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Drug that improves blood flow may help find cause of exercise intolerance in cystic fibrosis
(Medical College of Georgia at Georgia Regents University) A little white pill may help scientists learn why patients with cystic fibrosis have less exercise capacity than their peers, even if their lungs are relatively healthy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 2, 2014 Category: Global & Universal Source Type: news

SNOT-22 Helps Identify CF Patients With Nasal PolypsSNOT-22 Helps Identify CF Patients With Nasal Polyps
The SNOT-22 questionnaire can help identify cystic fibrosis (CF) patients with subclinical nasal polyps, researchers from Canada report. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 29, 2014 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Patients with Cystic Fibrosis Are Living Longer (FREE)
By Kelly Young Edited by Jaye Elizabeth Hefner, MD Survival among patients with cystic fibrosis significantly improved between 2000 and 2010, according to a study in the Annals of Internal Medicine.Researchers studied a cohort of roughly … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 19, 2014 Category: Primary Care Source Type: news

Cystic fibrosis doesn't have to define you
Breathe in. (Source: CNN.com - Health)
Source: CNN.com - Health - August 18, 2014 Category: Consumer Health News Source Type: news

Man with cystic fibrosis becomes champion BODYBUILDER
James Boudreau, 29, from Michigan, U.S, has a lung capacity of just 48 percent and sleeps with an oxygen mask at night to prevent potentially fatal infections. (Source: the Mail online | Health)
Source: the Mail online | Health - August 18, 2014 Category: Consumer Health News Source Type: news

Annals of Internal Medicine tip sheet for Aug. 19, 2014
(American College of Physicians) The Aug. 19 issue of Annals of Internal Medicine contains the following articles: 'Opinion: Ebola-stricken American volunteers deserve special treatment'; 'Opinion: Ebola virus highly unlikely to spread in US'; 'Longer life expected for children born and diagnosed with cystic fibrosis in 2010'; and 'Atypical antipsychotic drug use increases risk for acute kidney injury.' (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 18, 2014 Category: Infectious Diseases Source Type: news

New X-ray imaging developed by scientists
(Monash University) Scientists have developed an X-ray imaging system that enables researchers to see 'live' how effective treatments are for cystic fibrosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 15, 2014 Category: Global & Universal Source Type: news

Cystic fibrosis mucus defect present at birth, study shows
Mucus is key to keeping our lungs clean and clear of bacteria, viruses, and other foreign particles that can cause infection and inflammation. When we inhale microbes and dust, they are trapped in the mucus and then swept up and out of the lungs via a process called mucociliary transport. New research shows that cystic fibrosis causes a specific defect in this process, reducing the ability to clear particles and germs out of the airway. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 14, 2014 Category: Science Source Type: news

ChanTest Announces a Global Campaign to Share New Findings and...
Cystic fibrosis continues to be devastating for many people around the world. ChanTest is participating in global efforts to identify solutions – and publishing a new white paper to share these...(PRWeb August 14, 2014)Read the full story at http://www.prweb.com/releases/2014/08/prweb12094221.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - August 14, 2014 Category: Pharmaceuticals Source Type: news

CF mucus defect present at birth
(University of Iowa Health Care) New research by University of Iowa scientists shows that cystic fibrosis (CF), a life-shortening, inherited condition that affects about 30,000 Americans, causes abnormalities in airway mucus that impairs the ability to clear particles and germs out of the airway. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 14, 2014 Category: Global & Universal Source Type: news

Business Briefing: Lung Transplant Device Receives Federal Approval
The Food and Drug Administration said Tuesday that the Xvivo Perfusion System could lead to more successful transplants of lungs for people with cystic fibrosis and other deadly respiratory diseases. (Source: NYT Health)
Source: NYT Health - August 12, 2014 Category: Consumer Health News Authors: By THE ASSOCIATED PRESS Tags: Cystic Fibrosis Respiratory System Food and Drug Administration Source Type: news

US FDA approves lung preservation machine
The approval of the XVIVO Perfusion System could lead to more successful transplants of lungs for people with cystic fibrosis and other deadly respiratory diseases. (Source: The Economic Times)
Source: The Economic Times - August 12, 2014 Category: Consumer Health News Source Type: news

I have cystic fibrosis but won't let it beat me
TIM WOTTON looks like an ordinary 43-year-old. (Source: Daily Express - Health)
Source: Daily Express - Health - August 12, 2014 Category: Consumer Health News Source Type: news

'I have cystic fibrosis but won't let it beat me'
BORN with the genetic disease cystic fibrosis, Tim Wotton has defied the odds all his life (Source: Daily Express - Health)
Source: Daily Express - Health - August 11, 2014 Category: Consumer Health News Source Type: news

Synthetic molecule makes cancer self-destruct
A molecule that can cause cancer cells to self-destruct by ferrying sodium and chloride ions into the cancer cells has been developed by scientists. These synthetic ion transporters confirm a two-decades-old hypothesis that could point the way to new anticancer drugs while also benefiting patients with cystic fibrosis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 11, 2014 Category: Science Source Type: news

Synthetic molecule makes cancer self-destruct
(University of Texas at Austin) Researchers from The University of Texas at Austin and five other institutions have created a molecule that can cause cancer cells to self-destruct by ferrying sodium and chloride ions into the cancer cells. These synthetic ion transporters, described this week in the journal Nature Chemistry, confirm a two-decades-old hypothesis that could point the way to new anticancer drugs while also benefitting patients with cystic fibrosis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 11, 2014 Category: Cancer & Oncology Source Type: news

Picturing pain
The pain of loneliness. The pain of post-traumatic stress. The pain of spinal stenosis, of uterine fibroids, of mortality. So how does someone explain one’s pain to another person, to make it real for someone else? By drawing it. To help UCLA medical students understand the experience of pain and illness and to reinforce in them that, as physicians, they must treat the person and not just the disease, “Pain,” an exhibition of postcards drawn by patients, has been put on display in UCLA’s David Geffen School of Medicine’s Gallery at the Learning Resource Center through August 31. For the exhib...
Source: UCLA Newsroom: Health Sciences - August 6, 2014 Category: Universities & Medical Training Source Type: news

Vertex obtains receives European approval for cystic fibrosis oral medicine
The European Commission has approved Vertex Pharmaceuticals' oral medicine Kalydeco (ivacaftor) for people with cystic fibrosis (CF). (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - August 3, 2014 Category: Pharmaceuticals Source Type: news

Cystic fibrosis unit for children opens at University Hospital Galway
New unit includes four examination rooms, treatment room and gym for assessment and physiotherapy, along with support services (Source: The Irish Times - Health)
Source: The Irish Times - Health - July 29, 2014 Category: Consumer Health News Source Type: news

Cystic Fibrosis Drug Combo May Be Less Effective Than Hoped
Title: Cystic Fibrosis Drug Combo May Be Less Effective Than HopedCategory: Health NewsCreated: 7/23/2014 2:36:00 PMLast Editorial Review: 7/24/2014 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - July 24, 2014 Category: Respiratory Medicine Source Type: news

Cystic Fibrosis Drug Combo May Be Less Effective Than Hoped
One medication seems to partly counteract the other, suggests study on human cells (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - July 24, 2014 Category: Respiratory Medicine Authors: webmaster at doctorslounge.com Tags: Pharmacy, Pulmonology, Research, News, Source Type: news

Cystic Fibrosis Drug Combo May Be Less Effective Than Hoped
One medication seems to partly counteract the other, suggests study on human cells (Source: WebMD Health)
Source: WebMD Health - July 23, 2014 Category: Consumer Health News Source Type: news

Unsuspected characteristics of new cystic fibrosis drugs found, offering potential paths to more effective therapies
A large phase 3 clinical trial for cystic fibrosis patients has concluded, showing that a combination of two new cystic fibrosis drugs modestly improved lung function and offered better health outcomes for some patients. Now, scientists have shown that one of these drugs counteracts the intended beneficial molecular effect of the other. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 23, 2014 Category: Science Source Type: news

Cystic Fibrosis Drug Combo May Be Less Effective Than Hoped
One medication seems to partly counteract the other, suggests study on human cells Source: HealthDay Related MedlinePlus Pages: Cystic Fibrosis, Medicines (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 23, 2014 Category: Consumer Health News Source Type: news

Why it's so hard to develop a drug for cystic fibrosis
Two new studies suggest novel therapies can interfere with each other (Source: ScienceNOW)
Source: ScienceNOW - July 23, 2014 Category: Science Source Type: news

Dead man walking: ‘Living with cystic fibrosis - I wasn’t expected to make it past 17’
TIM WOTTON is active, fit, happily married and a proud father - yet it's a miracle that he has reached the age of 43. Here he talks to Express.co.uk about life with the genetic disease cystic fibrosis. (Source: Daily Express - Health)
Source: Daily Express - Health - July 23, 2014 Category: Consumer Health News Source Type: news

UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies
(University of North Carolina Health Care) Last month, the pharmaceutical company Vertex released results from a large phase 3 clinical trial for cystic fibrosis patients, showing that a combination of two new cystic fibrosis drugs modestly improved lung function and offered better health outcomes for some patients. Now, scientists at the University of North Carolina School of Medicine and the University of North Carolina Marsico Lung Institute have shown that one of these drugs counteracts the intended beneficial molecular effect of the other. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 23, 2014 Category: Global & Universal Source Type: news

Costly Drug Is Denied; Medicaid Takes Heat
Vertex Pharmaceuticals' $300,000-a-year cystic-fibrosis drug has sparked a battle in Arkansas, illustrating the dilemma faced by cash-strapped government insurance programs. (Source: WSJ.com: Health)
Source: WSJ.com: Health - July 17, 2014 Category: Pharmaceuticals Tags: PAID Source Type: news

Cystic Fibrosis Market Sales to Grow $5.3 Billion with 28.96% CAGR to...
ReportsnReports.com adds “OpportunityAnalyzer: Cystic Fibrosis - Opportunity Analysis and Forecasts to 2018 – Event-Driven Update” to its store. The majority of Cystic Fibrosis sales will come from...(PRWeb July 16, 2014)Read the full story at http://www.prweb.com/releases/cystic-fibrosis-market/analysis-forecasts-2018/prweb12022260.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - July 17, 2014 Category: Pharmaceuticals Source Type: news

Costly Drug Is Denied, Medicaid Takes Heat
Vertex Pharmaceuticals' $300,000-a-year cystic-fibrosis drug has sparked a battle in Arkansas, illustrating the dilemma faced by cash-strapped government insurance programs. (Source: WSJ.com: Health)
Source: WSJ.com: Health - July 17, 2014 Category: Pharmaceuticals Tags: PAID Source Type: news

acapella® choice Helps Cystic Fibrosis Patients
acapella® choice, the stand-alone oscillating Positive Expiratory Pressure (PEP) therapy device, from Smiths Medical, is effective in managing excessive secretion generation and conditions associated with cystic fibrosis. (Source: Pharmacy Europe)
Source: Pharmacy Europe - July 14, 2014 Category: Drugs & Pharmacology Authors: ebercott Tags: *** Editor's Pick Medical Devices Respiratory Latest News Source Type: news

Fiance of cystic fibrosis patient who died urges people to join donor register
EXCLUSIVE: Josh Nelli, from Kesgrave in Suffolk, is today urging people to sign the Organ Donation Register after his partner of five years Kerry Thorpe died waiting for a double lung transplant at the age of 23. (Source: the Mail online | Health)
Source: the Mail online | Health - July 13, 2014 Category: Consumer Health News Source Type: news

Proud parents urge HSE to fund genetic screening of embryos
Pre-implantation test helped couple who carry Cystic fibrosis gene have healthy baby (Source: The Irish Times - Health)
Source: The Irish Times - Health - July 12, 2014 Category: Consumer Health News Source Type: news

How did a work experience girl make a major cystic fibrosis breakthrough?
Jo Armstead, a 21-year-old medical student, was given a work experience task she thought she could simply 'Google'. Here she explains how instead, it became an 11-month project that led to a significant breakthrough (Source: Telegraph Health)
Source: Telegraph Health - July 8, 2014 Category: Consumer Health News Tags: cystic fibrosis work experience jo armstead research breakthrough student medicine doctor Source Type: news

Birth of first baby screened for Cystic Fibrosis a ‘milestone’
Centre screened embryos for genetic conditions prior to implantation (Source: The Irish Times - Health)
Source: The Irish Times - Health - July 5, 2014 Category: Consumer Health News Source Type: news

PTC Therapeutics begins Phase III trial of Translarna to treat nonsense mutation cystic fibrosis
US-based biopharmaceutical firm PTC Therapeutics has started a global confirmatory Phase III clinical trial of Translarna (ataluren), an investigational new drug, in patients with nonsense mutation cystic fibrosis (nmCF). (Source: Drug Development Technology)
Source: Drug Development Technology - June 30, 2014 Category: Pharmaceuticals Source Type: news

Vertex Receives European CHMP Positive Opinion for KALYDECO(TM) (ivacaftor) in Eight Non-G551D Gating Mutations
In Europe, approximately 250 people ages 6 and older have one of 8 additional gating mutations KALYDECO is the first medicine to treat the underlying cause of CF in people with non-G551D gating mutations EYSINS, Switzerland--(Healthcare Sales & Marke... Biopharmaceuticals, RegulatoryVertex Pharmaceuticals, KALYDECO, ivacaftor, cystic fibrosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 27, 2014 Category: Pharmaceuticals Source Type: news

Jo Armstead on work experience at Wythenshawe Hospital, makes major cystic fibrosis breakthrough
Newcastle University student Jo Armstead, 21, (pictured) discovered that half of adults who suffer from the rare genetic disorder are infected with a common fungus while working at Wythenshawe Hospital in Manchester. (Source: the Mail online | Health)
Source: the Mail online | Health - June 26, 2014 Category: Consumer Health News Source Type: news

Vertex's Cystic-Fibrosis Treatment Shows Promise
Vertex Pharmaceuticals said it would seek regulatory approval later this year for an experimental cystic-fibrosis drug that helped produce a statistically significant improvement in patients' lung function. (Source: WSJ.com: Health)
Source: WSJ.com: Health - June 25, 2014 Category: Pharmaceuticals Tags: PAID Source Type: news

Should Reporters Have Agreed To The Vertex Embargo?
This morning at 7 a.m., Vertex Pharmaceuticals released big news: adding a new drug, lumacaftor, to its existing cystic fibrosis drug Kalydeco increased by an order of magnitude the number of patients the medicine can help -- although the combo is still not as effective as Kalydeco is in patients who have a particular, rare mutation. I had a story up at 7:05. Adam Feuerstein at TheStreet.com, Andrew Pollack at the New York Times, and Meg Tirrell at CNBC all published their stories at the same time. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 24, 2014 Category: Pharmaceuticals Authors: Matthew Herper Source Type: news

Vertex cystic fibrosis combo succeeds in key late-stage trials
(Reuters) - A combination of Vertex Pharmaceuticals Inc's VRTX.O cystic fibrosis drugs succeeded in improving lung function in a pair of closely watched late-stage trials, likely offering a potential new treatment for thousands more patients with the rare lung disease and sending Vertex shares soaring. (Source: Reuters: Health)
Source: Reuters: Health - June 24, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Vertex Soars 40% On New Cystic Fibrosis Drug Combo Results
Tuesday brought good news for those suffering with cystic fibrosis -- as well as Vertex Pharmaceuticals investors. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 24, 2014 Category: Pharmaceuticals Authors: Brian Solomon Source Type: news

In A Victory For Gene Research, Vertex Drug Combo Clears Lungs Clogged By Cystic Fibrosis
In the war against genetic disease, scientists just gained some important ground. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 24, 2014 Category: Pharmaceuticals Authors: Matthew Herper Source Type: news

Vertex’s 2-Drug Cystic Fibrosis Pill Shows Promise
A combination of its drugs slightly improved lung function of patients with the genetic disease in trials closely watched by Wall Street. (Source: NYT Health)
Source: NYT Health - June 24, 2014 Category: Consumer Health News Authors: By ANDREW POLLACK Tags: Cystic Fibrosis Drugs (Pharmaceuticals) Medicine and Health Source Type: news

Aradigm doses first patient in Phase III trial of Pulmaquin
US-based pharmaceutical firm Aradigm has started dosing patients in the ORBIT-4 Phase III clinical trial of its proprietary formulation of inhaled ciprofloxacin (Pulmaquin) to treat non-cystic fibrosis bronchiectasis (non-CF BE). (Source: Drug Development Technology)
Source: Drug Development Technology - June 23, 2014 Category: Pharmaceuticals Source Type: news

New hope for cystic fibrosis... in medication derived from Norwegian seaweed
The active ingredient in the new treatment is a highly purified type of alginate, a carbohydrate found in the walls of sea plants. (Source: the Mail online | Health)
Source: the Mail online | Health - June 14, 2014 Category: Consumer Health News Source Type: news

Cannabis and sunshine may damage sperm quality
ConclusionThis study has found that the shape of sperm is less likely to be normal when samples are provided in summer and if cannabis has been consumed in the previous three months. It has also found that normal-shaped sperm are more likely to be produced after six days of abstinence. It did not find any other links between lifestyle factors and sperm shape.The results of this study alone do not show that lifestyle factors other than cannabis are harmless. Male fertility is not just determined by the shape of the sperm; it is also dependent on the concentration, motility and viability of the sperm, as well as the quality ...
Source: NHS News Feed - June 5, 2014 Category: Consumer Health News Tags: Genetics/stem cells Lifestyle/exercise Cancer Source Type: news

Increased mucins pinned to worsening cystic fibrosis symptoms
The first quantitative evidence that mucins – the protein framework of mucus – are significantly increased in cystic fibrosis patients, and play a major role in failing lung function, has been presented by researchers. The research shows that a three-fold increase of mucins dramatically increases the water-draining power of the mucus layer. This hinders mucus clearance in the CF lung, resulting in infection, inflammation, and ultimately lung failure. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 3, 2014 Category: Science Source Type: news

Cystic fibrosis and diabetes link explained
(Lund University) Many people with cystic fibrosis develop diabetes. The reasons for this have been largely unknown, but now researchers at Lund University in Sweden and Karolinska institutet have identified a molecular mechanism that contributes to the raised diabetes risk. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 2, 2014 Category: Global & Universal Source Type: news

JCI online ahead of print table of contents for June 2, 2014
(Journal of Clinical Investigation) This release contains summaries, links to PDFs, and contact information for the following newsworthy papers published online, June 2, 2014 in the JCI: 'Mucin concentration contributes to a sticky situation in cystic fibrosis,' 'Engineered aptimer targets malignant and tumor-associated T cells,' 'NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB,' 'Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease,' 'Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation,' and more. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2014 Category: Cancer & Oncology Source Type: news