Empowering Trainees to be Leaders and Change Agents
We described several wellness initiatives that were done at individual campuses. The University of Illinois where I attend, we had a wellness committee that we formed led by students. We were able to partner with local companies to bring in more healthy food options. We were able to set up a counseling center dedicated specifically towards medical trainees.
Joe Geraghty:
And so that’s at the institutional level, but then in our local community, we had several letters from places like the University of Chicago. We had a medical student who wrote about how they were developing kind of like easy to digest infograp...
Source: Academic Medicine Blog - April 25, 2022 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Annual Call for Trainee-Authored Letters to the Editor ATLAS Trainee Perspective leadership medical education scholarship medical students residents scholarly publishing trainee engagement Source Type: blogs
An Outline of Present Work on Partial Reprogramming as a Rejuvenation Therapy
Here I'll point out a good, lengthy introduction to the ongoing, suddenly very well funded work on partial reprogramming as the basis for rejuvenation therapies. Reprogramming somatic cells to induced pluripotent stem cells requires exposure to the Yamanaka factors, but is a lengthy process with low efficiency. Early in that process, epigenetic patterns in a cell are restored to a more youthful configuration without the loss of differentiated somatic cell state, and this is the goal that partial reprogramming aims to achieve: restore mitochondrial function and many other cell activities in old tissues without changing cell...
Source: Fight Aging! - April 25, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, April 18th 2022
In conclusion, our results suggest that SAH extends lifespan by inducing MetR or mimicking its downstream effects. Since the lifespan-extending effects of SAH are conserved in yeast and nematodes, and MetR extends the lifespan of many species, exposure to SAH is expected to have multiple benefits across evolutionary boundaries. Our findings offer the enticing possibility that in humans the benefits of a MetR diet can be achieved by promoting Met reduction with SAH. The use of endogenous metabolites, such as SAH, is considered safer than drugs and other substances, suggesting that it may be one of the most feasible ways to ...
Source: Fight Aging! - April 17, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Printed Fingertip with Enhanced Tactile Sense
Researchers at the University of Bristol in the UK have created a 3D printed fingertip that is designed for use by robots or as a component of robotic prostheses. The structure mimics the dermal papillae found in human skin, which are small bumps present between the dermis and epidermis that are important in human touch. In the printed fingertip, the papillae are created through a 3D printed mesh of pin-like structures that lie beneath a flexible “skin” coating, and their displacement and speed of movement inform the robot about the objects it is touching. So far, the artificial fingertips have been shown to mimic huma...
Source: Medgadget - April 15, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Materials Rehab Source Type: blogs
Towards Improved Partial Reprogramming Techniques as a Basis for Rejuvenation Therapies
Partial reprogramming involves exposing cells to the Yamanaka factors capable of turning somatic cells into induced pluripotent stem cells, but not for so long as to result in that transformation. The initial stage of reprogramming, prior to transformation into stem cells, in which epigenetic marks are reset to a youthful configuration, is the desirable outcome. This results in rejuvenation of cell function, as protein production and the operation of cellular processes return to that of youth. This cannot repair DNA damage, and will probably help little with problems relating to persistent metabolic waste in long-lived cel...
Source: Fight Aging! - April 14, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
From Surgeries To Keeping Company: The Place Of Robots In Healthcare
Assisting surgeries, disinfecting rooms, dispensing medication, keeping company: believe it or not these are the tasks medical robots will soon undertake in hospitals, pharmacies, or your nearest doctor’s office. These new ‘colleagues’ will definitely make a difference in every field of medicine. Here’s our overview to understand robotics in healthcare better so that everyone can prepare for the appearance of mechanic helpers in medical facilities.
Metallic allies for the benefit of the vulnerable
While there are concerns for machines replacing people in the workforce, we believe there are adv...
Source: The Medical Futurist - April 11, 2022 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Future of Pharma Robotics digital health Healthcare Hospital medical nanotechnology Surgery pharmacies future of hospital blood telemedicine social companion social companion robot telemedical medical rob Source Type: blogs
Fight Aging! Newsletter, February 21st 2022
In conclusion, clinical trials targeting aging in humans have shown promising but limited results on biomarkers so far.
Mycobacterium Vaccae Immunization as an Anti-Inflammatory Strategy
https://www.fightaging.org/archives/2022/02/mycobacterium-vaccae-immunization-as-an-anti-inflammatory-strategy/
In today's open access paper, researchers discuss immunization with Mycobacterium vaccae as an approach to reduce the inflammatory overactivity of the aged immune system. Researchers have made some initial inroads into studying the way in which this bacteria can alter the function of the immune system, and her...
Source: Fight Aging! - February 20, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Discussing the Present State of Clinical Trials for Therapies that Target Mechanisms of Aging
In conclusion, clinical trials targeting aging in humans have shown promising but limited results on biomarkers so far. (Source: Fight Aging!)
Source: Fight Aging! - February 15, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, February 14th 2022
In conclusion, this first examination of the effects of age and the ageing process on the small intestinal microbiome demonstrates that the duodenal microbiome changes with increasing age, with significant decreases in duodenal microbial diversity due to increased prevalence of phylum Proteobacteria, particularly coliforms and anaerobic taxa. Given the key roles of small intestinal microbes in nutrient absorption and host metabolism, these changes may be clinically relevant for human health during the ageing process.
Naked Mole Rats Exhibit Minimal Cardiac Aging
https://www.fightaging.org/archives/2022/02/nake...
Source: Fight Aging! - February 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
BREAKING: Thirty Madison and Nurx Merge, CEO Steve Gutentag Takes Us Inside
By JESSICA DaMASSA, WTF HEALTH
Thirty Madison and Nurx are merging and here’s what Steve Gutentag, CEO of Thirty Madison and the soon-to-be-combined entity, is saying about the deal!
This is a merger of two well-funded, direct-to-consumer, virtual-care-plus-pharmacy startups that deliver specialty and expert care and prescription drugs to a combined 750,000 active patients, with or without insurance. To-date, Nurx has raised a total $110 million, and Thirty Madison closed a Series C in June 2021 that brought their total funding to $210 million with a then-valuation of over $1 billion.
Thirty Madison currently ...
Source: The Health Care Blog - February 9, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech WTF Health Jessica DaMassa mental health care Nurx Steve Gutentag thirty madison virtual care Source Type: blogs
25-Hydroxycholesterol as a Basis for Senolytic Therapy
25-hydroxycholesterol is an oxidized form of cholesterol, and researchers here demonstrate that it is senolytic to some degree in mice. This may be competitive with existing first generation senolytics; from the paper, it looks like it clears about half of the excess of senescent cells present in old mice, in muscle tissue at least. Like all other senolytics, its effectiveness likely varies widely by tissue type and location in the body. Oxidized cholesterols are largely thought to be harmful in the body, particularly because they can cause macrophages to become dysfunctional and accelerate the progression of atheroscleros...
Source: Fight Aging! - February 9, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, January 17th 2022
In conclusion, fibroblasts in monolayers cultured with soluble pentosidine and tridimensional in vitro skin constructs exposed to the combination of AGEs and UVA promote an inflammatory state and an alteration of the dermal compartment in relation to an elastosis-like environment. (Source: Fight Aging!)
Source: Fight Aging! - January 16, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
UV Radiation and Cross-Linking Contribute to Elastosis in Aged Skin
In conclusion, fibroblasts in monolayers cultured with soluble pentosidine and tridimensional in vitro skin constructs exposed to the combination of AGEs and UVA promote an inflammatory state and an alteration of the dermal compartment in relation to an elastosis-like environment.
Link: https://doi.org/10.1155/2021/6647773 (Source: Fight Aging!)
Source: Fight Aging! - January 14, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Top 5 Medical Innovations To Look Out For In 2022
As they say, new year, new beginnings; and this also applies to the field of digital health! With the COVID-19 pandemic still raging, the crisis has led to the adoption of certain trends in response to the challenges it raised. In general, this tends to bring the point of care to wherever the patient is. As more investment and research focus are diverted towards those relevant fields, this will help generate more innovations from those areas.
Even if they might not become the point of focus in 2022, these “predictions” usually follow through with time. For instance, for 2020 we forecasted a new line of Googl...
Source: The Medical Futurist - January 4, 2022 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Covid-19 Artificial Intelligence in Medicine Digital Health Research Future of Medicine Health Insurance Healthcare Design Telemedicine & Smartphones google microbiome genome sequencing A.I. vocal biomarkers at-home tests deepmin Source Type: blogs
Arizona Republic Report Leaves Out Important Details and Context On Universal Licensing
Jeffrey A. SingerThe Arizona Republic recently published a report entitled, “Universal Licensing: Arizona opened the doors to less qualified workers ‐the public bears the risk. ” In its investigation of Arizona’suniversal licensing recognition law enacted in 2019 —a reform so successful and popular that it is being emulated by more than a third of other states—it mentioned irrelevant incidents and presented out‐of‐context data to malign this bold and enlightened reform.The article begins and ends with a heart‐wrenching story about a California‐licensed veterinarian who received a t...
Source: Cato-at-liberty - January 3, 2022 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs
