Spraying new genes into your lungs could ease misery of cystic fibrosis 
For Oli Dillon, 17, from Kent, an effective therapy for cystic fibrosis can't come soon enough. (Source: the Mail online | Health)
Source: the Mail online | Health - November 9, 2015 Category: Consumer Health News Source Type: news

First steps towards new therapy for diseases caused by defective anion transport
Research by a team at the University of Bristol has taken the first steps towards new treatments for inherited diseases such as cystic fibrosis; one form of Bartter’s syndrome (severe salt loss from the kidney); and two forms of myotonia (muscle stiffness), which are linked to defective movement of anions, such as chloride, across cell membranes. (Source: University of Bristol news)
Source: University of Bristol news - November 5, 2015 Category: Universities & Medical Training Tags: Health, Research; Faculty of Biomedical Sciences, School of Physiology and Pharmacology, Faculty of Science, School of Chemistry, Faculty of Science, Faculty of Biomedical Sciences, Institutes, Elizabeth Blackwell; Press Release Source Type: news

Charlotte, 21, reveals her gratitude for a organ donor gift beyond price
Charlotte Davies, now 21, from Kent, was born with cystic fibrosis, a genetic condition where the lungs and digestive system become clogged with thick, sticky mucus. (Source: the Mail online | Health)
Source: the Mail online | Health - November 2, 2015 Category: Consumer Health News Source Type: news

Husband of mother dying from cystic fibrosis writes letter pleading for more organ donors
Ashley Harris Moore is waiting for a double lung transplant after suffering all her life from cystic fibrosis (Source: Telegraph Health)
Source: Telegraph Health - October 29, 2015 Category: Consumer Health News Tags: cystic fibrosis alastair transplant lung donor donation organ lungs husband ashley harris moore Source Type: news

Vertex Revenue Soars on Growth for Cystic Fibrosis Drugs
Vertex Pharmaceuticals said third-quarter revenue soared 73% as the Boston biotechnology company posted better-than-expected sales of cystic fibrosis drugs Kalydeco and recently launched Orkambi. (Source: WSJ.com: Health)
Source: WSJ.com: Health - October 28, 2015 Category: Pharmaceuticals Tags: PAID Source Type: news

Who Owns Your Genes?
By Diana Brazzell, Co-Founder & Executive Editor, Footnote This post was originally published on Footnote, a website that brings academic research and ideas to a broader audience. New forms of genetic testing can predict whether a couple will have a child with cystic fibrosis, guide doctors in selecting the most effective chemotherapy for a breast cancer patient, and help researchers unlock the causes of Alzheimer's disease. While these advances have the potential to save lives and transform medical research, they also raise serious ethical questions about the balance between privacy and health - questions that scienti...
Source: Science - The Huffington Post - October 27, 2015 Category: Science Source Type: news

23andMe launches new consumer test service to check for genetic disorders
NEW YORK/CHICAGO (Reuters) - Genetics company 23andMe announced the launch of a new consumer genetic test service on Wednesday that will show whether an individual carries genes associated with 36 different disorders, such as cystic fibrosis. (Source: Reuters: Health)
Source: Reuters: Health - October 21, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

Advanced Inhalation Therapies reveals finances ahead of IPO
Advanced Inhalation revealed its finances for the past 2 years as it plans for its oncoming $36 million initial public offering to raise funds for its device designed to treat severe respiratory infections and lung diseases using a high dose of nitric oxide. Advanced Inhalation reported losses of $4.6 million, or 41¢ per share for 2014. That’s up nearly 200% from 2013, when the company reported $1.6 million losses, or 14¢ per share. The last 6 months have been kinder to the Rehovot, Israel-based company, which reported losses of $2 million, or 20¢ per share this year, compared to $3.2 million and ...
Source: Mass Device - October 19, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Business/Financial News Drug Pumps Respiratory Advanced Inhalation Therapies Source Type: news

Corbus begins dosing in Phase II Resunab trial to treat cystic fibrosis
US-based drug development firm Corbus Pharmaceuticals (CRBP) has started dosing in the Phase II clinical trial of its investigational new oral drug Resunab to treat cystic fibrosis (CF). (Source: Drug Development Technology)
Source: Drug Development Technology - October 15, 2015 Category: Pharmaceuticals Source Type: news

25-year-old Georgina Compton with cystic fibrosis gets much needed lung transplant
Georgina Compton, 25, from Surrey, has battled the genetic condition cystic fibrosis since birth. But being just 4'11" tall, her body was too small for most adult organs. (Source: the Mail online | Health)
Source: the Mail online | Health - October 13, 2015 Category: Consumer Health News Source Type: news

Women with cystic fibrosis bravely bare their scars for Salty Girls book
Ian Pettigrew, a 46-year-old photographer from Ontario, Canada, who is also battling cystic fibrosis, photographed 77 adult women who suffer from the disease for his book Salty Girls. (Source: the Mail online | Health)
Source: the Mail online | Health - October 13, 2015 Category: Consumer Health News Source Type: news

The Man Who Grew Eyes
The train line from mainland Kobe is a marvel of urban transportation. Opened in 1981, Japan’s first driverless, fully automated train pulls out of Sannomiya station, guided smoothly along elevated tracks that stand precariously over the bustling city streets below, across the bay to the Port Island. The island, and much of the city, was razed to the ground in the Great Hanshin Earthquake of 1995 – which killed more than 5,000 people and destroyed more than 100,000 of Kobe’s buildings – and built anew in subsequent years. As the train proceeds, the landscape fills with skyscrapers. The Rokkō mounta...
Source: Healthy Living - The Huffington Post - October 11, 2015 Category: Consumer Health News Source Type: news

The Man Who Grew Eyes
The train line from mainland Kobe is a marvel of urban transportation. Opened in 1981, Japan’s first driverless, fully automated train pulls out of Sannomiya station, guided smoothly along elevated tracks that stand precariously over the bustling city streets below, across the bay to the Port Island. The island, and much of the city, was razed to the ground in the Great Hanshin Earthquake of 1995 – which killed more than 5,000 people and destroyed more than 100,000 of Kobe’s buildings – and built anew in subsequent years. As the train proceeds, the landscape fills with skyscrapers. The Rokkō mounta...
Source: Science - The Huffington Post - October 11, 2015 Category: Science Source Type: news

Anthera begins Sollpura Phase III trial to treat EPI in patients with cystic fibrosis
Anthera Pharmaceuticals has started a Phase III trial (Solution) of Sollpura (liprotamase) to treat patients with exocrine pancreatic insufficiency (EPI) due to cystic fibrosis (CF). (Source: Drug Development Technology)
Source: Drug Development Technology - October 4, 2015 Category: Pharmaceuticals Source Type: news

Bailey Anne Vincent diagnosed with cystic fibrosis reveals devastation
Bailey Anne Vincent, a beauty blogger, was diagnosed with the life-threatening disease after she had her first baby, but was just told by doctors that they now don't know exactly what she has. (Source: the Mail online | Health)
Source: the Mail online | Health - September 30, 2015 Category: Consumer Health News Source Type: news

Five genetic regions implicated in cystic fibrosis severity
If you have two faulty copies of the CFTR gene, you will have cystic fibrosis. But the severity of your disease will depend partly on many other genes. Now, researchers report that five regions of the human genome are home to the genetic variations that play major roles in disease severity. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 29, 2015 Category: Science Source Type: news

Let charities take a leading role in discovering antibiotics | the big issue
There is a thriving charity sector developing new drugs – let them work on antibiotic resistanceSeventy years ago Sir Alexander Fleming, the discoverer of penicillin, in his Nobel prize acceptance speech warned that inappropriate use of antibiotics would give rise to resistance (“Time for world to act on antibiotic resistance”, leader, Comment). Fleming’s prediction has come to pass and antibiotic resistance is now threatening modern medicine.Routine procedures including heart bypass surgery, hip and knee replacements, cancer treatments, childbirth, trauma surgery and intensive care treatments all d...
Source: Guardian Unlimited Science - September 26, 2015 Category: Science Authors: Guardian Staff Tags: Antibiotics Medical research Society Science Source Type: news

CHMP Backs Combo Drug Orkambi for Cystic FibrosisCHMP Backs Combo Drug Orkambi for Cystic Fibrosis
Orkambi combines lumacaftor and ivacaftor and is indicated for patients with CF aged 12 years and older who are homozygous for the F508del mutation in the CFTR gene. International Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 25, 2015 Category: Consumer Health News Tags: Pulmonary Medicine News Alert Source Type: news

Terminally ill gymnast Sonny Lang has the 'heart and lungs of an 80-year-old'
Sonny Lang, 22, from Tadcaster, North Yorkshire, has cystic fibrosis, but has been told her body is too weak for another heart and lung transplant, so her prognosis is terminal. (Source: the Mail online | Health)
Source: the Mail online | Health - September 23, 2015 Category: Consumer Health News Source Type: news

Corbus enrols first patient in Phase II trial of Resunab to treat cystic fibrosis in adults
US-based Corbus Pharmaceuticals Holdings has started patient enrolment in the Phase II clinical trial of its investigational new drug Resunab to treat adult patients with cystic fibrosis (CF). (Source: Drug Development Technology)
Source: Drug Development Technology - September 21, 2015 Category: Pharmaceuticals Source Type: news

New nebulizer set to replace the need for jabs
A revolutionary nebulizer could one day deliver life-saving cancer drugs and vaccines traditionally given by injection. Cheap, light-weight and portable, the advanced nebuliser delivers precise drug doses to patients with life-threatening or debilitating lung conditions including cancer, tuberculosis, asthma and cystic fibrosis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 18, 2015 Category: Science Source Type: news

Bobby Donovan’s double lung transplant journey
Twenty-two-year-old Bobby Donovan was diagnosed with Cystic Fibrosis (CF) at 4 months old. He was relatively healthy for someone with CF. However, in November of 2008 his health began to deteriorate. Every three months or so, he was admitted to Boston Children’s Hospital for two to four weeks at a time. In April of 2014, with his lungs not expected to last the year, Bobby received the double lung transplant, which not only saved, but transformed his life. One year following surgery, he shares his remarkable story. Learn more about the Boston Children’s Lung Transplant Program. The post ...
Source: Thrive, Children's Hospital Boston - September 10, 2015 Category: Pediatrics Authors: Emily Williams Tags: Diseases & conditions Our patients’ stories cystic fibrosis Cystic Fibrosis Center double lung transplant Lung Transplant Program lungs Pediatric Transplant Center (PTC) Source Type: news

Sharp Edge Labs and Creagen Biosciences Enter Drug Discovery...
Agreement could bring new treatments for diseases including Parkinson’s, Alzheimer’s and Cystic Fibrosis.(PRWeb September 09, 2015)Read the full story at http://www.prweb.com/releases/2015/09/prweb12948107.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - September 10, 2015 Category: Pharmaceuticals Source Type: news

Queen's leads €50 million program to develop new antibiotics for cystic fibrosis and bronchiectasis
(Queen's University Belfast) The iABC (inhaled Antibiotics in Bronchiectasis and Cystic Fibrosis) consortium, which is made up of world-leading lung specialists from across Europe, will develop new 'inhaled antibiotics' to manage chronic lung infection, the main cause of disease and death in patients with cystic fibrosis and bronchiectasis. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 7, 2015 Category: Infectious Diseases Source Type: news

Intussusception By The Numbers
Discussion Intussusception occurs when one segment of the gastrointestinal tract telescopes into an adjacent segment. The outer receiving segment of bowel is known as the intussuscipiens and the inner inverting segment is known as the intussusceptum. It occurs most often in children between 2 months to 5 years, with a peak incidence between 4-10 months. Males are more often affected than females by 3:2. It also occurs more often after abdominal operations particularly in the first 2 weeks. It is the second most common acute abdominal emergency in children after appendicitis. In adults ~80% have an underlying cause or lead ...
Source: PediatricEducation.org - September 7, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

New research discovers immune system protein can fix cystic fibrosis cells
(Faculty of 1000) Scientific experiments examining what happens to the faulty channel protein that causes cystic fibrosis during inflammation have yielded unexpected and exciting results. The study, conducted by Sara Bitam and her colleagues at INSERM in France, has just passed peer review on open science publishing platform F1000Research. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 2, 2015 Category: Global & Universal Source Type: news

Medical News Today: Cystic fibrosis: yeast study may address root cause
Cystic fibrosis results from a mutation that stops ions moving in and out of cells. Now, a study shows how a small molecule restored ion channel function in deficient yeast cells. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 29, 2015 Category: Consumer Health News Tags: Cystic Fibrosis Source Type: news

Hugh Jackman Surprises Fan With Cystic Fibrosis. Cue The 'Aww'
This is basically all the proof you need that Wolverine is the best of the X-Men.  A 9-year-old boy named Domenic, who has cystic fibrosis, is a huge superhero fan -- especially of Wolverine, according to a video uploaded to YouTube. With the help of the Make-A-Wish Foundation the boy recently had the chance to sit down with Australian radio hosts Kyle And Jackie O on their show and call the mutant himself, Hugh Jackman.  While the boy thought he was just going to talk to the actor over the phone, Jackman burst into the room and surprised Domenic, even growling in character. The incident was caught...
Source: Healthy Living - The Huffington Post - August 28, 2015 Category: Consumer Health News Source Type: news

Tackling the root cause of cystic fibrosis
(American Chemical Society) Treatments for cystic fibrosis (CF) have added years to the lives of thousands of Americans. But they can be difficult to administer, and most don't fix the underlying cause. Scientists have now found that a small molecule, when tested in yeast, can substitute for a protein and restore a key cellular function related to those missing in people with CF and similar conditions. Their report appears in the Journal of the American Chemical Society. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 26, 2015 Category: Biology Source Type: news

5 things to know about teens and depression
How does depression impact children and teens?   Depression impacts many youth and families across the U.S. Up to 28% of young people experience an episode of major depression by age 19 with an average onset age of 13 years old. However, only 38% of teens experiencing depression receive treatment. Raising awareness is a key step to addressing depression. Depression is treatable, and early detection and treatment are effective. With increased awareness and early intervention efforts, both teens and adults can learn to identify the signs of depression and get help sooner. Left untreated, depression can lead to deterior...
Source: Thrive, Children's Hospital Boston - August 24, 2015 Category: Pediatrics Authors: Karen Capraro Tags: Diseases & conditions parenting Depression grief Source Type: news

'Clue' to cystic fibrosis infection
Scientists have shed light on why a common and sometimes fatal lung infection in people who have cystic fibrosis can be so hard to treat. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - August 20, 2015 Category: Consumer Health News Source Type: news

Bacteria evolve differences within the lungs of patients with cystic fibrosis
Treatments for the same opportunistic bacteria found in cystic fibrosis patients can work in one area in the lung and be less effective in others. The reason, researchers report, is that bacteria become isolated from one another and evolve region-specific traits. Researchers saw differences in bacterial nutritional requirements, host defenses, and antibiotic resistance. The findings suggest that other chronic infections may yield similar bacterial diversity. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 20, 2015 Category: Science Source Type: news

In the shadow of Vertex, small cystic fibrosis-focused biotechs thrive
The undisputed leader in the field of drugs to treat cystic fibrosis is Boston’s Vertex Pharmaceuticals, but that company’s success is spurring some smaller, recently-public biotechs to focus on drugs to treat the inherited, fatal disease. Corbus Pharmaceuticals (Nasdaq: CRBP) in Norwood, which just started trading on the Nasdaq exchange in April, has attracted attention for its potential drug, Resunab, which is about to begin mid-stage trials to treat inflammation associated with CF. But in… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - August 17, 2015 Category: American Health Authors: Don Seiffert Source Type: news

Changing the Unchangeable
We are each confronted with components of our life and ourselves that we are unable to alter. As much as we strive to cling to a life created of our mind's idea of perfection, it is merely impossible. There are some elements of life that are simply out of our control: unable to be changed. But within each unchangeable circumstance there is something most beautiful. The most beautiful thing? We do have control and we can change it. We each control how we allow these unchangeable and inalterable factors to impact us, shape us, mold us, and motivate us. We ourselves are far greater than any tragedy, diagnosis, despair, or st...
Source: Healthy Living - The Huffington Post - August 13, 2015 Category: Consumer Health News Source Type: news

Cystic fibrosis suffering teen fulfils the last item on her bucket list after death
Harriet Sheehan, 15, of Cumbria, suffered from cystic fibrosis and died in February. Before her death she donated her eyes and her parents recently learned they saved a man's sight. (Source: the Mail online | Health)
Source: the Mail online | Health - August 11, 2015 Category: Consumer Health News Source Type: news

Nanoparticles Used to Breach Mucus Barrier in Lungs - 8/3/15
Researchers at the Johns Hopkins University School of Medicine, Johns Hopkins University Department of Chemical and Biomolecular Engineering, and Federal University of Rio de Janeiro in Brazil have designed a DNA-loaded nanoparticle that can pass through the mucus barrier covering conducting airways of lung tissue — proving the concept, they say, that therapeutic genes may one day be delivered directly to the lungs to the levels sufficient to treat cystic fibrosis (CF), chronic obstructive pulmonary disease, asthma and other life-threatening lung diseases. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - August 3, 2015 Category: Research Source Type: news

Vertex Revenue Rises 20%
Vertex Pharmaceuticals Inc. said its second-quarter revenue rose 20% on strong sales of Kalydeco that led the biotechnology company to raise its 2015 sales guidance for the cystic-fibrosis drug. (Source: WSJ.com: Health)
Source: WSJ.com: Health - July 29, 2015 Category: Pharmaceuticals Tags: PAID Source Type: news

Medical News Today: Cystic fibrosis: new understanding of infections
Lab work on the microorganisms found in sputum unveils secrets of their 'aerobic and anaerobic lifestyles' in cystic fibrosis to help with future studies and clinical testing. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 29, 2015 Category: Consumer Health News Tags: Cystic Fibrosis Source Type: news

Will The High Cost Of Vertex's New Cystic Fibrosis Drug Push The U.S. To European Style Pricing?
But when true breakthroughs occur, it can be years before a competitive therapy emerges. Thus, we have the current situation of higher prices in the U.S. It is hard to envision this remaining the status quo over the next five years. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - July 22, 2015 Category: Pharmaceuticals Authors: John LaMattina Source Type: news

Quicker tests for lung infections
Scientists at Cardiff University are using DNA testing by robots to help identify infections in cystic fibrosis patients more quickly and accurately. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - July 21, 2015 Category: Consumer Health News Source Type: news

What It Really Feels Like To Be In A Coma
Claire Wineland is a 17-year-old Los Angeles teen living with cystic fibrosis, a serious genetic condition that causes fluid buildup in the lungs. After spending two weeks in a medically-induced coma, she decided to tell the world exactly what it was like. Wineland explained the experience in a video for her YouTube channel The Clairity Project, a platform where she chronicles her experience of living with cystic fibrosis in humorous, upbeat and compelling videos.   In the video "What It's Like To Be In A Coma," Wineland described feeling like she was in Alaska -- only to find out that's when doctors we...
Source: Science - The Huffington Post - July 20, 2015 Category: Science Source Type: news

Smithfield and BBQ Pitmaster Moe Cason "Grill for a Cure" to Benefit Cystic Fibrosis Foundation
(Source: Medical News (via PRIMEZONE))
Source: Medical News (via PRIMEZONE) - July 18, 2015 Category: Pharmaceuticals Source Type: news

Cystic Fibrosis patients get new chance at life
It's being called a game-changer for people with one deadly genetic disease. A new drug is now on the market giving hope to thousands diagnosed with cystic fibrosis. We introduce you to a young Louisiana girl getting a chance at a longer life and tell you how close researchers may be to curing the deadly disease. (Source: WDSU.com - Health)
Source: WDSU.com - Health - July 16, 2015 Category: Consumer Health News Source Type: news

Teen Explains What Life is Like in a Coma
Teen with cystic fibrosis describes life in a coma. (Source: ABC News: Health)
Source: ABC News: Health - July 16, 2015 Category: Consumer Health News Tags: Health Source Type: news

Scientists grow 'mini bile ducts' to help discovery of new drugs
An experimental cystic fibrosis drug has been shown to prevent the disease’s damage to the liver, thanks to a world-first where scientists grew mini bile ducts in the lab.  (Source: Medical Research Council General News)
Source: Medical Research Council General News - July 14, 2015 Category: Research Source Type: news

Stem cells might heal damaged lungs
Collectively, such diseases of the airways as emphysema, bronchitis, asthma and cystic fibrosis are the second leading cause of death worldwide. More than 35 million Americans alone suffer from chronic respiratory disease. Scientists have now proposed a new direction that could, in the future, lead to the development of a method for alleviating some of their suffering. The study's findings show how it might be possible to use embryonic stem cells to repair damaged lung tissue. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 14, 2015 Category: Science Source Type: news

Scientists create 'mini bile ducts' to discover new drugs that could prevent the need for liver transplantation
An experimental cystic fibrosis drug has been shown to prevent the disease’s damage to the liver, thanks to a world-first where scientists grew mini bile ducts in the lab.  (Source: Medical Research Council General News)
Source: Medical Research Council General News - July 13, 2015 Category: Research Source Type: news

How family friend recognised the signs of cystic fibrosis
Cystic fibrosis sufferer Charlie York, 11, from North Yorkshire, has survived major surgery to replace his failing lungs. He is pictured with his mother Sasha. (Source: the Mail online | Health)
Source: the Mail online | Health - July 13, 2015 Category: Consumer Health News Source Type: news

Setting the Scene of Life
"All the world's a stage, And all the men and women are merely players." - Shakespeare Time: Present Setting: An operating room, doctor's office Characters: Ashley (me), Mark, Radiologist, Pulmonologist, Nurses, Receptionists Call it a coping mechanism, a way for me to deal with my reality, or simply a means to save myself from exposing a deep set pain and fear by being solely focused on the present scene. Doing all in hopes of avoiding any thoughts of the next act. Of course, the next act is filled with incredible opportunity and possibility, but it's also filled with pages of uncertainty. There's an unsettle...
Source: Healthy Living - The Huffington Post - July 13, 2015 Category: Consumer Health News Source Type: news