Inhaling Hypertonic Saline May Aid Infants With Cystic Fibrosis
THURSDAY, Dec. 13, 2018 -- In infants with cystic fibrosis (CF), preventive inhalation with hypertonic saline (HS) during the first months of life is safe and well tolerated and results in clinical improvements, according to a study recently... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 13, 2018 Category: Pharmaceuticals Source Type: news

'Our Christmas miracle is happening': 17-year-old with cystic fibrosis awakes from two-week coma
Christina VanDerVelden, 17, of Jacksonville, Florida, slipped into a week-long coma after her healthy rapidly declined. The cystic fibrosis sufferer now needs a double lung transplant to survive. (Source: the Mail online | Health)
Source: the Mail online | Health - December 12, 2018 Category: Consumer Health News Source Type: news

Blood test could lead to cystic fibrosis treatment tailored to each patient
(Ann& Robert H. Lurie Children's Hospital of Chicago) Researchers at Stanley Manne Children's Research Institute at Ann& Robert H. Lurie Children's Hospital of Chicago, and colleagues, used a blood test and microarray technology to identify distinct molecular signatures in children with cystic fibrosis. These patterns of gene expression ultimately could help predict disease severity and treatment response, and lead to therapies tailored to each patient's precise biology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 12, 2018 Category: International Medicine & Public Health Source Type: news

Calling the Shots?
The USA has the highest drug costs in the world, and they are increasing at the fastest rate too. With one in five Americans saying they have been forced to leave a prescription unfilled due to high costs, the situation is clearly unsustainable.Payers and pharmacy benefit managers (PBMs), themselves facing increased criticism for blocking access to important medicines, are taking action by demanding that pharma companies justify the cost – and value – of their new medicines.“There is a point where a government, an employer or a healthcare plan has a finite amount of resources to spend,” says Brian H...
Source: EyeForPharma - December 10, 2018 Category: Pharmaceuticals Authors: Katie Osborne Source Type: news

Hypertonic-Saline Inhalation Boosts Lung Function in Infants With Cystic Fibrosis Hypertonic-Saline Inhalation Boosts Lung Function in Infants With Cystic Fibrosis
Inhalation of hypertonic saline improves lung function and growth in infants with cystic fibrosis (CF), according to the results of the PRESIS randomized controlled trial.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - December 7, 2018 Category: Pathology Tags: Pulmonary Medicine News Source Type: news

Vast Therapeutics Announces Series A Funding
Partnership with Shionogi Ltd Includes Collaboration for Development of Proprietary Nitric Oxide Powder Technology for Antimicrobial Resistant Bacteria in Respiratory Applications DURHAM, N.C., Dec. 5, 2018 -- (Healthcare Sales & Marketing Network) -- ... Biopharmaceuticals, Venture Capital Vast Therapeutics, KNOW Bio, nitric oxide, cystic fibrosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 5, 2018 Category: Pharmaceuticals Source Type: news

How a Vanilla Ice song helped one P.E.I. couple 'savour each and every moment'
Sheldon O’Meara has lived with cystic fibrosis for as long as he can remember and has recently been relegated to a hospital bed at the Queen Elizabeth Hospital in Charlottetown. (Source: CBC | Health)
Source: CBC | Health - December 3, 2018 Category: Consumer Health News Tags: News/Canada/PEI Source Type: news

How Ice, Ice, Baby helped one P.E.I. couple 'savour each and every moment'
Sheldon O’Meara has lived with cystic fibrosis for as long as he can remember and has recently been relegated to a hospital bed at the Queen Elizabeth Hospital in Charlottetown. (Source: CBC | Health)
Source: CBC | Health - December 3, 2018 Category: Consumer Health News Tags: News/Canada/PEI Source Type: news

Medical News Today: Celiac disease may be treated with cystic fibrosis drugs
New research investigates the similarities between cystic fibrosis and celiac disease, suggesting that drugs for the former may also treat the latter. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 3, 2018 Category: Consumer Health News Tags: Food Intolerance Source Type: news

Vertex posts positive data from cystic fibrosis triple combo trials
Vertex Pharmaceuticals Inc said on Tuesday that its triple combination therapy showed significant improvement in lung function in patients of cystic fibrosis (CF) in two late-stage clinical studies, sending its shares up 5 percent. (Source: Reuters: Health)
Source: Reuters: Health - November 27, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Changes in total IgE levels predict pulmonary outcome in cystic fibrosis related allergic bronchopulmonary aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 23, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Positive microbiology findings in non-cystic fibrosis bronchiectasis and co-morbidities
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 23, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Delayed Diagnosis of Cystic Fibrosis in a 62 Year Old Female Leading to Bilateral Lung Transplant
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Cystic Fibrosis Transmembrane Conductance Regulator ∆F508 Heterozygosity: A Spectrum of Disease Burden
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

3D Printing and the Cystic Fibrosis Lung
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Does Improved Lung Health Change the Incidence of Cystic Fibrosis-Related Diabetes?
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

High Frequency of Atopy with Geographic Variation in Non-Cystic Fibrosis Bronchiectasis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 19, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Omalizumab Treatment in Patients with Cystic Fibrosis (CF) and Allergic Bronchopulmonary Aspergillosis (ABPA): a Case Series
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 16, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Mother of girl with cystic fibrosis is taking legal action against the NHS after it refused drug
Sarah Burgwin, of Totnes, Devon, said it was 'shameful' that six-year-old Katie Stafford was being denied access to Orkambi, which can improve lung function in sufferers of the disease. (Source: the Mail online | Health)
Source: the Mail online | Health - November 14, 2018 Category: Consumer Health News Source Type: news

Devon mother in fight with NHS for cystic fibrosis drug funding
Sarah Burgwin wants the NHS to pay for Orkambi to treat her six-year-old daughter's cystic fibrosis. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - November 14, 2018 Category: Consumer Health News Source Type: news

Moths and magnets could save lives
(Rice University) Rice University bioengineers have combined a virus that infects moths with magnetic nanoparticles to create a potential new therapy for inherited genetic diseases like muscular dystrophy, sickle cell, cystic fibrosis, spinal muscular atrophy and some forms of cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 13, 2018 Category: Cancer & Oncology Source Type: news

Researchers identify risk factors of advanced liver disease in cystic fibrosis patients
(Children's Hospital Colorado) Children's Hospital Colorado (Children's Colorado) pediatric gastroenterologist, Michael Narkewicz, MD, recently shared results of the Prospective Study of Ultrasound to Predict Hepatic Cirrhosis in Cystic Fibrosis (PUSH), which sought to determine if liver ultrasounds could identify children and adolescents with cystic fibrosis who are at greater risk of developing advanced liver disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 12, 2018 Category: International Medicine & Public Health Source Type: news

Father with cystic fibrosis finally gets lung transplant after three failed attempts
James Beeching, 34, has had the incurable genetic condition since he was two years old. Three lung transplants fell through before his surgery. He can finally walk his twins to school in Hastings. (Source: the Mail online | Health)
Source: the Mail online | Health - November 7, 2018 Category: Consumer Health News Source Type: news

Most patients with cystic fibrosis may receive insufficient antibiotics to fight lung infections
(Children's National Health System) The majority of patients with cystic fibrosis may not achieve blood concentrations of antibiotics sufficiently high enough to effectively fight bacteria responsible for pulmonary exacerbations, leading to worsening pulmonary function, indicates a study led by researchers at Children's National Health System. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 6, 2018 Category: International Medicine & Public Health Source Type: news

10x Genomics takes gene imaging and analysis tools to the big leagues
10x Genomics Growth: 2,044% Rank: 1 What it does: Sells gene imaging and analysis tools CEO: Serge Saxonov HQ: Pleasanton 2017 Employees: 246 2017 revenue: $71.18 million 2016 revenue: $27.48 million 2015 revenue: $3.32 million In April, scientists at MIT and Harvard’s joint Broad Institute for bi omedical and genomic research made a tiny discovery that could have big implications for patients who suffer from the lung infections and breathing difficulties typical of cystic fibrosis. “Using… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - October 31, 2018 Category: American Health Authors: Lauren Hepler Source Type: news

10x Genomics takes gene imaging and analysis tools to the big leagues
10x Genomics Growth: 2,044% Rank: 1 What it does: Sells gene imaging and analysis tools CEO: Serge Saxonov HQ: Pleasanton 2017 Employees: 246 2017 revenue: $71.18 million 2016 revenue: $27.48 million 2015 revenue: $3.32 million In April, scientists at MIT and Harvard’s joint Broad Institute for bi omedical and genomic research made a tiny discovery that could have big implications for patients who suffer from the lung infections and breathing difficulties typical of cystic fibrosis. “Using… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 31, 2018 Category: Biotechnology Authors: Lauren Hepler Source Type: news

Mucus, cough and chronic lung disease: New discoveries
(University of Gothenburg) As a cold ends, a severe mucus cough starts. Sound familiar? Two studies now give explanations: First, crucial mechanisms of the mucus in both diseased and healthy airways; second, what happens in such chronic lung diseases as cystic fibrosis and chronic obstructive pulmonary disease (COPD). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 24, 2018 Category: International Medicine & Public Health Source Type: news

UAB researchers leading way on drug regimen battling cystic fibrosis
A triple combination drug has been shown to be effective in improving lung function for the majority of patients with cystic fibrosis.   The new therapy can provide therapeutic benefits for 90 percent of all patients with the disease, according to findings published in the New England Journal of Medicine. Researchers from UAB report the medication, which combines an experimental compound known as VX-659 with two existing medicati ons, tezacaftor and ivacaftor, improved lung function by more than… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - October 19, 2018 Category: American Health Authors: Tyler Patchen Source Type: news

Triple Combo Regimens May Address Cause of Cystic Fibrosis
FRIDAY, Oct. 19, 2018 -- Triple therapy with VX-659 or VX-445 combined with tezacaftor-ivacaftor shows promise for the treatment of adult patients with cystic fibrosis who have mutations in the cystic fibrosis transmembrane conductance regulator... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 19, 2018 Category: Pharmaceuticals Source Type: news

3-Drug Therapy Might Be Cystic Fibrosis 'Breakthrough'
Title: 3-Drug Therapy Might Be Cystic Fibrosis 'Breakthrough'Category: Health NewsCreated: 10/18/2018 12:00:00 AMLast Editorial Review: 10/19/2018 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - October 19, 2018 Category: Respiratory Medicine Source Type: news

3-Drug Therapy Might Be Cystic Fibrosis Advance
In what researchers call “a breakthrough,” two clinical trials have found that two different three-drug treatment plans could help 90 percent of people with cystic fibrosis. “It’s not a cure,” said one of the lead researchers. “But it could be game-changing.” (Source: WebMD Health)
Source: WebMD Health - October 18, 2018 Category: Consumer Health News Source Type: news

3 - Drug Therapy Might Be Cystic Fibrosis ‘ Breakthrough ’
(Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - October 18, 2018 Category: Respiratory Medicine Tags: Family Medicine, Pharmacy, Pulmonology, Research, News, Source Type: news

' Major Breakthrough' in Cystic Fibrosis Treatment'Major Breakthrough' in Cystic Fibrosis Treatment
Adding a third drug to modulate the CFTR protein improved respiratory function and reduced sweat chloride concentrations in most patients with cystic fibrosis. Phase 3 trials are ongoing.Medscape Medical News (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - October 18, 2018 Category: Primary Care Tags: Pulmonary Medicine News Source Type: news

3-Drug Therapy Might Be Cystic Fibrosis'Breakthrough '
THURSDAY, Oct. 18, 2018 -- In what researchers are calling a " breakthrough, " two preliminary trials have found that either of two triple-drug regimens could potentially benefit 90 percent of people with cystic fibrosis. The trials were short-term,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 18, 2018 Category: General Medicine Source Type: news

A day in the life of a 10-year-old patient at Alder Hey
She has cystic fibrosis and shared a day in her life to show what it's like for her. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 14, 2018 Category: Consumer Health News Source Type: news

I'm Drowning
(MedPage Today) -- A researcher-patient's plea for broader inclusion in cystic fibrosis trials (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - October 11, 2018 Category: American Health Source Type: news

Scientists reveal new cystic fibrosis treatments work best in inflamed airways
(University of North Carolina Health Care) A new UNC School of Medicine study shows that two cystic fibrosis (CF) drugs aimed at correcting the defected CFTR protein seem to be more effective when a patient's airway is inflamed. This is the first study to evaluate the efficacy of these drugs under inflammatory conditions relevant to CF airways. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 11, 2018 Category: Biology Source Type: news

Carriers of cystic fibrosis may be at greater risk for allergic bronchopulmonary aspergillosis
Tue, 10/09/2018 - 11:45News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 9, 2018 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Cystic fibrosis sufferer lifts one million kilograms in 22 hours
Josh Llewellyn-Jones completes the "crazy" challenge to inspire others living with the disorder. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 1, 2018 Category: Consumer Health News Source Type: news

Interventions for the eradication of meticillinresistant Staphylococcus aureus (MRSA) in people with cystic fibrosis
This review concluded that whilst early eradication of respiratory MRSA in cystic fibrosis with oral trimethoprim and sulfamethoxazole combined with rifampicin is possible, the evidence is of low quality to justify use. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 28, 2018 Category: Consumer Health News Source Type: news

Real-life experience of Omalizumab in adult Cystic Fibrosis patients with allergic severe asthma and Allergic Bronchopulmonary Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - September 27, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Nontuberculous Mycobacteria in Cystic Fibrosis Nontuberculous Mycobacteria in Cystic Fibrosis
In this article, the diagnosis, treatment, and impact of nontuberculous mycobacteria infection among patients with cystic fibrosis is discussed.Seminars in Respiratory and Critical Care Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 20, 2018 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Insuring patient access and affordability for treatments for rare and ultra-rare diseases
(American College of Medical Genetics and Genomics) The last decade has seen tremendous progress in the development of new drugs for patients with genetic disorders, including Cystic Fibrosis, many lysosomal storage disorders (Gaucher disease, Fabry disease and others) and most recently, Duchenne Muscular Dystrophy and Spinal Muscular Atrophy (SMA). The American College of Medical Genetics and Genomics (ACMG) is concerned with the staggering projected cost of these new treatments. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 7, 2018 Category: International Medicine & Public Health Source Type: news

Claire Wineland, who chronicled cystic fibrosis, dies at 21
Claire Wineland used social media platforms to speak about the difficult details of her life and spread awareness about the disease (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - September 4, 2018 Category: Consumer Health News Source Type: news

Claire Wineland, inspirational speaker and social media star, dies one week after lung transplant
Cystic fibrosis did not define Claire Wineland. She did. (Source: CNN.com - Health)
Source: CNN.com - Health - September 4, 2018 Category: Consumer Health News Source Type: news

Claire Wineland: Cystic fibrosis activist dies at 21
Claire Wineland made a name for herself writing and speaking about her life with the disease. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - September 4, 2018 Category: Consumer Health News Source Type: news

A lung transplant gave her hope for a longer life; now her family prays for 'another miracle'
Claire Wineland, who has cystic fibrosis, needed a double-lung transplant to save her life. But she had a stroke and is now in a medically induced coma. (Source: CNN.com - Health)
Source: CNN.com - Health - August 29, 2018 Category: Consumer Health News Source Type: news

Cystic fibrosis mothers' plea over 'life-changing' drug
Two mothers call on a drug firm and ministers to reach a deal over a 'life-changing' treatment. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - August 28, 2018 Category: Consumer Health News Source Type: news