Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells
Conditions: Hepatoblastoma; Hepatocellular Carcinoma; Wilms Tumor; Malignant Rhabdoid Tumor; Yolk Sac Tumor; Rhabdomyosarcoma; Liposarcoma; Embryonal Sarcoma of Liver Interventions: Genetic: 21.15.GPC3-CAR T cells Sponsors: Baylor College of Medicine; Center for Cell and Gene Therapy, Baylor College of Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials

External Control, Observational, Retrospective Study Comparing Pralsetinib to Best Available Therapy in Patients With RET-Fusion Positive NSCLC
Conditions:   RET-fusion Non Small Cell Lung Cancer;   Lung Neoplasm;   Carcinoma, Non-Small-Cell Lung;   Respiratory Tract Neoplasms;   Thoracic Neoplasms;   Neoplasms by Site;   Neoplasms;   Lung Diseases;   Respiratory Tract Diseases;   Carcinoma, Bronchogenic;   Bronchial Disea ses;   Head and Neck Neoplasms;   Carcinoma;   Neoplasms by Histologic Type;   Neoplasms, Germ Cell and Embryonal;   Neoplasms, Nerve Tissue;   Metastatic Non Small Cell Lung Cancer Intervention:   Sponsors:   Blueprint Medicines Corporation;   Analysis Group, Inc. Enrolling by invitatio...
Source: ClinicalTrials.gov - January 6, 2021 Category: Research Source Type: clinical trials

Yttrium-90 (TARE-Y90) in Children, Adolescents, and Young Adults With Liver Tumors
Conditions:   Hepatoblastoma;   Hepatocellular Carcinoma;   Rhabdoid Tumor of Liver;   Undifferentiated (Embryonal) Sarcoma of the Liver;   Pediatric Liver Cancer;   Liver Tumors Interventions:   Behavioral: Quality of Life Assessment;   Radiation: Transarterial Radioembolization Sponsors:   Nemours Children's Clinic;   Alfred I. duPont Hospital for Children Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2020 Category: Research Source Type: clinical trials