Detection and Identification of Single Ribonucleotide Monophosphates using a Dual In-Plane Nanopore Sensor Made from a Thermoplastic via Replication
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Steven A. Soper, Chathurika Rathnayaka, Indu Chandrasoma, Junseo Choi, Katie Childers, Maximillian Chibuike, Khurshed Akabirov, Farhad Shiri, Adam R Hall, Collin J McKinney, Matthew David Verber, Sunggook Park We report the generation of ~8 nm dual in-plane pores fabricated in a thermoplastic via nanoimprint lithography (NIL). These pores were connected in series with nanochannels, one of which served... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 10, 2024 Category: Chemistry Authors: Steven A. Soper Source Type: research

A point-of-care testing platform for on-site identification of genetically modified crops
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00040D, PaperYangyang Wang, Furui Yang, Yingyi Fu, Xin He, Haowei Tian, Lili Yang, Mengxi Wu, Jijuan Cao, Junshan Liu Genetically modified (GM) food is still highly controversial nowadays. Due to the disparate policies and attitudes worldwide, demands for a rapid, cost-effective and user-friendly GM crops identification method are increasingly... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 10, 2024 Category: Chemistry Authors: Yangyang Wang Source Type: research

Microfluidic Particle Counter Visualizing Mucosal Antibody Levels against SARS-CoV-2 in the Upper Respiratory Tract for Rapid Evaluation of Immune Protection
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Jiaheng Li, Lok Ting CHU, Hogi Hartanto, Guihuan Guo, Lu LIU, Jianpeng WU, Minghui Wu, Chenyu Cui, Gaobo Wang, Wengang LIU, Hoi Kwan Kwong, Siying WU, Ting-Hsuan Chen Mucosal antibodies at the upper respiratory tract are the earliest and most critical responders to prevent respiratory infections, providing an indication to rapidly evaluate immune protection. Here, we report a... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 8, 2024 Category: Chemistry Authors: Jiaheng Li Source Type: research

Dielectrophoretic Characterization and Selection of Non-spherical Flagellate Algae in the Parallel Channels with Right-angle Bipolar Electrodes
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00165F, PaperXiaoming Chen, Shun Liu, Mo Shen, Jishun Shi, Chungang Wu , Zhipeng Song, Yong Zhao Non-spherical flagellate algae play an increasingly significant role in handling problematic issues as versatile biological micro/nanorobots and resources of valuable bioproducts. However, the commensalism of flagellate algae with distinct structures... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 8, 2024 Category: Chemistry Authors: Xiaoming Chen Source Type: research

Spatially controlled diffusion range of tumor-associated angiogenic factors to develop a tumor model using a microfluidic resistive circuit
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00891F, PaperYu-Hsiang Hsu, Wen-Chih Yang, Yi-Ting Chen, Che-Yu Lin, Chiou-Fong Yang, Wei-Wen Liu, Subhashree Shivani, Pai-Chi Li The DC-MPS device uses a velocity V-clamp to create a partition with a steep concentration gradient for simultaneously developing vasculogenic vessels and a tumor. It enables vessel –tumor interaction to develop a tumor model with angiogenic vessels. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 5, 2024 Category: Chemistry Authors: Yu-Hsiang Hsu Source Type: research

Study on the hemodynamic effects of different pulsatile working modes of the rotary blood pump using a microfluidic platform that realizes in-vitro cell culture effectively
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00159A, PaperLixue Liang, Xueying Wang, Dong Chen, Palaniappan Sethu, Guruprasad A. Giridharan, Yanxia Wang, Yu Wang, Kairong Qin Rotary blood pumps (RBP) operating at a constant speed generate non-physiologic blood pressure and flow rate, which can cause endothelial dysfunction, leading to adverse clinical events in peripheral blood vessels... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 5, 2024 Category: Chemistry Authors: Lixue Liang Source Type: research

Piezoelectric and microfluidic tuning of infrared cavity for vibrational polariton studies
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D3LC01101A, PaperWei Wang, Jaime De  La Fuente Diez, Nicolas DELSUC, Juan Peng, Riccardo Spezia, Rodolphe Vuilleumier, Yong Chen We developed a microfluidic system for vibrational polariton studies, which consists of two microfluidic chips: one for solution mixing and another for tuning an infrared cavity made of a pair... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 5, 2024 Category: Chemistry Authors: Wei Wang Source Type: research

Direct Laser Writing-Enabled 3D Printing Strategies for Microfluidic Applications
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Olivia M Young, Xin Xu, Sunandita Sarker, Ryan D Sochol Over the past decade, additive manufacturing —or “three-dimensional (3D) printing”—has attracted increasing attention in the Lab on a Chip community as a pathway to achieve sophisticated system architectures that are difficult... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 4, 2024 Category: Chemistry Authors: Olivia M Young Source Type: research

A microfluidic-based gut-on-a-chip model containing the gut microbiota of patients with depression reveals physiological characteristics similar to depression.
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D3LC01052J, PaperWenxin Wang, Yiyuan Liu, Zhikai Yao, Dengbo Chen, Yue Tang, Jingwei Cui, Jiangjiang Zhang, Hong Liu, Zikai Hao gut microbes, depression, gut-on-a-chip, DoGC,5-HT, inflammation The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 4, 2024 Category: Chemistry Authors: Wenxin Wang Source Type: research

High-throughput viscoelastic characterization of cells in hyperbolic microchannels
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Felix Reichel, Ruchi Goswami, Salvatore Girardo, Jochen Guck Extensive research has demonstrated the potential of cell viscoelastic properties as intrinsic indicators of cell state, functionality, and disease. For this, several microfluidic techniques have been developed to measure cell... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 3, 2024 Category: Chemistry Authors: Felix Reichel Source Type: research

Evaluating thrombosis risk and patient-specific treatment strategy using an atherothrombosis-on-chip model
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00131A, PaperFahima Akther, Hedieh Fallahi, Jun Zhang, Nam-Trung Nguyen, Hang Thu Ta Platelets play an essential role in thrombotic processes. Recent studies suggest a direct link between the increased plasma glucose, lipids, and inflammatory cytokines with platelet activation and aggregation, resulting in... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 2, 2024 Category: Chemistry Authors: Fahima Akther Source Type: research

A surface-engineered contact lens for tear fluid biomolecule sensing
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Aravind M, Sajan D. George Adhesive contrast contact lens fabricated by selective lubricant grafting splits tear film on specified zone by secretion and blinking. Integrating the contact lens with the spectroscopic technique offers an efficient platform for biomolecule sensing. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 2, 2024 Category: Chemistry Authors: Aravind M Source Type: research

Integrated High Performance Microfluidic Organic Analysis Instrument for Planetary and Space Exploration
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00012A, PaperAnna Butterworth, Matin Golozar, Zachary Estlack, Jeremy McCauley, Richard A. Mathies, Jungkyu Kim The exploration of our solar system to characterize the molecular organic inventory will enable the identification of potentially habitable regions and initiate the search for biosignatures of extraterrestrial life. However,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 2, 2024 Category: Chemistry Authors: Anna Butterworth Source Type: research

Investigation of air bubble behavior after gas embolism events induced in a microfluidic network mimicking microvasculature
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D4LC00087K, PaperMohammad Mahdi Mardanpour, Ayyappasamy Sudalaiyadum Perumal, Karine Baassiri, Zahra Mahmoodi, Gala Montiel Rubies, Kenneth LeDez, Dan V Nicolau Gas (or air) embolism is a medical condition caused when gas bubbles are present in venous or arterial blood vessels, leading to limited or blocked blood and oxygen supply to... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - April 2, 2024 Category: Chemistry Authors: Mohammad Mahdi Mardanpour Source Type: research

Development of a self-contained microfluidic chip and an internet-of-things-based point-of-care device for automated identification of respiratory viruses
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Nguyen Quoc Huynh Quoc, Van Dan Nguyen, Vu Minh Phan, Tae Seok Seo The COVID-19 pandemic greatly impacted the in-vitro diagnostic market, leading to the development of new technologies such as point-of-care testing (POCT), multiplex testing, and digital health platforms. In this study,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - March 28, 2024 Category: Chemistry Authors: Nguyen Quoc Huynh Quoc Source Type: research