Low-dose natural antimicrobial exacerbates chronic lung infection in cystic fibrosis
Respiratory failure caused by chronic lung infection with Pseudomonas aeruginosa bacteria is a common cause of death in patients with cystic fibrosis, a genetic disease that is common in individuals of European descent. A new study demonstrates that an antimicrobial peptide produced by human immune cells can promote mutations in the bacterium that make it more lethal. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 24, 2014 Category: Science Source Type: news

FDA grants orphan drug status to Bayer's bronchiectasis medicine Ciprofloxacin DPI
The US Food and Drug Administration (FDA) has granted orphan drug designation for Bayer HealthCare's investigational Ciprofloxacin Dry Powder for Inhalation (Ciprofloxacin DPI) to treat patients with non-cystic fibrosis bronchiectasis (NCFB). (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - April 24, 2014 Category: Pharmaceuticals Source Type: news

Low-dose natural antimicrobial exacerbates chronic lung infection in cystic fibrosis
(PLOS) Respiratory failure caused by chronic lung infection with Pseudomonas aeruginosa bacteria is a common cause of death in patients with cystic fibrosis, a genetic disease that is common in individuals of European descent. A study published on April 24 in PLOS Pathogens demonstrates that an antimicrobial peptide produced by human immune cells can promote mutations in the bacterium that make it more lethal. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 24, 2014 Category: Infectious Diseases Source Type: news

Pharma company Opko acquires smart inhaler startup for at least $10M
Biopharmaceutical company Opko Health has acquired Israeli smart inhaler company Inspiro Medical for a sum in “the low eight figures”, according to Opko’s Director of Strategic Investment Les Funtleyder. The company will be using Inspiro’s Inspiromatic technology to develop an app-connected inhaler that will be bundled with a forthcoming new drug for asthma, COPD, and [...] (Source: mobihealthnews)
Source: mobihealthnews - April 17, 2014 Category: Information Technology Authors: Jonah Comstock Tags: Uncategorized asthma connected inhaler COPD cystic fibrosis Inspiro Medical Inspiromatic mobile health mergers and acquisitions Opko Health pharma smart inhaler Source Type: news

The Economist explains: Why gene therapy just got easier
SOME diseases, such as haemophilia and cystic fibrosis, are caused by broken genes. Doctors have long dreamed of treating them by adding working copies of these genes to cells in the relevant tissue (bone marrow and the epithelium of the lung respectively, in these two cases). This has proved hard. There have been a handful of qualified successes over the years, most recently involving attempts to restore vision to people with gene-related blindness. But this sort of gene therapy is likely to remain experimental and bespoke for a long time, as it is hard to get enough genes into enough cells in solid tissue to have a meani...
Source: Biotechnology - April 8, 2014 Category: Biotechnology Source Type: news

Honoring Tim
Tim Packhem touched—and saved—a lot of lives. It’s an impressive thing to say about anyone, but the fact that Tim could affect so many, in so short a time, is what makes him truly special. Those close to him affectionately knew him as “Tim-bo”—a friendly goofball who was quick with a joke or a hug. The kind of guy who walks up to you on your first day at a new school and invites you join him and his friends at the lunch table. At 16 years old, when Tim died from severe brain trauma after falling off a skateboard, the number of people who appreciated his carefree attitude became heartbrea...
Source: Thrive, Children's Hospital Boston - April 3, 2014 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Donate life how organ donation saves lives National Donate Life Month Pediatric Transplant Center (PTC) Source Type: news

Cystic Fibrosis
Title: Cystic FibrosisCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 3/26/2014 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - March 26, 2014 Category: Respiratory Medicine Source Type: news

Face of organ donor campaign dies from cystic fibrosis after new lungs could not be found for her
Kerry Thorpe, 23, from Suffolk, died last Friday because no lung donor could be found for her. She was the face of an organ donor campaign with the slogan 'Would You Give Her One?'. (Source: the Mail online | Health)
Source: the Mail online | Health - March 25, 2014 Category: Consumer Health News Source Type: news

'I'd rather have a smoker's lungs than die on the transplant list,' says mother-of-two desperate for new organs
Robyn Davidson suffers from cystic fibrosis and has been warned by her doctors she needs a transplant in order to survive. (Source: the Mail online | Health)
Source: the Mail online | Health - March 20, 2014 Category: Consumer Health News Source Type: news

CF Foundation and CF care expert partnership yields striking progress for people with cystic fibrosis
A decade of strategic efforts to improve care has had a key role in improving quality of life and added years to predicted survival for people with cystic fibrosis (CF) in the United States, according to the editors of a BMJ Quality & Safety supplement dedicated to the disease.Health outcomes for CF have improved dramatically following implementation of an innovative and aggressive plan to promote quality improvement at CF care centres. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 18, 2014 Category: Consumer Health News Tags: Cystic Fibrosis Source Type: news

Progress made for people with cystic fibrosis
A decade of strategic efforts to improve care has had a key role in improving quality of life and added years to predicted survival for people with cystic fibrosis in the United States. Process outcomes, such as more timely clinic visits, higher rates of flu vaccination, and more effective monitoring of associated problems, including diabetes and depression, have all improved. So too have key clinical outcomes, such as improved lung function and nutritional status, write the authors. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 18, 2014 Category: Science Source Type: news

CF Foundation and CF care expert partnership yields striking progress for people with cystic fibrosi
(BMJ-British Medical Journal) A decade of strategic efforts to improve care has had a key role in improving quality of life and added years to predicted survival for people with cystic fibrosis in the United States, according to the editors of a BMJ Quality & Safety supplement dedicated to the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 17, 2014 Category: Global & Universal Source Type: news

I'd gladly take a smoker's lungs and risk cancer - to end the hell of life on the waiting list
Cystic Fibrosis sufferer Poppy Roberts, 23, from Monmouth would rather risk with smoker's lungs after waiting for two years for a transplant. (Source: the Mail online | Health)
Source: the Mail online | Health - March 15, 2014 Category: Consumer Health News Source Type: news

Jessica Fults
Future Health ProfessionalsJessica Fults is serving the members of HOSA-Future Health Professionals as this year’s National Region II Vice President. She has been an active member in HOSA for three years, during which time she has volunteered with numerous organizations such as the Juvenile Diabetes Research Foundation and the Cystic Fibrosis Foundation. Jessica has been a competitor in Clinical Specialty at the state and national levels and has been a participant in the National Recognition Program. Jessica served as the president and senior advisor of her local chapter, and she also had the honor of being Tennessee...
Source: PHRMA - March 12, 2014 Category: Pharmaceuticals Authors: Julie Source Type: news

Dr. Ran Anbar is honored by Cystic Fibrosis Foundation
The first person ever to be honored by the Foundation, Anbar is being recognized for his work with patients and his research contributions aimed at finding better treatments for CF sufferers. (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - March 12, 2014 Category: Universities & Medical Training Source Type: news

Call for lung 'allocation' system
It is a “scandal” that one in three cystic fibrosis sufferers who are waiting for donated lungs die while on the transplant list, a charity has warned. (Source: Nursing Times Breaking News)
Source: Nursing Times Breaking News - March 10, 2014 Category: Nursing Source Type: news

Call for lung ‘allocation’ system
It is a “scandal” that one in three cystic fibrosis sufferers who are waiting for donated lungs die while on the transplant list, a charity has warned. (Source: HSJ)
Source: HSJ - March 10, 2014 Category: UK Health Source Type: news

VIDEO: Lung transplant rethink urged
The way the transplant system operates for patients who need new lungs is a "scandal" and needs to change, according to the Cystic Fibrosis Trust (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 10, 2014 Category: Consumer Health News Source Type: news

Research benefits surgeons making decisions on how to help their patients breathe easier
Computer simulations have been developed for aircraft design to improve treatment of human airways. Computational Fluid Dynamics, or CFD, uses computer algorithms to solve the flow of air or fluids for various applications. These algorithms are typically applied toward the design of aircraft. While designing an aircraft, CFD is often considered both an accurate and less expensive approach before investing in building models and testing in air tunnels. But over the past decade or so, the application of CFD to biological flows to study medically-related problems, including respiratory disorders has gained a great deal of int...
Source: ScienceDaily Headlines - March 4, 2014 Category: Science Source Type: news

Sweat Chloride Test (Cystic Fibrosis)
Title: Sweat Chloride Test (Cystic Fibrosis)Category: Procedures and TestsCreated: 2/11/1999 4:57:00 AMLast Editorial Review: 3/3/2014 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - March 3, 2014 Category: Respiratory Medicine Source Type: news

Couple with cystic fibrosis have healthy baby boy
Chris and Marylee Kiernan, both 32, from Falkirk, had been trying for a baby for nine years before they conceived Alexander. (Source: the Mail online | Health)
Source: the Mail online | Health - February 27, 2014 Category: Consumer Health News Source Type: news

Is a 'buttery' molecule behind cystic fibrosis flare-ups?
A lung-damaging molecule has been discovered in higher concentrations in cystic fibrosis patients during symptom flare-ups. This molecule, which has a buttery flavor and is the main ingredient in microwave popcorn flavoring, is toxic and has been implicated in damaging the lungs of popcorn factory workers. Results of the new research indicate that it might play an important role in microbial infections of the lung suffered by people with cystic fibrosis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 23, 2014 Category: Science Source Type: news

Is a 'buttery' molecule behind cystic fibrosis flare-ups?
(San Diego State University) Katrine Whiteson and colleagues identified a lung-damaging molecule in higher concentrations in cystic fibrosis patients during symptom flare-ups. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 21, 2014 Category: Biology Source Type: news

Study Confirms Kalydeco Efficacy in CF Subset (CME/CE)
(MedPage Today) -- Ivacaftor (Kalydeco) substantially cut IV treatment needs while improving lung function in severe cystic fibrosis with the G551D mutation, a small study showed. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - February 19, 2014 Category: Infectious Diseases Source Type: news

CURx Pharmaceuticals Announces License Agreement with Gilead Sciences
SAN DIEGO, Feb. 19, 2014 -- (Healthcare Sales & Marketing Network) -- CURx Pharmaceuticals today announced it has entered into a global license agreement with Gilead Sciences, Inc. for development of Fosfomycin:Tobramycin for Inhalation (FTI) to treat Pse... Biopharmaceuticals, Drug Delivery, LicensingCURx Pharmaceuticals, Gilead Sciences, Fosfomycin, Tobramycin, cystic fibrosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 19, 2014 Category: Pharmaceuticals Source Type: news

Cystic Fibrosis Therapeutics in Major Developed Markets to 2019 |...
ResearchMoz.us include new market research report "Cystic Fibrosis Therapeutics in Major Developed Markets to 2019" to its huge collection of research reports. Full Report @...(PRWeb February 06, 2014)Read the full story at http://www.prweb.com/releases/2014/02/prweb11560471.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - February 8, 2014 Category: Pharmaceuticals Source Type: news

Cystic fibrosis sufferer defies her condition to become a personal trainer
Sophie Holmes, 22, from Southend-on-Sea, wanted to 'make her health her life' so decided to qualify as a personal trainer. (Source: the Mail online | Health)
Source: the Mail online | Health - January 29, 2014 Category: Consumer Health News Source Type: news

Jessica Fults
HOSA-Future Health ProfessionalsJessica Fults is serving the members of HOSA-Future Health Professionals as this year’s National Region II Vice President. She has been an active member in HOSA for three years, during which time she has volunteered with numerous organizations such as the Juvenile Diabetes Research Foundation and the Cystic Fibrosis Foundation. Jessica has been a competitor in Clinical Specialty at the state and national levels and has been a participant in the National Recognition Program. Jessica served as the president and senior advisor of her local chapter, and she also had the honor of being Tenn...
Source: PHRMA - January 22, 2014 Category: Pharmaceuticals Authors: Jon Tripp Source Type: news

Mother discovers her 'asthma' is actually life-threatening cystic fibrosis
EXCLUSIVE: Natalie Crawford, 31, from Northampton, was finally diagnosed at the age of 28 when a scan showed her unborn baby, Preston, had the condition. (Source: the Mail online | Health)
Source: the Mail online | Health - January 21, 2014 Category: Consumer Health News Source Type: news

Woman pays tribute to husband who donated TWO organs to save her life
David Whaymand, 39, of Ingatestone, Essex, donated a second bodily organ to his wife Carolyn, who suffers from cystic fibrosis. Now the 40-year-old solicitor has a special message of thanks to her beloved husband. (Source: the Mail online | Health)
Source: the Mail online | Health - December 24, 2013 Category: Consumer Health News Source Type: news

Vertex cystic fibrosis drug misses trial goal, helps some
(Reuters) - Vertex Pharmaceuticals Inc's Kalydeco cystic fibrosis drug failed to meet the main goal of a late-stage study aimed at expanding its use into patients with a specific gene mutation associated with the rare, life-threatening lung disease, the company said on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - December 19, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Vertex's cystic fibrosis drug misses goal but helps some adults
(Reuters) - Vertex Pharmaceuticals Inc said on Thursday that ivacaftor, an experimental drug to treat cystic fibrosis, failed to meet its targeted treatment goal in a late-stage study in people aged 6 and older with the "R117H" gene mutation. (Source: Reuters: Health)
Source: Reuters: Health - December 19, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Best friends dying of a lung disease receive life-saving transplants on same DAY
Kirstie Tancock, 24, and Katie Gammon, 15, from Devon, both suffer from cystic fibrosis. Katie was so ill she'd been transferred to a hospice. (Source: the Mail online | Health)
Source: the Mail online | Health - December 17, 2013 Category: Consumer Health News Source Type: news

Cystic fibrosis patients collect Beads of Courage
Children tell their story using colorful beads that commemorate milestones achieved in their unique treatment path. (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - December 13, 2013 Category: Universities & Medical Training Source Type: news

New drug approach developed that could lead to cures for a wide range of diseases
A team led by a longtime Oregon Health & Science University researcher has demonstrated in mice what could be a revolutionary new technique to cure a wide range of human diseases - from cystic fibrosis to cataracts to Alzheimer's disease - that are caused by "misfolded" protein molecules.Misfolded protein molecules, caused by gene mutation, are capable of maintaining their function but are misrouted within the cell and can't work normally, thus causing disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 12, 2013 Category: Consumer Health News Tags: Genetics Source Type: news

'Pruney' Palms Show CF Tx Response?
(MedPage Today) -- How quickly do hands pucker in the water? Slowed wrinkling could mean cystic fibrosis patients are responding to ivacaftor (Kalydeco), a case report suggested. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - December 11, 2013 Category: Pediatrics Source Type: news

MUC5B may be key to curing infections from common colds to deadly lung diseases
An international team of researchers has zeroed in on a protein that plays a key role in many lung-related ailments, from seasonal coughing and hacking to more serious diseases such as MRSA infections and cystic fibrosis.The finding advances knowledge about this range of illnesses and may point the way to eventually being able to prevent infections such as MRSA.The key protein is called MUC5B. It's one of two sugar-rich proteins, with similar molecular structure, that are found in the mucus that normally and helpfully coats airway surfaces in the nose and lung. The other is MUC5AC. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 11, 2013 Category: Consumer Health News Tags: Respiratory / Asthma Source Type: news

OHSU researchers develop new drug approach that could lead to cures for wide range of diseases
(Oregon Health & Science University) A team led by a longtime Oregon Health & Science University researcher has demonstrated in mice what could be a revolutionary new technique to cure a wide range of human diseases -- from cystic fibrosis to cataracts to Alzheimer's disease -- that are caused by "misfolded" protein molecules. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 9, 2013 Category: Global & Universal Source Type: news

From common colds to deadly lung diseases, 1 protein plays key role
(University of Colorado Denver) An international team of researchers has zeroed in on a protein that plays a key role in many lung-related ailments, from seasonal coughing and hacking to more serious diseases such as MRSA infections and cystic fibrosis.The finding advances knowledge about this range of illnesses and may point the way to eventually being able to prevent infections such as MRSA. The key protein is called MUC5B. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - December 8, 2013 Category: Global & Universal Source Type: news

Airway Inflammation in Cystic FibrosisAirway Inflammation in Cystic Fibrosis
Find out about efforts to uncover an inflammatory biomarker predictive for the clinical course of cystic fibrosis. Thorax (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 4, 2013 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

New technique for testing drugs to treat cystic fibrosis and epilepsy
Researchers from the University of Southampton, in collaboration with researchers at the University of Quebec at Montreal, have developed a new microsystem for more efficient testing of pharmaceutical drugs to treat diseases such as cystic fibrosis, MG (myasthenia gravis) and epilepsy.A large percentage of pharmaceutical drugs target ion channels, which are proteins found in a cell's membrane, that play a pivotal role in these serious disorders and that are used to test the effectiveness of new drugs. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 30, 2013 Category: Consumer Health News Tags: Pharma Industry / Biotech Industry Source Type: news

FDA Approves New Gene-Sequencing Devices
The FDA approved four "next-generation" gene-sequencing devices with the potential to make faster and more precise diagnoses of cystic fibrosis. (Source: WSJ.com: Health)
Source: WSJ.com: Health - November 20, 2013 Category: Pharmaceuticals Tags: PAID Source Type: news

Medical Breakthrough Gives Couples Who Want Children New Hope
function cbs_video_wnplayer_9548969_start() { var WNVideoCanvas_vid9548969 = new WNVideoWidget("WNVideoCanvas", "WNVideoCanvas_vid9548969", "2"); //Playback options WNVideoCanvas_vid9548969.SetVariable("widgetId", 9548969); WNVideoCanvas_vid9548969.SetVariable("addThisDivId", "WNVideoCanvas_vid9548969_addThis"); WNVideoCanvas_vid9548969.SetVariable("incanvasAdDivId", "WNVideoCanvas_vid9548969_adDiv"); WNVideoCanvas_vid9548969.SetVariable("clipId", "9548969"); // Controls options WNVideoCanvas_vid9548969.Set...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 20, 2013 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen cystic fibrosis Dr. Ian Hardy Fragile X Pompeii Disease Preimplantation Genetic Diagnosis Spinal Muscular Atrophy Tay-Sachs Source Type: news

The thyroid gland and cystic fibrosis
Research in the College of Veterinary Medicine at Kansas State University is leading to a better understanding of the molecular interactions in the thyroid gland related to cystic fibrosis. A genetic disorder, cystic fibrosis affects the function of epithelia, the tissues formed of cells that secrete and absorb an array of substances important for health. The university's Peying Fong, associate professor of anatomy and physiology, has received a $285,000 grant from the Department of Health and Human Services in support of her study, "CFTR Regulation of Thyroid Transport... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 31, 2013 Category: Consumer Health News Tags: Cystic Fibrosis Source Type: news

Queen's University in €6m bid to find new Cystic Fibrosis treatments
(Queen's University Belfast) The new global program, known as CF Matters, aims to develop personalized antibiotic treatments for these chest infections. The work could revolutionize the practice of antibiotic prescription and limit resistance to the drugs globally. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 29, 2013 Category: Global & Universal Source Type: news

Thyroid project sheds light on molecular processes related to cystic fibrosis
(Kansas State University) Veterinary medicine research is leading to a better understanding of the molecular interactions in the thyroid gland related to cystic fibrosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 29, 2013 Category: Global & Universal Source Type: news

Study on transitioning cystic fibrosis care
Children's National pediatrician and researcher, Lisa Tuchman, MD, MPH, co-authored a new study on cystic fibrosis (CF) care that found patients had a less rapid decline in pulmonary function and no other significant health-related changes after transitioning from pediatric to adult care. The findings of this study contradict reports of negative health outcomes after transition from pediatric to adult care for other chronic childhood illnesses such as HIV and sickle cell disease. The study was published online in Pediatrics, the official journal of the American Academy of Pediatrics... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 25, 2013 Category: Consumer Health News Tags: Cystic Fibrosis Source Type: news

Did Insmed Release Shaky Data for its Arikace Drug?
Financial reporters from TheStreet.com question Insmed's analysis of Arikace Cystic Fibrosis study (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - October 24, 2013 Category: Pharmaceuticals Source Type: news

Ivacaftor Treatment of Cystic Fibrosis PatientsIvacaftor Treatment of Cystic Fibrosis Patients
Current cystic fibrosis care is supportive, but recent breakthroughs have occurred with the advent of novel therapeutic strategies that assist the function of mutant CFTR proteins. Therapeutic Advances in Respiratory Disease (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 23, 2013 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Children's National researcher co-authors study on transitioning cystic fibrosis care
(Children's National Medical Center) Children's National pediatrician and researcher, Lisa Tuchman, M.D., M.P.H., co-authored a new study on cystic fibrosis care that found patients had a less rapid decline in pulmonary function and no other significant health-related changes after transitioning from pediatric to adult care. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 23, 2013 Category: Global & Universal Source Type: news