New Markers of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Function in Sweat
Conditions:   Cystic Fibrosis;   Biomarkers Intervention:   Diagnostic Test: Three Groups Assignment Sponsors:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain;   Université de Liège Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 20, 2019 Category: Research Source Type: clinical trials

Preventing Depression and Anxiety: A Trial of a Cystic Fibrosis-Specific Cognitive Behavioral Therapy Intervention
Condition:   Depression, Anxiety Interventions:   Behavioral: CF-CBT: A Cognitive-Behavioral Skills-Based Program to Promote Emotional Well-Being for Adults wtih Cystic Fibrosis;   Behavioral: Waitlist Control Sponsors:   Massachusetts General Hospital;   Cystic Fibrosis Foundation;   DeltaQuest Foundation, Inc.;   University at Buffalo;   University of Kansas Medical Center;   Stanford University;   Nicklaus Children's Hospital f/k/a Miami Children's Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 19, 2019 Category: Research Source Type: clinical trials

Effect of Roflumilast on Quality of Life, Lung Function and Mucus Properties in Patients With Non-cystic Fibrosis Bronchiectasis.
Condition:   Bronchiectasis Adult Interventions:   Drug: Roflumilast;   Drug: Placebo oral tablet Sponsor:   University of Sao Paulo General Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 17, 2019 Category: Research Source Type: clinical trials

Vertex Selects Triple Combination Regimen of VX-445, Tezacaftor and Ivacaftor to Submit for Global Regulatory Approvals in Cystic Fibrosis
BOSTON--(BUSINESS WIRE)--May 30, 2019-- Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced that it has selected the triple combination of the next-generation corrector VX-445 (elexacaftor), tezacaftor and ivacaftor to submit for... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - May 31, 2019 Category: Pharmaceuticals Source Type: clinical trials

Glycemic Characterization and Pancreatic Imaging Correlates in Cystic Fibrosis
Conditions:   Cystic Fibrosis;   Cystic Fibrosis-related Diabetes;   Cystic Fibrosis Liver Disease;   Pancreatic Steatosis;   Hepatic Steatosis Interventions:   Device: Frequently Sampled Oral Glucose Tolerance Test and CGM;   Radiation: MRI Pancreas and Liver Sponsor:   University Hospitals Cleveland Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 23, 2019 Category: Research Source Type: clinical trials

Microbial Biomarkers of EArly Pseudomonas Aeruginosa Colonization in CHildren With Cystic Fibrosis
Condition:   Cystic Fibrosis Intervention:   Diagnostic Test: collection of expectoration, stools and blood Sponsor:   University Hospital, Brest Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 13, 2019 Category: Research Source Type: clinical trials

Thermic Effect of Feeding in Cystic Fibrosis
Condition:   Cystic Fibrosis Interventions:   Dietary Supplement: Boost VHC;   Dietary Supplement: Ensure High Protein Sponsor:   Virginia Commonwealth University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 30, 2019 Category: Research Source Type: clinical trials

A Phase IIa, Randomized, Placebo-controlled, Double-blind, Cross-over Study to Evaluate Safety and Efficacy of Subcutaneous Administration of Anakinra in Patients With Cystic Fibrosis
Condition:   Cystic Fibrosis, 10011762 Intervention:   Drug: Anakinra Sponsor:   Heidelberg University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2019 Category: Research Source Type: clinical trials

A Study to Compare US Marketed Pancrelipase Drug Product With Drug Product Manufactured With a Modernized Process at an Alternate Manufacturing Site, in Participants With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis.
Condition:   Cystic Fibrosis Intervention:   Drug: Pancrelipase Sponsor:   AbbVie Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2019 Category: Research Source Type: clinical trials