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A way to target the Achilles heel of neuroblastoma
(Children's Cancer Institute Australia) Australian scientists have identified a critical molecular 'feedback loop' that helps initiate and drive neuroblastoma, a cancer of the nervous system in children that is triggered in embryonal nerve cells. The research team have also identified an experimental drug, currently in clinical trials for adult cancer, with the potential to interrupt the loop and halt tumor progression. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 4, 2015 Category: Cancer & Oncology Source Type: news

'Breakthrough' may lead to new treatment for fatal childhood cancer
Scientists have discovered an enzyme in the "developmental pathway" of patients with embryonal tumors within multilayers rosettes - an uncommon but deadly childhood brain cancer - which they say may lead to more effective treatment of the disease.The study, published in the journal Nature Genetics, was led by researchers from the Research Institute of the McGill University Health Centre (RI-MUHC), the McGill University and Génome Québec Innovation Centre and The Hospital for Sick Children (SickKids) in Canada. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 17, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

N-cadherin Expression in Germ Cell Tumors of the TestisN-cadherin Expression in Germ Cell Tumors of the Testis
Expression of the transmembrane protein N-cadherin may be useful to differentiate embryonal and chorionic carcinomas from other histological subtypes of testicular germ cell tumors. BMC Clinical Pathology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 18, 2013 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news