NHS must adapt for rise in cystic fibrosis survival rates
The number of people living with cystic fibrosis into adulthood in the UK is expected to increase by as much as 80% by 2025, according to a Europe-wide survey. (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - March 20, 2015 Category: Nursing Source Type: news

Study may explain low blood oxygen levels for cystic fibrosis patients with infected lungs
(Source: St. Michael's Hospital News and Media)
Source: St. Michael's Hospital News and Media - March 19, 2015 Category: Hospital Management Tags: Hospital News Source Type: news

Dramatic rise expected in adults living with cystic fibrosis
The number of people living with cystic fibrosis into adulthood is expected to increase dramatically by 2025, prompting calls for the development of adult cystic fibrosis services to meet the demand. People living with cystic fibrosis have previously had low life expectancy, but improvements in treatments and care in the last three decades have led to an increase in survival with almost all children now living to around 40 years. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 19, 2015 Category: Science Source Type: news

Scientists grow 'mini-lungs' to aid the study of cystic fibrosis
(University of Cambridge) Scientists at the University of Cambridge have successfully created 'mini-lungs' using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 19, 2015 Category: Biology Source Type: news

Vertex’s Kalydeco obtains FDA approval to treat CF in children
Vertex Pharmaceuticals has received approval from the US Food and Drug Administration (FDA) for its Kalydeco (ivacaftor) to treat cystic fibrosis (CF) in children aged between two and five years. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - March 19, 2015 Category: Pharmaceuticals Source Type: news

Experts predict sharp rise in cystic fibrosis cases by 2025
50% rise in cases over next decade in Western EuropeRelated items from OnMedicaNewborns screened for four additional genetic conditionsDrug boosts bone density in cystic fibrosisLung transplantation leads to good outcome for cystic fibrosis Better use should be made of current cystic fibrosis treatments Babies with cystic fibrosis live longer in the EU (Source: OnMedica Latest News)
Source: OnMedica Latest News - March 19, 2015 Category: UK Health Source Type: news

Irish people with cystic fibrosis expected to live longer
Debilitating illness set to become disease of adults predominantly, rather than children (Source: The Irish Times - Health)
Source: The Irish Times - Health - March 18, 2015 Category: Consumer Health News Source Type: news

Incidence of cystic fibrosis in Irish to rise up to 65% by 2025
Debilitating illness set to become disease of adults predominantly, rather than children (Source: The Irish Times - Health)
Source: The Irish Times - Health - March 18, 2015 Category: Consumer Health News Source Type: news

Study may explain low blood oxygen for cystic fibrosis patients with infected lungs
A new bodily process found in mice may explain why blood oxygen levels are lower for patients with cystic fibrosis when they get a lung infection. "Our findings indicate that strategies aimed at restoring or activating the CFTR protein in patients with lung infection, particularly those with cystic fibrosis, might help improve blood oxygen levels and improve circulation," said one researcher. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 18, 2015 Category: Science Source Type: news

Study may explain low blood oxygen for cystic fibrosis patients with infected lungs
(St. Michael's Hospital) Researchers have defined a new bodily process in mice that may explain why blood oxygen levels are lower for patients with cystic fibrosis when they get a lung infection. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 18, 2015 Category: Biology Source Type: news

AbbVie Partners with Take A Breather Foundation to Fulfill Wishes for...
Take A Breather Foundation Fulfills Wishes Exclusively for Children Living with Cystic Fibrosis (CF).(PRWeb March 17, 2015)Read the full story at http://www.prweb.com/releases/cysticfibrosis/takeabreather/prweb12581803.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - March 17, 2015 Category: Pharmaceuticals Source Type: news

New cystic fibrosis research takes aim at deadly pathogen
(University of Texas at Austin) A new method of testing the most common cause of life-threatening infection in people with cystic fibrosis could improve efforts to study and combat the illness. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 17, 2015 Category: Biology Source Type: news

Autism-related genes linked to cognitive ability
Conclusion This study has found some small associations between common genetic variations linked to ASD and cognitive performance in the general population. Even where an association was found between genetic risk score and cognitive performance, the effect was very small. Less than 0.5% of the variability in people’s cognitive scores in the main study sample was explained by their ASD genetic risk score. The link between ASD genetic risk score and cognitive performance were only found in two of the three population samples assessed. This may be due to different age groups of participants, or to different cognitive...
Source: NHS News Feed - March 11, 2015 Category: Consumer Health News Tags: Genetics/stem cells Mental health Neurology Source Type: news

Unyielding Tenacity
The true strength and tenacity within ourselves are the sole make up of the people who hold us up, believe in us, and forbid to give up the fight when we are in need of saving. As I sit across from one of my doctors at my last appointment, I was overcome with the emotional realization that I am not in this alone. As I made light-hearted jokes about the future and talked about the tentative plans ahead, I knew the only reason I got to where I am today wasn't from me fighting cystic fibrosis alone, but from the multitude of doctors, nurses, pharmacists, friends, family members, and complete strangers holding me up, believin...
Source: Healthy Living - The Huffington Post - March 10, 2015 Category: Consumer Health News Source Type: news

ABC transporters explored in UK conference
(Biochemical Society) ABC transporters -- the protein superfamily involved in tumor resistance, cystic fibrosis and numerous inherited diseases -- will be explored in an upcoming UK conference.ATP Binding Cassette Transporters: From Mechanism to Organism takes place April 16-18, 2015, at the University of Chester, UK. Early bird registration closes on March 18, 2015. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 6, 2015 Category: Biology Source Type: news

New virtual research centres to break new ground in cystic fibrosis science and care
The development of new drugs to treat the most common cause of cystic fibrosis, a genetic defect (or mutation) carried by around 90 per cent of people living with the disease in the UK, will be helped by the creation of a new virtual Strategic Research Centre (SRC) led by the University of Bristol. (Source: University of Bristol news)
Source: University of Bristol news - March 6, 2015 Category: Universities & Medical Training Tags: Grants and Awards, Research; Institutes, Elizabeth Blackwell, Faculty of Medical and Veterinary Sciences, School of Physiology and Pharmacology, Faculty of Medical and Veterinary Sciences; Press Release Source Type: news

'Life-prolonging' research for cystic fibrosis patients underway
Preventing lung infections in childhood could stop later life-threatening infections for people with cystic fibrosis (CF), according to recent research. Scientists are investigating how bacteria found in children with CF can disarm their natural defence mechanisms, making it easier for more virulent bacteria to infect their airways. By the time many CF patients reach adulthood, they have already contracted the chronic Pseudomonas aeruginosa bacterial strain, which can cause extensive and eventually fatal damage to the lungs. The infection is currently extremely difficult to treat effectively. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 5, 2015 Category: Science Source Type: news

The Air of Fragility
Perfectly spun, a delicate crystalized beauty in an abundance of colors, and a unique simplicity that is born from the same air we breathe. But held too tightly or for too long between your fingers and it withers to nothing, leaving only a hint of its existence on your fingertips. Our lives are spun together like that of cotton candy. Our existence dances upon the air that spins beneath each breath we take, inspiring and shaping every moment we live into a beautiful web of beauty, and giving color to our unique journey. Its simple beauty is unmistakable. Yet, it is as fragile as spun sugar bound together by air. When we a...
Source: Healthy Living - The Huffington Post - March 2, 2015 Category: Consumer Health News Source Type: news

Chile's president visits teen who asked to die
14-year-old girl shocked country by pleading on YouTube for the leader to let doctors euthanize her because she is tired of her struggle with cystic fibrosis (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - March 1, 2015 Category: Consumer Health News Source Type: news

Cystic Fibrosis Market in Europe Resorts to Public Awareness Campaigns...
Researchmoz.us announces that a new market research report is available in its catalogue: Cystic Fibrosis Market in Europe(PRWeb February 27, 2015)Read the full story at http://www.prweb.com/releases/2015/03/prweb12549117.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - February 27, 2015 Category: Pharmaceuticals Source Type: news

Chile government rejects Valentina Maureira's plea for euthanasia
Chile's government on Thursday rejected a 14-year-old girl's plea who suffered from cystic fibrosis to let her 'sleep forever' and be euthanized. (Source: the Mail online | Health)
Source: the Mail online | Health - February 27, 2015 Category: Consumer Health News Source Type: news

Chilean girl with cystic fibrosis tells president: Let me die
SANTIAGO (Reuters) - A 14-year old Chilean girl with cystic fibrosis has asked to be allowed to die in a film she made pleading with President Michelle Bachelet to authorize her euthanasia. (Source: Reuters: Health)
Source: Reuters: Health - February 26, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

Garlic extract could help cystic fibrosis patients fight infection
(University of Edinburgh) A chemical found in garlic can kill bacteria that cause life-threatening lung infections in people with cystic fibrosis, research suggests. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 24, 2015 Category: Biology Source Type: news

Genetic pathways linked to CF disease severity pinned down
Mutation of one gene is all it takes to get cystic fibrosis, but disease severity depends on many other genes and proteins. For the first time, researchers identified genetic pathways that play major roles in why one person with CF might have severe symptoms while another person might not. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 23, 2015 Category: Science Source Type: news

Effect of Magnetic Fields on Cystic Fibrosis PathogensEffect of Magnetic Fields on Cystic Fibrosis Pathogens
Could exposure to extremely low frequency magnetic fields influence growth and biofilm formation by pathogens which cause chronic lung infections in cystic fibrosis patients? Future Microbiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 23, 2015 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

A link between cystic fibrosis and arsenic poisoning?
We report and comment on medical innovations and advances – from bench to bedside – touching on scientific, business and policy issues. Our ranks include science writers, physicians, lab researchers, market analysts and others inside and outside the hospital. Research in Bangladesh suggests that arsenic poisoning can cause cystic-fibrosis-like illness, quite aside from the classic genetic disease. (Photo: Nadia Shobnam) By Nancy Fliesler Boston Children's HospitalNews Well, Vector Blog, Big Data, Blogread more (Source: Mass Device)
Source: Mass Device - February 19, 2015 Category: Medical Equipment Authors: MassDevice Tags: Vector Blog Source Type: news

Mucus retained in cystic fibrosis patients' cells leads to potentially deadly infections
Cystic fibrosis mucus actually gets stuck inside some of the cells that create it, rather than simply becoming stuck on the outside linings of organs, researchers have found, which can increase the risk of deadly infection for the patient. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 18, 2015 Category: Science Source Type: news

Arkansas Reaches Settlement in Cystic Fibrosis Drug Suit
Arkansas Medicaid officials have reached a legal settlement to resolve claims the state denied patients an expensive cystic fibrosis therapy made by Vertex Pharmaceuticals because of its cost. (Source: WSJ.com: Health)
Source: WSJ.com: Health - February 6, 2015 Category: Pharmaceuticals Tags: PAID Source Type: news

Appearances Can Be Deceiving
I was attending a 50th birthday party for a friend of mine, when I struck up a conversation with someone I had never met. The conversation, of course, was with a woman who seemed genuinely interested in my quest to make air travel safer for those with food allergies. I told her how my family often receives dirty looks from other passengers when we pre-board a plane to wipe down the area for nut residue. I discussed how some people have laughed when asked not to open nut containers in the confined environment of an airplane. It is often hard to convey the seriousness of a life-threatening food allergy because it is a mostl...
Source: Healthy Living - The Huffington Post - January 23, 2015 Category: Consumer Health News Source Type: news

A Case of Cholera Imported From Haiti
Cholera, caused by Vibrio cholerae, is an acute and sudden-onset diarrheal disease that can result in profound dehydration because of excessive loss of water and electrolytes. Severe infections, if untreated, can lead to hypovolemic shock and death within 18 to 24 h. The virulence of V. cholerae is due to the production of cholera toxin that binds to enterocytes and eventually leads to the activation of the CFTR (cystic fibrosis transmembrane conductance regulator) gene, resulting in the massive efflux of water and electrolytes into the small bowel. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 20, 2015 Category: Microbiology Authors: Eric M. Sachinwalla, Carolyn Fernandes, Raghava Potula, Ming Zhang, Byungse Suh, Allan L. Truant Tags: Case Report Source Type: news

The Precipice
Our lives are filled with monumental precipices that impact the course of our journey. As we look out towards the horizon, we can see the moments, experiences, and choices that have all led us to this very moment in our lives. I find myself at the edge of a new precipice. For the last month I have been standing at the edge, terrified and resistant to take the next leap. I've been merely free falling: desperate to cling to the life I've had, the body I could trust, and resistant to face the realities of the future. Decisions and choices consume me that will impact every part of my life. I would be foolish to say that cys...
Source: Healthy Living - The Huffington Post - January 20, 2015 Category: Consumer Health News Source Type: news

Could 'DNA editing' lead to designer babies?
Conclusion This laboratory research using sperm and egg cells from mice demonstrates the use of a system to produce targeted alterations in the DNA – a process the media like to call “genetic editing”. The editing happened just before the genetic material of the egg and sperm cell fuse together. The system makes use of an enzyme (Cas9) capable of cutting bonds within DNA, and a “guide” molecule targeting it to the correct genetic location. So far, the techniques have only been tested in animals, and for “editing out” a small number of genes. However, though this is very earl...
Source: NHS News Feed - January 19, 2015 Category: Consumer Health News Tags: Genetics/stem cells Medical practice Source Type: news

Discovery of new signaling intermediates provides clues to novel therapies in pancreatitis
Signaling initiated by pancreatic digestive enzyme-producing (acinar) cells is essential to development of both pain and inflammation in pancreatitis, according to research. Pancreatitis is a common disorder that complicates many ailments, including cystic fibrosis and alcoholism. Few therapies exist, and management of the severe pain associated with inflammation is a major obstacle that often requires strong narcotics. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 15, 2015 Category: Science Source Type: news

Top 10 Medical Research Issues and Trends to Watch in 2015
At FasterCures, we are always thinking about ways to innovate the medical research system so that better treatments and cures get to patients faster. Read below to find out the top 10 issues and trends that we are watching this year: Crossing the aisle for cures. Kicking off 2015 will likely be the release of a draft of the 21st Century Cures legislation the U.S. House Energy & Commerce Committee has been developing under the leadership of Chairman Fred Upton and Representative Diana DeGette. The process itself has been a rare bright spot of comity and bipartisanship in the Congress, and a positive undertaking by memb...
Source: Science - The Huffington Post - January 15, 2015 Category: Science Source Type: news

Diagnosis of Allergic Bronchopulmonary AspergillosisDiagnosis of Allergic Bronchopulmonary Aspergillosis
Allergic bronchopulmonary aspergillosis occurs in patients with bronchial asthma or cystic fibrosis. This case series explores its clinical presentation and diagnostic challenges. Future Microbiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 9, 2015 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

KaloBios drops lung infection drug, shares plunge
(Reuters) - KaloBios Pharmaceuticals Inc said it would discontinue the development of its drug for lung infections in cystic fibrosis patients after it failed in a mid-stage study, sending the company's shares down 62 percent in extended trading. (Source: Reuters: Health)
Source: Reuters: Health - January 6, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

Op-Ed Contributor: Stop Subsidizing Big Pharma
Venture philanthropy risks benefiting companies, not patients. (Source: NYT Health)
Source: NYT Health - January 6, 2015 Category: Consumer Health News Authors: By LLEWELLYN HINKES-JONES Tags: Copyrights and Copyright Violations Corporate Taxes Drugs (Pharmaceuticals) Science and Technology Cystic Fibrosis Foundation Research Vertex Pharmaceuticals Inc Biotechnology and Bioengineering Tax Credits, Deductions and Exemptions Phi Source Type: news

Newborns screened for four additional genetic conditions
Same blood used to test for cystic fibrosis and sickle cell disease will be usedRelated items from OnMedicaLeading the way with NHS Screening ProgrammesDoctors call for cardiac screening in the youngBabies with cystic fibrosis live longer in the EUNewborn screening for lethal genetic disorder worksBabies to be screened for rare inherited conditions (Source: OnMedica Latest News)
Source: OnMedica Latest News - January 5, 2015 Category: UK Health Source Type: news

The Gift of Life
The worth and meaning of a gift do not come from the size of the box, its monetary value, or even the ribbon that adorns it. Its meaning comes from how it makes you feel inside as the recipient and as the giver. The greatest gifts are not boxes filled with things, but beautiful presents that hold so much more: love, kindness, selflessness, and gratitude. They all make up the beautiful gift of life. A Miraculous Gift I have received the most beautiful of gifts. This gift cannot fit in a box, nor can it merely be purchased: It is one of a kind and irreplaceable. What is this magnificent gift? My life. A month ago, cystic...
Source: Healthy Living - The Huffington Post - December 31, 2014 Category: Consumer Health News Source Type: news

FDA Expands Use of Ivacaftor (Kalydeco) for Cystic FibrosisFDA Expands Use of Ivacaftor (Kalydeco) for Cystic Fibrosis
The agency has approved the CFTR potentiator for use in children aged 6 years and older with cystic fibrosis who have the R117H mutation. FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 31, 2014 Category: Consumer Health News Tags: Pulmonary Medicine News Alert Source Type: news

Vertex cystic fibrosis drug approved for another 500 U.S. patients
The U.S. Food and Drug Administration has approved Kalydeco by Vertex Pharmaceuticals for use in about 500 more cystic fibrosis patients than previously. Kalydeco is the Boston pharmaceutical company's only approved drug, following it's decision last year to discontinue its hepatitis C drug due to competition. The drug is approved to treat several different gene mutations that cause the disease in about 1,150 patients who make up about 4 percent of CF patients in the U.S. The new approval for patients… (Source: bizjournals.com Health Care:Hospitals headlines)
Source: bizjournals.com Health Care:Hospitals headlines - December 29, 2014 Category: Hospital Management Authors: Don Seiffert Source Type: news

Cystic Fibrosis Market 2015 to 2019 Global New Research Report at...
Global Cystic Fibrosis Market 2015-2019 is a new industry research report which profiles key players like Actavis, Novartis, Gilead Sciences, Vertex Pharmaceuticals and F Hoffmann-La Roche.(PRWeb December 27, 2014)Read the full story at http://www.prweb.com/releases/cystic-fibrosis-market/research-2019/prweb12416068.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - December 27, 2014 Category: Pharmaceuticals Source Type: news

Cystic Fibrosis patient's festive wish to go swimming with friends and live to be a vet
EXCLUSIVE: Olivia Dein, from north London, has a simple wish this Christmas - she just wants to be well, like her little brother, Dylan, and sister, Jessica. (Source: the Mail online | Health)
Source: the Mail online | Health - December 24, 2014 Category: Consumer Health News Source Type: news

Commercial DNA Testing May Cause Harm, Scientific Studies Show (if You Read Through to the Study Limitations at the End)
A year after the US Food and Drug Administration urged 23andMe to stop the marketing of its personal genome test in the United States, the world's largest direct-to-consumer genetics company relaunched the test in Canada and the United Kingdom. "Find out how your genetics relate to things like abnormal blood clotting, cystic fibrosis or response to certain medications." [italics added] "Keep in mind that many conditions and traits are influenced by multiple factors. Our reports are intended for informational purposes only and do not diagnose disease or illness." The UK website of 23andMe opens with ...
Source: Science - The Huffington Post - December 22, 2014 Category: Science Source Type: news

Resistance to anti-viral drug may be more likely in cystic fibrosis patients
Following lung transplantation, resistance to the anti-viral drug ganciclovir may be more likely in cystic fibrosis patients, scientists report. Ganciclovir is given to lung transplant patients to protect against a life-threatening virus that is common after transplantation, and reduces mortality due to the virus from 34 percent to between 3 and 6 percent. But between 5 percent and 10 percent of patients infected with the virus have strains that are resistant to the drug. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 18, 2014 Category: Science Source Type: news

Resistance to anti-viral drug may be more likely in cystic fibrosis patients
(Loyola University Health System) Following lung transplantation, resistance to the anti-viral drug ganciclovir may be more likely in cystic fibrosis patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 18, 2014 Category: Global & Universal Source Type: news

Today's Patience Is Tomorrow's Possibility
Patience is not an entity in and of itself, but is a process, the act of learning to embrace a state of mind. It's something that must be practiced, embodied, and given room to grow. I must have patience for today, for the days ahead, and a steadfast appreciation for days past and how they have molded me. I would be foolish to tell all of you that I haven't had moments this week when I've lost sight of myself and felt a complete wreck: distraught with emotion for the future and the life I called my own a mere few weeks ago. The devastation that cystic fibrosis has caused in just a short time is unfathomable. I feel as if...
Source: Healthy Living - The Huffington Post - December 12, 2014 Category: Consumer Health News Source Type: news

Uh Oh, It's Flu Season! What You Need to Know About Flu Vaccination
Media reports from just about every corner of the country are cautioning that Americans could be in for a particularly intense flu season this year, with many medical experts encouraging folks not to delay getting their flu shots. The flu season is not only here -- it could last until as late as May of next year according to the CDC. With this in mind, it is helpful to review a few basics that could help keep you, your family and your friends and neighbors feeling at their best during this winter's seasonal outbreaks of the flu. Who's at Risk? The flu is a respiratory infection that can cause serious, sometimes life-thr...
Source: Healthy Living - The Huffington Post - December 12, 2014 Category: Consumer Health News Source Type: news

Recent Advances in the Management of Cystic FibrosisRecent Advances in the Management of Cystic Fibrosis
What new therapies are available for the management of cystic fibrosis? Archives of Disease in Childhood (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 4, 2014 Category: Consumer Health News Tags: Pediatrics Journal Article Source Type: news

DNA-screening test 23andMe launches in UK after US ban
The Google-backed genotyping service can screen for common genetic diseases such as cystic fibrosis or sickle cell anaemiaGenetic testing company 23andMe is launching its personal genome service in the UK after it was banned in the US.The service allows people to send their saliva in a testing kit to have their DNA screened for genes associated with certain inherited conditions, such as cystic fibrosis or sickle cell anaemia, and other genetic markers relating to parts of their lives and ancestry. Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - December 2, 2014 Category: Science Authors: Samuel Gibbs Tags: Google Technology Science UK news Health Genetics Research and development Biology Healthcare industry Business NHS Source Type: news