Answer to Case 695
The following excellent answer to this week ' s case is by our guest author, Jacob Rattin (@eternalstudying), medical student and future pathologist. Answer to theParasite Case of the Week 695:Strongyloides stercoralishyperinfection. Many readers commented that this wasStrongyloides stercoralis, with several Twitter and LinkedIn users correctly mentioning “hyperinfection.” Great job! Here is the DIGITAL SLIDE for your reference. While this case had a very sad outcome, it highlights important features ofStrongyloides hyperinfection. Individuals who are elderly or immunocompromised (eg, soli...
Source: Creepy Dreadful Wonderful Parasites - September 18, 2022 Category: Parasitology Source Type: blogs

Weekly Overseas Health IT Links –10th September, 2022.
This article is adapted fromVoices in the Code: A Story About People, Their Values, and the Algorithm They Made,out Sept. 8 from Russell Sage Foundation Press.In May 2021, I got a call I never expected. I was working on abook about A.I. ethics, focused on the algorithm that gives out kidneys to transplant patients in the United States. Darren Stewart —a data scientist from UNOS, the nonprofit that runs the kidney allocation process—was calling to get my take: How many decimal places should they include when calculating each patient’s allocation score? The score is an incredibly important number, given it determines w...
Source: Australian Health Information Technology - September 10, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

How An A.I.-Based Skin Checking App Can Work With A National Healthcare System
You might be already familiar with skin checking apps, we too have discussed them quite extensively recently. Skin checking applications allow users to take pictures of their suspicious skin lesions, upload these pictures to a server, the images are first evaluated by an A.I. algorithm and the results will be later validated by a dermatologist.  However, this time there is something new under the sun: AIP Labs and Semmelweis University (Hungary’s leading medical university) developed a skin checking application that offers several features we have not seen before. It was launched to work integrated with the natio...
Source: The Medical Futurist - September 8, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine Digital Health Research E-Patients Future of Medicine Healthcare Design Healthcare Policy Telemedicine & Smartphones AI dermatology skin skin cancer skin checker skin checking app digital Source Type: blogs

Top 10 Research Topics To Pursue In Digital Health
The question we most frequently get at The Medical Futurist Institute is easily the one asking for guidance on potential research topics. In fact, we face it so often that we decided to write a summary of our thoughts to provide an overview and some insights to anyone who is willing to dive deep into digital health but is unsure about the best direction to take. Whatever you choose, take a look at these four criteria first Find a nicheAim for uncharted territoriesLook for ease of entrySeek answers to important questions We compiled a list of ten research topics we believe are in line with the above principles and ...
Source: The Medical Futurist - September 1, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Forecast Artificial Intelligence in Medicine Digital Health Research E-Patients Future of Medicine Health Sensors & Trackers Healthcare Design Healthcare Policy Portable Medical Diagnostics Telemedicine & Smartphones AI EMR v Source Type: blogs

How Will A.I. Penetrate Healthcare? Through Your Skin, Voice And Cough!
There is certainly no shortage of research on artificial intelligence, machine and deep learning algorithms these days. You will come across a number of announcements every week reporting on fascinating findings, new methods, and breakthrough results. Despite the unquestionable buzz, it is challenging to pinpoint examples that actually found their way into everyday medical practice, that became part of “standard” healthcare.  In this article, we will introduce three areas we believe will be the forerunners of the A.I. revolution in medicine and will discuss four principles that help to determine whether you ...
Source: The Medical Futurist - August 30, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Forecast Artificial Intelligence in Medicine Digital Health Research Future of Medicine AI doctors vocal biomarkers Future of healthcare medical algorithm skin checking app cough analysis Source Type: blogs

3 Powerful Real-World A.I. Examples That Are Used by Patients in Healthcare
There is certainly no shortage of research on artificial intelligence, machine and deep learning algorithms these days. You will come across a number of announcements every week reporting on fascinating findings, new methods, and breakthrough results. Despite the unquestionable buzz, it is challenging to pinpoint examples that actually found their way into everyday medical practice, that became part of “standard” healthcare.  In this article, we will introduce three areas we believe will be the forerunners of the A.I. revolution in medicine and will discuss four principles that help to determine whether you ...
Source: The Medical Futurist - August 30, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Forecast Artificial Intelligence in Medicine Digital Health Research Future of Medicine AI doctors vocal biomarkers Future of healthcare medical algorithm skin checking app cough analysis Source Type: blogs

Cardiac tumours
Cardiac tumours are most often secondaries from malignancies of breast, lung or malignant melanoma. Primary tumours of the heart are most often benign, of which about half are myxomas. Malignant primary tumours of the heart contribute to about a quarter of the primary cardiac tumours. The commonest primary malignant tumour of the heart would be a sarcoma [1]. Cardiac tumours may present with cardiovascular or constitutional symptoms. Sometimes they are incidentally detected on echocardiography or other imaging modalities. Left atrial myxoma on echocardiogram Computed tomography and magnetic resonance imaging can give addi...
Source: Cardiophile MD - August 25, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Tough Ultrasound-Controlled Bioadhesives
Scientists from McGill University in Canada created a technique of using ultrasound-mediated cavitation to make bioadhesives better stick to body’s tissues, including wet surfaces that are typically challenging for such materials. The new method involves ultrasound to create microbubbles within the adhesive. The bubbles burst, which then temporarily forces some of the adhesive components deeper into the underlying tissue, helping to create a stronger bond. The hydrogel adhesives are made using poly(N-isopropylacrylamide) or polyacrylamide combined with alginate, and also contain chitosan or gelatin nanopar...
Source: Medgadget - August 18, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Materials Plastic Surgery mcgilluniversitycanada Source Type: blogs

Amazing Technologies Changing The Future Of Dermatology
Smart algorithms will soon diagnose skin cancer, dermatologists consult patients online, and 3D printers will print out synthetic skin to fight tissue shortages. There is a lot going on in dermatology, and medical professionals should prepare in time for the technological changes before they start swiping through the specialty. Let’s start by familiarising ourselves with the most amazing technologies changing the future of dermatology! Skin cancer is too common According to statistics from the WHO, currently, some 1.5 million non-melanoma skin cancers and 325,000 melanoma skin cancers occur globally each year. Data...
Source: The Medical Futurist - August 4, 2022 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Telemedicine & Smartphones 3d printing AI artificial intelligence digital Healthcare Innovation nanotechnology Personalized medicine robotics wearables GC1 dermatology Source Type: blogs

Surgical Dressing Helps Kill Melanoma, Regenerate Healthy Cells
Scientists at the University of Nottingham in the UK have created a surgical dressing that is specifically designed to facilitate and enhance photothermal therapy following melanoma resection. The dressing allows for near-infrared photothermal therapy that lasts just 15 seconds every 48 hours. The concept involves killing any remaining melanoma cells, while encouraging healthy cells to regenerate within the resection site. The dressing contains graphene oxide (a photothermal agent, which converts the energy from light to heat, killing cancer cells), elastin, and ethanol. Combining the graphene oxide with elastin reduce...
Source: Medgadget - July 19, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Materials Medicine Oncology Rehab Surgery melanoma UniofNottingham Source Type: blogs

Fight Aging! Newsletter, July 4th 2022
This study showed that centenarians had very specific changes in CD4+ T cell populations, which were manifested by an elevated Th17/Treg ratio in vivo, as well as a changed secretory phenotype. Although the T cells of centenarians cannot resist the aging-related expression of proinflammatory genes, their secretory phenotype was altered, explaining the relatively low level of inflammation in centenarians. These results suggested the presence of a mechanism to ameliorate inflammaging in centenarians. This may be achieved by reversing the imbalance of Th17/Treg cells and reducing pro-inflammatory cytokines. Longevit...
Source: Fight Aging! - July 3, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

DDIT4 and HDAC4 Overexpression Reduces Harmful Signaling of Senescent Cells in Aged Tissues
Accumulation of senescent cells is an important aspect of degenerative aging. While never present in very large numbers, relative to the overall count of all cells in a tissue, senescent cells generate a potent mix of signals that induce inflammation and disrupt normal tissue maintenance and function. Clearance of senescent cells via senolytic therapies is the presently favored approach to this issue, but a sizable faction in the research community are instead interested in suppression of senescent cell signaling. Research into the detailed biochemistry of senescence may lead in either direction, both of which can give ris...
Source: Fight Aging! - June 28, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, June 27th 2022
In conclusion, this study confirms that innate immune training can be induced in aging healthy individuals as well as critically ill sepsis patients. We found that innate immune training can be induced regardless of age and there was no substantive difference in the immune trained phenotype as a function of age. We employed β-glucan as our immune training stimulus. The ability of glucan to induce the trained phenotype suggests that it may be possible to pharmacologically induce the immune trained phenotype in aging human immunocytes. Sitting Time Correlates with Mortality Risk https://www.fightaging.org/archi...
Source: Fight Aging! - June 26, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Want your skin to look better? Then consider your mental health. [PODCAST]
“Stigma surrounding mental illness often prevents patients from seeking the mental health care they need, delaying care and prolonging suffering. Fear, embarrassment, and impaired quality of life are a reality for many patients suffering from skin disorders like severe cases of psoriasis, hair loss, or acne. In these cases, assistance from a dermatologist who bridgesRead more …Want your skin to look better? Then consider your mental health. [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 25, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/the-podcast-by-kevinmd" rel="tag" data-wpel-link="internal" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Dermatology Psychiatry Source Type: blogs

The New Buzz: These Are The Top Examples Of Digital Therapeutics
Digital Therapeutics or DTx in short is one of the latest buzzwords in the digital health ecosystem. Unlike others (NFT, Metaverse just to name a few) however, we see DTx as a meaningful trend that has the capacity to bring short-term, substantial improvements in personalised healthcare.  What is Digital Therapeutics? The definition by the Digital Therapeutics Alliance, the main professional hub is:  “Digital therapeutics (DTx) deliver evidence-based therapeutic interventions that are driven by high-quality software programs to prevent, manage, or treat a medical disorder or disease. They are used inde...
Source: The Medical Futurist - June 21, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Digital Health Research Future of Medicine Health Sensors & Trackers Telemedicine & Smartphones software chronic pain apps cancer care mental health DTx digital therapeutics eczema Atopic dermatitis sleep disorders Source Type: blogs