Progress in developing microphysiological systems for biological product assessment
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Mona Mansouri, Johnny Lam, Kyung E. Sung This review delves into microphysiological systems, miniature physiological environments used to evaluate biological products, reducing the need for animal experimentation. We consider their benefits as well as persistent challenges in material selection/fabrication and reproducibility. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 17, 2024 Category: Chemistry Authors: Mona Mansouri Source Type: research
Centrifugal microfluidic system for colorimetric sample-to-answer detection of viral pathogens
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Matthias Geissler, Daniel Brassard, Nadine Adam, Neda Nasheri, Ana Victoria C. Pilar, Kyle Tapp, Liviu Clime, Caroline Miville-Godin, Maxence Mounier, Christina Nassif, Ljuboje Lukic, Lidija Malic, Nathalie Corneau, Teodor Veres Automated on-chip sample-to-answer workflow for multiplexed colorimetric detection of foodborne viruses using an embedded polymer micropillar array for read-out. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society o...
Source: RSC - Lab Chip latest articles - January 16, 2024 Category: Chemistry Authors: Matthias Geissler Source Type: research
Separation of platelets by size in a microfluidic device based on controlled incremental filtration
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC00842H, PaperMai T.P. Dinh, Anton Mukhamedshin, Kumar Abhishek, Fong W. Lam, Sean C. Gifford, Sergey S. Shevkoplyas The significant biological and functional differences between small and large platelets suggested by recent studies could have profound implications for transfusion medicine. However, investigating the relationship between platelet size and... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 16, 2024 Category: Chemistry Authors: Mai T.P. Dinh Source Type: research
Lab-on-chip technologies for exploring the gut –immune axis in metabolic disease
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Alexandra E. Wheeler, Verena Stoeger, R óisín M. Owens Further development of lab-on-chip platforms is required to create an environment capable of hosting more complex microbiota and immune cells. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 16, 2024 Category: Chemistry Authors: Alexandra E. Wheeler Source Type: research
High sensitivity and automatic chemiluminescence detection of glucose and lactate using a spin-disc paper-based device
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00937H, PaperWenqiang Tong, Jiaming Shi, Zhihang Yu, Bin Ran, Huaying Chen, Yonggang Zhu This paper reports a spin-disc paper-based device with 10 individual detection units containing electromagnetic modules controlling the sample incubation time before chemiluminescence (CL) signal detection. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 15, 2024 Category: Chemistry Authors: Wenqiang Tong Source Type: research
Revolutionizing Targeted Precision: Microfluidic-Enabled Smart Microcapsules for Tailored Delivery and Controlled Release
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC00835E, Critical ReviewLingling Ren, Shuang Liu, Junjie Zhong, Liyuan Zhang Smart microcapsules, as promising delivery systems, have garnered significant attention for targeted delivery loaded diverse active materials. By precisely manipulating fluids on the micrometer scale, microfluidic has emerged as a... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 15, 2024 Category: Chemistry Authors: Lingling Ren Source Type: research
The crystal orientation of THF clathrates in nano-confinement by in situ polarized Raman spectroscopy
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00884C, PaperMrityunjay K. Sharma, Xin Ning Leong, Carolyn A. Koh, Ryan L. Hartman Measurement of the local crystal orientation of THF hydrates within anodic aluminum oxide nanopores using microfluidics andin situ polarized Raman spectroscopy. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 12, 2024 Category: Chemistry Authors: Mrityunjay K. Sharma Source Type: research
High-Throughput Microfluidic Systems Accelerated by Artificial Intelligence for Biomedical Applications
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC01012K, Critical ReviewJianhua Zhou, Jianpei Dong, Hongwei Hou, Lu Huang, Jinghong Li High-throughput microfluidic systems are widely used in biomedical fields for tasks like disease detection, drug testing, and material discovery. Despite the great advance in automation and throughput, the large amounts... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 12, 2024 Category: Chemistry Authors: Jianhua Zhou Source Type: research
Enhancing Safety in Small Confined Spaces with Thermal-Triggered Fire-Extinguishing Microcapsules from Microfluidics
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Chen Li, Hairui Bian, Dang Ding, Fangsheng Huang, Zhiqiang Zhu Fires in small confined spaces have problems such as difficulty in extinguishing, fast burning speed, long duration, strong concealment and untimely warning. Perfluorohexanone-based fire extinguishing microcapsule technology provides an important... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 12, 2024 Category: Chemistry Authors: Chen Li Source Type: research
Toward 3D Printed Microfluidic Artificial Lungs for Respiratory Support
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Elyse Fleck, Charlise Keck, Karolina Ryszka, Andrew Zhang, Michael Atie, Sydney Maddox, Joseph Allen Potkay Microfluidic artificial lungs ( µALs) are a new class of membrane oxygenators. Compared to traditional hollow-fiber oxygenators, µALs closely mimic the alveolar microenvironment due to their size-scale and promise improved gas... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 12, 2024 Category: Chemistry Authors: Elyse Fleck Source Type: research
SliceChip: a benchtop fluidic platform for organotypic culture and serial assessment of human and rodent pancreatic slices
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00850A, CommunicationCharles G. Alver, Silvia Álvarez-Cubela, Isabella Altilio, Emily Hutchison, Emma Warrner, Mariana E. Viso, Giana Vitale, David Oliver, Ricardo L. Pastori, Juan Dominguez-Bendala, Ashutosh Agarwal SliceChip maintains perfusion, oxygenation, and bubble free operation for long term culture, imaging, assessment, and recovery of pancreatic slices. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 11, 2024 Category: Chemistry Authors: Charles G. Alver Source Type: research
Survival of P. falciparum infected red blood cell aggregates in elongational shear flow
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00552F, PaperAnna M. J ötten, Anabelle Schepp, Adam Machon, Kirsten Moll, Mats Wahlgren, Timm Krüger, Christoph Westerhausen Rosette “survival” decreases with longer exposure to elongational flow, increases with rosette size and is 5–15% higher in blood group A. The experimental results are substantiated by a simulation of the underlying protein binding kinetics. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 11, 2024 Category: Chemistry Authors: Anna M. J ötten Source Type: research
Multi-step PDMS Curing and Controlled Separation Method for Mass Manufacturing of High-performance and User-Friendly Micro-device: Valved Micropumps
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC00786C, PaperZhichang Du, Wei Sun, Shengli Mi Although valved micropumps have powerful performance, their popularized application is limited by high technical barriers and high costs brought by complex microstructures. Herein, we propose a multi-step PDMS curing method... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 11, 2024 Category: Chemistry Authors: Zhichang Du Source Type: research
A liquid metal based, integrated parallel electroosmotic micropump cluster drive system
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC00926B, PaperQian Li, Pan Zhang, ZI YE, Huimin Zhang, Xiao Sun, Lin Gui The application of liquid metal in a microfluidic system enables the fabrication of highly integrated on-chip electroosmotic micropumps (EOPs). In this work, a low-voltage driveable integrated parallel EOP cluster drive... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 11, 2024 Category: Chemistry Authors: Qian Li Source Type: research
Smart salt-responsive thread for highly sensitive microfluidic glucose detection in sweat
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00975K, PaperLiang Wu, Jing Xiong, Gang Xiao, Jun Ju, Wei Sun, Wei Wang, Yan Ma, Ruilong Ran, Yan Qiao, Changming Li, Ling Yu, Zhisong Lu We prepared a zwitterionic polymer-modified thread with superior hydrophilicity, large water-absorbing capacity, and salt-responsive behaviors for highly sensitive microfluidic glucose detection in sweat. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 10, 2024 Category: Chemistry Authors: Liang Wu Source Type: research
