Chemo-enzymatic derivatization of glycerol-based oligomers: structural elucidation and potential applications

Chembiochem. 2024 Jan 24:e202300839. doi: 10.1002/cbic.202300839. Online ahead of print.ABSTRACTSwitching from oil-based to bio-based feedstocks to ensure the green transition to a sustainable and circular future is one of the most pressing challenges faced by many industries worldwide. For the cosmetics and personal and house care industries there is a strong drive to accelerate this transition from the customers that starts favoring the purchase of naturally derived and bio-degradable products over the traditionally available products. In this work we developed a series of fully biobased macromolecules constituted of a glycerol-based oligoester backbone. Based on the subsequent derivatization with fatty acids or peptides, the resulting products may find application as emulsifiers, wetting agents, and potential vectors for the delivery of bioactive peptides. All steps of the resulting macromolecules were conducted following the green chemistry principles with no toxic or environmentally damaging compounds that were used in the overall production process.PMID:38265820 | DOI:10.1002/cbic.202300839
Source: Chembiochem - Category: Biochemistry Authors: Source Type: research