The A2 haplotype of Echinococcus multilocularis is the predominant variant infecting humans and dogs in Yili Prefecture, Xinjiang
In this study, 127 samples were used for haplotypes analysis, including 79 tissues from humans, 43 liver tissues from small rodents, and 5 fecal samples from dogs. Genetic variability in E. multilocularis was studied using complete sequences of the mitochondrial (mt) genes of cytochrome b (cob), NADH dehydrogenase subunit 2 (nad2), and cytochrome c oxidase subunit 1 (cox1), using a total of 3558 bp per sample. The Asia haplotype 2 (A2) was the dominant haplotype, with 72.15% (57/79) prevalence in humans, 2.33% (1/43) in small rodents, and 80.00% (4/5) in dogs, followed by A5, the second most common haplotype, which infecte...
Source: Infection, Genetics and Evolution - March 3, 2024 Category: Genetics & Stem Cells Authors: Baoping Guo None Cairen Jianyong Wu Wenli Wang Bingjie Wang Yuan Ren Mayire Aizezi Rongsheng Mi Li Zhao Hao Wen Source Type: research
Effects of annexin B18 from Echinococcus granulosus sensu lato on mouse macrophages
Exp Parasitol. 2024 Mar 1:108723. doi: 10.1016/j.exppara.2024.108723. Online ahead of print.ABSTRACTCystic echinococcosis (CE) is a zoonotic disease, caused by Echinococcus granulosus sensu lato (E. granulosus s. l.), which posed significant public health concern globally. E. granulosus s. l. annexin B18 (EgANXB18) acts as a secretory protein, exerting a crucial influence in mediating host-parasite interactions. Recombinant annexin B18 (rEgANXB18) was expressed by Escherichia coli and the immunoreactivity was assessed by western blotting. The binding affinity between rEgANXB18 and total protein of RAW264.7 cells was assess...
Source: Experimental Parasitology - March 3, 2024 Category: Parasitology Authors: Yanxin Chen Ruiqi Hua Guoqing Shao Xiaowei Zhu Wei Hou Shengqiong Li Aiguo Yang Guangyou Yang Source Type: research
The A2 haplotype of Echinococcus multilocularis is the predominant variant infecting humans and dogs in Yili Prefecture, Xinjiang
In this study, 127 samples were used for haplotypes analysis, including 79 tissues from humans, 43 liver tissues from small rodents, and 5 fecal samples from dogs. Genetic variability in E. multilocularis was studied using complete sequences of the mitochondrial (mt) genes of cytochrome b (cob), NADH dehydrogenase subunit 2 (nad2), and cytochrome c oxidase subunit 1 (cox1), using a total of 3558 bp per sample. The Asia haplotype 2 (A2) was the dominant haplotype, with 72.15% (57/79) prevalence in humans, 2.33% (1/43) in small rodents, and 80.00% (4/5) in dogs, followed by A5, the second most common haplotype, which infecte...
Source: Infection, Genetics and Evolution - March 3, 2024 Category: Genetics & Stem Cells Authors: Baoping Guo None Cairen Jianyong Wu Wenli Wang Bingjie Wang Yuan Ren Mayire Aizezi Rongsheng Mi Li Zhao Hao Wen Source Type: research
Effects of annexin B18 from Echinococcus granulosus sensu lato on mouse macrophages
Exp Parasitol. 2024 Mar 1:108723. doi: 10.1016/j.exppara.2024.108723. Online ahead of print.ABSTRACTCystic echinococcosis (CE) is a zoonotic disease, caused by Echinococcus granulosus sensu lato (E. granulosus s. l.), which posed significant public health concern globally. E. granulosus s. l. annexin B18 (EgANXB18) acts as a secretory protein, exerting a crucial influence in mediating host-parasite interactions. Recombinant annexin B18 (rEgANXB18) was expressed by Escherichia coli and the immunoreactivity was assessed by western blotting. The binding affinity between rEgANXB18 and total protein of RAW264.7 cells was assess...
Source: Experimental Parasitology - March 3, 2024 Category: Parasitology Authors: Yanxin Chen Ruiqi Hua Guoqing Shao Xiaowei Zhu Wei Hou Shengqiong Li Aiguo Yang Guangyou Yang Source Type: research
The A2 haplotype of Echinococcus multilocularis is the predominant variant infecting humans and dogs in Yili Prefecture, Xinjiang
In this study, 127 samples were used for haplotypes analysis, including 79 tissues from humans, 43 liver tissues from small rodents, and 5 fecal samples from dogs. Genetic variability in E. multilocularis was studied using complete sequences of the mitochondrial (mt) genes of cytochrome b (cob), NADH dehydrogenase subunit 2 (nad2), and cytochrome c oxidase subunit 1 (cox1), using a total of 3558 bp per sample. The Asia haplotype 2 (A2) was the dominant haplotype, with 72.15% (57/79) prevalence in humans, 2.33% (1/43) in small rodents, and 80.00% (4/5) in dogs, followed by A5, the second most common haplotype, which infecte...
Source: Infection, Genetics and Evolution - March 3, 2024 Category: Genetics & Stem Cells Authors: Baoping Guo None Cairen Jianyong Wu Wenli Wang Bingjie Wang Yuan Ren Mayire Aizezi Rongsheng Mi Li Zhao Hao Wen Source Type: research
Effects of annexin B18 from Echinococcus granulosus sensu lato on mouse macrophages
Exp Parasitol. 2024 Mar 1:108723. doi: 10.1016/j.exppara.2024.108723. Online ahead of print.ABSTRACTCystic echinococcosis (CE) is a zoonotic disease, caused by Echinococcus granulosus sensu lato (E. granulosus s. l.), which posed significant public health concern globally. E. granulosus s. l. annexin B18 (EgANXB18) acts as a secretory protein, exerting a crucial influence in mediating host-parasite interactions. Recombinant annexin B18 (rEgANXB18) was expressed by Escherichia coli and the immunoreactivity was assessed by western blotting. The binding affinity between rEgANXB18 and total protein of RAW264.7 cells was assess...
Source: Experimental Parasitology - March 3, 2024 Category: Parasitology Authors: Yanxin Chen Ruiqi Hua Guoqing Shao Xiaowei Zhu Wei Hou Shengqiong Li Aiguo Yang Guangyou Yang Source Type: research
The A2 haplotype of Echinococcus multilocularis is the predominant variant infecting humans and dogs in Yili Prefecture, Xinjiang
In this study, 127 samples were used for haplotypes analysis, including 79 tissues from humans, 43 liver tissues from small rodents, and 5 fecal samples from dogs. Genetic variability in E. multilocularis was studied using complete sequences of the mitochondrial (mt) genes of cytochrome b (cob), NADH dehydrogenase subunit 2 (nad2), and cytochrome c oxidase subunit 1 (cox1), using a total of 3558 bp per sample. The Asia haplotype 2 (A2) was the dominant haplotype, with 72.15% (57/79) prevalence in humans, 2.33% (1/43) in small rodents, and 80.00% (4/5) in dogs, followed by A5, the second most common haplotype, which infecte...
Source: Infection, Genetics and Evolution - March 3, 2024 Category: Genetics & Stem Cells Authors: Baoping Guo None Cairen Jianyong Wu Wenli Wang Bingjie Wang Yuan Ren Mayire Aizezi Rongsheng Mi Li Zhao Hao Wen Source Type: research
The A2 haplotype of Echinococcus multilocularis is the predominant variant infecting humans and dogs in Yili Prefecture, Xinjiang
In this study, 127 samples were used for haplotypes analysis, including 79 tissues from humans, 43 liver tissues from small rodents, and 5 fecal samples from dogs. Genetic variability in E. multilocularis was studied using complete sequences of the mitochondrial (mt) genes of cytochrome b (cob), NADH dehydrogenase subunit 2 (nad2), and cytochrome c oxidase subunit 1 (cox1), using a total of 3558 bp per sample. The Asia haplotype 2 (A2) was the dominant haplotype, with 72.15% (57/79) prevalence in humans, 2.33% (1/43) in small rodents, and 80.00% (4/5) in dogs, followed by A5, the second most common haplotype, which infecte...
Source: Infection, Genetics and Evolution - March 3, 2024 Category: Genetics & Stem Cells Authors: Baoping Guo None Cairen Jianyong Wu Wenli Wang Bingjie Wang Yuan Ren Mayire Aizezi Rongsheng Mi Li Zhao Hao Wen Source Type: research
Biomedical behaviors of CuO/ γ-alumina/chitosan nanocomposites: Scolicidal and apoptotic effects on hydatid cysts protoscolices
In conclusion, this study suggests that the phytosynthesized CuO/γ-Al2O3 NC and the CuO NPs could be potential candidates for treating echinococcosis by killing the PSCs through apoptosis. Further studies are needed to verify the in vivo efficacy and toxicity of these NMs and to optimize their delivery and targeting systems.PMID:38423424 | DOI:10.1016/j.ijbiomac.2024.130515 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - February 29, 2024 Category: Biochemistry Authors: Azra Bagherivand Saeed Jafarirad Roghayeh Norouzi Abbas Karimi Source Type: research
Assessment of oxidative stress and tissue damage in Echinococcus granulosus naturally infected bovine liver
This study highlights the role of oxidative stress in the pathogenesis of Cystic Echinococcosis (CE) and the need for further investigation of antioxidant defense mechanisms and their regional variations.PMID:38422584 | DOI:10.1016/j.tice.2024.102333 (Source: Tissue and Cell)
Source: Tissue and Cell - February 29, 2024 Category: Cytology Authors: Tu ğçe Antepli Oğlu Tilbe Su Yapici Gungor Cagdas Dincel Ebtesam Al-Olayan Mohammad Y Alshahrani Saeed El-Ashram Source Type: research
Assessment of oxidative stress and tissue damage in Echinococcus granulosus naturally infected bovine liver
This study highlights the role of oxidative stress in the pathogenesis of Cystic Echinococcosis (CE) and the need for further investigation of antioxidant defense mechanisms and their regional variations.PMID:38422584 | DOI:10.1016/j.tice.2024.102333 (Source: Tissue and Cell)
Source: Tissue and Cell - February 29, 2024 Category: Cytology Authors: Tu ğçe Antepli Oğlu Tilbe Su Yapici Gungor Cagdas Dincel Ebtesam Al-Olayan Mohammad Y Alshahrani Saeed El-Ashram Source Type: research
Comparison of the Diagnostic Performance of Antigen B Purified from Sheep Hydatid Cyst Fluid (HCF) with Commercial ELISA Kit
CONCLUSION: Antigen B produced from hydatid cyst fluid is a promising option for serological identification of hydatid cysts in both infected and healthy individuals. In an indirect ELISA test, hydatid fluid antigen could be used as a precise source of detection.PMID:38415436 | DOI:10.2174/0118715265281114240131045945 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 28, 2024 Category: Infectious Diseases Authors: Fatemeh Abdollahpour Darzi Hossein Asgarian-Omran Shahabeddin Sarvi Reza Valadan Maryam Hataminejad Sabah Mayahi Seyyed Ali Shariatzadeh Takatom Abbasi Tahereh Mikaeili Galeh Mahdi Fakhar Majid Fassihi Harandi Shirzad Gholami Source Type: research
Diagnosis and treatment experience of atypical hepatic cystic echinococcosis type 1 at a tertiary center in China
CONCLUSION: Abdominal high-frequency ultrasound can detect CE1 hydatid cysts. The laparoscopic technique serves as a more effective diagnostic and therapeutic tool for CE.PMID:38414590 | PMC:PMC10895592 | DOI:10.3748/wjg.v30.i5.462 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - February 28, 2024 Category: Gastroenterology Authors: Yu-Peng Li Jie Zhang Zhi-De Li Chao Ma Guang-Lei Tian Yuan Meng Xiong Chen Zhi-Gang Ma Source Type: research
Diagnosis and treatment experience of atypical hepatic cystic echinococcosis type 1 at a tertiary center in China
CONCLUSION: Abdominal high-frequency ultrasound can detect CE1 hydatid cysts. The laparoscopic technique serves as a more effective diagnostic and therapeutic tool for CE.PMID:38414590 | PMC:PMC10895592 | DOI:10.3748/wjg.v30.i5.462 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - February 28, 2024 Category: Gastroenterology Authors: Yu-Peng Li Jie Zhang Zhi-De Li Chao Ma Guang-Lei Tian Yuan Meng Xiong Chen Zhi-Gang Ma Source Type: research
Comparison of the Diagnostic Performance of Antigen B Purified from Sheep Hydatid Cyst Fluid (HCF) with Commercial ELISA Kit
CONCLUSION: Antigen B produced from hydatid cyst fluid is a promising option for serological identification of hydatid cysts in both infected and healthy individuals. In an indirect ELISA test, hydatid fluid antigen could be used as a precise source of detection.PMID:38415436 | DOI:10.2174/0118715265281114240131045945 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - February 28, 2024 Category: Infectious Diseases Authors: Fatemeh Abdollahpour Darzi Hossein Asgarian-Omran Shahabeddin Sarvi Reza Valadan Maryam Hataminejad Sabah Mayahi Seyyed Ali Shariatzadeh Takatom Abbasi Tahereh Mikaeili Galeh Mahdi Fakhar Majid Fassihi Harandi Shirzad Gholami Source Type: research
