A machine learning approach for predicting treatment response of hyponatremia
Endocr J. 2024 Feb 2. doi: 10.1507/endocrj.EJ23-0561. Online ahead of print.ABSTRACTHyponatremia leads to severe central nervous system disorders and requires immediate treatment in some cases. However, a rapid increase in serum sodium (s-Na) concentration could cause osmotic demyelination syndrome. To achieve a safety hyponatremia treatment, we develop a prediction model of s-Na concentration using a machine learning. Among the 341 and 47 patients admitted to two tertiary hospitals for hyponatremia treatment (s-Na <130 mEq/L), those who were admitted to the general unit with urine sodium <20 mEq/L or treated with de...
Source: Endocrine Journal - February 4, 2024 Category: Endocrinology Authors: Tamaki Kinoshita Shintaro Oyama Daisuke Hagiwara Yoshinori Azuma Hiroshi Arima Source Type: research
An unusual complication of kidney biopsy: a case report
ConclusionKidney biopsy can be considered a routine procedure, and various bleeding episodes are most common in terms of complications, the detection of which is essential. Delayed bleeding complications are rare and can be caused by minor injuries. Our young patient had no injury during the hospitalization. We hypothesized that the developed serious and delayed bleeding complication resulted from effective immunosuppressive treatment. To the best of our knowledge, this is the first such case to date. However, renal biopsy in the case of thrombotic microangiopathy requires caution. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 3, 2024 Category: General Medicine Source Type: research
Molecules, Vol. 29, Pages 690: Adsorption Properties and Wettability of Ethoxy- and Propoxy- Derivatives of 2-Ethylhexanol as Sterically Specific Surfactant Structures
ochaska
2-ethylhexanol, an oxo alcohol competitively priced on the global market, has not been explored intensively as a raw material for surfactants, due to its weak hydrophobic character. However, its sequenced propoxylation and ethoxylation yield an innovative amphiphilic structure, which exhibits unique interfacial activity. The paper presents the differences in the fractional composition of innovative surfactants derived from 2-EH alcohol prepared using alkali and dimetalcyanide catalysts, as well as examples of excellent adsorption and interfacial properties of the latter. The adsorption behavior of the synthesiz...
Source: Molecules - February 2, 2024 Category: Chemistry Authors: Wies ław Hreczuch Beata Konopczy ńska Marcin Stasiak Adam Andrzejewski Krystyna Prochaska Tags: Article Source Type: research
Case report: Peri-procedural hydroxyurea helps minimize bleeding in patients with Essential Thrombocythemia associated with acquired von Willebrand syndrome
ConclusionPatients with extreme thrombocytosis are at high risk of bleeding due to acquired Von Willebrand Syndrome. Initiation of hydroxyurea at the time of bone marrow exam helps to control platelet count and minimizes the risk of peri-procedural hemorrhage in high-risk Essential Thrombocythemia patients with suspected acquired Von Willebrand Syndrome. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - February 1, 2024 Category: Cancer & Oncology Source Type: research
Molecules, Vol. 29, Pages 664: Reversible Surface Energy Storage in Molecular-Scale Porous Materials
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Forcible wetting of hydrophobic pores represents a viable method for energy storage in the form of interfacial energy. The energy used to fill the pores can be recovered as pressure&ndash;volume work upon decompression. For efficient recovery, the expulsion pressure should not be significantly lower than the pressure required for infiltration. Hysteresis of the wetting/drying cycle associated with the kinetic barrier to liquid expulsion results in energy dissipation and reduced storage efficiency. In the present work, we use open ensemble (Grand Canonical) Monte Carlo simulations to study the improvement of e...
Source: Molecules - January 31, 2024 Category: Chemistry Authors: Dusan Bratko Tags: Article Source Type: research
Accuracy of the 10 μg desmopressin test for differential diagnosis of Cushing syndrome: a systematic review and meta-analysis
We evaluated the accuracy of the 10 μg desmopressin test in differentiating Cushing disease (CD) from non-neoplastic hypercortisolism (NNH) and ectopic ACTH syndrome (EAS). A systematic review of studies on diagnostic test accuracy in patients with CD, NNH, or EAS subjected to the desmopressin test obtained from LILACS, PubMed, EMBASE, and CENTRAL databases was performed. Two reviewers independently selected the studies, assessed the risk of bias, and extracted the data. Hierarchical and bivariate models on Stata software were used for meta-analytical summaries. The certainty of evidence was measured using the GRADE (Grad...
Source: Frontiers in Endocrinology - January 30, 2024 Category: Endocrinology Source Type: research
Chemo-enzymatic derivatization of glycerol-based oligomers: structural elucidation and potential applications
Chembiochem. 2024 Jan 24:e202300839. doi: 10.1002/cbic.202300839. Online ahead of print.ABSTRACTSwitching from oil-based to bio-based feedstocks to ensure the green transition to a sustainable and circular future is one of the most pressing challenges faced by many industries worldwide. For the cosmetics and personal and house care industries there is a strong drive to accelerate this transition from the customers that starts favoring the purchase of naturally derived and bio-degradable products over the traditionally available products. In this work we developed a series of fully biobased macromolecules constituted of a g...
Source: Chembiochem - January 24, 2024 Category: Biochemistry Authors: Francesco Raboni Andrea Galatini Luca Banfi Renata Riva Alessandro Pellis Source Type: research
Clinical phenotyping of children with nocturnal enuresis: a key classification to improve the approach
The literature shows that nocturnal enuresis is not an isolated phenomenon of urinary loss during sleep, but encompasses a set of systemic clinical manifestations that significantly influence children's quality of life and development. However, the understanding of the clinical and physiological relationship of these systemic manifestations remains a clinical challenge. The recognition of these manifestations and their subsequent categorisation, may provide better insights into integrated clinical manifestations, facilitating the understanding of pathophysiological mechanisms, and promote increased assertiveness in the ass...
Source: Journal of Pediatric Urology - January 24, 2024 Category: Urology & Nephrology Authors: Rita Pavione Rodrigues Pereira, Aline Mari Mazzali Pessoa Martins, Isabela Teixeira Mendes de Carvalho, Luana Daniele Kel de Souza, Patricia Francao, Cristiano Mendes Gomes, Rejane de Paula Bernardes, Karine Furtado Meyer, Eliane Maria Garcez Oliveira da Source Type: research
Design of highly robust super-liquid-repellent surfaces that can resist high-velocity impact of low-surface-tension liquids
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC00966A, PaperYingke Wang, Yue Fan, Hongtao Liu, Shuai Wang, Lin Liu, Yingying Dou, Shilin Huang, Juan Li, Xuelin Tian Super-liquid-repellent surfaces capable of preventing wetting by various liquids have tremendous applications. However, high liquid repellency relies on surface texturing to minimize the solid-liquid interfacial contact, which generally results in... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 23, 2024 Category: Chemistry Authors: Yingke Wang Source Type: research
Novel fabrication of mixed wettability micromodels for pore-scale studies of fluid –rock interactions
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Abdullah AlOmier, Dongkyu Cha, Subhash Ayirala, Ali Al-Yousef, Hussein Hoteit Fabrication of micromodels mimicking natural rocks with mixed wettability, combining hydrophobic and hydrophilic characteristics. Surface modifications represent mineral heterogeneity, highlighting diverse wetting properties in the pore structure. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 23, 2024 Category: Chemistry Authors: Abdullah AlOmier Source Type: research
Ocular Involvement in Graft-versus-Host Disease
Klin Monbl Augenheilkd. 2024 Jan 23. doi: 10.1055/a-2218-0237. Online ahead of print.ABSTRACTIn ocular graft-versus-host disease (GVHD), an inflammatory reaction occurs at the ocular surface after transplantation of allogeneic hematopoietic stem cells. Self-reactive T cells of the donor are particularly responsible for this. This can lead to a pronounced wetting disorder of the ocular surface, conjunctival hyperemia, and corneal ulceration up to perforation. The ocular GVHD is associated with a high degree of suffering, such as pain, photophobia, and reduction in visual acuity. This review provides an overview of typical o...
Source: Klinische Monatsblatter fur Augenheilkunde - January 23, 2024 Category: Opthalmology Authors: Christoph Tappeiner Arnd Heiligenhaus Tina Dietrich-Ntoukas Source Type: research
Magnetic resonance imaging of trickle flow
This article employs Magnetic Resonance Imaging (MRI) to characterize the three-dimensional distribution of the two-phase trickle flow within a slender tube. Three quantities are characterized: gas-liquid-solid distribution, particle wetting efficiency, and the flow field. Structure and flow MRI images are processed to calculate these quantities. Additionally, a novel postprocessing technique is introduced to determine the liquid distribution over individual particle surfaces. This distribution is determined at several axial and radial positions. (Source: AIChE Journal)
Source: AIChE Journal - January 23, 2024 Category: Science Authors: Ali Fathiganjehlou,
Kay A. Buist,
E. A. J. F. (Frank) Peters,
Larry A. H. J. de Graaf,
J. A. M. (Hans) Kuipers Tags: RESEARCH ARTICLE Source Type: research
Desmopressin to reduce periprocedural bleeding and transfusion: a systematic review and meta-analysis
In conclusion, desmopressin likely re duces periprocedural blood loss and the number of units of blood transfused in small trials with methodologic limitations. However, the risk of hypotension needs to be mitigated. Large trials should evaluate desmopressin alongside tranexamic acid and enroll patients with advanced kidney disease. (Source: Perioperative Medicine)
Source: Perioperative Medicine - January 23, 2024 Category: Surgery Source Type: research
Transient Central Diabetes Insipidus (Arginine Vasopressin Deficiency) Following SARS-CoV-2 Vaccination: A Case Report and Literature Review
CONCLUSION: Neurohypophysitis can have an abrupt onset independently of the etiology. Central DI is a rather exceptional event after SARS-CoV-2 vaccination but should be recalled in case of sudden polyuria and polydipsia. DI is indeed reported even after SARS-CoV-2 infection, thus, this report should not discourage the use of mRNA-based vaccines. Furthermore, our case demonstrates that full recovery of posterior pituitary function is possible after immunization with anti-Covid-19 BNT162b2 vaccine. Further studies are needed to clarify the possible mechanism relating to SARS-CoV-2 vaccination and this rare adverse event.PMI...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - January 20, 2024 Category: Endocrinology Authors: Pierluigi Mazzeo Filippo Ceccato Renzo Manara Cinzia Mazzon Mattia Barbot Source Type: research
