Fight Aging! Newsletter, February 8th 2021
This study was divided in two phases: CALERIE-1 and CALERIE-2. CALERIE-1 study was performed to assess the possible effects induced by a reduction of 10-30% of caloric intake on body composition parameters and lipid profile after 6 and 12 months in a population of middle-aged non-obese subjects. CALERIE-1 results showed an improvement in lipid and glycemic profile and a reduction in body weight (BW) and fat mass.
CALERIE-2 was the largest multi-center study on CRD. A total of 220 subjects were enrolled randomly with a 2:1 allocation into two subgroups: 145 in the CRD group and 75 in the ad libitum group. The CRD gro...
Source: Fight Aging! - February 7, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Further Investigations of Partial, Transient Cellular Reprogramming
Reprogramming cells from old tissues into induced pluripotent stem cells has the effect of reversing many of the epigenetic changes that are characteristic of age, thus restoring mitochondrial function and other aspect of cell behavior. This is a limited rejuvenation: it can't do much about DNA damage, and nor can it make cells clear persistent molecular waste that even youthful cells struggle with. Nonetheless, applying reprogramming to living mice has produced benefits to health, suggesting that if the process can be sufficiently controlled, then it may be a useful basis for therapy - perhaps globally forcing cells to be...
Source: Fight Aging! - February 3, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Understanding Leprosy on World Leprosy Day
Leprosy is a chronic and progressive disease that primarily affects the skin and peripheral nervous system. Leprosy has been with us for thousands of years. There is evidence of the disease as far back as 4000 BC, in ancient Egypt.[1] In 1873, Norwegian physician Dr. Gerhard Armauer Hansen discovered that leprosy was caused by a bacterium. [2] Today, we call this bacterium Mycobacterium leprae, and we often refer to leprosy as Hansen’s Disease, in honor of Dr. Hansen. While leprosy caused significant morbidity and mortality in the past, cases today are rare and are curable with proper treatment.
How Is Leprosy Transmitte...
Source: GIDEON blog - January 28, 2021 Category: Databases & Libraries Authors: Uri Blackman Tags: News Leprosy Source Type: blogs
Sarah ’ s Wheat Belly health and life transformation
Sarah’s story reminds us how the simple matter of diet can shape our lives for decades, affecting energy, body weight, emotional health–just about every aspect of our physical and social lives before we finally stumble on the right answers. After many years of struggling with poor health, relying on prescription medications that never addressed underlying causes, it therefore came as a surprise to Sarah that she could indeed achieve magnificent health without the drugs by simply following the diet programmed into human genetic code and supplementing nutrients that are deficient in modern life.
...
Source: Wheat Belly Blog - January 28, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open grain-free Inflammation joint pain wheat belly Source Type: blogs
ToeMate Nail Soak Fungus Treatment Kits
Why topical nail fungus (onychomycosis) treatment needs a device
Penetration
For the medication to penetrate and reach the infection through nail keratin (which absorbs water and repels water insoluble drugs) the treatment must be at least partially water soluble. The most effective way is to immerse the infected nails in an antimicrobial that is dissolved in water to give nails absorption time. Of the 125 or so treatments for nail fungus, only three are at least partially water soluble (Kerydin, Loceryl and ToeMate Nail Soak).
Scientifically, nail keratin is hydrophilic and Kobayashi et al 1999 found that the per...
Source: Medgadget - January 26, 2021 Category: Medical Devices Authors: ToeMate Tags: Sponsored Content Source Type: blogs
Microneedle Patch with Fluorescent Nanolabels Detects Antibodies in Skin
Researchers at the Washington University in St. Louis have developed a microneedle patch that can help to detect small amounts of antibodies in interstitial fluid. The painless technology could provide an alternative to blood draws for antibody tests, such as those used in the COVID-19 response. The new technology overcomes a bottleneck with many microneedle patch systems – their poor sensitivity. The researchers used “plasmonic-fluors,” fluorescent nanolabels, to detect protein biomarkers present in small amounts in interstitial fluid.
Blood draws are the go-to method for diagnostic testing, but they can ...
Source: Medgadget - January 25, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Medicine Pathology Public Health wustl Source Type: blogs
Hims & Hers CEO on IPO, Push into Primary Care, Target & More
By JESSICA DaMASSA, WTF HEALTH
On the eve of the finalization of their SPAC IPO and New York Stock Exchange debut as $HIMS, Hims & Hers CEO, Andrew Dudum, sat down with Jess DaMassa to talk about his wellness company’s transition into full-on healthcare provider. With new primary care, mental health care, and covid19 testing services launched as a result of the pandemic, Hims & Hers has expanded beyond their initial dermatology and sexual health core to provide telehealth-plus-pharmacy services for a growing range of chronic conditions, mental health issues, and everyday health concerns commonly tackled by...
Source: The Health Care Blog - January 21, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Tech Health Technology Jessica DaMassa WTF Health $HIMS Hers Hims & Hers IIPO Source Type: blogs
All you need to know about waterborne diseases
Waterborne diseases are contracted through exposure to contaminated water including drinking water, water used in food preparation, and swimming water.
They can be caused by bacteria, viruses, and parasites. Below is a partial list of waterborne disease pathogens, their microbial classification, and their resulting illnesses.
Classification
Microorganism
Disease
Bacterium
Campylobacter spp.
Campylobacteriosis
Bacterium
Escherichia coli
E. Coli Diarrhea
Bacterium
Legionella pneumophila
Legionnaires’ Disease
Bacterium
Salmonella enterica
Salmonellosis
Bacterium
Salmonella typhi
Typhoid fever
...
Source: GIDEON blog - January 14, 2021 Category: Databases & Libraries Authors: Kristina Symes Tags: Microbiology News Tips Source Type: blogs
The Paradoxical Under-employment of Rehab Physicians During the COVID-19 Pandemic
I used to joke that for all the hardships of being a physician, at least we had job security. Little did I know that a viral illness would put some physicians “on the bread line.”
The COVID-19 pandemic has negatively impacted the physician workforce in both anticipated and unanticpated ways. While stay-at-home orders decrease temporary demand for cosmetic and elective surgical procedures by dermatologists and orthopedic surgeons, inpatient rehabilitation facilities are also feeling the squeeze, though the number of patients who need their services are growing exponentially (due to post-COVID syndromes).
I...
Source: Better Health - January 10, 2021 Category: American Health Authors: Dr. Val Jones Tags: Uncategorized COVID-19 Disability Locum Tenens Long COVID Physiatry Physician Workforce PM&R Rehabilitation Physician Under-employment Unemployment Source Type: blogs
Notice: Dermal Fillers and Moderna Vaccine
The Aesthetic Society, the professional organization of plastic surgeons, shares information of three patients with dermal filler history experiencing localized facial swelling after receiving the Moderna COVID-19 vaccine. The cases were treated with antihistamines and/or steroids. No similar cases have been reported with the Pfizer vaccine.According toThe Aesthetic Society notice,“The incidents that have been reported are very rare, and these facial swelling reactions have been mild and responded quickly to oral steroids and/or oral antihistamines. None of the cases required the use of an EpiPen or hospitalization, none...
Source: What's New In Plastic Surgery? - January 6, 2021 Category: Cosmetic Surgery Source Type: blogs
Docs are ROCs: a simple fix for a “methodologically indefensible” practice in medical AI studies
By LUKE OAKDEN-RAYNER
Anyone who has read my blog or tweets before has probably seen that I have issues with some of the common methods used to analyse the performance of medical machine learning models. In particular, the most commonly reported metrics we use (sensitivity, specificity, F1, accuracy and so on) all systematically underestimate human performance in head to head comparisons against AI models.
This makes AI look better than it is, and may be partially responsible for the “implementation gap” that everyone is so concerned about.
I’ve just posted a preprint on arxiv titled “Docs ar...
Source: The Health Care Blog - December 11, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech AI Radiology Source Type: blogs
3 strategies for matching into a competitive specialty, even with a lower USMLE score
For applicants seeking to match into a competitive specialty, it can be challenging. In fact, it’s not uncommon for programs to receive over 100 applications for a single residency position. To sort through that many applications, many programs use filters. One type of filter is a USMLE“cut-off” score: applicants who don’t score above a […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 6, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/rajani-katta" rel="tag" > Rajani Katta, MD < /a > < /span > Tags: Education Dermatology Medical school Residency Source Type: blogs
Thanksgiving came early this year. I just didn ’t appreciate it.
I retired on June 30, 2020, after 32 years of solo practice as a dermatologist. Due to the pandemic, some say I was smart to retire when I did. But if I was so smart, I would have retired on February 28th. My practice was simple: three full-time employees, 1,300 square feet, no fancy surgeries […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 2, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/marc-l-frost" rel="tag" > Marc L. Frost, MD < /a > < /span > Tags: Physician Dermatology Source Type: blogs
Digital Otoscope Enhances Decision-Making and Improves Outcomes
Procedural equipment will help you make accurate diagnoses and formulate treatment plans. You want the equipment to work, be readily accessible, and be easy to clean and store. It's also nice when it fits in your pocket.You also want to be sure your staff is trained to use it. Not everyone in your department may want to break out the nasal endoscope for a quick ENT exam, as we discussed last month. (See post below.) But specialized ENT equipment may make your life a bit easier and improve patient outcomes. Using a digital otoscope to view the tympanic membrane is fast, easy, and safe. This particular model costs $24. ...
Source: The Procedural Pause - November 30, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Long COVID: 8 Ways Digital Health Can Address The Symptoms
Yes, the COVID-19 pandemic is long. Since the WHO characterised the virus’ spread as a pandemic in March, cases have been climbing; countries are facing a second wave and are entering lockdown 2.0; and many aspects of our current lifestyle will continue through 2021. But this isn’t what we mean by “long COVID.” This newly-minted term refers to patients experiencing long-term sequelae of a COVID infection.
It’s not an exact medical term as it is a patient-made one apparently first used by Elisa Perego in a tweet to describe her own experience. Additionally, two patients can have different #longcovid experiences...
Source: The Medical Futurist - November 17, 2020 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine E-Patients Health Sensors & Trackers Healthcare Design Healthcare Policy Portable Medical Diagnostics Telemedicine & Smartphones AI diabetes lumosity wearables sleep tracking Fitbit mental heal Source Type: blogs
