Pulmonary-arterial-hypertension (PAH)-on-a-chip: fabrication, validation and application
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Taslim A. Al-Hilal, Ali Keshavarz, Hossam Kadry, Behnaz Lahooti, Ahmed Al-Obaida, Zhenya Ding, Wei Li, Roger Kamm, Ivan F. McMurtry, Tim Lahm, Eva Nozik-Grayck, Kurt R. Stenmark, Fakhrul Ahsan Current animal and cellular models only partially recapitulate the pathophysiology of PAH. Our PAH-on-a-chip model can mimic the major pathologies of PAH such as pulmonary arterial remodeling and sex disparity and help develop PAH therapeutics. To cite this article before page numbers are assigned, use the DOI form of citation above. The c...
Source: RSC - Lab Chip latest articles - August 5, 2020 Category: Chemistry Authors: Taslim A. Al-Hilal Source Type: research

Correction: A bespoke microfluidic pharmacokinetic compartment model for drug absorption using artificial cell membranes
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Jaime L. Korner, Elanna B. Stephenson, Katherine S. Elvira To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - August 5, 2020 Category: Chemistry Authors: Jaime L. Korner Source Type: research

SNAPflex: a paper-and-plastic device for instrument-free RNA and DNA extraction from whole blood
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00277A, PaperNikunja Kolluri, Nikolas Albarran, Andy Fan, Alex Olson, Manish Sagar, Anna Young, Jose Gomez-Marquez, Catherine M Klapperich Nucleic acid amplification tests (NAATs), which amplify and detect pathogen nucleic acids, are vital methods to diagnose diseases, particularly in cases where patients exhibit low levels of infection. For many... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - August 5, 2020 Category: Chemistry Authors: Nikunja Kolluri Source Type: research

Isolation of Extracellular Vesicles from Small Volumes of Plasma by Microfluidic Aqueous Two-Phase System
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00345J, PaperBohoon Han, Sumi Kim, Geeyoon Seo, Youhee Heo, Seok Chung, Ji Yoon Kang As conventional bulky methods for extracellular vesicle (EV) separation are unsuitable with small volumes of samples, microfluidic devices are thought to offer the solution for the integrated and automatic processing... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - August 5, 2020 Category: Chemistry Authors: Bohoon Han Source Type: research

Finger-Powered Fluidic Actuation and Mixing via MultiJet 3D Printing
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00488J, PaperEric Christopher Sweet, Rudra Mehta, Yifan Xu, Ryan Jew, Rachel Lin, Liwei Lin Additive manufacturing, or three-dimensional (3D) printing, has garnered significant interest in recent years towards the fabrication of sub-millimeter scale devices for an ever-widening array of chemical, biological and biomedical applications.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - August 5, 2020 Category: Chemistry Authors: Eric Christopher Sweet Source Type: research

A modular microarray imaging system for highly specific COVID-19 antibody testing
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Per Niklas Hedde, Timothy J. Abram, Aarti Jain, Rie Nakajima, Rafael Ramiro de Assis, Trevor Pearce, Algis Jasinskas, Melody N. Toosky, Saahir Khan, Philip L. Felgner, Enrico Gratton, Weian Zhao The TinyArray imager, a robust inexpensive portable imaging device, can detect antibodies against SARS-CoV-2 based on coronavirus antigen microarrays. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - August 3, 2020 Category: Chemistry Authors: Per Niklas Hedde Source Type: research

Partial thermal imidization of polyelectrolyte multilayer cell tethering surfaces (TetherChip) enables efficient cell capture and microtentacle fixation for circulating tumor cell analysis
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Julia A. Ju, Cornell J. Lee, Keyata N. Thompson, Eleanor C. Ory, Rachel M. Lee, Trevor J. Mathias, Stephen J. P. Pratt, Michele I. Vitolo, Christopher M. Jewell, Stuart S. Martin TetherChip is an optimized nanosurface comprised of a polyelectrolyte multilayer and a terminal lipid layer in a microfluidics system to enable the study of non-adherent tumor cell behaviors that are relevant to cancer metastasis. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Soci...
Source: RSC - Lab Chip latest articles - August 3, 2020 Category: Chemistry Authors: Julia A. Ju Source Type: research

A microfluidic strategy for the detection of membrane protein interactions
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Yuewen Zhang, Therese W. Herling, Stefan Kreida, Quentin A. E. Peter, Tadas Kartanas, Susanna T örnroth-Horsefield, Sara Linse, Tuomas P. J. Knowles Membrane proteins are gatekeepers for exchange of information and matter between the intracellular and extracellular environment. This paper opens up a route to probe membrane protein interactions under native solution conditions using microfluidics. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society o...
Source: RSC - Lab Chip latest articles - August 3, 2020 Category: Chemistry Authors: Yuewen Zhang Source Type: research

Development of a Cardiac-and-Piezoelectric Hybrid System for the Application of Drug Screening
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00433B, PaperYun-Han Huang, Chiou-Fong Yang, YU-HSIANG HSU In this paper, a cardiac-and-piezoelectric hybrid system is developed for drug screening. The core structure is a polyvinylidene-fluoride piezoelectric membrane that serves as a flexible structure to interact with hiPSC... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - August 3, 2020 Category: Chemistry Authors: Yun-Han Huang Source Type: research

Construction of core-shell microcapsules via focused surface acoustic wave microfluidics
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00123F, CommunicationShaobo Jin, Xueyong Wei, Juan Ren, Zhuangde Jiang, Chris Abell, Ziyi Yu The ability to construct core-shell microcapsules has the potential to shift the paradigm in the development of new delivery systems for nutrients, cosmetics, and drugs. In this work, we demonstrate... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - August 1, 2020 Category: Chemistry Authors: Shaobo Jin Source Type: research

Correction: Development and characterisation of acoustofluidic devices using detachable electrodes made from PCB
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Roman Mikhaylov, Fangda Wu, Hanlin Wang, Aled Clayton, Chao Sun, Zhihua Xie, Dongfang Liang, Yinhua Dong, Fan Yuan, Despina Moschou, Zhenlin Wu, Ming Hong Shen, Jian Yang, Yongqing Fu, Zhiyong Yang, Christian Burton, Rachel J. Errington, Marie Wiltshire, Xin Yang To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - August 1, 2020 Category: Chemistry Authors: Roman Mikhaylov Source Type: research

Controlled pharmacokinetic anti-cancer drug concentration profiles lead to growth inhibition of colorectal cancer cells in a microfluidic device
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Job Komen, Eiko Y. Westerbeek, Ruben W. Kolkman, Julia Roesthuis, Caroline Lievens, Albert van den Berg, Andries D. van der Meer We present a microfluidic device to expose cancer cells to a dynamic,in vivo-like concentration profile of a drug, and quantify efficacy on-chip. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 31, 2020 Category: Chemistry Authors: Job Komen Source Type: research

Extracellular recording of direct synaptic signals with a CMOS-nanoelectrode array
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00553C, PaperJeffrey Abbott, Tianyang Ye, Keith Krenek, Rona S. Gertner, Wenxuan Wu, Han Sae Jung, Donhee Ham, Hongkun Park The synaptic connections between neurons are traditionally determined by correlating the action potentials (APs) of a pre-synaptic neuron and small-amplitude subthreshold potentials of a post-synaptic neuron using invasive intracellular techniques,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 31, 2020 Category: Chemistry Authors: Jeffrey Abbott Source Type: research

Multiplexed End-point Microfluidic Chemotaxis Assay using Centrifugal Alignment
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00311E, CommunicationSampath Satti, Pan Deng, Kerryn Matthews, Simon P. Duffy, Hongshen Ma A fundamental challenge to multiplexing microfluidic chemotaxis assays at scale is the requirement for time-lapse imaging to continuously track migrating cells. Drug testing and drug screening applications require the ability... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 30, 2020 Category: Chemistry Authors: Sampath Satti Source Type: research

Modeling iontophoretic drug delivery in a microfluidic device
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Maryam Moarefian, Rafael V. Davalos, Luke Achenie, Danesh K. Tafti, Caroline N. Jones Iontophoresis employs low-intensity electrical voltage and continuous constant current to direct a charged drug into a tissue. Iontophoretic drug delivery has recently been used as a novel method for cancer... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 30, 2020 Category: Chemistry Authors: Maryam Moarefian Source Type: research

Compact 256-channel multi-well microelectrode array system for in vitro neuropharmacology test
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00384K, PaperDaejeong Kim, Hongki Kang, Yoonkey Nam Microelectrode arrays (MEAs) have been extensively used to measure extracellular spike activity from cultured neurons using multiple electrodes embedded in a planar glass substrate. It has been implemented to investigate... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 29, 2020 Category: Chemistry Authors: Daejeong Kim Source Type: research

Development of elastic artificial vessels with a digital pulse flow system to investigate the risk of restenosis and vasospasm
Lab Chip, 2020, Advance Article DOI: 10.1039/D0LC00533A, PaperYalei Lv, Guoqiang Li, Hongyu Peng, Yanping Liu, Jingru Yao, Gao Wang, Jianfeng Sun, Jinghua Liu, Hongfei Zhang, Guo Chen, Liyu Liu We constructed elastic artificial vessels with a digital pulse flow system, which provide anin vitro research platform that approaches thein vivo microenvironment and facilitates a quantitative study on investigating the risk of restenosis and vasospasm. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 29, 2020 Category: Chemistry Authors: Yalei Lv Source Type: research

Fabrication of Vascular Smooth Muscle-like Tissues Based on Self-Organization of Circumferentially Aligned Cells in Microengineered Hydrogels
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00544D, PaperTao Sun, Qing Shi, Qian Liang, Yibing Yao, Huaping Wang, Junzhong Sun, Qiang Huang, Toshio Fukuda Circumferential alignment of vasucalr smooth muscle cells (vSMCs) is critical to form an in vivo-like vasucalr smooth muscle layer in vitro. Although many techniques to elicit such alignment on 3D... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 29, 2020 Category: Chemistry Authors: Tao Sun Source Type: research

Correction: 4D synchrotron microtomography and pore-network modelling for direct in situ capillary flow visualization in 3D printed microfluidic channels
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Agnese Piovesan, Tim Van De Looverbosch, Pieter Verboven, Clement Achille, Cesar Parra Cabrera, Elodie Boller, Yin Cheng, Rob Ameloot, Bart Nicolai To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 29, 2020 Category: Chemistry Authors: Agnese Piovesan Source Type: research

NanoPADs and NanoFACEs: an optically transparent nanopaper-based device for biomedical applications
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00226G, PaperBinbin Ying, Siwan Park, Longyan Chen, Xianke Dong, Edmond Young, Xinyu Liu Paper has been one of the most popular materials of choice for biomedical applications including for bioanalysis and cell biology studies. Regular cellulose paper-based devices, however, have several key limitations... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 29, 2020 Category: Chemistry Authors: Binbin Ying Source Type: research

A microfluidic tissue chip recapitulating human pulmonary arterial hypertension: Fabrication, validation and application
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Taslim A Al-Hilal, Ali Keshavarz, Hossam Kadry, Behnaz Lahooti, Ahmed Al-Obaida, Zhenya Ding, Wei Li, Roger D. Kamm, Ivan F. McMurtry, Tim Lahm, Eva Nozik-Grayck, Kurt R Stenmark, Ahsan Fakhrul Currently used animal and cellular models for pulmonary arterial hypertension (PAH) only partially recapitulate its pathophysiology in humans and are thus inadequate in reproducing the hallmarks of the disease, inconsistent... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 29, 2020 Category: Chemistry Authors: Taslim A Al-Hilal Source Type: research

Scaling of deterministic lateral displacement devices to a single column of bumping obstacles
We describe a deterministic lateral displacement (DLD) for particle separation with only a single column of bumping features. The bifurcation of fluid streams at obstacles is not set by the... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 28, 2020 Category: Chemistry Authors: weibin liang Source Type: research

3D-Printed Metal Column for Micro Gas Chromatography
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00540A, PaperSooyeol Phyo, Sung Choi, Jaeheok Jang, Sun Choi, Jiwon Lee In this work, 3D-printed metal column was developed towards micro gas chromatography (GC) applications and its properties and gas separation performances were characterized. By using Ti6Al4V Grade 23 powder, a... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 28, 2020 Category: Chemistry Authors: Sooyeol Phyo Source Type: research

Electro-responsive hydrogel-based microfluidic actuator platform for photothermal therapy
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00458H, PaperJang Ho Ha, Ha Hee Shin, Hyung Woo Choi, Jae Hyun Lim, Sung Joon Mo, Christian D. Ahrberg, Jong Min Lee, Bong Geun Chung The electrical stimuli play an important role in regulating the delivery of the plasmonic nanomaterials with cancer targeting peptides. Here, we developed the electro-responsive hydrogel-based microfluidic actuator platform for brain... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 27, 2020 Category: Chemistry Authors: Jang Ho Ha Source Type: research

Multiplexed Blood-Brain Barrier Organ-on-Chip
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Mariia Zakharova, Marciano Palma do Carmo, Marinke van der Helm, Hai Le-The, Mees de graaf, Valeria V Orlova, Albert van den Berg, Andries D. van der Meer, Kerensa Broersen, Loes Segerink Organ-on-chip devices are thoroughly studied in academia and industry due to their high potential in pharmaceutical and biomedical applications. However, most of the existing organ-on-chip models focus on proof of... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 27, 2020 Category: Chemistry Authors: Mariia Zakharova Source Type: research

Label-free ferrohydrodynamic separation of exosome-like nanoparticles
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00609B, PaperYang Liu, Wujun Zhao, Rui Cheng, Meghan T Logun, Maria del Mar Zayas-Viera, Lohitash Karumbaiah, Leidong Mao Isolation of exosomes from biological samples provides a minimally-invasive alternative for basic understanding, diagnosis, and prognosis of metastatic cancers. The biology and clinical values of exosomes are under intensive investigation,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 25, 2020 Category: Chemistry Authors: Yang Liu Source Type: research

Droplet Delivery and Nebulization System Using Surface Acoustic Wave for Mass Spectrometry
We present a piezoelectric transducer for standing wave surface acoustic wave nebulization (SW-SAWN). The transducer nebulizes nonvolatile analytes present in bulk fluid into ambient air after which aerosolized drops are... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 25, 2020 Category: Chemistry Authors: Di Sun Source Type: research

Single-Molecule Confinement with Uniform Electrodynamic Nanofluidics
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Siddharth Ghosh, Ingo Gregor, Narain Karedla Until now, we could not engineer Nature's ability to dynamically handle diffusing single molecules at liquid-phase as it takes place in pore-forming proteins and tunnelling-nanotubes. Consistent handling of individual single... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 24, 2020 Category: Chemistry Authors: Siddharth Ghosh Source Type: research

Critical Review: digital resolution biomolecular sensing for diagnostics and life science research
Lab Chip, 2020, Advance Article DOI: 10.1039/D0LC00506A, Critical ReviewQinglan Huang, Nantao Li, Hanyuan Zhang, Congnyu Che, Fu Sun, Yanyu Xiong, Taylor D. Canady, Brian T. Cunningham We review the current state-of-the-art in the field of digital resolution biosensing, describing the capabilities of commercially available technology platforms, as well as those have been described in published literature. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 24, 2020 Category: Chemistry Authors: Qinglan Huang Source Type: research

Organ-on-chip model shows that ATP release through connexin hemichannels drives spontaneous Ca2+ signaling in non-sensory cells of the greater epithelial ridge in the developing cochlea
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Flavia Mazzarda, Annunziata D'Elia, Roberto Massari, Adele De Ninno, Francesca Romana Bertani, Luca Businaro, Gaia Ziraldo, Veronica Zorzi, Chiara Nardin, Chiara Peres, Francesco Chiani, Abraham Tettey-Matey, Marcello Raspa, Ferdinando Scavizzi, Alessandro Soluri, Anna Maria Salvatore, Jun Yang, Fabio Mammano Using microfluidics, ATP biosensors, multiphoton microscopy and genetically targeted mice, we show that ATP release through connexin hemichannels, and not pannexin 1 channels, underlies spontaneous Ca2+ wave propagation in ...
Source: RSC - Lab Chip latest articles - July 24, 2020 Category: Chemistry Authors: Flavia Mazzarda Source Type: research

OSTE+ for in situ SAXS analysis with droplet microfluidic devices
Lab Chip, 2020, Advance Article DOI: 10.1039/D0LC00454E, PaperTobias Lange, Sophie Charton, Thomas Bizien, Fabienne Testard, Florent Malloggi Thin full OSTE+ chip fabrication and characterization forin situ SAXS studies. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 22, 2020 Category: Chemistry Authors: Tobias Lange Source Type: research

Polymorphic calcium alginate microfibers assembled using a programmable microfluidic field for cell regulation
Lab Chip, 2020, Advance Article DOI: 10.1039/D0LC00517G, PaperQiwei Huang, Yingyi Li, Longfei Fan, John H. Xin, Hui Yu, Dongdong Ye A single microfluidic chip was used to control a complex fluid field to prepare polymorphic microfibers for cell regulation. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 22, 2020 Category: Chemistry Authors: Qiwei Huang Source Type: research

Microfluidic chip enabled one-step synthesis of biofunctionalized CuInS2/ZnS quantum dots
Lab Chip, 2020, Advance Article DOI: 10.1039/D0LC00202J, PaperSiyi Hu, Butian Zhang, Shuwen Zeng, Liwei Liu, Ken-Tye Yong, Hanbin Ma, Yuguo Tang A novel and robust method for synthesizing the biofunctionalized CuInS2/ZnS quantum dots by the microfluidics chips. The synthesized quantum dot materials are easy to be modified by surface targeted biomolecules and can be used in targeted cell imaging research. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 22, 2020 Category: Chemistry Authors: Siyi Hu Source Type: research

Recognition and location of motile microorganisms by shape-matching photoluminescence micropatterns
Lab Chip, 2020, Advance Article DOI: 10.1039/D0LC00465K, PaperMeng Su, Zhandong Huang, Jing Liu, Yifan Li, Qi Pan, Zeying Zhang, Zheng Li, Zheren Cai, Bingda Chen, Shuoran Chen, Fengyu Li, Yanlin Song A method is proposed to recognize and locate motile microorganisms at the microscale. Printed photoluminescence patterns have the character of shape matching and uniform light guiding, which prompt the microscale artificial selection and location. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 20, 2020 Category: Chemistry Authors: Meng Su Source Type: research

An affordable 3D-printed positioner fixture improves the resolution of conventional milling for easy prototyping of acrylic microfluidic devices.
We present a simple and low-cost positioner fixture to improve the fabrication resolution of acrylic microchannels using conventional milling machines. The positioner fixture is a mechatronic platform that consists of... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 18, 2020 Category: Chemistry Authors: Pablo Enrique Guevara-Pantoja Source Type: research

A pressure-actuated flow cell for soft X-ray spectromicroscopy in liquid media
We present and fully characterize a flow cell dedicated to imaging in liquid at the nanoscale. Its use as a routine sample environment for soft X-ray spectromicroscopy is demonstrated, in... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 17, 2020 Category: Chemistry Authors: Charlie Gosse Source Type: research

Quantitative design strategies for fine control of oxygen in microfluidic systems
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00350F, PaperVenktesh S. Shirure, Sandra Lam, Bhupinder Shergill, Yunli E. Chu, Natalie R. Ng, Steven George Hypoxia, or low oxygen (O2) tension, is a central feature of important disease processes including wound healing and cancer. Subtle temporal and spatial variations ( ≤ 1% change) in the concentration... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 17, 2020 Category: Chemistry Authors: Venktesh S. Shirure Source Type: research

High-speed particle detection and tracking in microfluidic devices using event-based sensing
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Jessie Howell, Tansy C. Hammarton, Yoann Altmann, Melanie Jimenez Visualising fluids and particles within channels is a key element of microfluidic work. Current imaging methods for particle image velocimetry often require expensive high-speed cameras with powerful illuminating sources, thus... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 17, 2020 Category: Chemistry Authors: Jessie Howell Source Type: research

Digital Resolution Biomolecular Sensing for Diagnostics and Life Science Research
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00506A, Critical ReviewQinglan Huang, Nantao Li, Hanyuan Zhang, Congnyu Che, Fu Sun, Yanyu Xiong, Taylor Canady, Brian T Cunningham One of the frontiers in the field of biosensors is the ability to quantify specific target molecules with enough precision to count individual units in a test sample, and to... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 17, 2020 Category: Chemistry Authors: Qinglan Huang Source Type: research

An NMR-compatible microfluidic platform enabling in situ electrochemistry
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Hossein Davoodi, Nurdiana Nordin, Lorenzo Bordonali, Jan Korvink, Neil MacKinnon, Vlad Badilita Combining microfluidic devices with nuclear magnetic resonance (NMR) has the potential of unlocking their vast sample handling and processing operation space for use with the powerful analytics provided by NMR.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 15, 2020 Category: Chemistry Authors: Hossein Davoodi Source Type: research

The Art in Science of MicroTAS 2019
Lab Chip, 2020, Advance Article DOI: 10.1039/D0LC90053B, EditorialGregory A. Cooksey Greg Cooksey (left) and Maria Southall (right) present the Art in Science award to winner Joseph de Rutte at the RSC booth. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 15, 2020 Category: Chemistry Authors: Gregory A. Cooksey Source Type: research

HepaChip-MP – a twenty-four chamber microplate for a continuously perfused liver coculture model
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Marius Busche, Olena Tomilova, Julia Sch ütte, Simon Werner, Meike Beer, Nicola Groll, Britta Hagmeyer, Michael Pawlak, Peter D. Jones, Christian Schmees, Holger Becker, Juliane Schnabel, Karsten Gall, Roland Hemmler, Madlen Matz-Soja, Georg Damm, Simon Beuck, Tobias Klaassen, Jana Moer, Anett Ullrich, Dieter Runge, Katja Schenke-Layland, Rolf Gebhardt, Martin Stelzle HepaChip-MP: a 24-culture-chamber, automated microfluidicin vitro model of the liver sinusoid in multiwellplate format. To cite this article before page numbe...
Source: RSC - Lab Chip latest articles - July 15, 2020 Category: Chemistry Authors: Marius Busche Source Type: research

Recognition and location of motile microorganisms by shape-matching photoluminescence micro-patterns
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00465K, PaperMeng Su, Zhandong Huang, Jing Liu, Yifan Li, Qi Pan, Zeying Zhang, Zheng Li, Zheren Cai, Bingda Chen, Shuoran Chen, Fengyu Li, Yanlin Song The typical dimensions of the bacterial and microorganism cells match well with the scales at which nanomaterials-based architectures can influence the environment. However, it is one of the most formidable... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 13, 2020 Category: Chemistry Authors: Meng Su Source Type: research

Fast Antimicrobial Susceptibility Testing on Escherichia coli by Metabolic Heat Nanocalorimetry
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00579G, PaperYang LIU, Thomas Lehnert, Martin Gijs Fast spreading of antimicrobial resistance is now considered a major global health threat. New technologies are required, enabling rapid diagnostics of bacterial infection combined with fast antimicrobial susceptibility testing (AST)... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 13, 2020 Category: Chemistry Authors: Yang LIU Source Type: research

Centrifugal microfluidic device for high-throughput synthesis of Pd@AuPt core-shell nanoparticles to evaluate the performance of hydrogen peroxide generation
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00461H, PaperHau Van Nguyen, Kiyoon Kim, Hyobin Nam, Seung Yong Lee, Taekyung Yu, Tae Seok Seo We propose a novel high-throughput screening platform using a centrifugal microfluidic device for producing combinatorial tri-metallic catalysts. The centrifugal device was designed to perform sixty reactions under different conditions on... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 13, 2020 Category: Chemistry Authors: Hau Van Nguyen Source Type: research

Amnion-on-a-chip: modeling human amniotic development in mid-gestation from pluripotent stem cells
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00268B, PaperJianhua Qin, Yujuan Zhu, Hui Wang, Fangchao Yin, Yaqiong Guo, Fei Li, Dong Gao Amnion serves to create a protective environment for growing fetus and the study of amniotic development will greatly facilitate our understanding of normal and diseased pregnancy. However, it remains poorly... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 13, 2020 Category: Chemistry Authors: Jianhua Qin Source Type: research

Microfluidic Chips Enabled One-step Synthetization of Biofunctionalized CuInS2/ZnS Quantum Dots
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00202J, PaperSiyi Hu, Butian Zhang, Shuwen Zeng, Liwei Liu, Ken-Tye Yong, Hanbin Ma, Yuguo Tang Biofunctionalized quantum dots (QDs) are effective targeted fluorescent labels for bioimaging. However, conventional synthesis of biofunctionalized I-III-VI core-shell CuInS2/ZnS QDs requires complex bench-top operations, results in limited product performance and... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 13, 2020 Category: Chemistry Authors: Siyi Hu Source Type: research

Enhancement of inflection point focusing and rare-cell separations from untreated whole blood
Lab Chip, 2020, Advance Article DOI: 10.1039/D0LC00309C, PaperDongwoo Lee, Yo-han Choi, Wonhee Lee Inertial lift force towards inflection points is enhanced by the combined effect of U-shape channel and co-flow, which enables unprecedented high-throughput cell separations from untreated whole blood. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 10, 2020 Category: Chemistry Authors: Dongwoo Lee Source Type: research

Polymorphic calcium alginate microfibers assembled using programmable microfluidic field for cell regulation
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00517G, PaperQiwei Huang, Yingyi Li, Longfei Fan, John Xin, Hui Yu, Dongdong Ye Effectively guiding and accurately controlling cell adhesion and growth on the surface of specific morphological materials are key issues and hot research directions for optimizing biomaterials. Herein, novel polymorphic alginate... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 10, 2020 Category: Chemistry Authors: Qiwei Huang Source Type: research

OSTE+ for in-situ SAXS Analysis with Droplet Microfluidic Devices
Lab Chip, 2020, Accepted Manuscript DOI: 10.1039/D0LC00454E, PaperTobias Lange, Sophie Charton, Thomas Bizien, Fabienne Testard, Florent Malloggi In recent years, microfluidic-based sample preparation techniques have emerged as a powerful tool for measurements at large scale X-ray facilities. Most often the microfluidic device was a form of hybrid... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - July 8, 2020 Category: Chemistry Authors: Tobias Lange Source Type: research