Genetic and virological characteristics of a reassortant avian influenza A H6N1 virus isolated from wild birds at a live-bird market in Egypt
We examined the replication of kinetics of this virus in different mammalian cell lines (A549, MDCK, and Vero cells) and compared its pathogenicity to that of the ancestral H6N1 virus A/Quail/HK/421/2002(H6N1). The Egyptian H6N1 virus replicated efficiently in C57BL/6 mice without prior adaptation and grew faster and reached higher titers than in A549 cells than the ancestral strain. These results show that reassortant H6 AIVs might pose a potential threat to human health and highlight the need to continue surveillance of H6 AIVs circulating in nature. (Source: Archives of Virology)
Source: Archives of Virology - April 9, 2024 Category: Virology Source Type: research

Spectrum of Genital and Extragenital Anomalies in Malformation Syndromes Associated With 46, XY Disorders of Sex Development: A Single Center Experience
CONCLUSIONS: Integration between clinical, laboratory and genetic data is the cornerstone in the management of XY DSD patients for appropriate decision making of surgical intervention and sex assignment, in addition to screening for other associated features of each mutation.PMID:38584411 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Shaymaa Raafat Yasmine Abdelmeguid Mostafa Kotb Ahmed Oshiba Source Type: research

The association of FSCN1 (rs852479, rs1640233) and HOTAIR (rs920778) polymorphisms with the risk of breast cancer in Egyptian women
CONCLUSIONS: Based on the sample size and genetic characteristics of the subjects involved in the present study, our findings indicated that FSCN1 rs852479 may contribute to BC susceptibility in a sample of the Egyptian population.PMID:38587571 | DOI:10.1007/s11033-024-09459-9 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 8, 2024 Category: Molecular Biology Authors: Eman Reda Galal Dina A Abdelhakam Lamiaa Khalaf Ahmed Yasmine Elhusseny Sherif El Prince Sayed Noha H Eltaweel Source Type: research

Plague and the Mongol conquest of Baghdad (1258)? A reevaluation of the sources
Med Hist. 2024 Apr 8:1-19. doi: 10.1017/mdh.2023.38. Online ahead of print.ABSTRACTThis paper reexamines the sources used by N. Fancy and M.H. Green in "Plague and the Fall of Baghdad (1258)" (Medical History, 65/2 (2021), 157-177). Fancy and Green argued that the Arabic and Persian descriptions of the Mongol sieges in Iran and Iraq, and in particular, in the conquest of Baghdad in 1258, indicate that the besieged fortresses and cities were struck by Plague after the Mongol sieges were lifted. This, they suggested, is part of a recurrent pattern of the outbreak of Plague transmitted by the Mongol expansion across Eurasia. ...
Source: Medical History - April 8, 2024 Category: History of Medicine Authors: Jonathan Brack Michal Biran Reuven Amitai Source Type: research

The effect of significant weight loss after bariatric surgery on echocardiographic indices: an observational study focusing on left ventricular deformation by 2D speckle echocardiography and right ventricular size
CONCLUSIONS: Bariatric surgery could enhance cardiac function, as proven by 2D speckle echocardiography. Changes in RV size may be related to weight loss and should be considered when assessing patients who have undergone bariatric surgery.PMID:38587759 | DOI:10.1186/s43044-024-00474-6 (Source: Atherosclerosis)
Source: Atherosclerosis - April 8, 2024 Category: Cardiology Authors: Saeed Safari Mozhgan Parsaee Mohammad Moradi Mahdi Hakiminejad Parisa Koohsari Farnoosh Larti Source Type: research

Spectrum of Genital and Extragenital Anomalies in Malformation Syndromes Associated With 46, XY Disorders of Sex Development: A Single Center Experience
CONCLUSIONS: Integration between clinical, laboratory and genetic data is the cornerstone in the management of XY DSD patients for appropriate decision making of surgical intervention and sex assignment, in addition to screening for other associated features of each mutation.PMID:38584411 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Shaymaa Raafat Yasmine Abdelmeguid Mostafa Kotb Ahmed Oshiba Source Type: research

The association of FSCN1 (rs852479, rs1640233) and HOTAIR (rs920778) polymorphisms with the risk of breast cancer in Egyptian women
CONCLUSIONS: Based on the sample size and genetic characteristics of the subjects involved in the present study, our findings indicated that FSCN1 rs852479 may contribute to BC susceptibility in a sample of the Egyptian population.PMID:38587571 | PMC:PMC11001669 | DOI:10.1007/s11033-024-09459-9 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 8, 2024 Category: Molecular Biology Authors: Eman Reda Galal Dina A Abdelhakam Lamiaa Khalaf Ahmed Yasmine Elhusseny Sherif El Prince Sayed Noha H Eltaweel Source Type: research

Plague and the Mongol conquest of Baghdad (1258)? A reevaluation of the sources
Med Hist. 2024 Apr 8:1-19. doi: 10.1017/mdh.2023.38. Online ahead of print.ABSTRACTThis paper reexamines the sources used by N. Fancy and M.H. Green in "Plague and the Fall of Baghdad (1258)" (Medical History, 65/2 (2021), 157-177). Fancy and Green argued that the Arabic and Persian descriptions of the Mongol sieges in Iran and Iraq, and in particular, in the conquest of Baghdad in 1258, indicate that the besieged fortresses and cities were struck by Plague after the Mongol sieges were lifted. This, they suggested, is part of a recurrent pattern of the outbreak of Plague transmitted by the Mongol expansion across Eurasia. ...
Source: Medical History - April 8, 2024 Category: History of Medicine Authors: Jonathan Brack Michal Biran Reuven Amitai Source Type: research

Spectrum of Genital and Extragenital Anomalies in Malformation Syndromes Associated With 46, XY Disorders of Sex Development: A Single Center Experience
CONCLUSIONS: Integration between clinical, laboratory and genetic data is the cornerstone in the management of XY DSD patients for appropriate decision making of surgical intervention and sex assignment, in addition to screening for other associated features of each mutation.PMID:38584411 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Shaymaa Raafat Yasmine Abdelmeguid Mostafa Kotb Ahmed Oshiba Source Type: research

The association of FSCN1 (rs852479, rs1640233) and HOTAIR (rs920778) polymorphisms with the risk of breast cancer in Egyptian women
CONCLUSIONS: Based on the sample size and genetic characteristics of the subjects involved in the present study, our findings indicated that FSCN1 rs852479 may contribute to BC susceptibility in a sample of the Egyptian population.PMID:38587571 | PMC:PMC11001669 | DOI:10.1007/s11033-024-09459-9 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 8, 2024 Category: Molecular Biology Authors: Eman Reda Galal Dina A Abdelhakam Lamiaa Khalaf Ahmed Yasmine Elhusseny Sherif El Prince Sayed Noha H Eltaweel Source Type: research