RNA structures of coronavirus reveal potential drug targets
The SARS-CoV-2 coronavirus RNA genome structure was studied in detail by researchers from the University of Groningen, the International Institute of Molecular and Cell Biology in Warsaw, and Leiden University. The RNA structures are potential targets for the development of drugs against the virus. The results were published on 10 November as 'Breakthrough paper' in the journal Nucleic Acid Research. (Source: World Pharma News)
Source: World Pharma News - November 10, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
RNA structures of coronavirus reveal potential drug targets
(University of Groningen) The SARS-CoV-2 coronavirus RNA genome structure was studied in detail by researchers from the University of Groningen, the International Institute of Molecular and Cell Biology in Warsaw, and Leiden University. The RNA structures are potential targets for the development of drugs against the virus. The results were published on 10 November as 'Breakthrough paper' in the journal Nucleic Acid Research. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 10, 2020 Category: Infectious Diseases Source Type: news
LSU health team wins Best 2020 Radiology Image award
(Louisiana State University Health Sciences Center) AuntMinnie.com awarded Bradley Spieler, MD, Vice Chairman of Radiology Research and Associate Professor of Radiology, and Emma R. Schachner, PhD, Associate Professor of Cell Biology& Anatomy, at LSU Health New Orleans School of Medicine, the 2020 Best Radiology Image for their COVID-19 lung model project. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 6, 2020 Category: Infectious Diseases Source Type: news
Cell Biologist Angelika Amon Dies at 53
A "larger than life personality," Amon devoted her career to study the cell cycle and aneuploidy. Her research has shaped the field of cancer biology. (Source: The Scientist)
Source: The Scientist - November 4, 2020 Category: Science Tags: News & Opinion Source Type: news
UCLA researchers create millions of diverse T cells from a single blood stem cell
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a way to make mouse thymus organoids that can be grown in the lab, each one about 2 millimeters in size.The advance will enable them to follow the precise path by which T cells — critical players in the immune system — are formed from blood stem cells inside the thymus, a small gland in the middle of the chest.In 2017, UCLA ’sDr. Gay Crooks and her colleaguesdevelopeda lab-grown human thymus organoid— a cluster of cells that mimics the thymus. Using the organoid, her team was able tocoax human ...
Source: UCLA Newsroom: Health Sciences - October 30, 2020 Category: Universities & Medical Training Source Type: news
Hormone-guided self-organization
(Source: ScienceNOW)
Source: ScienceNOW - October 29, 2020 Category: Science Authors: Hines, P. J. Tags: Cell Biology, Development twis Source Type: news
Receptor kinase module targets PIN-dependent auxin transport during canalization
Spontaneously arising channels that transport the phytohormone auxin provide positional cues for self-organizing aspects of plant development such as flexible vasculature regeneration or its patterning during leaf venation. The auxin canalization hypothesis proposes a feedback between auxin signaling and transport as the underlying mechanism, but molecular players await discovery. We identified part of the machinery that routes auxin transport. The auxin-regulated receptor CAMEL (Canalization-related Auxin-regulated Malectin-type RLK) together with CANAR (Canalization-related Receptor-like kinase) interact with and phospho...
Source: ScienceNOW - October 29, 2020 Category: Science Authors: Hajny, J., Prat, T., Rydza, N., Rodriguez, L., Tan, S., Verstraeten, I., Domjan, D., Mazur, E., Smakowska-Luzan, E., Smet, W., Mor, E., Nolf, J., Yang, B., Grunewald, W., Molnar, G., Belkhadir, Y., De Rybel, B., Friml, J. Tags: Cell Biology, Development r-articles Source Type: news
Physical traits of cancer
The role of the physical microenvironment in tumor development, progression, metastasis, and treatment is gaining appreciation. The emerging multidisciplinary field of the physical sciences of cancer is now embraced by engineers, physicists, cell biologists, developmental biologists, tumor biologists, and oncologists attempting to understand how physical parameters and processes affect cancer progression and treatment. Discoveries in this field are starting to be translated into new therapeutic strategies for cancer. In this Review, we propose four physical traits of tumors that contribute to tumor progression and treatmen...
Source: ScienceNOW - October 29, 2020 Category: Science Authors: Nia, H. T., Munn, L. L., Jain, R. K. Tags: Medicine, Diseases, Online Only, Physics review Source Type: news
Cell biology gurus and UCF Bioimaging expert partner to crack 4th dimension secrets
(University of Central Florida) Cell biologists at the University of Illinois at Urbana-Champaign and Bar-Ilan University at Israel and a bioimaging expert at the University of Central Florida are teaming up in what they hope may lead to a major breakthrough in understanding of the three-dimensional organization of the nucleus over time and their role in certain diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 28, 2020 Category: International Medicine & Public Health Source Type: news
Oxygen-sensing mechanisms across eukaryotic kingdoms and their roles in complex multicellularity
Oxygen-sensing mechanisms of eukaryotic multicellular organisms coordinate hypoxic cellular responses in a spatiotemporal manner. Although this capacity partly allows animals and plants to acutely adapt to oxygen deprivation, its functional and historical roots in hypoxia emphasize a broader evolutionary role. For multicellular life-forms that persist in settings with variable oxygen concentrations, the capacity to perceive and modulate responses in and between cells is pivotal. Animals and higher plants represent the most complex life-forms that ever diversified on Earth, and their oxygen-sensing mechanisms demonstrate co...
Source: ScienceNOW - October 22, 2020 Category: Science Authors: Hammarlund, E. U., Flashman, E., Mohlin, S., Licausi, F. Tags: Biochemistry, Cell Biology, Online Only review Source Type: news
Origins and evolution of hypoxia response
(Source: ScienceNOW)
Source: ScienceNOW - October 22, 2020 Category: Science Authors: Vignieri, S. Tags: Biochemistry, Cell Biology twis Source Type: news
Science Saturday: Mining the molecular origins of breast cancer for new cures
October is Breast Cancer Awareness Month, a time to focus on new strategies for prevention and early detection. Mayo Clinic Center for Regenerative Medicine and Mayo Clinic Cancer Center support stem cell biology research to uncover the molecular origins of breast cancer in order to bring new cures to the practice. Answering what are the causes of breast cancer at [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - October 17, 2020 Category: Research Source Type: news
Cytology/HPV Co-testing for Detection of Cervical Cancer Cytology/HPV Co-testing for Detection of Cervical Cancer
This study evaluated the contributions of liquid-based cytology and HPV testing in cervical cancer screening co-testing. Is the cytology component still of value?American Journal of Clinical Pathology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 15, 2020 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news
A cellular sense of space and pressure
(Source: ScienceNOW)
Source: ScienceNOW - October 15, 2020 Category: Science Authors: Shen, Z., Niethammer, P. Tags: Cell Biology perspective Source Type: news
Cells drop a bomb on pathogens
(Source: ScienceNOW)
Source: ScienceNOW - October 15, 2020 Category: Science Authors: Scanlon, S. T. Tags: Cell Biology twis Source Type: news
