Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues.
Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease
https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/
With the caveat that mouse models of Alzheimer'...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Insurance profits over patients ’ lives: Doctors battle for proper care 33 times a week
“I can’t afford higher,” Bobby’s (identifying information changed) mom explains when asked about his low dose. As Bobby’s dermatologist, I prescribed Accutane, curing 80 percent of acne with a six-month course. Insurance denied, requiring doxycycline. I rarely give antibiotics, following World Health Organization (WHO) recommendations. Antibiotics build resistance and aren’t curative, resulting in more scarring.
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Insurance profits over patients’ lives: Doctors battle for proper care 33 times a week originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 16, 2023 Category: General Medicine Authors: Sheryl Hoyer, MD Tags: Physician Dermatology Source Type: blogs
Resibufogenin as a Senolytic Compound
Researchers continue to search for novel senolytic compounds, those capable of selectively destroying senescent cells while producing a minimal impact on other cells. In youth, senescent cells are rapidly cleared by the immune system, but this clearance falters with age, leading to an accumulating burden of senescence in tissues throughout the body. These lingering senescent cells secrete pro-growth, pro-inflammatory signals that are disruptive to tissue structure and function when sustained over the long term. The lasting presence of senescent cells contributes to the chronic inflammation of aging, as well as to the onset...
Source: Fight Aging! - July 13, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Prospect of Senotherapeutics to Treat Skin Aging
Will senolytic drugs to destroy senescent cells and senomorphic drugs to reduce the harmful senescence-associated secretory phenotype (SASP) turn out to improve on present poor approaches to treat skin aging in humans? Few groups appear motivated to find out. Those developing senotherapeutics as drugs focus on more serious concerns than skin aging, and are arguably right to do so, while those developing senotherapeutics as cosmetics have little incentive to conduct expensive, robust clinical trials of their products. Success in selling cosmetic products has little connection with whether or not the products actually work. ...
Source: Fight Aging! - July 11, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
How artificial intelligence (AI) is transforming dermatology diagnosis and treatment
The rise of artificial intelligence (AI) is no less than a modern revolution. As we progress in the digital age, the capabilities of AI continue to expand, facilitating advancements in countless fields. One such field is health care, where AI has the potential to significantly enhance diagnostic accuracy and treatment efficiency. A shining example of
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How artificial intelligence (AI) is transforming dermatology diagnosis and treatment originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 10, 2023 Category: General Medicine Authors: Hannah Kopelman, DO, MBA Tags: Tech Dermatology Source Type: blogs
Revealing the hidden impact of skin conditions
During my internal medicine residency, I rotated through various subspecialties, but the one that always gave me thought-provoking perspectives at the end of the day was dermatology. I was very excited to work in derma and learn how to treat basic clinical conditions like acne, hair fall, dermatitis, etc., at the back of my hand.
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Revealing the hidden impact of skin conditions originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 8, 2023 Category: General Medicine Authors: Dr. Natasha Khalid Tags: Conditions Dermatology Source Type: blogs
The truth behind overpriced medical laser devices: What physicians need to know
The medical aesthetic field is experiencing significant growth, with an expected market valuation of billions by 2023. As the demand for non-invasive aesthetic procedures rises, physicians are increasingly enticed by medical laser devices. However, this industry is plagued by underhanded sales tactics and excessively priced equipment, leaving physicians at a loss. The overpriced landscape of
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The truth behind overpriced medical laser devices: What physicians need to know originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 7, 2023 Category: General Medicine Authors: Emil Shakov, MD Tags: Physician Dermatology Source Type: blogs
Data Democracy! ‘Dr. Google’ (2023) Vs. ‘Every Man His Own Physician’ (1767)
BY MICHAEL MILLENSON
In the 18th-century, a pre-Google guide offered democratization of medical information
In 1767, as American colonists’ protestations against “taxation without representation” intensified, a Boston publisher reprinted a book by a British doctor seemingly tailor-made for the growing spirit of independence.
Talk about “democratization of health care information,” “participatory medicine” and “health citizens”! Every Man His Own Physician, by Dr. John Theobald, bore an impressive subtitle: Being a complete collection of efficacious and approved remedies for every disease...
Source: The Health Care Blog - July 7, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice Democritization of Care Healthcare Michael Millenson Participatory medicine Source Type: blogs
Fight Aging! Newsletter, July 3rd 2023
In this study, cultured adipose-derived stem cells (ASCs) were derived from subcutaneous white adipose tissue isolated from mice fed a normal diet. We performed senescence-associated-β-galactosidase (SA-β-gal) staining, real-time PCR, and Western blot to evaluate the levels related to cellular senescence markers.
The mRNA expression levels of senescence markers were significantly increased in the later passages of ASCs. We show that light activation reduced the expression of senescent genes, and SA-β-Gal in all cells at passages. Moreover, the light-activated ASCs-derived exosomes decrease the expression of senes...
Source: Fight Aging! - July 2, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Senescent Melanocytes Encourage Hair Growth
Why do moles tend to grow hair, even in older people who are well advanced in loss of hair growth elsewhere on the skin? Researchers here provide evidence for this to be due to signals secreted by senescent melanocyte cells. This may provide a path to encourage a reversal of hair loss in all of the various poorly-understood circumstances that lead to balding. Inducing an additional burden of cellular senescence in skin is not desirable, but a better understanding of exactly how the senescence-associated secretory phenotype (SASP) encourages hair growth could provide a more direct way to provide only the necessary signals t...
Source: Fight Aging! - June 30, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
RCM: Fixing the Old and Adjusting to the New
Revenue Cycle Management (RCM) is like a one of those huge Lego sculptures. From the outside it looks one thing, but upon further inspection there are a million tiny little pieces that fit together to create the whole. Having a well executed RCM strategy is crucial to keep your organization running because it impacts everything. When things are simple and easy to pay for, patients are happy, the staff is happy, and you are most definitely happy. But if any part is misaligned, the whole sculpture can be disformed or even fall apart. So how do we improve? How do we make our sculpture be more realistic? The key lies in optimi...
Source: EMR and HIPAA - June 29, 2023 Category: Information Technology Authors: Grayson Miller Tags: Administration Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Regulations Revenue Cycle Management Amy Brown AristaMD Authenticx Branden Barkema Brooke LeVasseur Clara Lambert Clarissa Ri Source Type: blogs
More than skin deep: the importance of culturally competent care in medical education
The very first patient I met in the rheumatology clinic at SUNY Downstate heard I was applying to medical school and pulled me close to her, saying, “I want you to feel the swelling in my hands.” She took great care to ensure I palpated each joint and appreciated the warmth, erythema, and “boggy” feeling
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More than skin deep: the importance of culturally competent care in medical education originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 26, 2023 Category: General Medicine Authors: Grace Shadid Tags: Education Dermatology Medical school Source Type: blogs
How to maximize your dermatology appointment for effective care
An office visit with a health care professional can seem like a race against time and money. With rising co-pays and shorter appointments, arriving prepared for a health care appointment will maximize the likelihood of addressing as many concerns as possible and developing a personalized treatment plan. Below are the ways you can prepare for
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How to maximize your dermatology appointment for effective care originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 17, 2023 Category: General Medicine Authors: Karen Ezenne and Albert Zhou, MD, PhD Tags: Physician Dermatology Source Type: blogs
Targeting Pro-Inflammatory Cytokine IL-17 to Slow Skin Aging
Researchers here report that a few cell types in aged skin begin to generate large amounts of IL-17, an inflammatory signal molecule. While the obvious suspect here is cellular senescence, as we know that senescent cells accumulate with age and energetically secrete pro-inflammatory signal molecules, this data suggests that this may not be the case, at least for this particular signal molecule in this particular tissue. The researchers show that blocking IL-17 slows the manifestations of skin aging. The challenge in this sort of approach is that inflammatory signal molecules are needed for the normal immune response to fun...
Source: Fight Aging! - June 16, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
What Is Medical Coding Automation And Its Potentials In Healthcare?
When it comes to the term ‘coding’, what comes to mind is probably programmers writing software. While this applies to the medical setting in the digital health age, traditionally, medical coding has referred to a specific process. It involves the conversion of medical records, generally from clinician’s texts, into structured codes based on a classification system for the appropriate patient diagnosis and relevant procedure.
The result is clinical information that is consistent and comparable over time and across healthcare departments. Such data can subsequently be used to inform relevant research, policies and,...
Source: The Medical Futurist - June 1, 2023 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF Artificial Intelligence in Medicine Medical coding clinical coding AI AI in medical coding AI in hospitals digital health Source Type: blogs
