging! Newsletter, April 8th 2024
In this study, we tested a stem cell secretome product, which contains extracellular vesicles and growth factors, cytoskeletal remodeling factors, and immunomodulatory factors. We examined the effects of 4 weeks of 2×/week unilateral intramuscular secretome injections (quadriceps) in ambulatory aged male C57BL/6 mice (22-24 months) compared to saline-injected aged-matched controls.
Secretome delivery substantially increased whole-body lean mass and decreased fat mass, corresponding to higher myofiber cross-sectional area and smaller adipocyte size, respectively. Secretome-treated mice also had greater whole-bod...
Source: Fight Aging! - April 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Naked Mole Rats are Resistant to Ischemia, Such as Occurs Following a Heart Attack
On the one hand, naked mole-rats are most likely long-lived because they live underground, and thus suffer much lower rates of predation than other similarly sized mammals. Lower rates of extrinsic mortality appear to be a necessary prerequisite for the evolution of a longer species life span. On the other hand, living in a low-oxygen environment appears to have spurred the evolution of broad range of adaptations to that environment that incidentally happen to extend species longevity. Today's open access paper covers one aspect of those adaptations, a resistance to ischemia that reduces the harms resulting from the loss o...
Source: Fight Aging! - April 5, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Unlocking Healthcare ’ s Mobile Future: HIPAA-Compliant BYOD
When I’ve talked to CIOs about what’s keeping them up at night, they almost universally answer: security. No doubt it’s the biggest risk to a healthcare organization and the attackers only need a slight opening in your security defenses to wreak havoc.
That’s why we were particularly interested in this session at HIMSS 2024 that looked at how to create a HIPAA-Compliant BYOD program which balanced the security needs of a healthcare organization while still meeting the workflow needs of their users. Michael Karnezis, Director of Commercial Sales, and Vernon O’Donnell, President, Field Opera...
Source: EMR and HIPAA - April 4, 2024 Category: Information Technology Authors: John Lynn Tags: Ambulatory Health IT Company Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops LTPAC Security and Privacy BYID Security Healthcare Breaches Healthcare BYOD Healthcare Cybersecurity healthcare infrastructure Healt Source Type: blogs
Effective Shareholder Engagement to Address the Food Sector ’s SDG-Related Impacts in Mexico
Nora Mardirossian (Columbia University), Effective Shareholder Engagement to Address the Food Sector ’s SDG-Related Impacts in Mexico (2023): While investor engagement on environmental and social issues have grown in recent years, they remain limited in Mexico and other emerging markets. Investors... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - April 4, 2024 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
In Other Words: What Being Unionized Means for Molecules
Did you know that molecules can be unionized? But it doesn’t mean they form a labor union. In chemistry, unionized (pronounced “un-ionized”) is the opposite of ionized, which means “electrically charged.”
Credit: NIGMS.
Unionized molecules don’t have electrical charges because they have the same number of electrons and protons. Ionized molecules, also called ions, become charged by gaining or losing electrons. Ions with extra electrons, known as anions, have a negative charge. Ions with fewer electrons than normal, called cations, have a positive charge.
Unionization’s Impacts
A molecule’s c...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 3, 2024 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Tools and Techniques In Other Words Source Type: blogs
Arguing the Primacy of Predation in Determining Species Longevity
Researchers here review a variety of species and conclude that defense against predation is the most important determinant of species longevity. Long-lived species tend to have shells, or fly, or live underground. Evolution will not favor longevity until other factors reduce extrinsic mortality at the hands of predators. After that, proximate biochemical causes of longevity can come into play in what looks to be a wide variety of ways.
Various environmental morphological and behavioral factors can determine the longevity of representatives of various taxa. Long-lived species develop systems aimed at increasing org...
Source: Fight Aging! - April 3, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
