SARS-CoV-2-induced disruption of a vascular bed in a microphysiological system caused by type-I interferon from bronchial organoids
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Kazuya Fujimoto, Yoshikazu Kameda, Yuta Nagano, Sayaka Deguchi, Takuya Yamamoto, Rafa ł Przybysław Król, Peter Gee, Yasufumi Matsumura, Toru Okamoto, Miki Nagao, Kazuo Takayama, Ryuji Yokokawa Blood vessels show various COVID-19-related conditions including thrombosis and cytokine propagation. Existing in vitro blood vessel models cannot represent the consequent changes in the vascular structure or determine the initial... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 9, 2024 Category: Chemistry Authors: Kazuya Fujimoto Source Type: research

Understanding organotropism in cancer metastasis using microphysiological systems
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00889D, Critical ReviewJihoon Ko, Jiyoung Song, Yedam Lee, Nakwon Choi, Hong Nam Kim Organotropism is an important concept to explain the process of cancer metastasis. In this paper, we introduce microphysiological systems with simultaneous physiological relevance and high throughput to recapitulate the series of cancer progression. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 9, 2024 Category: Chemistry Authors: Jihoon Ko Source Type: research

Label-free cells classification in holographic flow cytometry through unbiased learning strategy
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Gioele Ciaparrone, Daniele Pirone, Pierpaolo Fiore, Lu Xin, Wen Xiao, Xiaoping Li, Francesco Bardozzo, Vittorio Bianco, Lisa Miccio, Feng Pan, Pasquale Memmolo, Roberto Tagliaferri, Pietro Ferraro Nowadays, label-free Imaging flow cytometry at single-cell level is considered the stepforward lab-on-a-chip technology to address challenges in clinical diagnostics, biology, life sciences and healthcare. In this framework, digital holography... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 9, 2024 Category: Chemistry Authors: Gioele Ciaparrone Source Type: research

Angio-Net: deep learning-based label-free detection and morphometric analysis of in vitro angiogenesis
This study introduces Angio-Net, which integrates a high-throughput 3D cell culture device, large-scale image data generation, and deep learning-based virtual staining. The system demonstrated fast and accurate quantitative analysis of complex angiogenesis. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 9, 2024 Category: Chemistry Authors: Suryong Kim Source Type: research

Quantifying neutrophil extracellular trap release in a combined infection –inflammation NET-array device
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Udaya Sree Datla, Bhaskar Vundurthy, Jessica S. Hook, Nidhi Menon, Hossein Razmi Bagtash, Tarik Shihabeddin, David W. Schmidtke, Jessica G. Moreland, Marko Z. Radic, Caroline N. Jones We present a neutrophil extracellular trap (NET)-array device, engineered to quantify the spatiotemporal dynamics of NET release with single-cell resolution in varied microenvironments simulating infection and inflammation. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Societ...
Source: RSC - Lab Chip latest articles - January 8, 2024 Category: Chemistry Authors: Udaya Sree Datla Source Type: research

SliceChip: Benchtop Fluidic Platform for Organotypic Culture and Serial Assessment of Human and Rodent Pancreatic Slices
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC00850A, CommunicationCharles Garcia Alver, Silvia Alvarez-Cubela, Isabella Altilio, Emily Hutchison, Emma Warrner, Mariana Viso, Giana Vitale, David Oliver, Ricardo Pastori, Juan Dominguez-Bendala, Ashutosh Agarwal Enzymatically isolated pancreatic islets are the most commonly used ex vivo testbeds for diabetes research. Recently, precision-cut living slices of human pancreas are emerging as an exciting alternative because they... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 8, 2024 Category: Chemistry Authors: Charles Garcia Alver Source Type: research

Rapid cell isolation in breastmilk in a non-clinical setting by a deterministic lateral displacement device and selective water and fat absorption
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00899A, PaperJamar Hawkins, Eva P. Browne, Kathleen F. Arcaro, Yubing Sun We developed a workflow to concentrate rare breast cells from breastmilk by deterministic lateral displacement devices and water/oil absorbing beads. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 8, 2024 Category: Chemistry Authors: Jamar Hawkins Source Type: research

Enabling continuous immune cell recirculation on a microfluidic array to study immunotherapeutic interactions in a recapitulated tumour microenvironment
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00662J, PaperChun-Wei Chi, Yeh-Hsing Lao, A. H. Rezwanuddin Ahmed, Siyu He, Taha Merghoub, Kam W. Leong, Sihong Wang We developed a tumour-on-a-chip system that recapitulated dynamic interplay between immunotherapeutics, regenerated microvessels, tumor stroma and recirculating immune cells. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 5, 2024 Category: Chemistry Authors: Chun-Wei Chi Source Type: research

Correction: Sub-nL thin-film differential scanning calorimetry chip for rapid thermal analysis of liquid samples
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Sheng Ni, Hanliang Zhu, Pavel Neuzil, Levent Yobas To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 5, 2024 Category: Chemistry Authors: Sheng Ni Source Type: research

A continuum model for magnetic particle flows in microfluidics applicable from dilute to packed suspensions
We present a finite-element model for dense magnetic particle flows in microfluidics, employing an interpenetrating continuum approach. It reproduces complex behaviors like aggregation and fluidization, commonly observed phenomena in microfluidics. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 4, 2024 Category: Chemistry Authors: Simon Dumas Source Type: research

Horizontal and vertical microchamber platforms for evaluation of the paracellular permeability of an epithelial cell monolayer
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00855J, PaperRyuya Kida, Mamiko Tsugane, Hiroaki Suzuki Microchamber devices that enable evaluation of paracellular permeability while observing high resolution epithelial cell morphology are developed. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 4, 2024 Category: Chemistry Authors: Ryuya Kida Source Type: research

Expanding CAR-T cell immunotherapy horizons through microfluidics
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00622K, Critical ReviewHyelee Kim, Suyeon Kim, Hyunjung Lim, Aram J. Chung This review outlines Chimeric antigen receptor (CAR)-T cell manufacturing, highlights challenges, and explores successful microfluidic approaches and related technologies to address them. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 4, 2024 Category: Chemistry Authors: Hyelee Kim Source Type: research

AI-enhanced biomedical micro/nanorobots in microfluidics
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00909B, Tutorial ReviewHui Dong, Jiawen Lin, Yihui Tao, Yuan Jia, Lining Sun, Wen Jung Li, Hao Sun Although developed independently at the beginning, AI, micro/nanorobots and microfluidics have become more intertwined in the past few years which has greatly propelled the cutting-edge development in fields of biomedical sciences. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 4, 2024 Category: Chemistry Authors: Hui Dong Source Type: research

Multifunctional droplet handling on surface-charge-graphic-decorated porous papers
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00806A, PaperJiayao Wu, Duokui Fang, Yifan Zhou, Ge Gao, Ji Zeng, Yubin Zeng, Huai Zheng Surface charge graphics endow unspecific porous papers with multifunctional droplet manipulation, which shows great potential for applications in flexible droplet pick-up robots and dynamically controllable fluidic networks. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 4, 2024 Category: Chemistry Authors: Jiayao Wu Source Type: research

Centrifugal microfluidic lab-on-a-chip system for colorimetric sample-to-answer detection of viral pathogens
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Matthias Geissler, Daniel Brassard, Nadine Adam, Nead Nasheri, Ana Victoria Pilar, Kyle Tapp, Liviu Clime, Caroline Miville-Godin, Maxence Mounier, Christina Nassif, Ljuboje Lukic, Lidija Malic, Nathalie Corneau, Teodor Veres The development of technologies for rapid, automated detection of viral pathogens is key for regulatory agencies to shorten response times in food safety surveillance, compliance, and enforcement as well as... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - January 4, 2024 Category: Chemistry Authors: Matthias Geissler Source Type: research