Medsi Raises USD $10M in Debt-Financing Round to Onboard First 30,000 Mexican Customers Currently on the Waitlist for its “Health Assurance” Super App
Fast-expanding healthcare marketplace, Medsi, aims to solve big challenge of Latin American gap in access to affordable care via first-of-its-kind offering focused on the Mexico market first With only a tiny fraction of Mexicans having health insurance or access to the necessary credit or savings, a medical emergency can be a catastrophic event as evidenced by the recent COVID-19 pandemic that hit Mexico harder than the rest of North America. It’s why Medsi chose Mexico as its “ground zero.” Today, Medsi – a “fintech meets healthtech” marketplace that makes healthcare services, information, and pricing more ...
Source: EMR and HIPAA - February 3, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Affordable Care CAPEM Mexico Health IT Funding Health IT Fundings Health IT Investment Jose Pepe Cabrera Manuel Villalvazo Medsi Medsi Credit App Medsi’s 24/7 Medical Concierge™ Services Mexico H Source Type: blogs

Fight Aging! Newsletter, January 30th 2023
In conclusion, deletion of p16Ink4a cells did not negatively impact beta-cell mass and blood glucose under basal and HFD conditions and proliferation was restored in a subset of HFD mice opening further therapeutic targets in the treatment of diabetes. Communication Between Blood and Brain in Aging and Rejuvenation https://www.fightaging.org/archives/2023/01/communication-between-blood-and-brain-in-aging-and-rejuvenation/ As noted here, joining the circulatory systems of an old and young mouse results in some degree of rejuvenation in the old mouse. Where brain function is improved, researchers are inte...
Source: Fight Aging! - January 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Towards Microneedle Delivery of LNP-mRNA Gene Therapies for Skin Aging
The skin is arguably one of the easiest of the large organs in the body to target for delivery of gene therapies, via established microneedle approaches. Nonetheless, much of the initial thrust of gene therapy clinical development focused instead on the liver, one of the other more tractable targets. Most material injected into the bloodstream ends up in the liver, and a single injection is logistically easier than coverage of large amounts of skin via microneedle patches, among other reasons. Given the advent of messenger RNA (mRNA) encapsulated in lipid nanoparticles (either artificial or repurposed extracellular ...
Source: Fight Aging! - January 27, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Discover the reality of living with hidradenitis suppurativa [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! In this episode, we speak with Christopher Sayed, a dermatologist who has dedicated his career to studying and treating hidradenitis suppurativa (HS). HS is a condition that causes painful boils in areas like the underarms, groin, and around the breasts, and it can be Read more… Discover the reality of living with hidradenitis suppurativa [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 25, 2023 Category: General Medicine Authors: Tags: Podcast Dermatology Source Type: blogs

Can Tech Giants Take Over Healthcare?
Tech (and retail) giants have shown increasing interest in the healthcare sector in the past decade, and we’ve been discussing their advancement for years. They might have chosen somewhat different tactics, like Google investing heavily in AI with DeepMind and Verily, or Microsoft focusing on the EMR and cloud solutions, one way or another, billions of tech dollars have flown into these ventures. 2022, however, presented a new chapter: a number of major non-healthcare players decided to step in as primary care providers. It started with Amazon acquiring primary care provider One Medical for $3.9 billion reported in l...
Source: The Medical Futurist - January 24, 2023 Category: Information Technology Authors: Andrea Koncz Tags: Artificial Intelligence in Medicine Future of Medicine amazon digital health google microsoft primary care tech giants Future of healthcare tech giants in healthcare Source Type: blogs

Bonus Features – January 15, 2023 – 80% of consumers want a clearer process for dealing with billing errors, USCDI update would add 20 more elements, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Studies ONC released the Draft United States Core Data for Interoperability (USCDI) v4 and its accompanying Standards Bulletin. USCDI is a standardized set of health data classes and data elements that enables data exch...
Source: EMR and HIPAA - January 15, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT 3M Allina Health Ayble Health Cameron Deemer Castell CenTrak CloudWave Cone Health digital pathology DocGo Dr. B DrFirst Edifecs Elevate Addiction Services Franciscan Health GE Healthcare Gradient Health H Source Type: blogs

Is It Physical Assault to “Expose” Someone to Fentanyl?
Jeffrey A. SingerAlmost every week,reports appear in the local news describing how police officers, exposed to fentanyl in the air or by contact, lose consciousness and need reviving with the opioid overdose antidote naloxone. Their coworkers take them to a nearby emergency room, where they are evaluated and released.This unscientific hysteria reached a new level when police near Wilmington, North Carolina, addedassault charges to a suspect they arrested and charged with possessing and trafficking heroin, marijuana, and drug paraphernalia. Police added the assault charges because the suspect tossed the drugs...
Source: Cato-at-liberty - January 9, 2023 Category: American Health Authors: Jeffrey A. Singer Source Type: blogs

Fight Aging! Newsletter, January 2nd 2023
In conclusion, circulating monocytes in older adults exhibit increased expression of activation, adhesion, and migration markers, but decreased expression of co-inhibitory molecules. MERTK Inhibition Increases Bone Density via Increased Osteoblast Activity https://www.fightaging.org/archives/2022/12/mertk-inhibition-increases-bone-density-via-increased-osteoblast-activity/ Bone density results from the balance of constant activity on the part of osteoblasts and osteoclasts, the former building bone, the latter breaking it down. With advancing age, the balance of activity shifts to favor osteoclasts, pro...
Source: Fight Aging! - January 1, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Notes on the 2022 Longevity Summit at the Buck Institute
The Buck Institute recently hosted the 2022 Longevity Summit, and here find some notes on the event from a participant. The number of conferences dedicated to the field of longevity science is increasing steadily, year after year. The best are those in which one finds a mix of entrepreneurs, scientists, and investors, all networking to advance the state of the art in the treatment of aging as a medical condition. The Longevity Summit at the Buck Institute, a relatively short two-day geroscience and longevity biotech conference held on December 6-7, was nevertheless densely packed with new research - to the point w...
Source: Fight Aging! - December 28, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, December 12th 2022
In conclusion, selective removal of senescent dermal fibroblasts can improve the skin aging phenotype, indicating that BPTES may be an effective novel therapeutic agent for skin aging. Non-Dividing Neurons Do In Fact Become Senescent, Impairing Brain Function https://www.fightaging.org/archives/2022/12/non-dividing-neurons-do-in-fact-become-senescent-impairing-brain-function/ Cellular senescence is generally thought of as a characteristic of replicating cells; it is an end state reached when telomeres, reduced in length with each cell division, become too short. This is followed by programmed cell death...
Source: Fight Aging! - December 11, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Testing a Glutaminase Inhibitor to Clear Senescent Cells in Skin Models
In conclusion, selective removal of senescent dermal fibroblasts can improve the skin aging phenotype, indicating that BPTES may be an effective novel therapeutic agent for skin aging. Link: https://doi.org/10.18632/aging.204391 (Source: Fight Aging!)
Source: Fight Aging! - December 7, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Asynchronous Telemedicine Is Coming And Here Is Why It ’ s The Future Of Remote Care
Asynchronous telemedicine is one of those terms we will need to get used to in the coming years. Although it may sound alien, chances are you have been using some form of it for a while.  With the progress of digital health, especially due to the pandemic’s impact, remote care has become a popular approach in the healthcare setting. It can come in two forms: synchronous telemedicine and asynchronous telemedicine.  Synchronous refers to having discussions in real-time: the patient and the healthcare provider are connected with an audio or audio-visual link to have a live consultation.  Asynchro...
Source: The Medical Futurist - November 30, 2022 Category: Information Technology Authors: Andrea Koncz Tags: Telemedicine & Smartphones telehealth remote care Asynchronous telemedicine Source Type: blogs

Fight Aging! Newsletter, November 28th 2022
This study explored whether determining the gain or loss of specific taxa represent a more precise metric of healthy/unhealthy aging than summary microbiome statistics, such as diversity and uniqueness. We analyzed microbiome diversity and four measures of microbiome uniqueness in 21,000 gut microbiomes for their relationship with aging and health. We show that diversity and uniqueness measures are not synonymous; uniqueness is not a uniformly desirable feature of the aging microbiome, nor is it an accurate biomarker of healthy aging. Different measures of uniqueness show different associations with diversity and with mark...
Source: Fight Aging! - November 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

YAP and TAZ in Cell Structure and Cell Senescence
This scientific commentary describes an interesting join the dots exercise in which scientists link together a number of different topics that have shown up over the years in research into aging. Here, the Hippo pathway (activated by YAP and TAZ), the shape and maintenance of the nuclear envelope, inflammatory cGAS/STING signaling, and cellular senescence are all connected. Declining expression of YAP and TAZ occur with aging, for reasons to be explored, and that decline appears sufficient in and of itself to trigger the rest of the linked cascade of changes and consequent cellular senescence and tissue dysfunction. ...
Source: Fight Aging! - November 22, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Why does it take 10 years to diagnose this common disease?
Every day, patients with the same story walk into my office. Young people in their teens, 20s or 30s are exasperated and seeking help for constant painful boils that drain the pus in underarms, groin, and around breasts — a condition called hidradenitis suppurativa (HS). This disease often makes their lives a nightmare. Despite being Read more… Why does it take 10 years to diagnose this common disease? originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 15, 2022 Category: General Medicine Authors: Tags: Conditions Dermatology Source Type: blogs