GSE150356 Expression data from SUN2 downstream
In this study, we used the microarray to indentify the dnownstream of SUN2 in HCT116 after knocking down SUN2. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - May 15, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research

P19-derived neuronal cells express H < sub > 1 < /sub > , H < sub > 2 < /sub > , and H < sub > 3 < /sub > histamine receptors: a biopharmaceutical approach to evaluate antihistamine agents
This report aimed to characterize the response of neurons differentiated from mouse P19 embryonal carcinoma cells to histamine treatment, and to investigate the modulation of this response by antihistamine drugs, vegetal diamine oxidase, and catalase. The exposure of P19 neurons to histamine reduced cell viability to 65% maximally. This effect involves specific histamine receptors, since it was prevented by treatment with desloratadine and cimetidine, respectively, H1 and H2 antagonists, but not by the H3 antagonist ciproxifan. RT-PCR analysis showed that P19 neurons express H1 and H2 receptors, and the H3 receptor, althou...
Source: Amino Acids - May 12, 2023 Category: Biochemistry Authors: Mariela Gomez Perez Georgiana Tanasie Armelle Tchoumi Neree Narjara Gonzalez Suarez Clara Lafortune Joanne Paquin Lucia Marcocci Paola Pietrangeli Borhane Annabi Mircea Alexandru Mateescu Source Type: research

P19-derived neuronal cells express H < sub > 1 < /sub > , H < sub > 2 < /sub > , and H < sub > 3 < /sub > histamine receptors: a biopharmaceutical approach to evaluate antihistamine agents
This report aimed to characterize the response of neurons differentiated from mouse P19 embryonal carcinoma cells to histamine treatment, and to investigate the modulation of this response by antihistamine drugs, vegetal diamine oxidase, and catalase. The exposure of P19 neurons to histamine reduced cell viability to 65% maximally. This effect involves specific histamine receptors, since it was prevented by treatment with desloratadine and cimetidine, respectively, H1 and H2 antagonists, but not by the H3 antagonist ciproxifan. RT-PCR analysis showed that P19 neurons express H1 and H2 receptors, and the H3 receptor, althou...
Source: Amino Acids - May 12, 2023 Category: Biochemistry Authors: Mariela Gomez Perez Georgiana Tanasie Armelle Tchoumi Neree Narjara Gonzalez Suarez Clara Lafortune Joanne Paquin Lucia Marcocci Paola Pietrangeli Borhane Annabi Mircea Alexandru Mateescu Source Type: research

P19-derived neuronal cells express H < sub > 1 < /sub > , H < sub > 2 < /sub > , and H < sub > 3 < /sub > histamine receptors: a biopharmaceutical approach to evaluate antihistamine agents
This report aimed to characterize the response of neurons differentiated from mouse P19 embryonal carcinoma cells to histamine treatment, and to investigate the modulation of this response by antihistamine drugs, vegetal diamine oxidase, and catalase. The exposure of P19 neurons to histamine reduced cell viability to 65% maximally. This effect involves specific histamine receptors, since it was prevented by treatment with desloratadine and cimetidine, respectively, H1 and H2 antagonists, but not by the H3 antagonist ciproxifan. RT-PCR analysis showed that P19 neurons express H1 and H2 receptors, and the H3 receptor, althou...
Source: Amino Acids - May 12, 2023 Category: Biochemistry Authors: Mariela Gomez Perez Georgiana Tanasie Armelle Tchoumi Neree Narjara Gonzalez Suarez Clara Lafortune Joanne Paquin Lucia Marcocci Paola Pietrangeli Borhane Annabi Mircea Alexandru Mateescu Source Type: research

P19-derived neuronal cells express H < sub > 1 < /sub > , H < sub > 2 < /sub > , and H < sub > 3 < /sub > histamine receptors: a biopharmaceutical approach to evaluate antihistamine agents
This report aimed to characterize the response of neurons differentiated from mouse P19 embryonal carcinoma cells to histamine treatment, and to investigate the modulation of this response by antihistamine drugs, vegetal diamine oxidase, and catalase. The exposure of P19 neurons to histamine reduced cell viability to 65% maximally. This effect involves specific histamine receptors, since it was prevented by treatment with desloratadine and cimetidine, respectively, H1 and H2 antagonists, but not by the H3 antagonist ciproxifan. RT-PCR analysis showed that P19 neurons express H1 and H2 receptors, and the H3 receptor, althou...
Source: Amino Acids - May 12, 2023 Category: Biochemistry Authors: Mariela Gomez Perez Georgiana Tanasie Armelle Tchoumi Neree Narjara Gonzalez Suarez Clara Lafortune Joanne Paquin Lucia Marcocci Paola Pietrangeli Borhane Annabi Mircea Alexandru Mateescu Source Type: research

P19-derived neuronal cells express H < sub > 1 < /sub > , H < sub > 2 < /sub > , and H < sub > 3 < /sub > histamine receptors: a biopharmaceutical approach to evaluate antihistamine agents
This report aimed to characterize the response of neurons differentiated from mouse P19 embryonal carcinoma cells to histamine treatment, and to investigate the modulation of this response by antihistamine drugs, vegetal diamine oxidase, and catalase. The exposure of P19 neurons to histamine reduced cell viability to 65% maximally. This effect involves specific histamine receptors, since it was prevented by treatment with desloratadine and cimetidine, respectively, H1 and H2 antagonists, but not by the H3 antagonist ciproxifan. RT-PCR analysis showed that P19 neurons express H1 and H2 receptors, and the H3 receptor, althou...
Source: Amino Acids - May 12, 2023 Category: Biochemistry Authors: Mariela Gomez Perez Georgiana Tanasie Armelle Tchoumi Neree Narjara Gonzalez Suarez Clara Lafortune Joanne Paquin Lucia Marcocci Paola Pietrangeli Borhane Annabi Mircea Alexandru Mateescu Source Type: research

P19-derived neuronal cells express H < sub > 1 < /sub > , H < sub > 2 < /sub > , and H < sub > 3 < /sub > histamine receptors: a biopharmaceutical approach to evaluate antihistamine agents
This report aimed to characterize the response of neurons differentiated from mouse P19 embryonal carcinoma cells to histamine treatment, and to investigate the modulation of this response by antihistamine drugs, vegetal diamine oxidase, and catalase. The exposure of P19 neurons to histamine reduced cell viability to 65% maximally. This effect involves specific histamine receptors, since it was prevented by treatment with desloratadine and cimetidine, respectively, H1 and H2 antagonists, but not by the H3 antagonist ciproxifan. RT-PCR analysis showed that P19 neurons express H1 and H2 receptors, and the H3 receptor, althou...
Source: Amino Acids - May 12, 2023 Category: Biochemistry Authors: Mariela Gomez Perez Georgiana Tanasie Armelle Tchoumi Neree Narjara Gonzalez Suarez Clara Lafortune Joanne Paquin Lucia Marcocci Paola Pietrangeli Borhane Annabi Mircea Alexandru Mateescu Source Type: research

Outcome and prognostic variables in childhood rhabdomyosarcoma (RMS) with emphasis on impact of FOXO1 fusions in non-metastatic RMS: experience from a tertiary cancer centre in India
Ecancermedicalscience. 2023 Apr 27;17:1539. doi: 10.3332/ecancer.2023.1539. eCollection 2023.ABSTRACTWhile factors influencing outcomes of rhabdomyosarcoma (RMS) in developed countries have evolved from clinical characteristics to molecular profiles, similar data from developing countries are scarce. This is a single-centre analysis of outcomes in treated cases of RMS, with emphasis on prevalence, risk-migration and prognostic impact of Forkhead Box O1 (FOXO1) in non-metastatic RMS. All children with histopathologically proven RMS, treated between January 2013 and December 2018 were included. Intergroup Rhabdomyosarcoma St...
Source: Ecancermedicalscience - May 4, 2023 Category: Cancer & Oncology Authors: Subramaniam Ramanathan Sneha Sisodiya Omshree Shetty Maya Prasad Badira C Parambil Sneha Shah Mukta Ramadwar Nehal Khanna Siddhartha Laskar Sajid Qureshi Tushar Vora Girish Chinnaswamy Source Type: research