Combo Treatment for Cystic Fibrosis Shows Promise
Title: Combo Treatment for Cystic Fibrosis Shows PromiseCategory: Health NewsCreated: 5/18/2015 12:00:00 AMLast Editorial Review: 5/18/2015 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - May 18, 2015 Category: Respiratory Medicine Source Type: news

New treatment brings hope on cystic fibrosis
Professor Stuart Elborn, who led the European part of the trial at Queen's University, Belfast, described the drug as a 'breakthrough'. (Source: the Mail online | Health)
Source: the Mail online | Health - May 18, 2015 Category: Consumer Health News Source Type: news

Combination Treatment for Cystic Fibrosis Shows Promise
Researchers say therapy could help 15,000 people in United States alone (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - May 18, 2015 Category: Respiratory Medicine Authors: webmaster at doctorslounge.com Tags: Pharmacy, Pulmonology, Research, News, Source Type: news

Promising research trials find new combination of drugs treat underlying cause of most common form of cystic fibrosis
Results from clinical trials show that a new combination of medications can successfully treat the underlying cause of cystic fibrosis for patients 12 and older with two copies of the F508del gene mutation -- the most common form of the life-threatening, genetic disease found in over half of the CF population. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 17, 2015 Category: Science Source Type: news

Combination Treatment for Cystic Fibrosis Shows Promise
Researchers say therapy could help 15,000 people in United States alone Source: HealthDay Related MedlinePlus Pages: Cystic Fibrosis, Genes and Gene Therapy, Medicines (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 17, 2015 Category: Consumer Health News Source Type: news

Cystic fibrosis treatment found to improve lives of sufferers in trials
Combination of lumacaftor and ivacaftor modifies genetic defect that causes half of cases of disease that affects 10,000 UK children Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - May 17, 2015 Category: Science Authors: Sarah Boseley Health editor Tags: Drugs Health UK news Science Society Genetics Source Type: news

'Groundbreaking' cystic fibrosis drug
A "groundbreaking" cystic fibrosis therapy could profoundly improve quality of life, say doctors. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - May 17, 2015 Category: Consumer Health News Source Type: news

Lumacaftor/Ivacaftor Combo Helps Common CF Mutation (CME/CE)
(MedPage Today) -- Phase III trial finds drug combo boosts forced expiratory volume in homozygous Phe508del cystic fibrosis patients. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - May 17, 2015 Category: Pediatrics Source Type: news

Groundbreaking treatment for patients with cystic fibrosis
(Ann & Robert H. Lurie Children’s Hospital of Chicago) Groundbreaking treatment that uses two medications that target the most common genetic cause of cystic fibrosis shows lung function improvement and lowers the rate of pulmonary exacerbations. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 17, 2015 Category: Global & Universal Source Type: news

Eurovision Song Contest singer Bianca Nicholas on living with cystic fibrosis
LIVING with cystic fibrosis hasn’t prevented Eurovision Song Contest hopeful Bianca Nicholas from fulfilling her dream. (Source: Daily Express - Health)
Source: Daily Express - Health - May 17, 2015 Category: Consumer Health News Source Type: news

ASCO, Denali, Vertex: Pharma News You May Have Missed This Week
A flood of cancer drug data poured into the public domain, a huge neuroscience startup got financed, and an FDA advisory panel gave a green light to an important combo drug for cystic fibrosis. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - May 16, 2015 Category: Pharmaceuticals Authors: Luke Timmerman Source Type: news

What You Need To Know In Biotech: An ASCO Disappointment, Big Money In Brains And A New CF Drug
A flood of cancer drug data poured into the public domain, a huge neuroscience startup got financed, and an FDA advisory panel gave a green light to an important combo drug for cystic fibrosis. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - May 16, 2015 Category: Pharmaceuticals Authors: Luke Timmerman Source Type: news

Unexplainable Grace
The simplest of things can hold the greatest significance and beauty. They can ignite a fire within, overwhelm us with gratitude and revive the spirit of hope that dwells inside each of us. We can search far and wide seeking out beauty in the grandest of forms, but sometimes the most substantial beauty is in the simplest of existence. Simple Beauty It's incredible how something as unassuming as a white piece of paper with a few numbers can carry so much meaning and beauty. It really means so many things, but most of all that piece of paper represents the life within every breath I take. It represents the grace I've been ...
Source: Healthy Living - The Huffington Post - May 14, 2015 Category: Consumer Health News Source Type: news

CF Combo Drug Wins FDA Panel Backing
(MedPage Today) -- If approved, drug could be given to large numbers of cystic fibrosis patients. (Source: MedPage Today Pulmonary)
Source: MedPage Today Pulmonary - May 13, 2015 Category: Respiratory Medicine Source Type: news

Newborns With Unclear CF Tests May Develop Disease LaterNewborns With Unclear CF Tests May Develop Disease Later
By age 3 years, 11% of infants with inconclusive results on newborn cystic fibrosis testing developed the disease, underscoring the need for added monitoring. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 13, 2015 Category: Consumer Health News Tags: Pediatrics News Source Type: news

FDA Panel Backs Vertex Cystic-Fibrosis Drug Orkambi
Vertex Pharmaceuticals’ experimental cystic fibrosis treatment Orkambi won the backing of an FDA advisory panel, which recommended approval. (Source: WSJ.com: Health)
Source: WSJ.com: Health - May 13, 2015 Category: Pharmaceuticals Tags: PAID Source Type: news

FDA panel fails to find Vertex lumacaftor positive for cystic fibrosis
WASHINGTON (Reuters) - A divided U.S. Food and Drug Administration advisory committee on Tuesday said research data does not show definitively that Vertex Pharmaceutical Inc's drug lumacaftor has a positive effect on cystic fibrosis patients when used in combination with the company's approved therapy, Kalydeco. (Source: Reuters: Health)
Source: Reuters: Health - May 12, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

Cystic Fibrosis Drug Wins Approval of F.D.A. Advisory Panel
The drug, which directly counteracts the genetic defect that causes cystic fibrosis, might help as many as half of American patients. (Source: NYT Health)
Source: NYT Health - May 12, 2015 Category: Consumer Health News Authors: ANDREW POLLACK Tags: Cystic Fibrosis Drugs (Pharmaceuticals) Food and Drug Administration Vertex Pharmaceuticals Inc Source Type: news

FDA panel recommends approval for Vertex cystic fibrosis drug
Correction: An earlier version of this story mischaracterized the FDA's approval process today. The FDA has not yet approved Vertex's drug; an FDA advisory panel has recommended its approval. The Food and Drug Administration's advisory committee has recommended that the FDA approve a new drug from Vertex Pharmaceuticals, which has the potential to help treat an additional 8,500 patients with cystic fibrosis. The drug, Orkambi, has the potential to make the 26-year-old Boston-based drugmaker (Nasdaq:… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - May 12, 2015 Category: American Health Authors: Jessica Bartlett Source Type: news

Vertex's Cystic-Fibrosis Drug Faces Big Test
An FDA advisory committee on Tuesday will consider whether to recommend approval of biotech Vertex’s experimental cystic-fibrosis drug, Orkambi. (Source: WSJ.com: Health)
Source: WSJ.com: Health - May 11, 2015 Category: Pharmaceuticals Tags: PAID Source Type: news

FDA staff questions value of Vertex's cystic fibrosis combo
(Reuters) - Staff reviewers from the U.S. FDA questioned whether Vertex Pharmaceuticals Inc's experimental combination therapy for cystic fibrosis had an added benefit over the company's already approved therapy, Kalydeco, in patients with the most common genetic mutation behind the deadly disease. (Source: Reuters: Health)
Source: Reuters: Health - May 8, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

Dr. Elizabeth Tullis of St. Michael’s Hospital appointed to Cystic Fibrosis Canada Chair in Adult Cystic Fibrosis Research
(Source: St. Michael's Hospital News and Media)
Source: St. Michael's Hospital News and Media - May 8, 2015 Category: Hospital Management Tags: Hospital News Source Type: news

Cystic fibrosis sufferer eats 8,000 calories a day without putting on weight
The svelte 20-year-old, from Amlwch, Anglesey, munches her way through fry-ups, crisps, chocolate and snacks everyday just to maintain her 7st 7lbs weight. (Source: the Mail online | Health)
Source: the Mail online | Health - May 8, 2015 Category: Consumer Health News Source Type: news

Female cystic fibrosis patients need more contraceptive guidance, study finds
(University of Pennsylvania School of Medicine) Only half of women with cystic fibrosis report using contraception and frequently apt to become pregnant unintentionally, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. As recently as the 1960s, children with cystic fibrosis -- an inherited disease that causes thick, sticky mucus to form in the lungs, pancreas, and other organs -- often died before attending elementary school. Today many people with the disease live into their 30s, 40s and beyond. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 7, 2015 Category: Global & Universal Source Type: news

​Cambridge company says parents should be screened for genetic muscular disorder
Cambridge-based genetics company Good Start Genetics Inc. said that a large percentage of parents are believed to be carriers of the genetic mutation behind spinal muscular atrophy, findings the company hopes encourage organizations to add the disease to suggested screenings. According to recent data published by Good Start Genetics, of 63,080 patients from in vitro fertilization centers, Good Start detected 1,067 genetic carriers of the disease. “It’s not much less prevalent than cystic fibrosis,”… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - May 6, 2015 Category: American Health Authors: Jessica Bartlett Source Type: news

DNA modification could wipe out genetic diseases like cystic fibrosis
EXCLUSIVE: Christopher Gyngell, a research fellow in neuroethics at Oxford University, argues that far from being wrong, the research on human gene editing is' ethically imperative'. (Source: the Mail online | Health)
Source: the Mail online | Health - May 6, 2015 Category: Consumer Health News Source Type: news

Tiny Corbus Looks to Take on Vertex With Cystic Fibrosis DrugTiny Corbus Looks to Take on Vertex With Cystic Fibrosis Drug
Corbus Pharmaceuticals Holdings Inc's experimental drug for cystic fibrosis could be a real money spinner and pose a challenge to rival Vertex Pharmaceuticals Inc's successful treatment, Kalydeco. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 6, 2015 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

List of Physically Disabled World Leaders & Politicians
Though there are many types of disability the list below only covers physically disabled world leaders and politicians. Physical disabilities may arise from conditions such as congenital deformities, spina bifida and/or hydrocephalus, muscular dystrophy, cerebral palsy, brittle bones, haemophilia, cystic fibrosis or severe accidental injury. The characteristics of people with physical disabilities are as unique to the individuals as the conditions that created their special needs. Physical Disability Characteristics Can Include: Paralysis. Unsteady gait. Altered muscle tone. Loss of, or inability to use, one or more l...
Source: Disabled World - May 5, 2015 Category: Disability Tags: Awareness - Disability Source Type: news

Tiny Corbus looks to take on Vertex with experimental lung drug
(Reuters) - Corbus Pharmaceuticals Holdings Inc's experimental drug for cystic fibrosis, a rare lung-scarring disease, could be a real money spinner and pose a challenge to rival Vertex Pharmaceuticals Inc's successful treatment, Kalydeco. (Source: Reuters: Health)
Source: Reuters: Health - May 4, 2015 Category: Consumer Health News Tags: healthNews Source Type: news

£10 test for lung patients could flag up potentially deadly infections early
The first version of the test will be made available to the 10,000 British patients with genetic disease cystic fibrosis (CF), which causes respiratory problems along with other symptoms. (Source: the Mail online | Health)
Source: the Mail online | Health - May 3, 2015 Category: Consumer Health News Source Type: news

Advanced Inhalation Therapies Granted European Orphan Drug Designation for Nitric Oxide for the Treatment of Cystic Fibrosis
REHOVOT, Israel and NEW YORK, May 1, 2015 -- (Healthcare Sales & Marketing Network) -- Advanced Inhalation Therapies Ltd (AIT), a leading anti-microbial therapeutic company, announced that the European Commission, acting on the recommendation from the Com... Biopharmaceuticals, RegulatoryAdvanced Inhalation Therapies, AIT-CF, nitric oxide, cystic fibrosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 1, 2015 Category: Pharmaceuticals Source Type: news

'Salty Girls' Photo Series Challenges Notions Of Beauty And Cystic Fibrosis
Photographer and art director Ian Pettigrew was working on a photo series he called "Just Breathe: Cystic Fibrosis" when he realized the majority of his models were beautiful young women. "'Salty Girls' sprung out from my first book, Just Breathe, which focused just on adults with CF," the 45-year-old Ontario native, who also has cystic fibrosis, told The Huffington Post by email Wednesday. "As that project progressed it was clear that there was a disproportionate amount of women, and it was remarked that 'this project is just a bunch of hot women with cystic fibrosis.'" Thus began the &qu...
Source: Healthy Living - The Huffington Post - April 29, 2015 Category: Consumer Health News Source Type: news

Cystic fibrosis sufferer Ben Mudge lands career as a fitness model 
Although working as a personal trainer and fitness model allows Ben Mudge, 25, from Belfast, to to make a living, being an expert in fitness and nutrition helps him fight off potentially fatal illnesses. (Source: the Mail online | Health)
Source: the Mail online | Health - April 28, 2015 Category: Consumer Health News Source Type: news

Yale scientists use gene editing to correct mutation in cystic fibrosis
(Yale University) Yale researchers successfully corrected the most common mutation in the gene that causes cystic fibrosis, a lethal genetic disorder. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 27, 2015 Category: Biology Source Type: news

Boy's pills video gets 650,000 hits
An online video of a six-year-old boy swallowing tablets for cystic fibrosis is viewed more than 650,000 times. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - April 20, 2015 Category: Consumer Health News Source Type: news

Video of six-year-old taking daily dose of nine pills to treat cystic fibrosis goes viral
Six-year-old Jesse James O'Brien's video of his daily routine to treat cystic fibrosis quickly becomes an online sensation (Source: Telegraph Health)
Source: Telegraph Health - April 20, 2015 Category: Consumer Health News Tags: cystic fibrosis 6 boy facebook pill viral video 9 viral video ipswich Kesgrave tablets nine watch daily dose six year old suffolk Source Type: news

A Voice Found
The voice. It is the purest reflection of one's self and is the instrument from which our passions pour. It carries our emotions, gives wings to the thoughts that resonate within, and transforms our ideas into purpose. It embodies the complexity of our entire being, yet it is born out of a simple beautiful breath. Defining Who I Am Singing has been at the very core of who I am for as long as I can remember. Just like cystic fibrosis, it has always been a part of me. While there is truly nothing else that feeds my soul the way singing does, it isn't singing itself that has made my life so incredibly full. What truly gives...
Source: Healthy Living - The Huffington Post - April 16, 2015 Category: Consumer Health News Source Type: news

Inseparable twins, 23, die within three days of each other after battling cystic fibrosis all their lives 
John and Marie Wright, 23, from Ipswich, Suffolk, who were diagnosed with the degenerative genetic condition as infants, had always done everything together. (Source: the Mail online | Health)
Source: the Mail online | Health - April 15, 2015 Category: Consumer Health News Source Type: news

Battling to save their lives
A girl with cystic fibrosis messaged a boy with cystic fibrosis, and their lives were changed forever. Now she's battling to save her life and their love. (Source: CNN.com - Health)
Source: CNN.com - Health - April 3, 2015 Category: Consumer Health News Source Type: news

A real 'Fault in Our Stars' couple
Late one night on Facebook, a girl with cystic fibrosis messaged a boy with cystic fibrosis, and both their lives were changed forever. (Source: CNN.com - Health)
Source: CNN.com - Health - April 2, 2015 Category: Consumer Health News Source Type: news

A battle to save their lives, and their love
A girl with cystic fibrosis messaged a boy with cystic fibrosis, and their lives were changed forever. Now she's battling to save her life and their love. (Source: CNN.com - Health)
Source: CNN.com - Health - April 2, 2015 Category: Consumer Health News Source Type: news

2015: A real 'Fault in Our Stars' couple
Late one night on Facebook, a girl with cystic fibrosis messaged a boy with cystic fibrosis, and both their lives were changed forever. (Source: CNN.com - Health)
Source: CNN.com - Health - April 2, 2015 Category: Consumer Health News Source Type: news

Meet the Pragers, a real 'Fault in Our Stars' couple
Late one night on Facebook, a girl with cystic fibrosis messaged a boy with cystic fibrosis, and both their lives were changed forever. (Source: CNN.com - Health)
Source: CNN.com - Health - April 2, 2015 Category: Consumer Health News Source Type: news

Signs of Life
They are embellishments: signs of life. They're the reminder of another day, our journey, and reflect the gift of living. They are marks that cannot be erased. They are not battle scars, but the signs of truly living. The Lasting Impact All that remains is a small pink dot about the size of a pencil eraser. It subtly adorns the underside of my arm and gives little outward suggestion to the devastation it has witnessed and the battle it has helped to fight these past months. However, it isn't alone. It is accompanied by numerous identical marks that have faded over time but still remain to tell of their own past battles. ...
Source: Healthy Living - The Huffington Post - March 29, 2015 Category: Consumer Health News Source Type: news

Demographic, Clinical, and Lab Parameters of Cystic FibrosisDemographic, Clinical, and Lab Parameters of Cystic Fibrosis
How have clinical outcomes in cystic fibrosis differed between the last two decades? BMC Pulmonary Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 27, 2015 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Precision medicine is coming, but not anytime soon
President Obama’s announcement of a Precision Medicine Initiative was one of the few items in this year’s State of the Union address to garner bipartisan support. And for good reason. Precision medicine, also known as personalized medicine, offers the promise of health care — from prevention to diagnosis to treatment — based on your unique DNA profile. Who wouldn’t want that? We’ve already had a taste of precision medicine. Relatively low-tech therapies like eyeglasses, orthotic devices, allergy treatments, and blood transfusions have long been personalized for the individual. Genetic an...
Source: New Harvard Health Information - March 26, 2015 Category: Consumer Health News Authors: Beverly Merz Tags: Health care personalized health care precision medicine Source Type: news

How Patients Are Driving Research & Cures For Their Own Rare Diseases
TRENTON, N.J. (AP) — The global pharmaceutical industry is pouring billions of dollars into developing treatments for rare diseases, which once drew little interest from major drugmakers but now point the way toward a new era of innovative therapies and big profits. The investments come as researchers harness recent scientific advances, including the mapping of the human genome, sophisticated and affordable genetic tests and laboratory robots that can screen thousands of compounds per hour in search of the most potent ones. "It's a very, very promising time," said Jimmy Lin, a National Institutes of Healt...
Source: Science - The Huffington Post - March 25, 2015 Category: Science Source Type: news

Lung Transplant Patients in the UK Fare Better Than Publicly Insured Americans - 3/24/15
Publicly insured Americans who undergo lung transplantation for cystic fibrosis fare markedly worse in the long run than both publicly insured patients in the United Kingdom and privately insured Americans, according to the results of a study conducted by researchers from Johns Hopkins in Baltimore and U.K. colleagues working in that nation’s government-funded National Health Service. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - March 24, 2015 Category: Research Source Type: news

Dylan Samuels who played for Manchester United now spends most of his time in hospital
Dylan Samuels was born with cystic fibrosis (CF), a genetic condition where mucus becomes thick and sticky, clogging up a sufferer’s lungs and digestive system. (Source: the Mail online | Health)
Source: the Mail online | Health - March 23, 2015 Category: Consumer Health News Source Type: news

Unraveling cystic fibrosis puzzle, taking it personally matters
(University of North Carolina at Charlotte) A comprehensive bioinformatics analysis of human lung bacteria from a uniquely detailed, long-term data set has discovered a previously unknown relationship between population changes in a single bacterial species and subsequent flare-ups of disease in cystic fibrosis. The study was made possible by the unusual cooperation of a single cystic fibrosis patient -- the lead author in the study. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 23, 2015 Category: Biology Source Type: news