Presence With Patients is a Gift: Building Meaningful Patient Relationships
On this episode of the Academic Medicine Podcast, Katherine Chretien, MD, Grant Wilson, MD, and Michelle York, MD, join host Toni Gallo to discuss building meaningful relationships with patients, the small but impactful ways they show their patients they care, and the important role that learners play in connecting with patients and contributing to their care. This episode is now available through Apple Podcasts, Spotify, and anywhere else podcasts are available. A transcript is below. Check out the essay discussed in this episode. Read the essay: Chretien KC. Biopsy. Acad Med. 2023;98:1419. Li...
Source: Academic Medicine Blog - April 30, 2024 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Academic Medicine podcast doctor-patient relationship humanism learners medical students patient centered care Source Type: blogs

Cellular Senescence in Neurodegenerative Conditions
This open access review paper covers the high points of what is presently known of the contribution of senescent cells to neurodegenerative conditions. Somatic cells become senescent throughout life, largely as they reach the Hayflick limit to replication, but also due to damage or a toxic local environment. Senescent cells halt replication and begin to secrete pro-inflammatory signals to attract the immune system. In youth, senescent cells are rapidly cleared by programmed cell death or by immune cells. With age, the immune system becomes less efficient. As a consequence senescent cells begin to accumulate, and they help ...
Source: Fight Aging! - April 30, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Lean Digital: How Apps and Services Can Help Control Weight
Is anyone not obsessed with weight? The health care field certainly is. Researchers have found ties between high body weight and an oversized list of unhealthy conditions. Payers have invested enormous amounts of money in decreasing individuals’ body weights. A Congressional bill would promote behavioral therapy for obesity and extend Medicare coverage for drugs treating obesity. And yet weights continue to rise around the world, and the phenomenon starts at very young ages. The rapidly expanding use of GLP-1 drugs has been life-altering for many, but brings its own disappointments: They’re extremely expensive, req...
Source: EMR and HIPAA - April 29, 2024 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Analytics/Big Data Communication and Patient Experience Health IT Company Healthcare IT Telemedicine and Remote Monitoring Behavior Management Behavioral Change GLP-1 Healthcare Motivation Lean Digital Weight Loss S Source Type: blogs

Fight Aging! Newsletter, April 29th 2024
In conclusion, we assigned stemness scores to human samples and show evidence of a pan-tissue loss of stemness during human aging, which adds weight to the idea that stem cell deterioration may contribute to human aging. « Back to Top The Role of Immune Aging in Neurodegenerative Conditions https://www.fightaging.org/archives/2024/04/the-role-of-immune-aging-in-neurodegenerative-conditions/ The research community has come to see chronic inflammation and other age-related immune system dysfunctions as an important aspect of neurodegenerative conditions. Inflammation in the short term is n...
Source: Fight Aging! - April 28, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

10 Hacks To Master Your Focus and Crush Distractions (M)
Uncover the truth about multitasking, how to deal with interruptions, entering a flow state, finding the right environment and much more... (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - April 27, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Attention subscribers-only Source Type: blogs

Mitochondrial Transplantation Improves Muscle Function in Old Mice
In this study 15 female mice (24 months old) were randomized into two groups (placebo or mitochondrial transplantation). Isolated mitochondria from a donor mouse of the same sex and age were transplanted into the hindlimb muscles of recipient mice. The results indicated significant increases (ranging between ~36% and ~65%) in basal cytochrome c oxidase and citrate synthase activity as well as ATP levels in mice receiving mitochondrial transplantation relative to the placebo. Moreover, there were significant increases (approximately two-fold) in protein expression of mitochondrial markers in both glycolytic and oxidative mu...
Source: Fight Aging! - April 26, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

What If Generative AI Turned To Be A Flop In Healthcare?
The excitement surrounding generative AI is reaching a fever pitch. From tech giants to healthcare leaders, investment in this seemingly game-changing technology is exploding. We’re embracing the trend: we’ve written dozens of articles, created multiple videos, published an ebook, and recently launched a new short course.  However, amidst the enthusiasm, AI expert Gary Marcus raised an important question a few months ago: What if, for all its promise, generative AI fails to deliver long-term? While he outlined the pessimistic scenario in general, I wanted to dissect what genAI being a flop would mean in hea...
Source: The Medical Futurist - April 25, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine generative AI AI in heaalthcare Source Type: blogs

Reviewing Approaches to Improving Aged Stem Cell Function
A variety of approaches show some promise in improving the function of stem cells in aged tissues. Stem cell populations support their tissue by providing a supply of daughter somatic cells to replace losses. This supply diminishes over time as stem cells reduce their activity for reasons that descend from the known root causes of aging, but which are not fully understood in detail. To the degree that reduced stem cell function is a response to the aged environment rather than a consequence of damage inherent to these cells, then it is useful to find ways to force stem cells to be more active. Whether this is the case may ...
Source: Fight Aging! - April 24, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Genetics by the Numbers
Even though scientists have been studying genetics since the mid-19th century, they continue to make new discoveries about genes and how they impact our health on a regular basis. NIGMS researchers study how genes are expressed and regulated, how gene variants with different “spellings” of their genetic code affect health, and much more. Get the drop on DNA and the gist of genes with these fast facts: 3.2 Billion A marbled lungfish has a genome over 40 times larger than humans. Credit: iStock. That’s how many base pairs—or sets of genetic “letters”—make up the human genome. If you were...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 24, 2024 Category: Research Authors: Chrissa Chverchko Tags: Genes By the Numbers DNA Genomics Source Type: blogs

Leveraging AI to Address the Mental Health Crisis
The following is a guest article by Raj Tumuluri, Founder and CEO at Openstream.ai As healthcare providers, you are acutely aware of the staggering mental health challenges facing our societies today. Depression, anxiety, PTSD, and suicidal ideation have reached pandemic levels, exacerbated by the relentless pace of modern life. From the general population to students in high-stress environments and frontline workers, a severe shortage of clinical personnel has created harrowing bottlenecks in accessing timely mental health evaluations and care. The weight of this crisis calls for innovative solutions that can simultaneous...
Source: EMR and HIPAA - April 24, 2024 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Health IT Company Healthcare IT AI Avatars Behaviorial Health AI CAI Conversational AI Conversational Artificial Intelligence Healthcare AI mental health Mental Health AI Mental Health Crisis Openstream.ai Raj Source Type: blogs

Ready for Robots?
By KIM BELLARD When I was young, robots were Robby the Robot (Forbidden Planet, etc.), the unnamed robot in Lost in Space, or The Jetsons’ Rosey the Robot. Gen X and Millennials might think instead of the more malevolent Terminators (which, of course, are actually cyborgs). But Gen Z is likely to think of the running, jumping, back-flipping Atlas from Boston Dynamics, whose videos have entertained millions. Alas, last week Boston Dynamics announced it was discontinuing Atlas. “For almost a decade, Atlas has sparked our imagination, inspired the next generations of roboticists and leapt over technical barriers in ...
Source: The Health Care Blog - April 24, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Tech AI Kim Bellard robots Source Type: blogs

The Role of Immune Aging in Neurodegenerative Conditions
The research community has come to see chronic inflammation and other age-related immune system dysfunctions as an important aspect of neurodegenerative conditions. Inflammation in the short term is necessary for defense against pathogens and regeneration following injury. Unresolved, constant inflammation is harmful to tissue structure and function, however, changing cell behavior for the worse. In brain tissue, the effects of inflammatory signaling on the behavior of innate immune cells called microglia appears particularly important. Neurogenerative conditions are characterized by activated microglia. These microglia ar...
Source: Fight Aging! - April 23, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Exchanging, Managing, and Meaningfully Using Health Data in 2024
The following is a guest article by Jolie Ritzo, VP of Strategy and Network Engagement at Civitas Networks for Health Health data management in 2024 is both intricate and complex. From integrating artificial intelligence (AI) into healthcare and health data platforms to establishing robust data standards that reach beyond clinical settings to managing patient consent and increased patient access, it is fair to say that health data exchange and data management have many important intricacies worthy of careful attention. The scope of health data sharing and use of health data have expanded far beyond electronic health record...
Source: EMR and HIPAA - April 23, 2024 Category: Information Technology Authors: Guest Author Tags: Analytics/Big Data Health IT Company Healthcare IT Interoperability IT Infrastructure and Dev Ops CIvitas Civitas Networks for Health Data Segmentation For Privacy DS4P HDU HDUs Health Data Health Data Management Health Data Util Source Type: blogs

Ambitious Goals at Mitrix Bio
Mitrix Bio is one of the companies developing the means to produce large amounts of mitochondria for transplantation. Cells will take up new mitochondria from the surrounding environment, and mitochondria can be harvested from cell cultures. Mitochondrial function declines with age, the result of (a) gene expression changes in the cell nucleus that alter mitochondrial dynamics and the quality control process of mitophagy, and (b) damage to mitochondrial DNA. Evidence from animal studies suggests that replacing mitochondria in aged tissues produces benefits to health and organ function that last for long enough to be intere...
Source: Fight Aging! - April 23, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Investigating the Mechanisms of Very Early Alzheimer's Disease
Researchers here look at cellular dysfunction that may form the earliest stages of Alzheimer's disease, prior to the accumulation of misfolded amyloid-β and cognitive decline. In general, intervening early in the progression of a disease will always be easier, given the right target. The challenge lies in identifying and understanding the causative mechanisms, in an environment in which (a) there is little access to brain tissue in the earliest stages of Alzheimer's disease, and (b) the animal models are highly artificial, as mice do not normally develop anything resembling Alzheimer's disease, and thus may not accurately...
Source: Fight Aging! - April 23, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs