A microfluidic chip for sustained oxygen gradient formation in the intestine ex vivo
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00793F, PaperLauren M. Delong, Colby E. Witt, Madison Pennell, Ashley E. Ross Here, we have developed a 3D printed microfluidic device capable of oxygen gradient formation within intestinal tissue slicesex vivo. The device is open-welled and compatible with external electrochemical recording during tissue analysis. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 19, 2024 Category: Chemistry Authors: Lauren M. Delong Source Type: research
A miniprotein receptor electrochemical biosensor chip based on quantum dots
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC01100C, PaperYunong Zhao, Juan Han, Jing Huang, Qing Huang, Yanbing Tao, Ruiqin Gu, Hua-Yao Li, Yang Zhang, Houjin Zhang, Huan Liu We developed an on-chip laboratory for biomolecule interactions and kinetics analysis based on the three-electrode and high electron mobility transistor (HEMT) chip platform. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 19, 2024 Category: Chemistry Authors: Yunong Zhao Source Type: research
Test strip coupled Cas12a-assisted signal amplification strategy for sensitive detection of uracil-DNA glycosylase
In this study, we employed Cas12a protein and enzyme-assisted cycle amplification technology with a test strip to establish a precise platform for the detection of UDG enzyme. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 19, 2024 Category: Chemistry Authors: Bin Guo Source Type: research
From animal testing to in vitro systems: advancing standardization in microphysiological systems
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00994G, PerspectiveDarwin R. Reyes, Mandy B. Esch, Lorna Ewart, Rohollah Nasiri, Anna Herland, Kyung Sung, Monica Piergiovanni, Carolina Lucchesi, James T. Shoemaker, Jelena Vukasinovic, Hiroki Nakae, James Hickman, Kapil Pant, Anne Taylor, Niki Heinz, Nureddin Ashammakhi For MPS technology to be effective not only innovation but standardization will be vital. This will require the consensus of all interested parties including academics, developers, regulatory agencies, metrology institutions, and stakeholders. To cite this article before page numbers are assigned, use the D...
Source: RSC - Lab Chip latest articles - February 19, 2024 Category: Chemistry Authors: Darwin R. Reyes Source Type: research
Microfluidic systems for infectious disease diagnostics
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Thomas Lehnert, Martin A. M. Gijs This review explores emerging microfluidic-based technologies incorporating innovative assay strategies for infectious disease diagnostics. Our classification scheme is based on the human body systems or pathogen transmission modes. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 19, 2024 Category: Chemistry Authors: Thomas Lehnert Source Type: research
A Microfluidic Impedance Cytometry with Flat-end Cylindrical Electrodes for Accurate and Fast Analysis of Marine Microalgae
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D3LC00942D, PaperXiaoming Chen, Mo Shen, Shun Liu, Chungang Wu , Liangliang Sun, Zhipeng Song, Jishun Shi, Yulong Yuan, Yong Zhao Marine microalgae play an increasingly significant role in addressing the issues of environmental monitoring and disease treatment, enabling analysis of marine microalgae at the single-cell level an essential technique. For... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 19, 2024 Category: Chemistry Authors: Xiaoming Chen Source Type: research
A system for fluid pumping by liquid metal multi-droplets
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC01017A, PaperLiyu Dai, Xiaomin Wu, Huimin Hou, Zhifeng Hu, Yukai Lin, Zhiping Yuan Cuboid pump systems driven by liquid metal multi-droplets using pillars to restrain the motion of droplets are designed, which achieve a significant increase in the flow rate of the pump. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 19, 2024 Category: Chemistry Authors: Liyu Dai Source Type: research
Multifunctional cardiac microphysiological system based on transparent ITO electrodes for simultaneous optical measurement and electrical signal monitoring
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D3LC00908D, PaperZhangjie Li, Kai Niu, Chenyang Zhou, Feifan Wang, Kangyi Lu, Yijun Liu, Lian Xuan, Xiaolin Wang Drug-induced cardiotoxicity is a significant contributor to drug recalls, primarily attributed to limitations in existing drug screening platforms. Traditional heart-on-a-chip platforms often employ metallic electrodes to record cardiomyocyte electrical signals.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 19, 2024 Category: Chemistry Authors: Zhangjie Li Source Type: research
A multifunctional flexible magnetic drive gripper for target manipulation in complex constrained environments
Lab Chip, 2024, Accepted Manuscript DOI: 10.1039/D3LC00945A, PaperMeiying Zhao, Ye Tao, Wenshang Guo, Zhenyou Ge, Hanqing Hu, Ying Yan, Chaoxia Zou, Guiyu Wang, Yukun Ren Soft actuators capable of remote-controlled guidance and manipulation within complex constrained spaces hold great promise in various fields, especially in medical fields such as minimally invasive surgery. However, most current... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 19, 2024 Category: Chemistry Authors: Meiying Zhao Source Type: research
Gravity-perfused airway-on-a-chip optimized for quantitative BSL-3 studies of SARS-CoV-2 infection: barrier permeability, cytokine production, immunohistochemistry, and viral load assays
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Shannon L. Faley, Niloufar A. Boghdeh, David K. Schaffer, Eric C. Spivey, Farhang Alem, Aarthi Narayanan, John P. Wikswo, Jacquelyn A. Brown Gravity-perfused, air –liquid interface airway chip optimized for BSL-3 infectious disease studies with rapid physiological function testing and high throughput. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 16, 2024 Category: Chemistry Authors: Shannon L. Faley Source Type: research
Immune cells and inflammatory mediators cause endothelial dysfunction in a vascular microphysiological system
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC00824J, PaperAishwarya Rengarajan, Hannah E. Goldblatt, David J. Beebe, Mar ía Virumbrales-Muñoz, Derek S. Boeldt Functional assessment of endothelium serves as an important indicator of vascular health and is compromised in vascular disorders including hypertension, atherosclerosis, and preeclampsia. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 16, 2024 Category: Chemistry Authors: Aishwarya Rengarajan Source Type: research
Assessing bioartificial organ function: the 3P model framework and its validation
Lab Chip, 2024, Advance Article DOI: 10.1039/D3LC01020A, PaperJingmin An, Shuyu Zhang, Juan Wu, Haolin Chen, Guoshi Xu, Yifan Hou, Ruoyu Liu, Na Li, Wenjuan Cui, Xin Li, Yi Du, Qi Gu The 3P framework for liver models utilizes machine learning to enhance precision, personalization, and prediction in assessing liver functions, representing a significant advancement in the field of bioartificial organ research. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 16, 2024 Category: Chemistry Authors: Jingmin An Source Type: research
AMF-SporeChip provides new insights into arbuscular mycorrhizal fungal asymbiotic hyphal growth dynamics at the cellular level.
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Felix Richter, Maryline Calonne-Salmon, Marcel Van der Heijden, St éphane Declerck, Claire Elizabeth Stanley Arbuscular mycorrhizal fungi (AMF) form symbiotic associations with the majority of land plants and deliver a wide range of soil-based ecosystem services. Due to their conspicuous belowground lifestyle in a... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 16, 2024 Category: Chemistry Authors: Felix Richter Source Type: research
On-chip droplet analysis and cell spheroid screening by capillary wrapping enabled shape-adaptive ferrofluid transporters
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Xuejiao Wang, Xin Li, Aoyang Pu, Ho Bak Shun, Cien Chen, Liqing Ai, Zhaoling Tan, Jilin Zhang, Kai Liu, Jun Gao, Kiwon Ban, Xi Yao We propose a ferrofluid transporter for digital droplet manipulation in an additive-free and lossless manner. The transporter shows high reliability with an on-chip design for droplet-based bioanalysis and high throughput cell spheroid screening. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (...
Source: RSC - Lab Chip latest articles - February 15, 2024 Category: Chemistry Authors: Xuejiao Wang Source Type: research
Open microfluidics: droplet microarrays as next generation multiwell plates for high throughput screening
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Robert Strutt, Bijing Xiong, Vanessa Fabienne Abegg, Petra S. Dittrich Droplet microarrays underpin novel experimentation across the biological and chemical sciences. This perspective explores operations and analysis with droplet microarrays, placing focus on a comparison to traditional multiwell plates. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Lab Chip latest articles)
Source: RSC - Lab Chip latest articles - February 15, 2024 Category: Chemistry Authors: Robert Strutt Source Type: research
