Nanotransfection Device for Tissue Reprogramming In Situ
This report on how to exactly produce these tissue nanotransfection chips will enable other researchers to participate in this new development in regenerative medicine,” said Sen. The technology may be useful in delivering a wide variety of agents, including drugs and proteins, and so far, the researchers have proposed that it could administer agents to stimulate bone growth, blood vessel formation, nerve growth, muscle growth and even anti-tumor agents. Here’s a Indiana University video about the new technology: Study in Nature Protocols: Fabrication and use of silicon hollow-needle arrays to ac...
Source: Medgadget - December 16, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Genetics Materials Medicine Nanomedicine GoIU indianauniversity Source Type: blogs

Top 10 Healthcare Artificial Intelligence News Of 2021
As 2021 is about to wrap up, we are reflecting on some of the most important news revolving around artificial intelligence (A.I.) in healthcare. These range from the principles laying the groundwork for the safe and effective development of A.I.-powered medical devices to a sober look at the technology’s role in the pandemic. Without further ado, let’s take a look at the top 10 healthcare A.I. news of the year that was. 1. The FDA’s list of AI/ML-enabled medical devices marketed in the U.S. In September 2020, The Medical Futurist Institute (TMFI) had its first research published in the prestigious npj Digit...
Source: The Medical Futurist - December 14, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF Artificial Intelligence in Medicine Future of Medicine Healthcare Design Healthcare Policy fda google IBM ibm watson A.I. deepmind Alphabet Source Type: blogs

Fight Aging! Newsletter, December 13th 2021
In conclusion, there is a good amount of pre-clinical and clinical data showing a strong positive correlation between reduction of senescent cells frequencies and functional improvement of skin. Whether senescence of skin cells makes a significant causal contribution to skin ageing can still not be conclusively decided, however. Nonetheless, there is strong evidence existing today to assume that better understanding of cell senescence in skin may lead to a breakthrough in interventions into skin ageing. Isomerization of Tau May be Involved in Alzheimer's Disease https://www.fightaging.org/archives/2021/12/isom...
Source: Fight Aging! - December 12, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reviewing the Contribution of Cellular Senescence to Skin Aging
In conclusion, there is a good amount of pre-clinical and clinical data showing a strong positive correlation between reduction of senescent cells frequencies and functional improvement of skin. Whether senescence of skin cells makes a significant causal contribution to skin ageing can still not be conclusively decided, however. Nonetheless, there is strong evidence existing today to assume that better understanding of cell senescence in skin may lead to a breakthrough in interventions into skin ageing. (Source: Fight Aging!)
Source: Fight Aging! - December 10, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

December 2021: Check Out Checkpoint Inhibitors
​"Hey, can you check out this rash? It is all over," a nurse said to me."What can you tell me?""He has metastatic cancer. The rash started a couple days ago.""It's probably a checkpoint inhibitor rash. I'll check it out."Medicine has developed an entirely new approach to cancer since I went to medical school. Therapeutics were all about direct toxicity to rapidly dividing cells a few decades ago. Now we have an entirely new classification of treatment: immunotherapy.Immunotherapy tries to increase the body's ability to use its own defenses against cancer. One group of agents is...
Source: Lions and Tigers and Bears - December 1, 2021 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Think TikTok is smarter than me? Then I ’m not the right doctor for you.
“I don’t think I am the right doctor for you.” In over 20 years of practice, I had never uttered those words before this year. Now, as my medical assistant of 20 years remarks, almost two years into the pandemic, I say it almost daily. I like to think I am a good physician andRead more …Think TikTok is smarter than me? Then I’m not the right doctor for you. originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 27, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/bari-b-cunningham" rel="tag" > Bari B. Cunningham, MD < /a > < /span > Tags: Physician COVID-19 coronavirus Dermatology Infectious Disease Source Type: blogs

Fight Aging! Newsletter, November 15th 2021
This article will review the relationship between diabetes mellitus and AD as it relates to tau pathology. More understanding of the link between diabetes mellitus and AD could change the approach researchers and clinicians take toward both diseases, potentially leading to new treatments and preventative strategies in the future. Signaling from White Fat Tissue Contributes to Age-Related Hair Follicle Dysfunction https://www.fightaging.org/archives/2021/11/signaling-from-white-fat-tissue-contributes-to-age-related-hair-follicle-dysfunction/ Changes in fat tissue behavior in the skin take place with age,...
Source: Fight Aging! - November 14, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Signaling from White Fat Tissue Contributes to Age-Related Hair Follicle Dysfunction
Changes in fat tissue behavior in the skin take place with age, such as rising levels of inflammation and inflammatory signaling. These changes have a detrimental effect on the ability of hair follicles to produce hair. The growth of hair is a complicated process that cycles through repeated phases of growth (anagen), transition (catagen), and rest (telogen). Aging leads to progressive dysfunction in this process and loss of hair in late life. A better understanding of the details of this dysfunction may lead to interventions, such as those attempted here in mice, to change the signaling of fat tissue in aged skin and ther...
Source: Fight Aging! - November 11, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Cactus Spine-Inspired Sweat Collection Technology
A team of researchers at the Pohang University of Science & Technology in South Korea created a passive sweat collection device that is inspired by cactus spines. The device is intended as a means to collect sweat for biomedical analysis; for instance, to measure glucose levels in patients with diabetes. Having the ability to operate without a power source, the patch can passively collect tiny amounts of sweat efficiently, helping to unlock the potential of sweat analysis technology.    Sweat analysis holds enormous promise as a way to diagnose and monitor a variety of diseases. The basic idea is that a pa...
Source: Medgadget - November 9, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Materials Medicine Sports Medicine pohang Source Type: blogs

Simple Color Change Test Identifies Wound Infections
Researchers at the University of Bath in the UK, along with outside collaborators, have developed a simple color change test that rapidly indicates whether a wound is infected with harmful bacteria. The test works by detecting virulence factors released by the bacteria, which prompt a simple color change in a solution. The test could help clinicians to determine whether to prescribe antibiotics, and may help to avoid unnecessary prescribing. As the test can be administered at the point of care, and does not require expensive and time-consuming laboratory analysis, it may be very useful in low-resource or remote regions. ...
Source: Medgadget - November 5, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Diagnostics Materials Plastic Surgery uniofbath wound care Source Type: blogs

November 2021: Fleshy Lumps on the Scalp
Nausea and body aches. Probably COVID. Unvaccinated. Definitely COVID. After all, what else are we seeing?The 20-something young man was eating and talking on his phone. He passed the look test. His vitals were pristine, but he regaled me with myriad symptoms he had had for months. He hadn't taken any medicine. I was at a loss for what drove him to come to the emergency department. He thought for a minute and said, "I want to know why I have all these."He pointed to a spot on his head, which drew my attention to a fleshy lump. Then he moved his hair around, causing others to appear. "You can feel lots more,&...
Source: Lions and Tigers and Bears - November 1, 2021 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Merck, GlaxoSmithKline, AbbVie, Sanofi & Bristol Myers Squibb: Big Pharma ’s Extending Digital Health Reaches
A few weeks ago, we kickstarted a new series of articles contemplating the moves of pharmaceutical heavyweights in the digital health arena. The first batch of companies, Johnson & Johnson, Pfizer, Bayer and Novartis, seem to have some interest in remote healthcare solutions and DTx.  In this second article, we will explore which trends pharma giants Merck, GlaxoSmithKline, AbbVie, Sanofi and Bristol Myers Squibb are eyeing. Merck: big tech-friendly A big pharma company itself, Germany’s Merck hasn’t shied from teaming up with big tech companies in recent years as it aims to make a lasting footpri...
Source: The Medical Futurist - October 26, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine Biotechnology Future of Medicine Future of Pharma Health Sensors & Trackers Personalized Medicine Portable Medical Diagnostics Security & Privacy pharmaceutics 23andme philips big pharma Merck Source Type: blogs

Technology ’s impact on dermatology [PODCAST]
“During COVID, the medical training system had to adapt because people couldn ’t meet in person and even those that could didn’t have access to patients or facilities in the same capacity. However, the explosion of remote training tools that became available make this hybrid training method as good in many ways, and perhaps even preferableRead more …Technology’s impact on dermatology [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 22, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Dermatology Source Type: blogs