On-chip droplet analysis and cell spheroid screening by capillary wrapping enabled shape-adaptive ferrofluid transporters
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Xuejiao Wang, Xin Li, Aoyang Pu, Ho Bak Shun, Cien Chen, Liqing Ai, Zhaoling Tan, Jilin Zhang, Kai Liu, Jun Gao, Kiwon Ban, Xi Yao We propose a ferrofluid transporter for digital droplet manipulation in an additive-free and lossless manner. The transporter shows high reliability with an on-chip design for droplet-based bioanalysis and high throughput cell spheroid screening. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (...
Source: RSC - Lab Chip latest articles - February 15, 2024 Category: Chemistry Authors: Xuejiao Wang Source Type: research
Open microfluidics: droplet microarrays as next generation multiwell plates for high throughput screening
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Robert Strutt, Bijing Xiong, Vanessa Fabienne Abegg, Petra S. Dittrich Droplet microarrays underpin novel experimentation across the biological and chemical sciences. This perspective explores operations and analysis with droplet microarrays, placing focus on a comparison to traditional multiwell plates. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 15, 2024 Category: Chemistry Authors: Robert Strutt Source Type: research
Nanoscale sorting of extracellular vesicles via optically-induced dielectrophoresis on an integrated microfluidic system
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC01007D, PaperWei-Jen Soong, Chih-Hung Wang, Chihchen Chen, Gwo-Bin Lee We devised an innovative method for automated sorting of extracellular vesicles (EVs) employing optically-induced dielectrophoresis on an integrated microfluidic chip. EVs of three distinct size categories could be isolated in 1 h at a purity of 86%. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 15, 2024 Category: Chemistry Authors: Wei-Jen Soong Source Type: research
Integrated phase separation in microliter droplets for ultratrace-enriching biomarker analysis
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00953J, PaperQihao Zha, Yong Luo, Conghui Liu, Tailin Xu An ultratrace microRNA detection platform that combines a minipillar array with an aqueous two-phase system to achieve a significant increase in target concentration in microliter droplets. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 15, 2024 Category: Chemistry Authors: Qihao Zha Source Type: research
Confining calcium oxalate crystal ’s growth in carbonated apatite-coated microfluidic channel to better understand the role of Randall’s plaque in kidney stone formation
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC01050C, PaperSamantha Bourg, Karol Rakotozandriny, Ivan Lucas, Emmanuel Letavernier, Christian Bonhomme, Florence Babonneau, Ali Abou-Hassan Effective prevention of recurrent kidney stone ’s diseases requires the understanding of their mechanisms of formation. Numerous in vivo observations have demonstrated that a large number of pathological calcium oxalate kidney... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 15, 2024 Category: Chemistry Authors: Samantha Bourg Source Type: research
Enhanced acoustic streaming effects via sharp-edged 3D microstructures
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00742A, PaperWilliam S. Harley, Kirill Kolesnik, Daniel E. Heath, David J. Collins The use of 3D sharp-edged microstructures enhances the versatility of sharp-edge driven microstreaming, with control over the magnitude and orientation of streaming vortexes for targeted particle microfluidic manipulation. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 15, 2024 Category: Chemistry Authors: William S. Harley Source Type: research
From animal testing to in vitro systems: advancing standardization in microphysiological systems
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC00994G, PerspectiveDarwin R. Reyes, Mandy Brigitte Esch, Ewart Lorna, Rohollah Nasiri, Anna Herland, Kyung E Sung, Monica Piergiovanni, Carolina Lucchesi, Jelena Vukasinovic, James T. Shoemaker, Hiroki Nakae, James Hickman, Kapil Pant, Anne Marion Taylor, Niki Heinz, Nureddin Ashammakhi Limitations with cell cultures and experimental animal-based studies have had the scientific and industrial communities searching for new approaches that can provide reliable human models for applications such as drug... The content of this RSS Feed (c) The Royal Society of Chemistry (Sou...
Source: RSC - Lab Chip latest articles - February 15, 2024 Category: Chemistry Authors: Darwin R. Reyes Source Type: research
A Microfluidic Chip for Sustained Oxygen Gradient Formation in the Intestine Ex Vivo
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC00793F, PaperLauren M Delong, Colby E Witt, Madison Pennell, Ashley E. Ross The oxygen gradient across the intestine influences intestinal physiology and the microbial environment of the microbiome. The microbiome releases metabolites that communicate with enterochromaffin cells, neuronal cells, and resident immune... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 15, 2024 Category: Chemistry Authors: Lauren M Delong Source Type: research
A dual-functional microfluidic chip for guiding personalized lung cancer medicine: combining EGFR mutation detection and organoid-based drug response test
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00974B, PaperKexin Zhang, Jiyu Xi, Huiting Zhao, Yadong Wang, Jianchao Xue, Naixin Liang, Zewen Wei The RDMO-Chip combines rapid EGFR mutation detection and organoid-based drug response test for guiding personalized lung cancer medicine. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 14, 2024 Category: Chemistry Authors: Kexin Zhang Source Type: research
Lab-on-a-chip models of the blood –brain barrier: evolution, problems, perspectives
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00996C, PerspectiveM ária A. Deli, Gergő Porkoláb, András Kincses, Mária Mészáros, Anikó Szecskó, Anna E. Kocsis, Judit P. Vigh, Sándor Valkai, Szilvia Veszelka, Fruzsina R. Walter, András Dér A great progress has been made in the development and use of lab-on-a-chip devices to model and study the blood –brain barrier (BBB) in the last decade. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 14, 2024 Category: Chemistry Authors: M ária A. Deli Source Type: research
A flexible electrode Array for genetic transfection of different layers of the retina by electroporation
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC01014G, PaperYu Zhang, Tao Peng, Yu Ge, Mengda Li, Chendi Li, Jiyu Xi, Zixi Li, Zewen Wei, Yuntao Hu Stratified delivery into specific retinal layers was realized by a flexible electrode array that exhibited high compatibility with surgical procedures. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 14, 2024 Category: Chemistry Authors: Yu Zhang Source Type: research
A microphysiological system for parallelized morphological and electrophysiological read-out of 3D neuronal cell culture
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00963G, PaperPeter D. Jones, Beatriz Molina-Mart ínez, Anita Niedworok, Paolo Cesare Electrophysiology of 3D neural cultures: our multilayer microfluidics on glass microelectrode arrays enable parallel analysis of compartmentalized 3D neural models, with applications in neurology, pharmacology research and substance testing. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 13, 2024 Category: Chemistry Authors: Peter D. Jones Source Type: research
Integrated phase separation in microliter droplets for ultratrace-enriching biomarker analysis
In this study, we have developed an enrichment detection platform by combining a minipillar array... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 13, 2024 Category: Chemistry Authors: Qihao Zha Source Type: research
A miniprotein receptor electrochemical biosensor chip based on quantum dot
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC01100C, PaperYunong Zhao, Juan Han, Jing Huang, Qing Huang, Yanbing Tao, Ruiqin Gu, Huayao Li, Yang Zhang, Houjin Zhang, Huan Liu Recently protein binders have emerged as a promising substitute for antibodies due to their high specificity and low cost. Herein, we demonstrate an electrochemical biosensor chip through the electronic labelling... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 12, 2024 Category: Chemistry Authors: Yunong Zhao Source Type: research
Microfluidic approaches in microbial ecology
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Giovanni Stefano Ugolini, Miaoxiao Wang, Eleonora Secchi, Roberto Pioli, Martin Ackermann, Roman Stocker Here we explore the use of microfluidic systems in microbial ecology, describing applications ranging from the investigation of single-cell behaviors to the imaging of complex three-dimensional biofilms. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 12, 2024 Category: Chemistry Authors: Giovanni Stefano Ugolini Source Type: research
