Efficacy and Toxicity of Vincristine and CYP3A5 Genetic Polymorphism in Rhabdomyosarcoma Pediatric Egyptian Patients
CONCLUSION: CYP3A5*1/*1 have less severe vincristine-induced neuropathy than CYP3A5 *1/*3, CYP3A5 *1/*6 and CYP3A5 *3/*3, CYP3A5 *3/*6. There is a significant influence of CYP3A5 mutation on neuropathy grade and assist of ADL as a part of neurotoxicity.PMID:38680001 | DOI:10.31557/APJCP.2024.25.4.1391 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Norhan Shalaby Hala F Zaki Osama A Badary Sherif Kamal Mohamed Nagy Dalia Makhlouf Amr Elnashar Enas Elnadi Sameh A Abdelshafi Sherif Abouelnaga Mona M Saber Source Type: research
PD-L1 Immunohistochemical Expression in Endometrial Carcinoma: Egyptian Cross-Sectional Study
CONCLUSION: Our results concluded that PD-L1 expression was greater in both TCs and TILs in a subgroup of patients that have advanced age, LVSI and are TILs-rich, identifying them as potential candidates for anti-PD-1/PD-L1 immunotherapy.PMID:38680006 | DOI:10.31557/APJCP.2024.25.4.1441 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Maha Gamal Wahba Soliman Saba Soliman Maha Elsayed Salama Sarah Nasr Zeinab Abd El-Azeem Al Shereef Source Type: research
Evaluation of Circular RNA SMARCA5 as a Novel Biomarker for Hepatocellular Carcinoma
CONCLUSION: CircSMARCA5 has the potential to be a more sensitive predictor of HCC disease compared to AFP.PMID:38680002 | DOI:10.31557/APJCP.2024.25.4.1411 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Hanan M Bedair Elaf A El-Banna Elhamy A Ahmed Mostafa G Elhelbawy Ahmed Abdelfattah Fatma A Khalaf Mohamed Abdel-Samiee Amal El Sharnoby Source Type: research
Efficacy and Toxicity of Vincristine and CYP3A5 Genetic Polymorphism in Rhabdomyosarcoma Pediatric Egyptian Patients
CONCLUSION: CYP3A5*1/*1 have less severe vincristine-induced neuropathy than CYP3A5 *1/*3, CYP3A5 *1/*6 and CYP3A5 *3/*3, CYP3A5 *3/*6. There is a significant influence of CYP3A5 mutation on neuropathy grade and assist of ADL as a part of neurotoxicity.PMID:38680001 | DOI:10.31557/APJCP.2024.25.4.1391 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Norhan Shalaby Hala F Zaki Osama A Badary Sherif Kamal Mohamed Nagy Dalia Makhlouf Amr Elnashar Enas Elnadi Sameh A Abdelshafi Sherif Abouelnaga Mona M Saber Source Type: research
PD-L1 Immunohistochemical Expression in Endometrial Carcinoma: Egyptian Cross-Sectional Study
CONCLUSION: Our results concluded that PD-L1 expression was greater in both TCs and TILs in a subgroup of patients that have advanced age, LVSI and are TILs-rich, identifying them as potential candidates for anti-PD-1/PD-L1 immunotherapy.PMID:38680006 | DOI:10.31557/APJCP.2024.25.4.1441 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Maha Gamal Wahba Soliman Saba Soliman Maha Elsayed Salama Sarah Nasr Zeinab Abd El-Azeem Al Shereef Source Type: research
Evaluation of Circular RNA SMARCA5 as a Novel Biomarker for Hepatocellular Carcinoma
CONCLUSION: CircSMARCA5 has the potential to be a more sensitive predictor of HCC disease compared to AFP.PMID:38680002 | DOI:10.31557/APJCP.2024.25.4.1411 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Hanan M Bedair Elaf A El-Banna Elhamy A Ahmed Mostafa G Elhelbawy Ahmed Abdelfattah Fatma A Khalaf Mohamed Abdel-Samiee Amal El Sharnoby Source Type: research
Efficacy and Toxicity of Vincristine and CYP3A5 Genetic Polymorphism in Rhabdomyosarcoma Pediatric Egyptian Patients
CONCLUSION: CYP3A5*1/*1 have less severe vincristine-induced neuropathy than CYP3A5 *1/*3, CYP3A5 *1/*6 and CYP3A5 *3/*3, CYP3A5 *3/*6. There is a significant influence of CYP3A5 mutation on neuropathy grade and assist of ADL as a part of neurotoxicity.PMID:38680001 | DOI:10.31557/APJCP.2024.25.4.1391 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Norhan Shalaby Hala F Zaki Osama A Badary Sherif Kamal Mohamed Nagy Dalia Makhlouf Amr Elnashar Enas Elnadi Sameh A Abdelshafi Sherif Abouelnaga Mona M Saber Source Type: research
PD-L1 Immunohistochemical Expression in Endometrial Carcinoma: Egyptian Cross-Sectional Study
CONCLUSION: Our results concluded that PD-L1 expression was greater in both TCs and TILs in a subgroup of patients that have advanced age, LVSI and are TILs-rich, identifying them as potential candidates for anti-PD-1/PD-L1 immunotherapy.PMID:38680006 | DOI:10.31557/APJCP.2024.25.4.1441 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Maha Gamal Wahba Soliman Saba Soliman Maha Elsayed Salama Sarah Nasr Zeinab Abd El-Azeem Al Shereef Source Type: research
Evaluation of Circular RNA SMARCA5 as a Novel Biomarker for Hepatocellular Carcinoma
CONCLUSION: CircSMARCA5 has the potential to be a more sensitive predictor of HCC disease compared to AFP.PMID:38680002 | DOI:10.31557/APJCP.2024.25.4.1411 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Hanan M Bedair Elaf A El-Banna Elhamy A Ahmed Mostafa G Elhelbawy Ahmed Abdelfattah Fatma A Khalaf Mohamed Abdel-Samiee Amal El Sharnoby Source Type: research
Efficacy and Toxicity of Vincristine and CYP3A5 Genetic Polymorphism in Rhabdomyosarcoma Pediatric Egyptian Patients
CONCLUSION: CYP3A5*1/*1 have less severe vincristine-induced neuropathy than CYP3A5 *1/*3, CYP3A5 *1/*6 and CYP3A5 *3/*3, CYP3A5 *3/*6. There is a significant influence of CYP3A5 mutation on neuropathy grade and assist of ADL as a part of neurotoxicity.PMID:38680001 | DOI:10.31557/APJCP.2024.25.4.1391 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - April 29, 2024 Category: Cancer & Oncology Authors: Norhan Shalaby Hala F Zaki Osama A Badary Sherif Kamal Mohamed Nagy Dalia Makhlouf Amr Elnashar Enas Elnadi Sameh A Abdelshafi Sherif Abouelnaga Mona M Saber Source Type: research
Association between arachidonate lipoxygenase 15,c.-292 C & gt; T gene polymorphism and non-cystic fibrosis bronchiectasis in children: a pilot study on the effects on airway lipoxin A4 and disease phenotype
ConclusionsLow airway LXA4 in children with NCFB is associated with severe disease phenotype and lung function deterioration.CTgenotype ofALOX-15,c.-292 C> Tpolymorphism might be a protective genetic factor against bronchiectasis development and/or progression due to enhanced LXA4 production. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - April 29, 2024 Category: Pediatrics Source Type: research
Prognostic Value of Hyperglycemia and Insulin Resistance Among Patients with Confirmed COVID-19 Infections at Admission to the Alexandria Fever Hospital, Egypt
Metabolic Syndrome and Related Disorders, Ahead of Print. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - April 29, 2024 Category: Endocrinology Authors: Fathy Z. Alsewy Magdy H. Megallaa Salma A. Imbaby Huda M. Zidan Heba S. Kassab Mai H. Badrah Source Type: research
miR-939, as an important regulator in various cancers pathogenesis, has diagnostic, prognostic, and therapeutic values: a review
CONCLUSION: Our study highlights the potential of miR-939 as a valuable target in cancer diagnosis, prognosis, and treatment. The aberrant expression of miR-939, along with other miRNAs, underscores their significance in advancing our understanding of cancer biology and their promise in personalized cancer care.PMID:38679648 | DOI:10.1186/s43046-024-00220-8 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 28, 2024 Category: Cancer & Oncology Authors: Hosein Kouchaki Parnia Kamyab Farzaneh Darbeheshti Arezou Gharezade Hamed Fouladseresht Reza Tabrizi Source Type: research
miR-939, as an important regulator in various cancers pathogenesis, has diagnostic, prognostic, and therapeutic values: a review
CONCLUSION: Our study highlights the potential of miR-939 as a valuable target in cancer diagnosis, prognosis, and treatment. The aberrant expression of miR-939, along with other miRNAs, underscores their significance in advancing our understanding of cancer biology and their promise in personalized cancer care.PMID:38679648 | DOI:10.1186/s43046-024-00220-8 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 28, 2024 Category: Cancer & Oncology Authors: Hosein Kouchaki Parnia Kamyab Farzaneh Darbeheshti Arezou Gharezade Hamed Fouladseresht Reza Tabrizi Source Type: research
miR-939, as an important regulator in various cancers pathogenesis, has diagnostic, prognostic, and therapeutic values: a review
CONCLUSION: Our study highlights the potential of miR-939 as a valuable target in cancer diagnosis, prognosis, and treatment. The aberrant expression of miR-939, along with other miRNAs, underscores their significance in advancing our understanding of cancer biology and their promise in personalized cancer care.PMID:38679648 | DOI:10.1186/s43046-024-00220-8 (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - April 28, 2024 Category: Cancer & Oncology Authors: Hosein Kouchaki Parnia Kamyab Farzaneh Darbeheshti Arezou Gharezade Hamed Fouladseresht Reza Tabrizi Source Type: research
