Answer to Case 675
Answer to theParasite Case of the Week 675: Coenurosis, a tapeworm infection with the larval form of coenurus-forming Taeniaspecies, such asT. multiceps(the most commonly implicated species), T. serialis, T. brauni,andT. glomeratus. Some of you noted the resemblance of this tissue infection with cysticercosis. That makes sense since human cysticercosis is due to the related cestode,Taenia solium.The primary difference is the presence of a single protoscolex in cysticercosis, vs. multiple protoscoleces in coenurosis.Here is my approach to the diagnosis:We can first tell this is a cestode by the presence of the cal...
Source: Creepy Dreadful Wonderful Parasites - March 5, 2022 Category: Parasitology Source Type: blogs

Answer to Case 614
 Answer to Parasite Case of the Week 614: Cystic echinococcosis caused by a member of the Echincoccusgranulosuscomplex. As Clinton White nicely explained in thecase comments, " We now know that human infection is caused by several species and genotypes within what was once thought of as a single species. " The species implicated in human disease areE. granulosus(genotypes G1-G3),E. ortleppi(G5), and E. canadensis(G6-G8, G10). Most of these have a wide geographic distribution, including regions of North America, Europe, Asia, and the Middle East. In South America, 2 additional species cause neotropi...
Source: Creepy Dreadful Wonderful Parasites - November 8, 2020 Category: Parasitology Source Type: blogs

Answer to Case 514
Answer: Hydatid sand of Echinococcussp.; mostly likelyEchinococcus granulosusdue to the abundant protoscoleces/hooklets and presence within a single cyst. The photo from this case shows numerous free hooklets in the background of degenerating protoscoloces. As Blaine pointed out, the mixture of disintegrating protoscoleces with free hooklets and calcareous corpuscles is often referred to as " hydatid sand. "As Old One pointed out, the protoscoleces have a rostellum with 2 rows of hooklets - one row of large hooklets and one row of small hooklets - making this cestode " armed " . He further notes that having an ar...
Source: Creepy Dreadful Wonderful Parasites - October 7, 2018 Category: Parasitology Source Type: blogs

Real Lessons From the Liver Queen
By MARTIN SAMUELS, MD In 1970 I had the opportunity to spend time at the Royal Free Hospital in London.  One of my professors at The University of Cincinnati College of Medicine, the late Leon Schiff, a renowned liver expert, arranged for me to work under Professor Sheila Sherlock.  I was placed in a laboratory that was investigating the presumed immune basis of primary biliary cirrhosis.  Roy Fox and Frank Dudley, the faculty in the lab, warmly welcomed me and taught me the basics of immunology research.  My first scientific paper in Gut, was based on this work.  But, I was a budding clinician and I was drawn to the ...
Source: The Health Care Blog - June 24, 2015 Category: Consumer Health News Authors: John Irvine Tags: THCB Source Type: blogs

Real Mentoring Lessons From the Liver Queen
By MARTIN SAMUELS, MD In 1970 I had the opportunity to spend time at the Royal Free Hospital in London.  One of my professors at The University of Cincinnati College of Medicine, the late Leon Schiff, a renowned liver expert, arranged for me to work under Professor Sheila Sherlock.  I was placed in a laboratory that was investigating the presumed immune basis of primary biliary cirrhosis.  Roy Fox and Frank Dudley, the faculty in the lab, warmly welcomed me and taught me the basics of immunology research.  My first scientific paper in Gut, was based on this work.  But, I was a budding clinician and I was drawn to the ...
Source: The Health Care Blog - June 24, 2015 Category: Consumer Health News Authors: John Irvine Tags: THCB Source Type: blogs

Answer to Case 280
Answer :  Echinococcus sp. protoscolecesThank you all for writing in.  I agree that this is, statistically speaking, Echinococcus granulosus infection, although from just the microbiology findings, I would report this out as Echinococcus species, given that E. multilocularis and other Echinococcus species could have a similar presentation early on.The key to diagnosis of echinococcosis is identification of the characteristic protoscoleces with internalized hooklets. In the canine host, the hooklets will evert and attach to the intestinal epithelium, with subsequent development into an adult worm. And now our fun ...
Source: Creepy Dreadful Wonderful Parasites - November 4, 2013 Category: Pathologists Source Type: blogs